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DK221589D0 - Fremgangsmaade til at udtrykke ikke-gaerprotein i en gaervaert og transformeret gaervaert - Google Patents

Fremgangsmaade til at udtrykke ikke-gaerprotein i en gaervaert og transformeret gaervaert

Info

Publication number
DK221589D0
DK221589D0 DK221589A DK221589A DK221589D0 DK 221589 D0 DK221589 D0 DK 221589D0 DK 221589 A DK221589 A DK 221589A DK 221589 A DK221589 A DK 221589A DK 221589 D0 DK221589 D0 DK 221589D0
Authority
DK
Denmark
Prior art keywords
gervair
transformed
procedure
expressing non
yellow protein
Prior art date
Application number
DK221589A
Other languages
English (en)
Other versions
DK221589A (da
DK175898B1 (da
Inventor
Jeffrey R Shuster
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DK221589D0 publication Critical patent/DK221589D0/da
Publication of DK221589A publication Critical patent/DK221589A/da
Application granted granted Critical
Publication of DK175898B1 publication Critical patent/DK175898B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • C07K14/503Fibroblast growth factor [FGF] basic FGF [bFGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK198902215A 1988-05-06 1989-05-05 Fremgangsmåde til at udtrykke ikke-gærprotein i en gærvært og transformeret gærvært samt anvendelsen af en transformeret gær til fremstilling af gærværten DK175898B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19086888A 1988-05-06 1988-05-06
US19086888 1988-05-06

Publications (3)

Publication Number Publication Date
DK221589D0 true DK221589D0 (da) 1989-05-05
DK221589A DK221589A (da) 1989-11-07
DK175898B1 DK175898B1 (da) 2005-05-30

Family

ID=22703135

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198902215A DK175898B1 (da) 1988-05-06 1989-05-05 Fremgangsmåde til at udtrykke ikke-gærprotein i en gærvært og transformeret gærvært samt anvendelsen af en transformeret gær til fremstilling af gærværten

Country Status (8)

