DK1140993T3 - Glycopeptidderivater og farmaceutiske præparater indeholdende dem - Google Patents
Glycopeptidderivater og farmaceutiske præparater indeholdende demInfo
- Publication number
- DK1140993T3 DK1140993T3 DK99965331T DK99965331T DK1140993T3 DK 1140993 T3 DK1140993 T3 DK 1140993T3 DK 99965331 T DK99965331 T DK 99965331T DK 99965331 T DK99965331 T DK 99965331T DK 1140993 T3 DK1140993 T3 DK 1140993T3
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutical preparations
- preparations containing
- derivatives
- glycopeptide
- glycopeptide derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11372898P | 1998-12-23 | 1998-12-23 | |
US12931399P | 1999-04-14 | 1999-04-14 | |
US16402499P | 1999-11-04 | 1999-11-04 | |
US16997899P | 1999-12-10 | 1999-12-10 | |
PCT/US1999/030543 WO2000039156A1 (en) | 1998-12-23 | 1999-12-22 | Glycopeptide derivatives and pharmaceutical compositions containing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1140993T3 true DK1140993T3 (da) | 2003-10-06 |
Family
ID=27493926
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99965331T DK1140993T3 (da) | 1998-12-23 | 1999-12-22 | Glycopeptidderivater og farmaceutiske præparater indeholdende dem |
Country Status (23)
Country | Link |
---|---|
US (9) | US6392012B1 (zh) |
EP (1) | EP1140993B1 (zh) |
JP (1) | JP4362017B2 (zh) |
KR (1) | KR100665204B1 (zh) |
CN (1) | CN1249081C (zh) |
AT (1) | ATE242783T1 (zh) |
AU (1) | AU768204B2 (zh) |
BR (1) | BRPI9914221B8 (zh) |
CA (1) | CA2336445C (zh) |
CZ (1) | CZ301184B6 (zh) |
DE (1) | DE69908819T2 (zh) |
DK (1) | DK1140993T3 (zh) |
ES (1) | ES2201825T3 (zh) |
HK (1) | HK1040721B (zh) |
HU (1) | HU230190B1 (zh) |
IL (2) | IL140093A0 (zh) |
NO (1) | NO326066B1 (zh) |
NZ (1) | NZ508594A (zh) |
PL (1) | PL198311B1 (zh) |
PT (1) | PT1140993E (zh) |
SI (1) | SI1140993T1 (zh) |
WO (1) | WO2000039156A1 (zh) |
ZA (1) | ZA200007222B (zh) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1249081C (zh) * | 1998-12-23 | 2006-04-05 | 施万制药 | 糖肽衍生物或含有它们的药物组合物 |
US6699836B2 (en) * | 1999-04-02 | 2004-03-02 | The Trustees Of Princeton University | Vancomycin analogs |
US6518243B1 (en) * | 1999-04-02 | 2003-02-11 | Trustees Of Princeton University | Desleucyl glycopeptide antibiotics and methods of making same |
WO2001057071A2 (en) * | 2000-02-04 | 2001-08-09 | Advanced Medicine, Inc. | Glycopeptide derivatives having antibiotic activity |
ES2311014T3 (es) | 2000-05-02 | 2009-02-01 | Theravance, Inc. | Procedimiento de alquilacion reductora en glicopeptidos. |
WO2001083520A2 (en) * | 2000-05-02 | 2001-11-08 | Theravance,Inc | Polyacid glycopeptide derivatives |
EP1278549B1 (en) | 2000-05-02 | 2008-12-10 | Theravance, Inc. | Composition containing a cyclodextrin and a glycopeptide antibiotic |
US6872804B2 (en) | 2000-06-22 | 2005-03-29 | Theravance, Inc. | Glycopeptide disulfide and thioester derivatives |
US6620781B2 (en) * | 2000-06-22 | 2003-09-16 | Theravance, Inc. | Glycopeptide carboxy-saccharide derivatives |
US6828299B2 (en) | 2000-06-22 | 2004-12-07 | Theravance, Inc. | Polyhydroxy glycopeptide derivatives |
