DK0694039T3 - Derivater af 1,5-benzodiazepin med CCK-antagonistisk og agonistisk virkning - Google Patents

Derivater af 1,5-benzodiazepin med CCK-antagonistisk og agonistisk virkning

Info

Publication number: DK0694039T3
Authority: DK; Denmark
Prior art keywords: benzodiazepine; derivatives; agonistic effect; cck; antagonistic
Prior art date: 1993-04-15

Application number

DK94913580T

Other languages

Danish (da)

English (en)

Inventor

Elizabeth Ellen Sugg

Christopher Joseph Aquino

Jerzy Ryszard Szewczyk

Harry Finch

Robin Arthur Ellis Carr

Original Assignee

Glaxo Wellcome Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-04-15

Filing date

1994-04-14

Publication date

2001-05-21

1994-04-14 Application filed by Glaxo Wellcome Inc filed Critical Glaxo Wellcome Inc

2001-05-21 Application granted granted Critical

2001-05-21 Publication of DK0694039T3 publication Critical patent/DK0694039T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Crystallography & Structural Chemistry (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Hydrogenated Pyridines (AREA)

DK94913580T 1993-04-15 1994-04-14 Derivater af 1,5-benzodiazepin med CCK-antagonistisk og agonistisk virkning DK0694039T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939307833A GB9307833D0 (en)	1993-04-15	1993-04-15	Modulators of cholecystokinin and gastrin
PCT/EP1994/001131 WO1994024149A1 (en)	1993-04-15	1994-04-14	1,5-benzodiazepine derivatives having cck antagonistic or agonistic activity

Publications (1)

Publication Number	Publication Date
DK0694039T3 true DK0694039T3 (da)	2001-05-21

Family

ID=10733915

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94913580T DK0694039T3 (da)	1993-04-15	1994-04-14	Derivater af 1,5-benzodiazepin med CCK-antagonistisk og agonistisk virkning

Country Status (34)

Country	Link
US (2)	US5646140A (is)
EP (1)	EP0694039B1 (is)
JP (1)	JP3406317B2 (is)
KR (1)	KR100364948B1 (is)
CN (1)	CN1058487C (is)
AP (2)	AP462A (is)
AT (1)	ATE198894T1 (is)
AU (1)	AU681139B2 (is)
CA (1)	CA2158973C (is)
CZ (1)	CZ286695B6 (is)
DE (1)	DE69426624T2 (is)
DK (1)	DK0694039T3 (is)
EC (1)	ECSP941066A (is)
ES (1)	ES2154674T3 (is)
FI (1)	FI954853A (is)
GB (1)	GB9307833D0 (is)
GR (1)	GR3035641T3 (is)
HK (1)	HK1003943A1 (is)
HU (1)	HU223467B1 (is)
IL (2)	IL109315A0 (is)
IS (2)	IS4148A (is)
MY (2)	MY131569A (is)
NO (1)	NO311133B1 (is)
NZ (1)	NZ265272A (is)
OA (1)	OA10355A (is)
PE (2)	PE50994A1 (is)
PH (1)	PH30897A (is)
PL (1)	PL178790B1 (is)
PT (1)	PT694039E (is)
RU (1)	RU2135486C1 (is)
SK (1)	SK281211B6 (is)
TW (1)	TW487703B (is)
WO (1)	WO1994024149A1 (is)
ZA (2)	ZA942570B (is)

Families Citing this family (48)

