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DK1491212T3 - Middel til behandling af søvnforstyrrelser - Google Patents

Middel til behandling af søvnforstyrrelser

Info

Publication number
DK1491212T3
DK1491212T3 DK03715566.0T DK03715566T DK1491212T3 DK 1491212 T3 DK1491212 T3 DK 1491212T3 DK 03715566 T DK03715566 T DK 03715566T DK 1491212 T3 DK1491212 T3 DK 1491212T3
Authority
DK
Denmark
Prior art keywords
treatment
sleep disorders
sleep
disorders
Prior art date
Application number
DK03715566.0T
Other languages
English (en)
Inventor
Koji Teshima
Masanori Minoguchi
Original Assignee
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28671758&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1491212(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitsubishi Tanabe Pharma Corp filed Critical Mitsubishi Tanabe Pharma Corp
Application granted granted Critical
Publication of DK1491212T3 publication Critical patent/DK1491212T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/527Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK03715566.0T 2002-03-29 2003-03-28 Middel til behandling af søvnforstyrrelser DK1491212T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002093398 2002-03-29
PCT/JP2003/003925 WO2003082333A1 (fr) 2002-03-29 2003-03-28 Remede contre les troubles du sommeil

Publications (1)

Publication Number Publication Date
DK1491212T3 true DK1491212T3 (da) 2012-10-29

Family

ID=28671758

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03715566.0T DK1491212T3 (da) 2002-03-29 2003-03-28 Middel til behandling af søvnforstyrrelser

Country Status (8)

Country Link
US (2) US7566728B2 (da)
EP (1) EP1491212B1 (da)
JP (1) JP4056977B2 (da)
AU (1) AU2003220886A1 (da)
DK (1) DK1491212T3 (da)
ES (1) ES2392340T3 (da)
PT (1) PT1491212E (da)
WO (1) WO2003082333A1 (da)

Families Citing this family (22)

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WO2006025267A1 (ja) * 2004-08-31 2006-03-09 Mitsubishi Pharma Corporation Per2タンパク質レベルの低下を作用機序とする睡眠障害治療薬
JP5209481B2 (ja) 2005-09-30 2013-06-12 グラクソ グループ リミテッド M1受容体にて活性を有する化合物および医薬におけるそれらの使用
JP5209480B2 (ja) 2005-09-30 2013-06-12 グラクソ グループ リミテッド M1受容体にて活性を有する化合物および医薬におけるそれらの使用
EP1937670A1 (en) 2005-09-30 2008-07-02 Glaxo Group Limited Benzimidazolones which have activity at m1 receptor
GB0605784D0 (en) * 2006-03-22 2006-05-03 Glaxo Group Ltd Compounds
CA2666630C (en) * 2006-10-16 2012-01-24 Mitsubishi Tanabe Pharma Corporation Agent for prophylaxis or treatment of alcohol dependence or drug dependence
JPWO2008102859A1 (ja) * 2007-02-22 2010-05-27 田辺三菱製薬株式会社 不安障害の予防および/または治療薬
US8877779B2 (en) 2007-03-01 2014-11-04 Mitsubishi Tanabe Pharma Corporation Benzimidazole compound and pharmaceutical use thereof
RU2451017C2 (ru) * 2007-03-01 2012-05-20 Мицубиси Танабе Фарма Корпорейшн Бензимидазольное соединение и его фармацевтическое применение
RU2488585C2 (ru) * 2007-08-31 2013-07-27 Пэдью Фарма Л.П. Замещенные пиперидиновые соединения хиноксалинового типа и их применение
JP5416210B2 (ja) 2008-07-21 2014-02-12 パーデュー、ファーマ、リミテッド、パートナーシップ 置換キノキサリンタイプ架橋ピペリジン化合物とその使用
TW201016675A (en) 2008-09-16 2010-05-01 Mitsubishi Tanabe Pharma Corp Crystalline benzoimidazole compound and salt thereof
WO2010090198A1 (ja) 2009-02-03 2010-08-12 田辺三菱製薬株式会社 1-(4-ピペリジニル)ベンゾイミダゾロン誘導体の製造方法
US9963458B2 (en) 2012-12-27 2018-05-08 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
WO2014102589A1 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Quinazolin-4(3h)-one-type piperidine compounds and uses thereof
WO2014102594A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
US9040533B2 (en) 2012-12-27 2015-05-26 Purdue Pharma L.P. Oxime-substituted-quinoxaline-type piperidine compounds as ORL-1 modulators
WO2014102590A1 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
CA2896871A1 (en) * 2012-12-31 2014-07-03 Kerry L. Spear Heterocyclic compounds and methods of use thereof
JOP20190008A1 (ar) * 2016-07-26 2019-01-24 Purdue Pharma Lp علاج ومنع اضطرابات النوم
CA3084035C (en) 2018-01-24 2023-10-24 Stephen C. Harris Sleep disorder treatment and prevention
CN117642389A (zh) * 2021-07-14 2024-03-01 宜昌人福药业有限责任公司 一种哌啶衍生物及其药物组合物、制备方法和用途

Family Cites Families (32)