UA75083C2 (uk) | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
US6905669B2 (en) * | 2001-04-24 | 2005-06-14 | Supergen, Inc. | Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase |
TWI275594B (en) * | 2001-08-24 | 2007-03-11 | Theravance Inc | Process for preparing vancomycin phosphonate derivatives |
TWI312785B (en) * | 2001-08-24 | 2009-08-01 | Theravance Inc | Process for preparing vancomycin derivatives |
DE60118737T2 (de) | 2001-09-19 | 2006-10-19 | The Procter & Gamble Company, Cincinnati | Farbbedruckte Mehrschichtstruktur, ein damit hergestellter absorbierender Artikel und Verfahren zu deren Herstellung |
TWI335332B (en) | 2001-10-12 | 2011-01-01 | Theravance Inc | Cross-linked vancomycin-cephalosporin antibiotics |
US7652039B2 (en) | 2002-05-17 | 2010-01-26 | Sequella, Inc. | Methods of use and compositions for the diagnosis and treatment of infectious disease |
US20040033986A1 (en) * | 2002-05-17 | 2004-02-19 | Protopopova Marina Nikolaevna | Anti tubercular drug: compositions and methods |
AU2003231833A1 (en) * | 2002-05-24 | 2003-12-12 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
WO2003106399A2 (en) | 2002-06-17 | 2003-12-24 | Theravance, Inc. | PROCESS FOR PREPARING N-PROTECTED β-AMINO ALDEHYDE COMPOUNDS |
AU2003248896B2 (en) * | 2002-07-09 | 2010-04-22 | Fasgen, Llc | Methods of treating microbial infections in humans and animals |
CA2506236C (en) * | 2002-11-18 | 2018-07-17 | Vicuron Pharmaceuticals Inc. | Compositions and uses of dalbavancin for treatment of bacterial infections |
US20060074014A1 (en) * | 2002-11-18 | 2006-04-06 | Vicuron Pharmaceuticals Inc. | Dalbavancin compositions for treatment of bacterial infections |
JP2007500222A (ja) * | 2003-05-23 | 2007-01-11 | セラヴァンス インコーポレーテッド | 架橋グリコペプチド−セファロスポリン抗生物質 |
US7067482B2 (en) | 2003-07-11 | 2006-06-27 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
DE102004055582A1 (de) | 2004-11-18 | 2006-05-24 | Bayer Cropscience Ag | N-Heterocyclyl-phthalsäurediamide |
JP4330169B2 (ja) | 2004-11-29 | 2009-09-16 | 国立大学法人名古屋大学 | グリコペプチド抗生物質モノマー誘導体 |
US8304597B2 (en) | 2004-12-15 | 2012-11-06 | The Procter And Gamble Company | Method of using an absorbent article having a functional enhancement indicator |
US7368422B2 (en) * | 2005-02-28 | 2008-05-06 | Novartis Vaccines And Diagnostics Inc. | Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity |
US7632918B2 (en) * | 2005-02-28 | 2009-12-15 | Novartis Vaccines And Diagnostics, Inc. | Semi-synthetic glycopeptides with antibiotic activity |
US20070185015A1 (en) * | 2005-02-28 | 2007-08-09 | Chiron Corporation and North China Pharmaceutical Corporation | Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity |
EP1926780B1 (en) | 2005-09-22 | 2013-08-14 | Medivas, LLC | Bis-( -amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use |
WO2007038246A2 (en) | 2005-09-22 | 2007-04-05 | Medivas, Llc | Solid polymer delivery compositions and methods for use thereof |
WO2007084507A2 (en) * | 2006-01-13 | 2007-07-26 | The Scripps Research Institute | [ψ[CH2NH]PG4] GLYCOPEPTIDE ANTIBIOTIC ANALOGS |
