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DK1140993T3 - Glycopeptidderivater og farmaceutiske præparater indeholdende dem - Google Patents

Glycopeptidderivater og farmaceutiske præparater indeholdende dem

Info

Publication number
DK1140993T3
DK1140993T3 DK99965331T DK99965331T DK1140993T3 DK 1140993 T3 DK1140993 T3 DK 1140993T3 DK 99965331 T DK99965331 T DK 99965331T DK 99965331 T DK99965331 T DK 99965331T DK 1140993 T3 DK1140993 T3 DK 1140993T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical preparations
preparations containing
derivatives
glycopeptide
glycopeptide derivatives
Prior art date
Application number
DK99965331T
Other languages
Danish (da)
English (en)
Inventor
J Kevin Judice
Paul Ross Fatheree
Bernice M T Lam
Michael Leadbetter
Martin Sheringham Linsell
Yongqi Mu
Yan Zhu
Sean Gary Trapp
Guang Yang
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Application granted granted Critical
Publication of DK1140993T3 publication Critical patent/DK1140993T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK99965331T 1998-12-23 1999-12-22 Glycopeptidderivater og farmaceutiske præparater indeholdende dem DK1140993T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11372898P 1998-12-23 1998-12-23
US12931399P 1999-04-14 1999-04-14
US16402499P 1999-11-04 1999-11-04
US16997899P 1999-12-10 1999-12-10
PCT/US1999/030543 WO2000039156A1 (en) 1998-12-23 1999-12-22 Glycopeptide derivatives and pharmaceutical compositions containing the same

Publications (1)

Publication Number Publication Date
DK1140993T3 true DK1140993T3 (da) 2003-10-06

Family

ID=27493926

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99965331T DK1140993T3 (da) 1998-12-23 1999-12-22 Glycopeptidderivater og farmaceutiske præparater indeholdende dem

Country Status (23)

Country Link
US (9) US6392012B1 (zh)
EP (1) EP1140993B1 (zh)
JP (1) JP4362017B2 (zh)
KR (1) KR100665204B1 (zh)
CN (1) CN1249081C (zh)
AT (1) ATE242783T1 (zh)
AU (1) AU768204B2 (zh)
BR (1) BRPI9914221B8 (zh)
CA (1) CA2336445C (zh)
CZ (1) CZ301184B6 (zh)
DE (1) DE69908819T2 (zh)
DK (1) DK1140993T3 (zh)
ES (1) ES2201825T3 (zh)
HK (1) HK1040721B (zh)
HU (1) HU230190B1 (zh)
IL (2) IL140093A0 (zh)
NO (1) NO326066B1 (zh)
NZ (1) NZ508594A (zh)
PL (1) PL198311B1 (zh)
PT (1) PT1140993E (zh)
SI (1) SI1140993T1 (zh)
WO (1) WO2000039156A1 (zh)
ZA (1) ZA200007222B (zh)

