DK2682382T3 - Fremgangsmåde til fremstilling af phenylacetamidforbindelse - Google Patents
Fremgangsmåde til fremstilling af phenylacetamidforbindelse Download PDFInfo
- Publication number
- DK2682382T3 DK2682382T3 DK13178853.1T DK13178853T DK2682382T3 DK 2682382 T3 DK2682382 T3 DK 2682382T3 DK 13178853 T DK13178853 T DK 13178853T DK 2682382 T3 DK2682382 T3 DK 2682382T3
- Authority
- DK
- Denmark
- Prior art keywords
- phenyl
- group
- compound
- formula
- dimethylphenoxymethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/06—Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Claims (8)
- FREMGANGSMÅDE TIL FREMSTILLING AF PHENYLACETAMIDFORBINDELSE Patentkrav1. Fremgangsmåde til fremstilling af en phenylacetamidforbindelse repræsenteret ved formel (1):hvori Q repræsenterer et hydrogenatom eller et halogenatom, R2 repræsenterer et hydrogenatom, R4 repræsenterer en alkylgruppe med 1 til 4 carbonatomer, Ar repræsenterer en phenylgruppe, som kan være ikke-substituteret eller substituteret med alkyl med 1 til 4 carbonatomer eller-halogen, R3 repræsenterer R4 ; omfattende omsætning af en phenylacetamidforbindelse repræsenteret ved formel (2):hvori Q, R4 og Ar nar samme betydninger som defineret i det foregående; med et dialkyIsnifat repræsenteret ved formel (3) :hvori R4 har samme betydning som defineret i det foregående; i tilstedeværelse af en base.
- 2. Fremstillingsmetode ifølge krav 1, hvori Ar er en 2,5-dimethylphenylgruppe eller en 2-methylphenyIgruppe.
- 3. Fremstillingsmetode ifølge krav 1, hvori Ar er en 2,5-dimethylphenylgruppe.1. Fremstillingsmetode ifølge krav 1, hvori R4 er en methylgruppe.
- 5. Fremstillingsmetode ifølge krav 1, hvori basen er en a 1 k a 1 i me t a 1 h y d r o x i d.
- 6. Fremstillingsmetode ifølge krav 1, hvori en eddikesyreesterforbindelse repræsenteret ved formel (4):hvori Q repræsenterer et hydrogenatom eller et halogenatom, Ar repræsenterer en phenylgruppe, som kan være ikke-substituteret eller substituteret med alkyl med 1 til 4 carbonatomer eller halogen, og R1 repræsenterer en alkylgruppe med 1 til 4 carbonatomer; omsættes med en aminforbindelse repræsenteret ved formel (5) :hvori R4 repræsenterer et hydrogenatom; x0r at opnå en phenylacetamidforbindelse repræsenteret ved formel (2): hvilken phenylacetamidforbindelse efterfølgende omsættes med diaiicylsulratet i overensstemmelse med fremstillingsmetoden ifølge krav 1. ''· Fremstillingsmetode ifølge krav 6, hvori omsætningen af eddisesyreesterforbindelsen repræsenteret ved formel (4) raed aminforbindelsen repræsenteret ved formel (5) udføres i tilstedeværelse af et alkoholopløsningsmiddel med 1 til 4 carbonatomer.
- 8. Fremstillingsmetode ifølge krav 6, hvori en mandelonitrilforbindelse repræsenteret ved formel (6):hvori Q repræsenterer et hydrogenatom eller et halogenatom, og Ar repræsenterer en phenylgruppe, som kan være ikke-subst. i tueret eller substitueret med alkyl med 1 til 4 carbonatomer eller halogen; omsættes med en alkoholforbindelse repræsenteret ved formel (7): R1-OH (7) hvori R1 repræsenterer en alkylgruppe med 1 til 4 c a r b o na t ome r; og en syre, og det resulterende produkt derefter omsættes med vand; for at opnå en eddikeesterforbindelse repræsenteret ved formel (4); hvilken eddikeesterforbindelse efterfølgende omsættes med aminforbindelsen i overensstemmelse med fremstillingsmetoden ifølge krav 6,
- 9. Fremstillingsmetode ifølge krav 1, hvori mandelonitrilforbindelsen repræsenteret ved formel (6):hvori Q repræsenterer et hydrogenatom eller et halogenatom, og Ar repræsenterer en phenylgruppe, som kan være ikke-substitueret eller substitueret med alkyl med 1 til 4 carbonatomer eller halogen; omsættes med 0,1 til 1 mol hydrogenchlorid og 1 til 4 mol vand, baseret på 1 mol af mandelonitrilforbindelsen; for at opnå phenylacetamidforbindelsen ifølge formel (2); h v i1k e n phe ny1a c e t ami dforb i ndelse efter f ø1ge nde omsættes med dialkylsulfatet i overensstemmelse med fremstillingsmetoden ifølge krav 1.
