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DK175582B1 - Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion - Google Patents

Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion Download PDF

Info

Publication number
DK175582B1
DK175582B1 DK198802081A DK208188A DK175582B1 DK 175582 B1 DK175582 B1 DK 175582B1 DK 198802081 A DK198802081 A DK 198802081A DK 208188 A DK208188 A DK 208188A DK 175582 B1 DK175582 B1 DK 175582B1
Authority
DK
Denmark
Prior art keywords
compound
hiv
cells
infection
prophylaxis
Prior art date
Application number
DK198802081A
Other languages
Danish (da)
English (en)
Other versions
DK208188A (da
DK208188D0 (da
Inventor
Patrick Thomas Prendergast
Original Assignee
Patrick Thomas Prendergast
Colthurst Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Patrick Thomas Prendergast, Colthurst Ltd filed Critical Patrick Thomas Prendergast
Publication of DK208188D0 publication Critical patent/DK208188D0/da
Publication of DK208188A publication Critical patent/DK208188A/da
Application granted granted Critical
Publication of DK175582B1 publication Critical patent/DK175582B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK198802081A 1987-04-16 1988-04-15 Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion DK175582B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IE99787 1987-04-16
IE99787 1987-04-16
IE228987 1987-08-27
IE228987 1987-08-27

Publications (3)

Publication Number Publication Date
DK208188D0 DK208188D0 (da) 1988-04-15
DK208188A DK208188A (da) 1988-10-17
DK175582B1 true DK175582B1 (da) 2004-12-13

Family

ID=26319024

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198802081A DK175582B1 (da) 1987-04-16 1988-04-15 Anvendelse af en 17-ketosteroid forbindelse til brug ved profylakse og behandling af retroviral infektion

Country Status (23)

Country Link
US (1) US4956355A (de)
JP (1) JP2577771B2 (de)
KR (1) KR960014988B1 (de)
AT (1) AT401470B (de)
AU (1) AU608824B2 (de)
BE (1) BE1004315A5 (de)
CA (1) CA1325594C (de)
CH (1) CH675358A5 (de)
DE (1) DE3812595C2 (de)
DK (1) DK175582B1 (de)
FI (1) FI881773A (de)
FR (1) FR2615394B1 (de)
GB (1) GB2204237B (de)
GR (1) GR1002240B (de)
IL (1) IL86089A (de)
IT (1) IT1227073B (de)
LU (1) LU87202A1 (de)
NL (1) NL194728C (de)
NZ (1) NZ224272A (de)
OA (1) OA08729A (de)
PH (1) PH25907A (de)
PT (1) PT87259B (de)
SE (1) SE503482C2 (de)