TW200808818A (en) * | 2006-05-26 | 2008-02-16 | Shionogi & Co | Glycopeptide antibiotic derivatives |
CA2710602A1 (en) * | 2007-12-26 | 2009-07-09 | Lead Therapeutics, Inc. | Novel semi-synthetic glycopeptides as antibacterial agents |
KR20100109934A (ko) | 2007-12-26 | 2010-10-11 | 시오노기세야쿠 가부시키가이샤 | 글리코펩티드 항생 물질 배당화 유도체 |
EP2260060A4 (en) | 2008-04-01 | 2013-01-16 | Univ Cornell | ORGANIC SOLUBLE CHITOSA SALT AND CHITOSAN DERIVED BIOMATERIALS MANUFACTURED THEREFROM |
GB2465863A (en) * | 2008-12-05 | 2010-06-09 | Lead Therapeutics Inc | Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections |
CN101928330B (zh) * | 2009-06-26 | 2013-10-16 | 上海来益生物药物研究开发中心有限责任公司 | 一种新的化合物及其应用 |
CA2868343A1 (en) * | 2011-03-24 | 2012-09-27 | Seachaid Pharmaceuticals, Inc. | Vancomycin derivatives |
JP6617097B2 (ja) | 2013-03-15 | 2019-12-04 | メリンタ サブシディアリー コーポレーション | 抗生物質を用いて過体重および肥満の患者における感染を治療するための組成物 |
EP3049115A1 (en) * | 2013-09-23 | 2016-08-03 | Jawaharlal Nehru Centre For Advanced Scientific Research | Vancomycin-sugar conjugates and uses thereof |
EP3240574A1 (en) * | 2014-12-25 | 2017-11-08 | Jawaharlal Nehru Centre For Advanced Scientific Research | Glycopeptides and uses thereof |
US20190203240A1 (en) * | 2016-01-15 | 2019-07-04 | Universitaet Hamburg | Methods for the production of rhamnosylated flavonoids |
CN108698974A (zh) * | 2016-01-28 | 2018-10-23 | 阿卡特肖勒公司 | 光裂解底漆组合物和使用方法 |
CN107325159A (zh) * | 2016-04-29 | 2017-11-07 | 中国科学院上海药物研究所 | 一类万古霉素衍生物、其制备方法、药物组合物和用途 |
KR102661790B1 (ko) | 2017-05-22 | 2024-04-26 | 인스메드 인코포레이티드 | 리포-글리코펩티드 절단성 유도체 및 이의 용도 |
CN107987131B (zh) * | 2017-11-16 | 2021-03-09 | 上海来益生物药物研究开发中心有限责任公司 | 一组具有抗耐药性细菌活性的化合物、其制备方法和应用 |
CN108409837B (zh) | 2018-03-06 | 2021-09-24 | 上海来益生物药物研究开发中心有限责任公司 | 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用 |
NL2023883B1 (en) * | 2019-09-24 | 2021-04-26 | Univ Leiden | Antibiotic compounds |
CN111620931B (zh) * | 2020-06-12 | 2021-12-17 | 苏州博源医疗科技有限公司 | 万古霉素衍生物及其制备方法和应用 |
CN114213284B (zh) * | 2022-01-04 | 2023-08-01 | 丽珠集团福州福兴医药有限公司 | (9h-芴-9-基)-癸基(2-氧代乙基)氨基甲酸甲酯及其合成方法 |
Family Cites Families (39)
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---|---|---|---|---|
US4497802A (en) | 1983-10-21 | 1985-02-05 | Eli Lilly And Company | N-Acyl glycopeptide derivatives |
US4914187A (en) | 1984-11-13 | 1990-04-03 | Gruppo Lepetit S.P.A | Ester derivatives of antibiotic L 17046 |
GB8428619D0 (en) * | 1984-11-13 | 1984-12-19 | Lepetit Spa | Derivatives of antibiotic l 17046 |
US4698327A (en) | 1985-04-25 | 1987-10-06 | Eli Lilly And Company | Novel glycopeptide derivatives |
US4639433A (en) | 1985-08-14 | 1987-01-27 | Eli Lilly And Company | Glycopeptide derivatives |
US4643987A (en) | 1985-08-14 | 1987-02-17 | Eli Lilly And Company | Modified glycopeptides |
GB8704847D0 (en) | 1987-03-02 | 1987-04-08 | Lepetit Spa | Substituted alkylamides of teicoplanin compounds |
FR2632185B1 (fr) * | 1988-06-01 | 1992-05-22 | Rhone Poulenc Chimie | Silice pour compositions dentifrices compatible notamment avec le zinc |
