DK1491212T3 - Middel til behandling af søvnforstyrrelser - Google Patents
Middel til behandling af søvnforstyrrelserInfo
- Publication number
- DK1491212T3 DK1491212T3 DK03715566.0T DK03715566T DK1491212T3 DK 1491212 T3 DK1491212 T3 DK 1491212T3 DK 03715566 T DK03715566 T DK 03715566T DK 1491212 T3 DK1491212 T3 DK 1491212T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- sleep disorders
- sleep
- disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/527—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002093398 | 2002-03-29 | ||
PCT/JP2003/003925 WO2003082333A1 (fr) | 2002-03-29 | 2003-03-28 | Remede contre les troubles du sommeil |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1491212T3 true DK1491212T3 (da) | 2012-10-29 |
Family
ID=28671758
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03715566.0T DK1491212T3 (da) | 2002-03-29 | 2003-03-28 | Middel til behandling af søvnforstyrrelser |
Country Status (8)
Country | Link |
---|---|
US (2) | US7566728B2 (da) |
EP (1) | EP1491212B1 (da) |
JP (1) | JP4056977B2 (da) |
AU (1) | AU2003220886A1 (da) |
DK (1) | DK1491212T3 (da) |
ES (1) | ES2392340T3 (da) |
PT (1) | PT1491212E (da) |
WO (1) | WO2003082333A1 (da) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006025267A1 (ja) * | 2004-08-31 | 2006-03-09 | Mitsubishi Pharma Corporation | Per2タンパク質レベルの低下を作用機序とする睡眠障害治療薬 |
JP5209481B2 (ja) | 2005-09-30 | 2013-06-12 | グラクソ グループ リミテッド | M1受容体にて活性を有する化合物および医薬におけるそれらの使用 |
JP5209480B2 (ja) | 2005-09-30 | 2013-06-12 | グラクソ グループ リミテッド | M1受容体にて活性を有する化合物および医薬におけるそれらの使用 |
EP1937670A1 (en) | 2005-09-30 | 2008-07-02 | Glaxo Group Limited | Benzimidazolones which have activity at m1 receptor |
GB0605784D0 (en) * | 2006-03-22 | 2006-05-03 | Glaxo Group Ltd | Compounds |
CA2666630C (en) * | 2006-10-16 | 2012-01-24 | Mitsubishi Tanabe Pharma Corporation | Agent for prophylaxis or treatment of alcohol dependence or drug dependence |
JPWO2008102859A1 (ja) * | 2007-02-22 | 2010-05-27 | 田辺三菱製薬株式会社 | 不安障害の予防および/または治療薬 |
US8877779B2 (en) | 2007-03-01 | 2014-11-04 | Mitsubishi Tanabe Pharma Corporation | Benzimidazole compound and pharmaceutical use thereof |
RU2451017C2 (ru) * | 2007-03-01 | 2012-05-20 | Мицубиси Танабе Фарма Корпорейшн | Бензимидазольное соединение и его фармацевтическое применение |
RU2488585C2 (ru) * | 2007-08-31 | 2013-07-27 | Пэдью Фарма Л.П. | Замещенные пиперидиновые соединения хиноксалинового типа и их применение |
JP5416210B2 (ja) | 2008-07-21 | 2014-02-12 | パーデュー、ファーマ、リミテッド、パートナーシップ | 置換キノキサリンタイプ架橋ピペリジン化合物とその使用 |
TW201016675A (en) | 2008-09-16 | 2010-05-01 | Mitsubishi Tanabe Pharma Corp | Crystalline benzoimidazole compound and salt thereof |
WO2010090198A1 (ja) | 2009-02-03 | 2010-08-12 | 田辺三菱製薬株式会社 | 1-(4-ピペリジニル)ベンゾイミダゾロン誘導体の製造方法 |
US9963458B2 (en) | 2012-12-27 | 2018-05-08 | Purdue Pharma L.P. | Indole and indoline-type piperidine compounds and uses thereof |
WO2014102589A1 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Quinazolin-4(3h)-one-type piperidine compounds and uses thereof |
WO2014102594A2 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
US9040533B2 (en) | 2012-12-27 | 2015-05-26 | Purdue Pharma L.P. | Oxime-substituted-quinoxaline-type piperidine compounds as ORL-1 modulators |
WO2014102590A1 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Substituted piperidin-4-amino-type compounds and uses thereof |
CA2896871A1 (en) * | 2012-12-31 | 2014-07-03 | Kerry L. Spear | Heterocyclic compounds and methods of use thereof |
JOP20190008A1 (ar) * | 2016-07-26 | 2019-01-24 | Purdue Pharma Lp | علاج ومنع اضطرابات النوم |