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US6638894B1 (en) * 1987-01-09 2003-10-28 Lucent Technologies Inc. Devices and systems based on novel superconducting material
EP0309519B1 (de) * 1987-04-09 1992-07-08 FISONS plc Pentamidin enthaltende pharmazeutische zusammensetzungen
US5204113A (en) * 1987-04-09 1993-04-20 Fisons Plc Pharmaceutical compositions containing pentamidine
US5407684A (en) * 1988-12-30 1995-04-18 Virginia Commonwealth University Use of DHEA as a medicinal
US5077284A (en) * 1988-12-30 1991-12-31 Loria Roger M Use of dehydroepiandrosterone to improve immune response
CA2066716A1 (en) * 1989-09-25 1991-03-26 Raymond A. Daynes Use of steroid hormones in compositions for inducing t cell lymphokine production
US5919465A (en) * 1989-09-25 1999-07-06 University Of Utah Research Foundation Methods for augmenting immunological responses through the administration of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone-sulfate (DHEA-S)
US5824313A (en) * 1989-09-25 1998-10-20 University Of Utah Research Foundation Vaccine compositions and method for induction of mucosal immune response via systemic vaccination
US5518725A (en) * 1989-09-25 1996-05-21 University Of Utah Research Foundation Vaccine compositions and method for induction of mucosal immune response via systemic vaccination
US5837269A (en) * 1989-09-25 1998-11-17 University Of Utah Research Foundation Vaccine compositions and method for enhancing an immune response
US5562910A (en) * 1989-09-25 1996-10-08 University Of Utah Research Foundation Vaccine compositions and method for enhancing an immune response
US5162361A (en) * 1990-04-10 1992-11-10 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Method of treating diseases associated with elevated levels of interleukin 1
US5292730A (en) * 1990-08-29 1994-03-08 Humanetics Corporation Modulation of immune system with Δ5-androstenes
IE63418B1 (en) * 1990-09-10 1995-04-19 Elan Corp Plc Progression risk of HIV by assay of dehydroepiandrosterone in body fluid
US5206008A (en) * 1991-04-15 1993-04-27 Virginia Commonwealth University Enhancement of immune response
JPH05317041A (ja) * 1991-06-05 1993-12-03 Nippon Oil Co Ltd 動物細胞増殖促進剤及び無血清培地
US5230897A (en) * 1991-10-31 1993-07-27 G. D. Searle & Co. Transdermal pentamidine
EP0627921B1 (de) * 1992-02-24 2000-05-31 East Carolina University Verfahren zur hemmung der karzinogenese durch behandlung mit dehydroepiandrosteron und dessen analoge
NZ252491A (en) * 1992-05-01 1997-05-26 Univ Utah Compositions of dhea (dehydroepiandrosterone) congeners to treat abnormally elevated il-6 levels
US5346997A (en) * 1992-08-26 1994-09-13 Murphy James G Agents for complexing sodium under biological conditions
FR2696934B1 (fr) * 1992-10-20 1995-06-02 Conservatoire Nal Arts Metiers Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir.
US5776923A (en) * 1993-01-19 1998-07-07 Endorecherche, Inc. Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone
CN1100541C (zh) * 1993-01-19 2003-02-05 恩多研究公司 脱氢表雄酮的治疗用途和传送系统
US5439899A (en) * 1993-03-10 1995-08-08 Purdue Research Foundation Cosalane and related compounds having activity against aids and aids-related infections
US5407927A (en) * 1993-04-16 1995-04-18 The Regents Of The University Of California Treatment of mild depression and restoration of IGF-I levels in aging by dehydroepiandrosterone
US5466465A (en) * 1993-12-30 1995-11-14 Harrogate Holdings, Limited Transdermal drug delivery system
ATE412769T1 (de) * 1994-04-05 2008-11-15 Morre D James Nadh-oxidase als zielmolekül in diagnose und therapie
US20020032160A1 (en) * 1995-02-24 2002-03-14 Nyce Jonathan W. Compositions & formulations with an epiandrosterone or a ubiquinone & kits & their use for treatment of asthma symptoms & for reducing adenosine/adenosine receptor levels
US5660835A (en) * 1995-02-24 1997-08-26 East Carolina University Method of treating adenosine depletion
US7893044B2 (en) * 1995-02-24 2011-02-22 Epigenesis Pharmaceutical, Inc. Composition and method for altering levels of or sensitivity to adenosine with analogs of dehydroepiandrosterone
CA2244535A1 (en) * 1995-05-15 2000-01-30 Avon Products, Inc. Novel uses for ascorbyl-phosphoryl-cholesterol in topical compositions
US6162450A (en) * 1995-05-15 2000-12-19 Avon Products, Inc. Uses of ascorbyl-phosphoryl-cholesterol and compositions for practicing same
US5736537A (en) 1995-09-12 1998-04-07 Estee Lauder, Inc. Dehydroep:androsterone sailcylate useful against skin atrophy
BR9608158A (pt) * 1996-05-14 1999-02-09 Avon Prod Inc Ascorbil-fosforil-colesterol
GB9612990D0 (en) * 1996-06-20 1996-08-21 Stanford Rock Ltd Compositions and methods for the treatment of chronic infections
US5885977A (en) * 1997-01-15 1999-03-23 Humanetics Corporation Use of Δ5 androstenes in the treatment of HIV wasting syndrome
US5902593A (en) * 1997-10-01 1999-05-11 Kent; Frances B. Topically applied personal lubricant containing benzalkonium chloride as the active ingredient
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
US20070129282A1 (en) * 1998-11-24 2007-06-07 Ahlem Clarence N Pharmaceutical treatments and compositions
KR20070004149A (ko) * 1998-11-24 2007-01-05 홀리스-에덴 파마슈티칼즈, 인코포레이티드 17-케토스테로이드 화합물
US20060079492A1 (en) * 1999-10-25 2006-04-13 Ahlem Clarence N Compositions and treatment methods
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
AU775614B2 (en) * 1998-11-24 2004-08-05 Harbor Biosciences, Inc. Use of 17-ketosteroid compounds and derivatives, metabolites and precursors thereof in the treatment of hepatitis C virus and other togaviruses
WO2000032176A2 (en) * 1998-11-27 2000-06-08 Hollis-Eden Pharmaceuticals, Inc. Use of 17-ketosteroids for the treatment of toxoplasmosis and cryptosporidosis
EP1422234A3 (de) * 1999-03-23 2010-12-08 Harbor BioSciences, Inc. Immunomodulierende Steroide, Insbesondere Die Hemihydrat Von 16.alpha.-bromoepiandrosteronen
AP2001002285A0 (en) * 1999-03-23 2001-12-31 Hollis Eden Pharmaceuticals Inc Immunomodulatory steroids, in particular the hemihydrate of. 16 alpha.-bromoepiandrosterone.
FR2792201B1 (fr) * 1999-04-15 2001-11-02 Donatien Mavoungou Procede du renforcement immunitaire et du developpement d'un transporteur lipidique pour une therapie genique anti-vih et anti-bacterienne
US7479498B2 (en) * 1999-08-23 2009-01-20 Phoenix Biosciences, Inc. Treatments for viral infections
US20050245502A1 (en) * 1999-08-23 2005-11-03 Phoenix Biosciences Treatments for viral infections
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WO2002085296A2 (en) * 2001-04-24 2002-10-31 Epigenesis Pharmaceuticals, Inc. Composition, formulations and kit for treatment of respiratory and lung disease with non-glucocorticoid steroids and/or ubiquinone and a bronchodilating agent
EP1553954A4 (de) * 2002-06-17 2009-12-23 Epigenesis Pharmaceuticals Llc Dihydrat-dehydroepiandrosteron und verfahren zur behandlung von asthma oder chronisch obstruktiver lungenerkrankung mit zusammensetzungen daraus
US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
US20050026881A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anti-IgE antibody for treatment of asthma or chronic obstructive pulmonary disease
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US20090297611A1 (en) * 2003-07-31 2009-12-03 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a tyrosine kinase inhibitor, delta opioid receptor antagonist, neurokinin receptor antagonist, or vcam inhibitor for treatment of asthma or chronic obstructive pulmonary disease
US20050026848A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a methylxanthine derivative for treatment of asthma or chronic obstructive pulmonary disease
US20050026882A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20050113318A1 (en) * 2003-07-31 2005-05-26 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20050026880A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a cromone for treatment of asthma or chronic obstructive pulmonary disease
US20050101545A1 (en) * 2003-07-31 2005-05-12 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20050043282A1 (en) * 2003-07-31 2005-02-24 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a lipoxygenase inhibitor for treatment of asthma or chronic obstructive pulmonary disease
US20090263381A1 (en) * 2003-07-31 2009-10-22 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anti-ige antibody for treatment of asthma or chronic obstructive pulmonary disease
US20090317476A1 (en) * 2003-07-31 2009-12-24 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
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Also Published As