GB8817397D0 (en) * | 1988-07-21 | 1988-08-24 | Lepetit Spa | N15-alkyl & n15 n15-di-alkyl derivatives of teicoplanin antibiotics carrying functional groups on alkyl side chain |
US5534420A (en) | 1988-07-28 | 1996-07-09 | Eli Lilly And Company | Biotransformation of glycopeptide antibiotics |
ATE134646T1 (de) | 1988-12-27 | 1996-03-15 | Lepetit Spa | C63-amidderivate von 34-de(acetylglucosaminyl)-34-deoxy-teicoplanine |
IE64155B1 (en) | 1989-03-29 | 1995-07-12 | Lepetit Spa | New substituted alkylamide derivatives of teicoplanin |
CA2031803C (en) | 1989-12-13 | 2001-05-29 | Ramakrishnan Nagarajan | Improvements in or relating to glycopeptide deriveratives |
AU647122B2 (en) | 1990-05-28 | 1994-03-17 | Gruppo Lepetit S.P.A. | C63-amide derivatives of 34-de(acetylglucosaminyl)-34-deoxy- teicoplanin and their use as medicaments against bacteria resistant to glycopeptide antibiotics |
WO1992017456A1 (en) | 1991-03-26 | 1992-10-15 | Fujisawa Pharmaceutical Co., Ltd. | Amino acid derivative and salt thereof |
WO1993003060A1 (en) | 1991-07-29 | 1993-02-18 | Gruppo Lepetit S.P.A. | Amide derivatives of antibiotic a 40926 |
US5750509A (en) | 1991-07-29 | 1998-05-12 | Gruppo Lepetit S.P.A. | Amide derivatives of antibiotic A 40926 |
US5840684A (en) * | 1994-01-28 | 1998-11-24 | Eli Lilly And Company | Glycopeptide antibiotic derivatives |
RU2145609C1 (ru) * | 1994-01-28 | 2000-02-20 | Эли Лилли Энд Компани | Производные гликопептида или их соли, способ получения, фармацевтическая композиция |
IT1282586B1 (it) | 1996-02-08 | 1998-03-31 | Chemical And Biolog Ind | Composizioni farmaceutiche per il trattamento biologico delle infezioni dovute a ceppi di enterococcus faecium resistenti agli |
CA2249323A1 (en) | 1996-03-21 | 1997-09-25 | Transcell Technologies, Inc. | Solid phase lipoglycopeptide library, compositions and methods |
AU2441697A (en) | 1996-04-12 | 1997-11-07 | Eli Lilly And Company | Covalently-linked glycopeptide dimers |
WO1997038706A1 (en) | 1996-04-12 | 1997-10-23 | Eli Lilly And Company | Glycopeptide compounds |
EP0912604B1 (en) | 1996-04-23 | 2001-11-14 | Biosearch Italia S.p.A. | Improved chemical process for preparing amide derivatives of antibiotic A 40926 |
US5919756A (en) | 1996-06-28 | 1999-07-06 | Eli Lilly And Company | Amides |
US5952466A (en) | 1997-11-12 | 1999-09-14 | Eli Lilly And Company | Reductive alkylation of glycopeptide antibiotics |
US5939382A (en) | 1996-11-21 | 1999-08-17 | Eli Lilly And Company | Reducing agent for reductive alkylation of glycopeptide antibiotics |
US5916873A (en) | 1997-04-17 | 1999-06-29 | Eli Lilly And Company | Teicoplanin derivatives |
US5977063A (en) | 1997-05-20 | 1999-11-02 | Eli Lilly And Company | Alkylated hexapeptides |
US5919771A (en) | 1997-05-20 | 1999-07-06 | Eli Lilly And Company | Urea and thiourea derivatives of glycopeptides |
US5952310A (en) | 1997-05-20 | 1999-09-14 | Eli Lilly And Company | Glycopeptide hexapeptides |
US6518242B1 (en) * | 1998-02-20 | 2003-02-11 | Theravance, Inc. | Derivatives of glycopeptide antibacterial agents |
WO1999042476A1 (en) | 1998-02-20 | 1999-08-26 | Advanced Medicine, Inc. | Novel antibacterial agents |