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PT728748E (pt) *	1993-12-28	2002-06-28	Shionogi & Co	Novos derivados da benzodiazepina
BR9507381A (pt) *	1994-04-14	1997-09-23	Glaxo Wellcome Inc	Composto uso de um composto processo para o tratamento de um manifero composição famacèutica e processo para a preparação de compostos
US5739129A (en) *	1994-04-14	1998-04-14	Glaxo Wellcome Inc.	CCK or gastrin modulating 5-heterocyclic-1, 5 benzodiazepines
US5795887A (en) *	1994-04-15	1998-08-18	Glaxo Wellcome Inc.	Method of inducing cholecystokinin agonist activity using 1,4- Benzodiazepine compounds
PE27497A1 (es) *	1994-04-15	1997-08-07	Glaxo Inc	Derivados de 1,5 benzodiazepina
GB9420748D0 (en) *	1994-10-14	1994-11-30	Glaxo Inc	1,5 benzodiazepine derivatives
GB9420763D0 (en) *	1994-10-14	1994-11-30	Glaxo Inc	Acetamide derivatives
US5910495A (en) *	1994-10-14	1999-06-08	Glaxo Wellcome Inc.	Use of 1,5-benzo b!1,4-diazepines to control gastric emptying
GB9420747D0 (en) *	1994-10-14	1994-11-30	Glaxo Inc	1,5 benzodiazepine derivatives
US5780464A (en) *	1994-10-14	1998-07-14	Glaxo Wellcome Inc.	Enteric coated compositions of 1,5-benzodiazepine derivatives having CCK antagonistic or agonistic activity
US5750353A (en) *	1995-12-11	1998-05-12	New England Medical Center Hospitals, Inc.	Assay for non-peptide agonists to peptide hormone receptors
DE69637211T2 (de)	1995-12-11	2008-05-08	New England Medical Center Hospitals, Inc., Boston	Test für und verwendungen von liganden von peptidhormonrezeptoren.
US6239131B1 (en) *	1996-12-10	2001-05-29	Zeria Pharmaceutical Co., Ltd.	1,5 Benzodiazepine derivatives
EE9900497A (et)	1997-04-15	2000-06-15	Csir	Söögiisu pärssiva toimega farmatseutilised kompositsioonid
AR022044A1 (es) *	1999-05-06	2002-09-04	Glaxo Group Ltd	Derivados de 1,5-benzodiazepina
GB2396815B (en)	1999-10-27	2004-09-08	Phytopharm Plc	A composition comprising a pregnenone derivative and an NSAID
GB2363985B (en)	2000-06-30	2004-09-29	Phytopharm Plc	Extracts,compounds & pharmaceutical compositions having anti-diabetic activity and their use
US6768024B1 (en)	2000-08-04	2004-07-27	Lion Bioscience Ag	Triamine derivative melanocortin receptor ligands and methods of using same
US20020180095A1 (en) *	2001-05-29	2002-12-05	Berard Steven O.	Thermally conductive carbon fiber extrusion compounder and method of using same
US7074805B2 (en) *	2002-02-20	2006-07-11	Abbott Laboratories	Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
DE60325834D1 (de) *	2002-02-20	2009-03-05	Abbott Lab	Kondensierte azabicyclischeverbindungen als inhibitoren des vanilloid-rezeptors 1 (vr1)
US6933311B2 (en) *	2003-02-11	2005-08-23	Abbott Laboratories	Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
US7015233B2 (en) *	2003-06-12	2006-03-21	Abbott Laboratories	Fused compounds that inhibit vanilloid subtype 1 (VR1) receptor
CN1950374A (zh) *	2004-05-25	2007-04-18	辉瑞产品公司	四氮杂苯并[e]甘菊环衍生物及其类似物
CN1333077C (zh) *	2005-04-15	2007-08-22	华南农业大学	缩胆囊素活性片段的串联表达及其应用
JP2010501592A (ja) *	2006-08-25	2010-01-21	アボット・ラボラトリーズ	Ｔｒｐｖ１を阻害するインダゾール誘導体およびその使用
CA2672196A1 (en) *	2006-12-20	2008-07-03	Abbott Laboratories	Antagonists of the trpv1 receptor and uses thereof
CN102036969A (zh) *	2008-03-20	2011-04-27	雅培制药有限公司	制造作为trpv1拮抗剂的中枢神经系统药剂的方法
CN103102285B (zh) *	2013-01-30	2015-07-29	淮阴师范学院	对氨基苯乙腈的制备方法
WO2015074081A1 (en)	2013-11-18	2015-05-21	Bair Kenneth W	Benzopiperazine compositions as bet bromodomain inhibitors
NZ720004A (en)	2013-11-18	2020-03-27	Forma Therapeutics Inc	Tetrahydroquinoline compositions as bet bromodomain inhibitors
WO2017015449A1 (en)	2015-07-22	2017-01-26	Enanta Pharmaceuticals, Inc.	Benzodiazepine derivatives as rsv inhibitors
US9815850B2 (en)	2016-02-05	2017-11-14	Denali Therapeutics Inc.	Compounds, compositions and methods
EP3552017B1 (en)	2016-12-09	2022-02-23	Denali Therapeutics Inc.	Compounds useful as ripk1 inhibitors
US10358441B2 (en)	2017-02-16	2019-07-23	Enanta Pharmaceuticals, Inc.	Processes for the preparation of benzodiazepine derivatives
WO2018226801A1 (en) *	2017-06-07	2018-12-13	Enanta Pharmaceuticals, Inc.	Aryldiazepine derivatives as rsv inhibitors
WO2019006295A1 (en)	2017-06-30	2019-01-03	Enanta Pharmaceuticals, Inc.	HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
WO2019006291A1 (en)	2017-06-30	2019-01-03	Enanta Pharmaceuticals, Inc.	HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
KR102645995B1 (ko)	2017-09-29	2024-03-11	이난타 파마슈티칼스, 인코포레이티드	Rsv 억제제로서의 병용 약학 제제
US10647711B2 (en)	2017-11-13	2020-05-12	Enanta Pharmaceuticals, Inc.	Azepin-2-one derivatives as RSV inhibitors
US10975094B2 (en)	2018-04-11	2021-04-13	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as RSV inhibitors
EP3941525A4 (en)	2019-03-18	2022-12-07	Enanta Pharmaceuticals, Inc.	BENZODIAZEPIN DERIVATIVES AS RSV INHIBITORS
US11179400B2 (en)	2019-04-09	2021-11-23	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as RSV inhibitors
US11505558B1 (en)	2019-10-04	2022-11-22	Enanta Pharmaceuticals, Inc.	Antiviral heterocyclic compounds
UY39032A (es)	2020-01-24	2021-07-30	Enanta Pharm Inc	Compuestos heterocíclicos como agentes antivirales
US11534439B2 (en)	2020-07-07	2022-12-27	Enanta Pharmaceuticals, Inc.	Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors
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US11999750B2 (en)	2022-01-12	2024-06-04	Denali Therapeutics Inc.	Crystalline forms of (S)-5-benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydropyrido [3,2-B][1,4]oxazepin-3-yl)-4H-1,2,4-triazole-3-carboxamide