Country Link
US (1) US6183985B1 (da)
EP (1) EP0340986B1 (da)
JP (4) JP3074174B2 (da)
AT (1) ATE123521T1 (da)
CA (1) CA1324969C (da)
DE (1) DE68922932T2 (da)
DK (1) DK175898B1 (da)
ES (1) ES2072900T3 (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0801682T3 (da) 1995-02-09 2002-02-18 Aventis Pharma Gmbh Fremgangsmåde til fremstilling af proteiner
DE19544233A1 (de) * 1995-11-28 1997-06-05 Hoechst Ag Verfahren zur Nutzung des Hefe-ADH II-Promotorsystems zur biotechnologischen Produktion heterologer Proteine in hohen Ausbeuten
DE60234854D1 (de) * 2001-09-20 2010-02-04 Toyota Motor Co Ltd Genüberexpressionssystem
NZ548256A (en) * 2004-02-02 2010-02-26 Ambrx Inc Modified human four helical bundle polypeptides and their uses
CN102532321B (zh) * 2004-06-18 2018-10-12 Ambrx公司 新颖抗原结合多肽和其用途
WO2006091231A2 (en) * 2004-07-21 2006-08-31 Ambrx, Inc. Biosynthetic polypeptides utilizing non-naturally encoded amino acids
CA2590462C (en) * 2004-12-22 2017-02-28 Ambrx, Inc. Methods for expression and purification of recombinant human growth hormone
CA3005835C (en) 2004-12-22 2023-01-31 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
CA2594557C (en) 2004-12-22 2016-04-26 Ambrx, Inc. Modified human growth hormone
ATE541934T1 (de) * 2004-12-22 2012-02-15 Ambrx Inc Zusammensetzungen von aminoacyl-trna-synthetase und verwendungen davon
SG161209A1 (en) 2004-12-22 2010-05-27 Ambrx Inc Formulations of human growth hormone comprising a non-naturally encoded amino acid
CN101247821B (zh) * 2005-06-03 2013-01-23 Ambrx公司 经改良人类干扰素分子和其用途
DE102005029170A1 (de) * 2005-06-23 2006-12-28 Consortium für elektrochemische Industrie GmbH System zur Genexpression in Hefen der Gattung Sporidiobolus
CN102703446B (zh) 2005-08-18 2014-05-28 Ambrx公司 tRNA组合物和其用途
RS51998B (en) * 2005-11-08 2012-04-30 Ambrx Inc. ACCELERATORS FOR MODIFICATION OF NON-NATURAL AMINO ACIDS AND NON-NATURAL AMINO ACID POLYPEPTIDES
AU2006315347A1 (en) 2005-11-16 2007-05-24 Ambrx, Inc. Methods and compositions comprising non-natural amino acids
WO2007081447A2 (en) 2005-11-22 2007-07-19 Novartis Vaccines And Diagnostics, Inc. Norovirus and sapovirus antigens
US8618257B2 (en) * 2006-09-08 2013-12-31 Ambrx, Inc. Modified human plasma polypeptide or Fc scaffolds and their uses
DK2061878T3 (da) * 2006-09-08 2014-04-07 Ambrx Inc Hybridsuppressor-trna for hvirveldyrceller
CA2662755C (en) * 2006-09-08 2017-04-04 Ambrx, Inc. Suppressor trna transcription in vertebrate cells
EP2106447B1 (en) * 2007-01-26 2013-04-17 Novozymes A/S Method for methanol independent induction from methanol inducible promoters in pichia
MX2009010531A (es) 2007-03-30 2009-11-26 Ambrx Inc Polipeptidos de fgf-21 modificados y usos de los mismos.
KR20100019467A (ko) 2007-05-02 2010-02-18 암브룩스, 인코포레이티드 변형된 인터페론 베타 폴리펩티드 및 그의 용도
MX338336B (es) 2007-11-20 2016-04-07 Ambrx Inc Polipeptidos de insulina modificados y sus usos.
EP2247743B1 (en) 2008-02-08 2016-04-06 Ambrx, Inc. Modified leptin polypeptides and their uses
WO2010004042A2 (en) * 2008-07-11 2010-01-14 Novozymes A/S Pichia pastoris das promoter variants
PL3225248T3 (pl) 2008-07-23 2023-11-27 Ambrx, Inc. Zmodyfikowane polipeptydy bydlęcego G-CSF i ich zastosowania
ES2631915T3 (es) 2008-09-26 2017-09-06 Ambrx, Inc. Polipéptidos modificados de eritropoyetina animal y sus usos
PE20110480A1 (es) 2008-09-26 2011-07-01 Ambrx Inc Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales
CA2784793A1 (en) 2009-12-21 2011-07-21 Ambrx, Inc. Modified bovine somatotropin polypeptides and their uses
MX2012006980A (es) 2009-12-21 2012-07-17 Ambrx Inc Polipeptidos de somatotropina porcina modificados y sus usos.
JP2013533745A (ja) 2010-07-06 2013-08-29 ノバルティス アーゲー ノロウイルスに由来する免疫原性組成物および方法
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
PT3572091T (pt) 2010-08-17 2024-03-01 Ambrx Inc Polipéptidos de relaxina modificados e as suas utilizações
AR083006A1 (es) 2010-09-23 2013-01-23 Lilly Co Eli Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
EP3412302B1 (en) 2014-10-24 2021-05-12 Bristol-Myers Squibb Company Modified fgf-21 polypeptides and uses thereof
MX2019008449A (es) 2017-02-08 2019-09-09 Bristol Myers Squibb Co Polipetidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880734A (en) * 1984-05-11 1989-11-14 Chiron Corporation Eukaryotic regulatable transcription
EP0196056B1 (en) * 1985-03-28 1991-05-22 Chiron Corporation Improved expression using fused genes providing for protein product
EP0234871A3 (en) 1986-02-28 1988-10-12 Merck & Co. Inc. Regulatable expression of recombinant proteins in yeast
US5068185A (en) 1986-07-10 1991-11-26 Merck & Co., Inc. Trains of yeast for the expression of heterologous genes

Also Published As

Publication number Publication date
DE68922932D1 (de) 1995-07-13
EP0340986A2 (en) 1989-11-08
US6183985B1 (en) 2001-02-06
JP3484386B2 (ja) 2004-01-06
CA1324969C (en) 1993-12-07
JP2000300277A (ja) 2000-10-31
ATE123521T1 (de) 1995-06-15
ES2072900T3 (es) 1995-08-01
DE68922932T2 (de) 1995-10-19
JPH02104291A (ja) 1990-04-17
JP3561513B2 (ja) 2004-09-02
EP0340986B1 (en) 1995-06-07
DK221589A (da) 1989-11-07
JP3074174B2 (ja) 2000-08-07
EP0340986A3 (en) 1991-07-31
JP2004081222A (ja) 2004-03-18
JP2003116525A (ja) 2003-04-22
DK175898B1 (da) 2005-05-30

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