- 10. Fremgangsmåde til fremstilling ifølge krav 9, hvori omsætningen af mandelonitrilforbindelsen, der er repræsenteret ved formel (6), med hydrogenchlorid og vand udføres i tilstedeværelse af et aromatisk c a r b o n h y d r i d o p 1 ø s n i n g s m i d d e 1.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009032333 | 2009-02-16 | ||
| JP2009139899 | 2009-06-11 | ||
| JP2009232242 | 2009-10-06 | ||
| EP10741332.0A EP2397459B1 (en) | 2009-02-16 | 2010-02-12 | Method for producing phenylacetamide compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2682382T3 true DK2682382T3 (da) | 2017-01-09 |
Family
ID=42561896
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13178853.1T DK2682382T3 (da) | 2009-02-16 | 2010-02-12 | Fremgangsmåde til fremstilling af phenylacetamidforbindelse |
| DK10741332.0T DK2397459T3 (da) | 2009-02-16 | 2010-02-12 | Fremgangsmåde til fremstilling af en phenylacetamidforbindelse |
| DK13178854.9T DK2662352T3 (da) | 2009-02-16 | 2010-02-12 | Fremgangsmåde til fremstilling af phenylacetamidforbindelse |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10741332.0T DK2397459T3 (da) | 2009-02-16 | 2010-02-12 | Fremgangsmåde til fremstilling af en phenylacetamidforbindelse |
| DK13178854.9T DK2662352T3 (da) | 2009-02-16 | 2010-02-12 | Fremgangsmåde til fremstilling af phenylacetamidforbindelse |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8624062B2 (da) |
| EP (3) | EP2662352B1 (da) |
| JP (2) | JP5703568B2 (da) |
| KR (2) | KR101718173B1 (da) |
| CN (3) | CN103641731B (da) |
| AU (1) | AU2010214305B2 (da) |
| DK (3) | DK2682382T3 (da) |
| ES (3) | ES2607404T3 (da) |
| HU (2) | HUE031434T2 (da) |
| IL (3) | IL214470A (da) |
| LT (1) | LT2682382T (da) |
| PL (2) | PL2682382T3 (da) |
| TW (2) | TWI570098B (da) |
| WO (1) | WO2010093059A1 (da) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5417860B2 (ja) * | 2008-08-26 | 2014-02-19 | 住友化学株式会社 | α−ヒドロキシエステル類の製造方法 |
| ES2607404T3 (es) * | 2009-02-16 | 2017-03-31 | Sumitomo Chemical Company, Limited | Método para la producción de compuesto de fenilacetamida |
| JP2019516670A (ja) | 2016-04-12 | 2019-06-20 | シンジェンタ パーティシペーションズ アーゲー | 殺微生物性オキサジアゾール誘導体 |
| JP2019523224A (ja) | 2016-06-03 | 2019-08-22 | シンジェンタ パーティシペーションズ アーゲー | 殺微生物オキサジアゾール誘導体 |
| AR108745A1 (es) | 2016-06-21 | 2018-09-19 | Syngenta Participations Ag | Derivados de oxadiazol microbiocidas |
| US20200138028A1 (en) | 2016-07-22 | 2020-05-07 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| JP2019528252A (ja) | 2016-07-22 | 2019-10-10 | シンジェンタ パーティシペーションズ アーゲー | 殺微生物オキサジアゾール誘導体 |
| CN109476613A (zh) | 2016-07-22 | 2019-03-15 | 先正达参股股份有限公司 | 杀微生物的噁二唑衍生物 |
| WO2018029242A1 (en) | 2016-08-11 | 2018-02-15 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| WO2018055133A1 (en) | 2016-09-23 | 2018-03-29 | Syngenta Participations Ag | Microbiocidal tetrazolone derivatives |
| EP3515908A1 (en) | 2016-09-23 | 2019-07-31 | Syngenta Participations AG | Microbiocidal oxadiazole derivatives |