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FR2641280B1 (fr) *	1988-12-29	1994-01-21	Roussel Uclaf	Nouveaux derives de la 2,4-dioxo 2,3,4,5-tetrahydro 1h-1,5-benzodiazepine, leur procede de preparation et leur application comme medicaments
FR2659653B1 (fr) *	1990-03-13	1992-05-22	Rhone Poulenc Sante	Derives de l'uree, leur preparation et les medicaments les contenant.
US5206234A (en) *	1990-10-22	1993-04-27	Merck & Co., Inc.	Benzolactam analogs as antagonists of cck
JP2904941B2 (ja) *	1991-01-28	1999-06-14	出光興産株式会社	スチレン系重合体の精製方法
GEP20001968B (en) *	1992-01-21	2000-03-05	Glaxo Spa	Arilthio Compounds as Antibacterial and Antiviral Agents
BR9507381A (pt) *	1994-04-14	1997-09-23	Glaxo Wellcome Inc	Composto uso de um composto processo para o tratamento de um manifero composição famacèutica e processo para a preparação de compostos

1993
- 1993-04-15 GB GB939307833A patent/GB9307833D0/en active Pending
1994
- 1994-01-04 US US08/525,659 patent/US5646140A/en not_active Expired - Lifetime
- 1994-04-11 IS IS4148A patent/IS4148A/is unknown
- 1994-04-11 IS IS4147A patent/IS4147A/is unknown
- 1994-04-12 EC EC1994001066A patent/ECSP941066A/es unknown
- 1994-04-12 MY MYPI94000884A patent/MY131569A/en unknown
- 1994-04-12 MY MYPI94000880A patent/MY112237A/en unknown
- 1994-04-13 US US08/522,363 patent/US5585376A/en not_active Expired - Fee Related
- 1994-04-13 PE PE1994240027A patent/PE50994A1/es not_active Application Discontinuation
- 1994-04-13 AP APAP/P/1994/000634A patent/AP462A/en active
- 1994-04-13 IL IL10931594A patent/IL109315A0/xx unknown
- 1994-04-13 IL IL10931694A patent/IL109316A/en not_active IP Right Cessation
- 1994-04-13 PE PE1994240028A patent/PE50594A1/es not_active Application Discontinuation
- 1994-04-13 AP APAP/P/1994/000635A patent/AP512A/en active
- 1994-04-14 ES ES94913580T patent/ES2154674T3/es not_active Expired - Lifetime
- 1994-04-14 SK SK1253-95A patent/SK281211B6/sk unknown
- 1994-04-14 CZ CZ19952675A patent/CZ286695B6/cs not_active IP Right Cessation
- 1994-04-14 DE DE69426624T patent/DE69426624T2/de not_active Expired - Lifetime
- 1994-04-14 JP JP52273494A patent/JP3406317B2/ja not_active Expired - Fee Related
- 1994-04-14 NZ NZ265272A patent/NZ265272A/en not_active IP Right Cessation
- 1994-04-14 RU RU95117974A patent/RU2135486C1/ru not_active IP Right Cessation
- 1994-04-14 ZA ZA942570A patent/ZA942570B/xx unknown
- 1994-04-14 HU HU9502978A patent/HU223467B1/hu not_active IP Right Cessation
- 1994-04-14 DK DK94913580T patent/DK0694039T3/da active
- 1994-04-14 CN CN94191773A patent/CN1058487C/zh not_active Expired - Fee Related
- 1994-04-14 WO PCT/EP1994/001131 patent/WO1994024149A1/en active IP Right Grant
- 1994-04-14 AU AU65676/94A patent/AU681139B2/en not_active Ceased
- 1994-04-14 EP EP94913580A patent/EP0694039B1/en not_active Expired - Lifetime
- 1994-04-14 CA CA002158973A patent/CA2158973C/en not_active Expired - Fee Related