ES2283107T3 (es) | 1998-05-01 | 2007-10-16 | Eli Lilly And Company | Glicopeptidos modificados en n1. |
WO2000004044A1 (en) | 1998-07-14 | 2000-01-27 | Princeton University | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same |
CN1249081C (zh) | 1998-12-23 | 2006-04-05 | 施万制药 | 糖肽衍生物或含有它们的药物组合物 |
UA75083C2 (uk) * | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
AU2003231833A1 (en) * | 2002-05-24 | 2003-12-12 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
US7067482B2 (en) * | 2003-07-11 | 2006-06-27 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
-
1999
- 1999-12-22 CN CNB99809434XA patent/CN1249081C/zh not_active Expired - Lifetime
- 1999-12-22 BR BRPI9914221A patent/BRPI9914221B8/pt not_active IP Right Cessation
- 1999-12-22 ES ES99965331T patent/ES2201825T3/es not_active Expired - Lifetime
- 1999-12-22 AT AT99965331T patent/ATE242783T1/de active
- 1999-12-22 JP JP2000591067A patent/JP4362017B2/ja not_active Expired - Fee Related
- 1999-12-22 US US09/470,209 patent/US6392012B1/en not_active Expired - Lifetime
- 1999-12-22 WO PCT/US1999/030543 patent/WO2000039156A1/en active IP Right Grant
- 1999-12-22 AU AU31273/00A patent/AU768204B2/en not_active Expired
- 1999-12-22 CZ CZ20010022A patent/CZ301184B6/cs not_active IP Right Cessation
- 1999-12-22 EP EP99965331A patent/EP1140993B1/en not_active Expired - Lifetime
- 1999-12-22 PL PL348451A patent/PL198311B1/pl unknown
- 1999-12-22 IL IL14009399A patent/IL140093A0/xx active IP Right Grant
- 1999-12-22 HU HU0400887A patent/HU230190B1/hu unknown
- 1999-12-22 KR KR1020017003918A patent/KR100665204B1/ko active IP Right Grant
- 1999-12-22 DE DE69908819T patent/DE69908819T2/de not_active Expired - Lifetime
- 1999-12-22 DK DK99965331T patent/DK1140993T3/da active
- 1999-12-22 SI SI9930389T patent/SI1140993T1/xx unknown
- 1999-12-22 PT PT99965331T patent/PT1140993E/pt unknown
- 1999-12-22 CA CA2336445A patent/CA2336445C/en not_active Expired - Lifetime
- 1999-12-22 NZ NZ508594A patent/NZ508594A/en not_active IP Right Cessation
-
2000
- 2000-09-06 US US09/656,473 patent/US6444786B1/en not_active Expired - Lifetime
- 2000-11-01 US US09/674,456 patent/US6455669B1/en not_active Expired - Lifetime
- 2000-12-05 IL IL140093A patent/IL140093A/en not_active IP Right Cessation
- 2000-12-06 ZA ZA200007222A patent/ZA200007222B/xx unknown
- 2000-12-12 NO NO20006323A patent/NO326066B1/no not_active IP Right Cessation
-
2002
- 2002-03-06 US US10/092,088 patent/US6962970B2/en not_active Expired - Lifetime
- 2002-03-21 HK HK02102171.5A patent/HK1040721B/zh unknown
-
2004
- 2004-04-15 US US10/825,038 patent/US6949681B2/en not_active Expired - Lifetime
-
2005
- 2005-05-13 US US11/128,901 patent/US7101964B2/en not_active Expired - Lifetime
-
2006
- 2006-04-17 US US11/405,234 patent/US7351791B2/en not_active Expired - Fee Related
-
2007
- 2007-10-24 US US11/977,377 patent/US7723470B2/en not_active Expired - Fee Related
-
2009
- 2009-05-08 US US12/437,778 patent/US8030445B2/en not_active Expired - Fee Related
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