| US10653146B2 (en) | 2016-10-06 | 2020-05-19 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| UY37623A (es) | 2017-03-03 | 2018-09-28 | Syngenta Participations Ag | Derivados de oxadiazol tiofeno fungicidas |
| WO2018162643A1 (en) | 2017-03-10 | 2018-09-13 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| BR112019020134B1 (pt) | 2017-03-31 | 2023-05-09 | Syngenta Participations Ag | Composições fungicidas |
| CN110461159B (zh) | 2017-03-31 | 2022-03-11 | 先正达参股股份有限公司 | 杀真菌组合物 |
| US20210101874A1 (en) | 2017-04-03 | 2021-04-08 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| WO2018184987A1 (en) | 2017-04-05 | 2018-10-11 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| BR112019020739B1 (pt) | 2017-04-05 | 2023-12-19 | Syngenta Participations Ag | Compostos derivados de oxadiazol microbiocidas e seu uso, composição agroquímica, método para controlar ou prevenir a infestação de plantas úteis por microrganismos fitopatogênicos |
| WO2018184982A1 (en) | 2017-04-05 | 2018-10-11 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| WO2018184984A1 (en) | 2017-04-05 | 2018-10-11 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| WO2018184988A1 (en) | 2017-04-05 | 2018-10-11 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| BR112019020734B1 (pt) | 2017-04-05 | 2023-12-05 | Syngenta Participations Ag | Compostos derivados de oxadiazol, composição agroquímica, método para controlar ou prevenir a infestação de plantas úteis por microrganismos fitopatogênicos e uso dos referidos compostos |
| WO2018185211A1 (en) | 2017-04-06 | 2018-10-11 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| CN107094788A (zh) * | 2017-04-26 | 2017-08-29 | 深圳诺普信农化股份有限公司 | 杀菌组合物 |
| US11447481B2 (en) | 2017-06-02 | 2022-09-20 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| WO2018219773A1 (en) | 2017-06-02 | 2018-12-06 | Syngenta Participations Ag | Fungicidal compositions |
| US20200315176A1 (en) | 2017-06-28 | 2020-10-08 | Syngenta Participations Ag | Fungicidal compositions |
| WO2019011923A1 (en) | 2017-07-11 | 2019-01-17 | Syngenta Participations Ag | MICROBIOCIDE OXADIAZOLE DERIVATIVES |
| WO2019011928A1 (en) | 2017-07-11 | 2019-01-17 | Syngenta Participations Ag | MICROBIOCIDE OXADIAZOLE DERIVATIVES |
| WO2019011926A1 (en) | 2017-07-11 | 2019-01-17 | Syngenta Participations Ag | MICROBIOCIDE OXADIAZOLE DERIVATIVES |
| WO2019011929A1 (en) | 2017-07-11 | 2019-01-17 | Syngenta Participations Ag | MICROBIOCIDE OXADIAZOLE DERIVATIVES |
| BR112020000371A2 (pt) | 2017-07-12 | 2020-07-14 | Syngenta Participations Ag | derivados de oxadiazol microbiocidas |
| BR112020000414A2 (pt) | 2017-07-12 | 2020-07-21 | Syngenta Participations Ag | derivados de oxadiazol microbicidas |
| WO2019012003A1 (en) | 2017-07-13 | 2019-01-17 | Syngenta Participations Ag | MICROBIOCIDE OXADIAZOLE DERIVATIVES |
| CN111094248A (zh) | 2017-09-13 | 2020-05-01 | 先正达参股股份有限公司 | 杀微生物的喹啉(硫代)羧酰胺衍生物 |
| JP7202367B2 (ja) | 2017-09-13 | 2023-01-11 | シンジェンタ パーティシペーションズ アーゲー | 殺微生物性キノリン（チオ）カルボキサミド誘導体 |