- 1994-04-14 AT AT94913580T patent/ATE198894T1/de not_active IP Right Cessation
- 1994-04-14 ZA ZA942571A patent/ZA942571B/xx unknown
- 1994-04-14 PL PL94311084A patent/PL178790B1/pl unknown
- 1994-04-14 PT PT94913580T patent/PT694039E/pt unknown
- 1994-04-14 KR KR1019950704491A patent/KR100364948B1/ko not_active IP Right Cessation
- 1994-04-14 PH PH48093A patent/PH30897A/en unknown
- 1994-05-26 TW TW083104772A patent/TW487703B/zh not_active IP Right Cessation
1995
- 1995-10-12 OA OA60722A patent/OA10355A/en unknown
- 1995-10-12 FI FI954853A patent/FI954853A/fi unknown
- 1995-10-13 NO NO19954090A patent/NO311133B1/no unknown
1998
- 1998-04-16 HK HK98103188A patent/HK1003943A1/xx not_active IP Right Cessation
2001
- 2001-03-27 GR GR20010400488T patent/GR3035641T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ265272A (en)	1997-07-27
US5646140A (en)	1997-07-08
IL109315A0 (en)	1994-07-31
HU9502978D0 (en)	1995-12-28
SK125395A3 (en)	1996-06-05
PT694039E (pt)	2001-06-29
IL109316A0 (en)	1994-07-31
PE50594A1 (es)	1995-01-06
AU681139B2 (en)	1997-08-21
EP0694039B1 (en)	2001-01-24
KR100364948B1 (ko)	2003-03-29
MY112237A (en)	2001-05-31
CZ267595A3 (en)	1996-04-17
HK1003943A1 (en)	1998-11-13
WO1994024149A1 (en)	1994-10-27
PL311084A1 (en)	1996-02-05
FI954853A0 (fi)	1995-10-12
ZA942571B (en)	1994-11-11
AP462A (en)	1996-02-19
ATE198894T1 (de)	2001-02-15
PL178790B1 (pl)	2000-06-30
AP9400634A0 (en)	1994-04-30
SK281211B6 (sk)	2001-01-18
PH30897A (en)	1997-12-23
NO954090L (no)	1995-12-13
GR3035641T3 (en)	2001-06-29
ES2154674T3 (es)	2001-04-16
RU2135486C1 (ru)	1999-08-27
DE69426624D1 (de)	2001-03-01
HU223467B1 (hu)	2004-07-28
CA2158973A1 (en)	1994-10-27
AP9400635A0 (en)	1994-04-30
US5585376A (en)	1996-12-17
IL109316A (en)	1999-03-12
IS4147A (is)	1994-10-16
CN1120843A (zh)	1996-04-17
OA10355A (en)	2001-10-19
FI954853A (fi)	1995-10-12
IS4148A (is)	1994-10-16
CA2158973C (en)	2006-06-06
AU6567694A (en)	1994-11-08
ZA942570B (en)	1994-11-11
CZ286695B6 (en)	2000-06-14
NO311133B1 (no)	2001-10-15
DE69426624T2 (de)	2001-06-21
PE50994A1 (es)	1995-01-06
TW487703B (en)	2002-05-21
CN1058487C (zh)	2000-11-15
MY131569A (en)	2007-08-30
HUT74102A (en)	1996-11-28
JP3406317B2 (ja)	2003-05-12
NO954090D0 (no)	1995-10-13
JPH08508744A (ja)	1996-09-17
AP512A (en)	1996-07-29
ECSP941066A (es)	1994-11-16
EP0694039A1 (en)	1996-01-31
GB9307833D0 (en)	1993-06-02

Publication	Publication Date	Title
DK0694039T3 (da)	2001-05-21	Derivater af 1,5-benzodiazepin med CCK-antagonistisk og agonistisk virkning
DE69417753D1 (de)	1999-05-12	Wegwerfbare monatsunterhose
DK0876392T3 (da)	2000-11-06	Lacton-derivater af 17.beta.-carboxy, carbothio og amidandrostanforbindelser
DE69223465D1 (de)	1998-01-22	Polymere Zusammensetzungen und Verwendung derselben
DE69708028D1 (de)	2001-12-13	1,2-Bis-Addukte von Introxyden mit substituierten Äthylenen und stabilisierte Zusammensetzungen
ITTO910114A1 (it)	1992-08-19	Composizioni e procedimento di placcatura
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