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CN1249081C (zh) * 1998-12-23 2006-04-05 施万制药 糖肽衍生物或含有它们的药物组合物
US6699836B2 (en) * 1999-04-02 2004-03-02 The Trustees Of Princeton University Vancomycin analogs
US6518243B1 (en) * 1999-04-02 2003-02-11 Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
WO2001057071A2 (en) * 2000-02-04 2001-08-09 Advanced Medicine, Inc. Glycopeptide derivatives having antibiotic activity
ES2311014T3 (es) 2000-05-02 2009-02-01 Theravance, Inc. Procedimiento de alquilacion reductora en glicopeptidos.
WO2001083520A2 (en) * 2000-05-02 2001-11-08 Theravance,Inc Polyacid glycopeptide derivatives
EP1278549B1 (en) 2000-05-02 2008-12-10 Theravance, Inc. Composition containing a cyclodextrin and a glycopeptide antibiotic
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
US6620781B2 (en) * 2000-06-22 2003-09-16 Theravance, Inc. Glycopeptide carboxy-saccharide derivatives
US6828299B2 (en) 2000-06-22 2004-12-07 Theravance, Inc. Polyhydroxy glycopeptide derivatives
UA75083C2 (uk) 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
TWI275594B (en) * 2001-08-24 2007-03-11 Theravance Inc Process for preparing vancomycin phosphonate derivatives
TWI312785B (en) * 2001-08-24 2009-08-01 Theravance Inc Process for preparing vancomycin derivatives
DE60118737T2 (de) 2001-09-19 2006-10-19 The Procter & Gamble Company, Cincinnati Farbbedruckte Mehrschichtstruktur, ein damit hergestellter absorbierender Artikel und Verfahren zu deren Herstellung
TWI335332B (en) 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
US7652039B2 (en) 2002-05-17 2010-01-26 Sequella, Inc. Methods of use and compositions for the diagnosis and treatment of infectious disease
US20040033986A1 (en) * 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
AU2003231833A1 (en) * 2002-05-24 2003-12-12 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics
WO2003106399A2 (en) 2002-06-17 2003-12-24 Theravance, Inc. PROCESS FOR PREPARING N-PROTECTED β-AMINO ALDEHYDE COMPOUNDS
AU2003248896B2 (en) * 2002-07-09 2010-04-22 Fasgen, Llc Methods of treating microbial infections in humans and animals
CA2506236C (en) * 2002-11-18 2018-07-17 Vicuron Pharmaceuticals Inc. Compositions and uses of dalbavancin for treatment of bacterial infections
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
JP2007500222A (ja) * 2003-05-23 2007-01-11 セラヴァンス インコーポレーテッド 架橋グリコペプチド−セファロスポリン抗生物質
US7067482B2 (en) 2003-07-11 2006-06-27 Theravance, Inc. Cross-linked glycopeptide-cephalosporin antibiotics
DE102004055582A1 (de) 2004-11-18 2006-05-24 Bayer Cropscience Ag N-Heterocyclyl-phthalsäurediamide
JP4330169B2 (ja) 2004-11-29 2009-09-16 国立大学法人名古屋大学 グリコペプチド抗生物質モノマー誘導体
US8304597B2 (en) 2004-12-15 2012-11-06 The Procter And Gamble Company Method of using an absorbent article having a functional enhancement indicator
US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7632918B2 (en) * 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
EP1926780B1 (en) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
WO2007038246A2 (en) 2005-09-22 2007-04-05 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
WO2007084507A2 (en) * 2006-01-13 2007-07-26 The Scripps Research Institute [ψ[CH2NH]PG4] GLYCOPEPTIDE ANTIBIOTIC ANALOGS
TW200808818A (en) * 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
CA2710602A1 (en) * 2007-12-26 2009-07-09 Lead Therapeutics, Inc. Novel semi-synthetic glycopeptides as antibacterial agents
KR20100109934A (ko) 2007-12-26 2010-10-11 시오노기세야쿠 가부시키가이샤 글리코펩티드 항생 물질 배당화 유도체
EP2260060A4 (en) 2008-04-01 2013-01-16 Univ Cornell ORGANIC SOLUBLE CHITOSA SALT AND CHITOSAN DERIVED BIOMATERIALS MANUFACTURED THEREFROM
GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
CN101928330B (zh) * 2009-06-26 2013-10-16 上海来益生物药物研究开发中心有限责任公司 一种新的化合物及其应用
CA2868343A1 (en) * 2011-03-24 2012-09-27 Seachaid Pharmaceuticals, Inc. Vancomycin derivatives
JP6617097B2 (ja) 2013-03-15 2019-12-04 メリンタ サブシディアリー コーポレーション 抗生物質を用いて過体重および肥満の患者における感染を治療するための組成物
EP3049115A1 (en) * 2013-09-23 2016-08-03 Jawaharlal Nehru Centre For Advanced Scientific Research Vancomycin-sugar conjugates and uses thereof
EP3240574A1 (en) * 2014-12-25 2017-11-08 Jawaharlal Nehru Centre For Advanced Scientific Research Glycopeptides and uses thereof
US20190203240A1 (en) * 2016-01-15 2019-07-04 Universitaet Hamburg Methods for the production of rhamnosylated flavonoids
CN108698974A (zh) * 2016-01-28 2018-10-23 阿卡特肖勒公司 光裂解底漆组合物和使用方法
CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
KR102661790B1 (ko) 2017-05-22 2024-04-26 인스메드 인코포레이티드 리포-글리코펩티드 절단성 유도체 및 이의 용도
CN107987131B (zh) * 2017-11-16 2021-03-09 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的化合物、其制备方法和应用
CN108409837B (zh) 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用
NL2023883B1 (en) * 2019-09-24 2021-04-26 Univ Leiden Antibiotic compounds
CN111620931B (zh) * 2020-06-12 2021-12-17 苏州博源医疗科技有限公司 万古霉素衍生物及其制备方法和应用
CN114213284B (zh) * 2022-01-04 2023-08-01 丽珠集团福州福兴医药有限公司 (9h-芴-9-基)-癸基(2-氧代乙基)氨基甲酸甲酯及其合成方法