CA3084035C (en) | 2018-01-24 | 2023-10-24 | Stephen C. Harris | Sleep disorder treatment and prevention |
CN117642389A (zh) * | 2021-07-14 | 2024-03-01 | 宜昌人福药业有限责任公司 | 一种哌啶衍生物及其药物组合物、制备方法和用途 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2226058C (en) | 1997-01-30 | 2008-01-29 | F. Hoffmann-La Roche Ag | 8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives |
CA2291094C (en) * | 1997-05-30 | 2008-02-26 | Banyu Pharmaceutical Co., Ltd. | 2-oxoimidazole derivative |
PT921125E (pt) * | 1997-12-05 | 2002-06-28 | Hoffmann La Roche | Derivados de 1,38-triaza-espiro 4,5 decan-4-ona |
US6166209A (en) * | 1997-12-11 | 2000-12-26 | Hoffmann-La Roche Inc. | Piperidine derivatives |
WO1999036421A1 (en) * | 1998-01-19 | 1999-07-22 | Pfizer Pharmaceuticals Inc. | 4-(2-keto-1-benzimidazolinyl)piperidine compounds as orl1-receptor agonists |
AU754716B2 (en) | 1998-03-26 | 2002-11-21 | Japan Tobacco Inc. | Amide derivatives and nociceptin antagonists |
KR100357541B1 (ko) | 1998-05-15 | 2002-10-18 | 주식회사종근당 | 5-데메톡시 푸마질롤 유도체 및 그 제조방법 |
AU3809999A (en) | 1998-05-18 | 1999-12-06 | Novo Nordisk A/S | Novel 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes |
US6277991B1 (en) * | 1998-05-18 | 2001-08-21 | Novo Nordisk A/S | 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes |
SI0970957T1 (da) * | 1998-06-12 | 2001-12-31 | Hoffmann La Roche | |
EP0963985B1 (en) * | 1998-06-12 | 2003-03-12 | F. Hoffmann-La Roche Ag | Di-or triaza-spiro(4,5)decane derivatives |
ID29137A (id) | 1998-07-27 | 2001-08-02 | Schering Corp | Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1 |
MA26659A1 (fr) * | 1998-08-06 | 2004-12-20 | Pfizer | Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation. |
JP2000053686A (ja) | 1998-08-12 | 2000-02-22 | Yushi Seihin Kk | フルオロアルキルアルコキシシラン及びその製造方法 |
CO5150201A1 (es) | 1998-09-07 | 2002-04-29 | Hoffmann La Roche | Derivados de piperidina |
EP0997464B1 (en) | 1998-10-23 | 2005-02-16 | Pfizer Inc. | 1,3,8-Triazaspiro[4,5] decanone compounds as orl1-receptor agonists |
IT1303737B1 (it) | 1998-11-11 | 2001-02-23 | Smithkline Beecham Spa | Derivati fenilpiperidinici procedimento per la loro preparazione eloro uso come ligandi del recettore orl-1. |
AU1185300A (en) | 1998-11-20 | 2000-06-13 | Banyu Pharmaceutical Co., Ltd. | 2-oxoimidazole derivatives |
US6340681B1 (en) | 1999-07-16 | 2002-01-22 | Pfizer Inc | 2-benzimidazolylamine compounds as ORL-1-receptor agonists |
JP2001058991A (ja) | 1999-08-20 | 2001-03-06 | Banyu Pharmaceut Co Ltd | スルホンアミド誘導体 |
EP1222185A1 (en) * | 1999-10-18 | 2002-07-17 | Smithkline Beecham Plc | Tetrahydrobenzindolone derivatives, their preparation and their use as 5-ht7 receptor antagonists |
EP1244437A4 (en) * | 1999-12-06 | 2005-02-09 | Euro Celtique Sa | TERTIARY AMINO COMPOUNDS HAVING AFFINITY FOR OPIOID RECEPTOR |
WO2001039775A1 (en) | 1999-12-06 | 2001-06-07 | Euro-Celtique, S.A. | Benzimidazole compounds having nociceptin receptor affinity |
DE60023100T2 (de) * | 2000-01-05 | 2006-07-06 | Pfizer Inc. | Benzimidazol-Verbindungen zur Verwendung als ORL1-Rezeptor-Antagonisten |
AU2001283955B2 (en) * | 2000-07-31 | 2006-05-18 | F. Hoffmann-La Roche Ag | Piperazine derivatives |
WO2002026714A1 (fr) | 2000-09-27 | 2002-04-04 | Takeda Chemical Industries, Ltd. | Composes spiraniques |
MXPA03009602A (es) | 2001-04-18 | 2004-04-02 | Euro Celtique Sa | Analogos de nociceptina. |
EP2033644A1 (en) * | 2001-04-18 | 2009-03-11 | Euro-Celtique S.A. | Spiroindene and spiroindane compounds |
PL367263A1 (en) | 2001-04-18 | 2005-02-21 | Euro-Celtique, S.A. | Spiropyrazole compounds |