| ES2904910T3 (es) | 2017-09-13 | 2022-04-06 | Syngenta Participations Ag | Derivados de quinolina (tio)carboxamida microbiocidas |
| JP7158468B2 (ja) | 2017-09-13 | 2022-10-21 | シンジェンタ パーティシペーションズ アーゲー | 殺微生物性キノリン（チオ）カルボキサミド誘導体 |
| CN111148736A (zh) | 2017-09-13 | 2020-05-12 | 先正达参股股份有限公司 | 杀微生物的喹啉（硫代）甲酰胺衍生物 |
| EP3681869B1 (en) | 2017-09-13 | 2021-12-08 | Syngenta Participations AG | Microbiocidal quinoline (thio)carboxamide derivatives |
| US11185074B2 (en) | 2017-09-13 | 2021-11-30 | Syngenta Participations Ag | Microbiocidal quinoline (thio)carboxamide derivatives |
| UY37913A (es) | 2017-10-05 | 2019-05-31 | Syngenta Participations Ag | Derivados de picolinamida fungicidas que portan un grupo terminal cuaternario |
| UY37912A (es) | 2017-10-05 | 2019-05-31 | Syngenta Participations Ag | Derivados de picolinamida fungicidas que portan grupos terminales heteroarilo o heteroariloxi |
| BR112020009659A2 (pt) | 2017-11-15 | 2020-11-10 | Syngenta Participations Ag | derivados picolinamida microbiocidas |
| WO2019097054A1 (en) | 2017-11-20 | 2019-05-23 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| AU2018376161B2 (en) | 2017-11-29 | 2023-07-13 | Syngenta Participations Ag | Microbiocidal thiazole derivatives |
| CN111566087A (zh) | 2017-12-19 | 2020-08-21 | 先正达参股股份有限公司 | 杀微生物的吡啶甲酰胺衍生物 |
| WO2019207062A1 (en) | 2018-04-26 | 2019-10-31 | Syngenta Participations Ag | Microbiocidal oxadiazole derivatives |
| US20210269426A1 (en) | 2018-06-29 | 2021-09-02 | Syngenta Crop Protection Ag | Microbiocidal oxadiazole derivatives |
| BR112020027003A2 (pt) | 2018-07-02 | 2021-04-06 | Syngenta Crop Protection Ag | Derivados de 3-(2-tienil)-5-(trifluorometil)-1,2,4-oxadiazol como fungicidas agroquímicos |
| WO2020016180A1 (en) | 2018-07-16 | 2020-01-23 | Syngenta Crop Protection Ag | Microbiocidal oxadiazole derivatives |
| JP2022501353A (ja) | 2018-09-19 | 2022-01-06 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 殺微生物性キノリンカルボキサミド誘導体 |
| JP2022502390A (ja) | 2018-09-26 | 2022-01-11 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 殺菌・殺カビ性組成物 |
| EP3860993B1 (en) | 2018-10-06 | 2022-08-10 | Syngenta Participations Ag | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives |
| WO2020070132A1 (en) | 2018-10-06 | 2020-04-09 | Syngenta Participations Ag | Microbiocidal quinoline dihydro-(thiazine)oxazine derivatives |
| TW202035404A (zh) | 2018-10-24 | 2020-10-01 | 瑞士商先正達農作物保護公司 | 具有含亞碸亞胺的取代基之殺有害生物活性雜環衍生物 |
| WO2020141136A1 (en) | 2018-12-31 | 2020-07-09 | Syngenta Crop Protection Ag | Pesticidally active heterocyclic derivatives with sulfur containing substituents |
| WO2020141135A1 (en) | 2018-12-31 | 2020-07-09 | Syngenta Crop Protection Ag | Pesticidally active heterocyclic derivatives with sulfur containing substituents |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2152396T3 (es) * | 1994-04-06 | 2001-02-01 | Shionogi & Co | Derivado del acido fenilacetico con sustitucion en gamma, su procedimiento de obtencion y bactericida agricola que lo contiene. |