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UA75083C2 (uk) * 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
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Also Published As

Publication number Publication date
CZ200122A3 (en) 2001-06-13
PL348451A1 (en) 2002-05-20
US6962970B2 (en) 2005-11-08
DE69908819T2 (de) 2004-05-06
NO20006323D0 (no) 2000-12-12
CA2336445C (en) 2011-07-19
BR9914221A (pt) 2001-06-26
US7351791B2 (en) 2008-04-01
KR20010085857A (ko) 2001-09-07
JP4362017B2 (ja) 2009-11-11
PL198311B1 (pl) 2008-06-30
ATE242783T1 (de) 2003-06-15
US7723470B2 (en) 2010-05-25
US8030445B2 (en) 2011-10-04
HUP0400887A2 (hu) 2004-08-30
EP1140993B1 (en) 2003-06-11
AU3127300A (en) 2000-07-31
JP2002533472A (ja) 2002-10-08
US20090215982A1 (en) 2009-08-27
NZ508594A (en) 2003-05-30
US20050239690A1 (en) 2005-10-27
CZ301184B6 (cs) 2009-12-02
US20080103292A1 (en) 2008-05-01
AU768204B2 (en) 2003-12-04
BRPI9914221B8 (pt) 2021-05-25
IL140093A (en) 2006-06-11
IL140093A0 (en) 2002-02-10
WO2000039156A1 (en) 2000-07-06
HK1040721A1 (en) 2002-06-21
US6455669B1 (en) 2002-09-24
US20060241024A1 (en) 2006-10-26
NO326066B1 (no) 2008-09-08
US6392012B1 (en) 2002-05-21
CN1315961A (zh) 2001-10-03
EP1140993A1 (en) 2001-10-10
ES2201825T3 (es) 2004-03-16
NO20006323L (no) 2001-02-12
BR9914221B1 (pt) 2013-12-31
US6444786B1 (en) 2002-09-03
KR100665204B1 (ko) 2007-01-04
PT1140993E (pt) 2003-10-31
HK1040721B (zh) 2003-10-17
US7101964B2 (en) 2006-09-05
ZA200007222B (en) 2002-03-06
US20030060598A1 (en) 2003-03-27
US6949681B2 (en) 2005-09-27
CN1249081C (zh) 2006-04-05
SI1140993T1 (en) 2003-12-31
US20040204346A1 (en) 2004-10-14
HUP0400887A3 (en) 2012-09-28
DE69908819D1 (de) 2003-07-17
CA2336445A1 (en) 2000-07-06
HU230190B1 (hu) 2015-09-28

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