ATE456564T1 (de) | 2001-04-18 | 2010-02-15 | Euro Celtique Sa | Octahydrobenzimidazolon-verbindungen als analgetika |
US20030078278A1 (en) * | 2001-06-26 | 2003-04-24 | Pfizer Inc. | Spiropiperidine compounds as ligands for ORL-1 receptor |
DE60226874D1 (de) * | 2001-07-23 | 2008-07-10 | Banyu Pharma Co Ltd | 4-oxoimidazolidin-2-spiro piperidin derivat |
-
2003
- 2003-03-28 US US10/508,339 patent/US7566728B2/en not_active Expired - Fee Related
- 2003-03-28 ES ES03715566T patent/ES2392340T3/es not_active Expired - Lifetime
- 2003-03-28 PT PT03715566T patent/PT1491212E/pt unknown
- 2003-03-28 AU AU2003220886A patent/AU2003220886A1/en not_active Abandoned
- 2003-03-28 WO PCT/JP2003/003925 patent/WO2003082333A1/ja active Application Filing
- 2003-03-28 JP JP2003579869A patent/JP4056977B2/ja not_active Expired - Fee Related
- 2003-03-28 EP EP03715566A patent/EP1491212B1/en not_active Expired - Lifetime
- 2003-03-28 DK DK03715566.0T patent/DK1491212T3/da active
-
2009
- 2009-04-28 US US12/453,057 patent/US8003669B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP4056977B2 (ja) | 2008-03-05 |
ES2392340T3 (es) | 2012-12-07 |
EP1491212A1 (en) | 2004-12-29 |
EP1491212B1 (en) | 2012-08-08 |
PT1491212E (pt) | 2012-11-16 |
EP1491212A4 (en) | 2009-10-28 |
US20090253747A1 (en) | 2009-10-08 |
US7566728B2 (en) | 2009-07-28 |
JPWO2003082333A1 (ja) | 2005-07-28 |
US20050119308A1 (en) | 2005-06-02 |
AU2003220886A1 (en) | 2003-10-13 |
US8003669B2 (en) | 2011-08-23 |
WO2003082333A1 (fr) | 2003-10-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1491212T3 (da) | Middel til behandling af søvnforstyrrelser | |
DK1474416T3 (da) | Dihydrobenzodiazepin-2-on-derivater til behandlingen af neurologiske lidelser | |
DK1803718T3 (da) | 4-Tetrazolyl-4-phenylpiperidin-derivater til behandling af smerter | |
DK1663978T3 (da) | Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser | |
IS7099A (is) | Efnasambönd til að meðhöndla bólgutruflanir | |
DK1660057T3 (da) | Kombinationsterapi til behandling af neovaskulære øjenlidelser | |
DK1343773T3 (da) | Thiazolderivater til behandling af PPAR-beslægtede forstyrrelser | |
DK1812110T3 (da) | Apparat til behandling af dermatologiske lidelser | |
DK2308507T3 (da) | Fremgangsmåder til behandling af præeklampsi | |
DK1701941T3 (da) | Forbindelser til behandling af sygdomme med celleproliferation | |
IS7738A (is) | Þíasól efnasambönd til notkunar í meðferð á taugahrörnunar truflunum. | |
DK1890684T3 (da) | Behandling af søvn/vågenhedsforstyrrelser | |
NO20053211D0 (no) | Forbindelser for behandling av metabolske forstyrrelser. | |
DK1575597T3 (da) | Anvendelse af rimexolon til behandling af öjentörhed | |
DK1708992T3 (da) | Sulfonamidderivater til behandling af sygdomme | |
DK1551860T3 (da) | Glukokortikoid-receptorligander til behandling af stofskifteforstyrrelser | |
DK1448205T3 (da) | Kombinationer til behandling af immunoinflammatoriske sygdomme | |
DK1499730T3 (da) | Immunokonjugater til behandling af tumorer | |
DE502004010131D1 (de) | Pyridopyrimidinone zur behandlung von krebserkrankungen | |
NO20045554L (no) | Fremgangsmate for behandling av diabetes | |
DK1841433T3 (da) | Præparat til behandling af lidelser i centralnervesystemet | |
ITMI20031311A0 (it) | Formulazioni per il trattamento di disturbi artrosici | |
DK1487828T3 (da) | Morpholinyl-urea-derivater til anvendelse til behandling af inflammatoriske sygdomme | |
DK1727801T3 (da) | Til behandling af smerter anvendelige piperaziner | |
NO20055098D0 (no) | Anvendelse av 10-hydroksy-10,11-dihydrokarbamazepinderivater for behandling av affektive forstyrrelser |