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CA2226058C (en) 1997-01-30 2008-01-29 F. Hoffmann-La Roche Ag 8-substituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives
CA2291094C (en) * 1997-05-30 2008-02-26 Banyu Pharmaceutical Co., Ltd. 2-oxoimidazole derivative
PT921125E (pt) * 1997-12-05 2002-06-28 Hoffmann La Roche Derivados de 1,38-triaza-espiro 4,5 decan-4-ona
US6166209A (en) * 1997-12-11 2000-12-26 Hoffmann-La Roche Inc. Piperidine derivatives
WO1999036421A1 (en) * 1998-01-19 1999-07-22 Pfizer Pharmaceuticals Inc. 4-(2-keto-1-benzimidazolinyl)piperidine compounds as orl1-receptor agonists
AU754716B2 (en) 1998-03-26 2002-11-21 Japan Tobacco Inc. Amide derivatives and nociceptin antagonists
KR100357541B1 (ko) 1998-05-15 2002-10-18 주식회사종근당 5-데메톡시 푸마질롤 유도체 및 그 제조방법
AU3809999A (en) 1998-05-18 1999-12-06 Novo Nordisk A/S Novel 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes
US6277991B1 (en) * 1998-05-18 2001-08-21 Novo Nordisk A/S 1,3,8-triazaspiro[4.5]decanones with high affinity for opioid receptor subtypes
SI0970957T1 (da) * 1998-06-12 2001-12-31 Hoffmann La Roche
EP0963985B1 (en) * 1998-06-12 2003-03-12 F. Hoffmann-La Roche Ag Di-or triaza-spiro(4,5)decane derivatives
ID29137A (id) 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
MA26659A1 (fr) * 1998-08-06 2004-12-20 Pfizer Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation.
JP2000053686A (ja) 1998-08-12 2000-02-22 Yushi Seihin Kk フルオロアルキルアルコキシシラン及びその製造方法
CO5150201A1 (es) 1998-09-07 2002-04-29 Hoffmann La Roche Derivados de piperidina
EP0997464B1 (en) 1998-10-23 2005-02-16 Pfizer Inc. 1,3,8-Triazaspiro[4,5] decanone compounds as orl1-receptor agonists
IT1303737B1 (it) 1998-11-11 2001-02-23 Smithkline Beecham Spa Derivati fenilpiperidinici procedimento per la loro preparazione eloro uso come ligandi del recettore orl-1.
AU1185300A (en) 1998-11-20 2000-06-13 Banyu Pharmaceutical Co., Ltd. 2-oxoimidazole derivatives
US6340681B1 (en) 1999-07-16 2002-01-22 Pfizer Inc 2-benzimidazolylamine compounds as ORL-1-receptor agonists
JP2001058991A (ja) 1999-08-20 2001-03-06 Banyu Pharmaceut Co Ltd スルホンアミド誘導体
EP1222185A1 (en) * 1999-10-18 2002-07-17 Smithkline Beecham Plc Tetrahydrobenzindolone derivatives, their preparation and their use as 5-ht7 receptor antagonists
EP1244437A4 (en) * 1999-12-06 2005-02-09 Euro Celtique Sa TERTIARY AMINO COMPOUNDS HAVING AFFINITY FOR OPIOID RECEPTOR
WO2001039775A1 (en) 1999-12-06 2001-06-07 Euro-Celtique, S.A. Benzimidazole compounds having nociceptin receptor affinity
DE60023100T2 (de) * 2000-01-05 2006-07-06 Pfizer Inc. Benzimidazol-Verbindungen zur Verwendung als ORL1-Rezeptor-Antagonisten
AU2001283955B2 (en) * 2000-07-31 2006-05-18 F. Hoffmann-La Roche Ag Piperazine derivatives
WO2002026714A1 (fr) 2000-09-27 2002-04-04 Takeda Chemical Industries, Ltd. Composes spiraniques
MXPA03009602A (es) 2001-04-18 2004-04-02 Euro Celtique Sa Analogos de nociceptina.
EP2033644A1 (en) * 2001-04-18 2009-03-11 Euro-Celtique S.A. Spiroindene and spiroindane compounds
PL367263A1 (en) 2001-04-18 2005-02-21 Euro-Celtique, S.A. Spiropyrazole compounds
ATE456564T1 (de) 2001-04-18 2010-02-15 Euro Celtique Sa Octahydrobenzimidazolon-verbindungen als analgetika
US20030078278A1 (en) * 2001-06-26 2003-04-24 Pfizer Inc. Spiropiperidine compounds as ligands for ORL-1 receptor
DE60226874D1 (de) * 2001-07-23 2008-07-10 Banyu Pharma Co Ltd 4-oxoimidazolidin-2-spiro piperidin derivat

Also Published As

Publication number Publication date
JP4056977B2 (ja) 2008-03-05
ES2392340T3 (es) 2012-12-07
EP1491212A1 (en) 2004-12-29
EP1491212B1 (en) 2012-08-08
PT1491212E (pt) 2012-11-16
EP1491212A4 (en) 2009-10-28
US20090253747A1 (en) 2009-10-08
US7566728B2 (en) 2009-07-28
JPWO2003082333A1 (ja) 2005-07-28
US20050119308A1 (en) 2005-06-02
AU2003220886A1 (en) 2003-10-13
US8003669B2 (en) 2011-08-23
WO2003082333A1 (fr) 2003-10-09

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