Publication number Publication date
AU608824B2 (en) 1991-04-18
DE3812595A1 (de) 1988-10-27
NL194728C (nl) 2003-01-07
IT1227073B (it) 1991-03-14
AT401470B (de) 1996-09-25
FI881773A (fi) 1988-10-17
KR960014988B1 (ko) 1996-10-23
GB2204237B (en) 1991-02-06
DE3812595C2 (de) 1997-07-03
JPS6425722A (en) 1989-01-27
BE1004315A5 (fr) 1992-11-03
US4956355A (en) 1990-09-11
NL194728B (nl) 2002-09-02
SE8801406D0 (sv) 1988-04-15
NL8800926A (nl) 1988-11-16
JP2577771B2 (ja) 1997-02-05
PT87259B (pt) 1992-08-31
CH675358A5 (de) 1990-09-28
FR2615394B1 (fr) 1994-09-23
GR1002240B (en) 1996-04-22
GB8808864D0 (en) 1988-05-18
LU87202A1 (fr) 1988-11-17
CA1325594C (en) 1993-12-28
PH25907A (en) 1991-12-19
SE8801406L (sv) 1988-10-17
IL86089A0 (en) 1988-09-30
NZ224272A (en) 1991-09-25
ATA98488A (de) 1996-02-15
SE503482C2 (sv) 1996-06-24
GR880100248A (el) 1989-01-31
DK208188A (da) 1988-10-17
IT8847858A0 (it) 1988-04-15
KR880012233A (ko) 1988-11-26
PT87259A (pt) 1988-05-01
AU1467888A (en) 1988-10-20
OA08729A (en) 1989-03-31
DK208188D0 (da) 1988-04-15
FI881773A0 (fi) 1988-04-15
FR2615394A1 (fr) 1988-11-25
GB2204237A (en) 1988-11-09
IL86089A (en) 1992-11-15

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