| EP0781266A1 (de) * | 1994-09-10 | 1997-07-02 | Basf Aktiengesellschaft | Phenylessigsäurealkylester |
| JPH0995462A (ja) * | 1995-09-29 | 1997-04-08 | Shionogi & Co Ltd | α−ヒドロキシフェニル酢酸誘導体の製法 |
| JPH09227487A (ja) * | 1996-02-21 | 1997-09-02 | Agro Kanesho Co Ltd | オキシムエーテルを有するベンジルオキシベンゼン誘導体及びこれを有効成分とする農園芸用殺菌剤 |
| AU2001276690A1 (en) * | 2000-08-01 | 2002-02-13 | Shionogi And Co., Ltd. | Process for producing alcohol with transition metal complex having amide compound as ligand |
| JP2003026640A (ja) * | 2001-07-13 | 2003-01-29 | Shionogi & Co Ltd | 芳香族ケトンの製造方法 |
| TW200529812A (en) * | 2003-12-26 | 2005-09-16 | Chugai Pharmaceutical Co Ltd | Benzamide derivatives |
| JP4912314B2 (ja) * | 2004-10-26 | 2012-04-11 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 因子Ｘａ化合物 |
| ES2607404T3 (es) * | 2009-02-16 | 2017-03-31 | Sumitomo Chemical Company, Limited | Método para la producción de compuesto de fenilacetamida |
-
2010
- 2010-02-12 ES ES13178854.9T patent/ES2607404T3/es active Active
- 2010-02-12 EP EP13178854.9A patent/EP2662352B1/en active Active
- 2010-02-12 AU AU2010214305A patent/AU2010214305B2/en active Active
- 2010-02-12 PL PL13178853T patent/PL2682382T3/pl unknown
- 2010-02-12 LT LTEP13178853.1T patent/LT2682382T/lt unknown
- 2010-02-12 KR KR1020117020722A patent/KR101718173B1/ko active IP Right Grant
- 2010-02-12 TW TW105110299A patent/TWI570098B/zh active
- 2010-02-12 CN CN201310576643.6A patent/CN103641731B/zh active Active
- 2010-02-12 HU HUE13178853A patent/HUE031434T2/en unknown
- 2010-02-12 ES ES10741332.0T patent/ES2561845T3/es active Active
- 2010-02-12 WO PCT/JP2010/052486 patent/WO2010093059A1/ja active Application Filing
- 2010-02-12 US US13/147,823 patent/US8624062B2/en active Active
- 2010-02-12 KR KR1020167034930A patent/KR101808479B1/ko active IP Right Grant
- 2010-02-12 TW TW099104740A patent/TWI551576B/zh active
- 2010-02-12 CN CN201310576651.0A patent/CN103588657B/zh active Active
- 2010-02-12 EP EP10741332.0A patent/EP2397459B1/en active Active
- 2010-02-12 PL PL10741332T patent/PL2397459T3/pl unknown
- 2010-02-12 ES ES13178853.1T patent/ES2606916T3/es active Active
- 2010-02-12 EP EP13178853.1A patent/EP2682382B1/en active Active
- 2010-02-12 DK DK13178853.1T patent/DK2682382T3/da active
- 2010-02-12 DK DK10741332.0T patent/DK2397459T3/da active
- 2010-02-12 CN CN2010800116915A patent/CN102348677A/zh active Pending
- 2010-02-12 HU HUE10741332A patent/HUE027722T2/en unknown
- 2010-02-12 DK DK13178854.9T patent/DK2662352T3/da active
- 2010-02-16 JP JP2010031080A patent/JP5703568B2/ja active Active
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2011
- 2011-08-04 IL IL214470A patent/IL214470A/en active IP Right Grant
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- 2013-10-28 IL IL229117A patent/IL229117A/en active IP Right Grant
- 2013-10-28 IL IL229118A patent/IL229118A0/en active IP Right Grant
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2014
- 2014-11-17 JP JP2014232430A patent/JP5983710B2/ja active Active
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