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DK1062358T3 - Ny fremgangsmåde til fremstilling af fexofenadin - Google Patents

Ny fremgangsmåde til fremstilling af fexofenadin

Info

Publication number
DK1062358T3
DK1062358T3 DK99909036T DK99909036T DK1062358T3 DK 1062358 T3 DK1062358 T3 DK 1062358T3 DK 99909036 T DK99909036 T DK 99909036T DK 99909036 T DK99909036 T DK 99909036T DK 1062358 T3 DK1062358 T3 DK 1062358T3
Authority
DK
Denmark
Prior art keywords
fexofenadine
preparation
new method
new
Prior art date
Application number
DK99909036T
Other languages
English (en)
Inventor
Robert Azerad
Jacques Biton
Isabelle Lacroix
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK1062358T3 publication Critical patent/DK1062358T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/59Hydrogenated pyridine rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • C12P17/12Nitrogen as only ring hetero atom containing a six-membered hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK99909036T 1998-03-19 1999-03-18 Ny fremgangsmåde til fremstilling af fexofenadin DK1062358T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9803349A FR2776302B1 (fr) 1998-03-19 1998-03-19 Nouveau procede de preparation de la fexofenadine
PCT/FR1999/000625 WO1999047693A1 (fr) 1998-03-19 1999-03-18 Nouveau procede de preparation de la fexofenadine

Publications (1)

Publication Number Publication Date
DK1062358T3 true DK1062358T3 (da) 2003-09-29

Family

ID=9524214

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99909036T DK1062358T3 (da) 1998-03-19 1999-03-18 Ny fremgangsmåde til fremstilling af fexofenadin

Country Status (15)

Country Link
US (2) US6558931B1 (da)
EP (1) EP1062358B1 (da)
JP (1) JP4291511B2 (da)
AR (1) AR014738A1 (da)
AT (1) ATE242333T1 (da)
AU (1) AU2842799A (da)
DE (1) DE69908569T2 (da)
DK (1) DK1062358T3 (da)
DZ (1) DZ2746A1 (da)
ES (1) ES2196783T3 (da)
FR (1) FR2776302B1 (da)
MA (1) MA26615A1 (da)
PT (1) PT1062358E (da)
TN (1) TNSN99042A1 (da)
WO (1) WO1999047693A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2776302B1 (fr) * 1998-03-19 2002-04-12 Hoechst Marion Roussel Inc Nouveau procede de preparation de la fexofenadine
GB0013368D0 (en) * 2000-05-31 2000-07-26 Pfizer Ltd Enzymatic oxidations
US6610518B2 (en) 2000-05-31 2003-08-26 Pfizer Inc. Enzymatic oxidations
US6613906B1 (en) 2000-06-06 2003-09-02 Geneva Pharmaceuticals, Inc. Crystal modification
GB0018691D0 (en) 2000-07-28 2000-09-20 Rolabo Sl Process
US6613907B2 (en) 2000-11-08 2003-09-02 Amr Technology, Inc. Process for the production of piperidine derivatives with microorganisms
AU2003209673B2 (en) * 2002-03-08 2007-10-18 M/S. Ind-Swift Limited Tasteless directly compressible fast-dissolving complexes and pharmaceutical formulations thereof
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6147216A (en) 1993-06-25 2000-11-14 Merrell Pharmaceuticals Inc. Intermediates useful for the preparation of antihistaminic piperidine derivatives
ES2190442T3 (es) 1993-06-25 2003-08-01 Merrell Pharma Inc Nuevos productos intermedios para la preparacion de derivados de 4-difenilmetil/difenilmetoxi piperidina antihistaminicos.
PT864653E (pt) * 1997-03-11 2004-08-31 Aventis Pharma Inc Processo para preparacao de acido 4-(4-(4-(hidroxidifenil)-1-piperidinil)-1-hidroxibutil)-alfa,alfa-dimetilfenilacetico e derivados fosforilados
FR2776302B1 (fr) * 1998-03-19 2002-04-12 Hoechst Marion Roussel Inc Nouveau procede de preparation de la fexofenadine

Also Published As

Publication number Publication date
WO1999047693A1 (fr) 1999-09-23
MA26615A1 (fr) 2004-12-20
JP4291511B2 (ja) 2009-07-08
FR2776302A1 (fr) 1999-09-24
PT1062358E (pt) 2003-10-31
DZ2746A1 (fr) 2003-09-08
US20060019358A1 (en) 2006-01-26
AU2842799A (en) 1999-10-11
ATE242333T1 (de) 2003-06-15
US7241601B2 (en) 2007-07-10
JP2002506653A (ja) 2002-03-05
US6558931B1 (en) 2003-05-06
EP1062358A1 (fr) 2000-12-27
DE69908569D1 (de) 2003-07-10
FR2776302B1 (fr) 2002-04-12
TNSN99042A1 (fr) 2005-11-10
DE69908569T2 (de) 2004-05-13
ES2196783T3 (es) 2003-12-16
EP1062358B1 (fr) 2003-06-04
AR014738A1 (es) 2001-03-28

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