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DK0424232T3 - Fremgangsmåde til fremstilling af chenodesoxycholsyre - Google Patents

Fremgangsmåde til fremstilling af chenodesoxycholsyre

Info

Publication number
DK0424232T3
DK0424232T3 DK90402879.2T DK90402879T DK0424232T3 DK 0424232 T3 DK0424232 T3 DK 0424232T3 DK 90402879 T DK90402879 T DK 90402879T DK 0424232 T3 DK0424232 T3 DK 0424232T3
Authority
DK
Denmark
Prior art keywords
preparation
alpha
acid
alkali metal
oxocholanates
Prior art date
Application number
DK90402879.2T
Other languages
English (en)
Inventor
Emilio Crisafulli
Roberto Arosio
Vittorio Rossetti
Stefano Beratto
Armando Talamona
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8913571A external-priority patent/FR2653128B1/fr
Priority claimed from FR8913572A external-priority patent/FR2653129B1/fr
Priority claimed from FR8913570A external-priority patent/FR2653127B1/fr
Priority claimed from FR8913569A external-priority patent/FR2653126B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of DK0424232T3 publication Critical patent/DK0424232T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK90402879.2T 1989-10-17 1990-10-16 Fremgangsmåde til fremstilling af chenodesoxycholsyre DK0424232T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8913571A FR2653128B1 (fr) 1989-10-17 1989-10-17 Procede pour la preparation de l'acide chenodesoxycholique.
FR8913572A FR2653129B1 (fr) 1989-10-17 1989-10-17 Procede pour la preparation de 7-oxocholanates.
FR8913570A FR2653127B1 (fr) 1989-10-17 1989-10-17 Procede pour la preparation de 12-oxocholanates.
FR8913569A FR2653126B1 (fr) 1989-10-17 1989-10-17 Procede pour la preparation de diacetoxycholanates.

Publications (1)

Publication Number Publication Date
DK0424232T3 true DK0424232T3 (da) 1996-06-17

Family

ID=27446720

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90402879.2T DK0424232T3 (da) 1989-10-17 1990-10-16 Fremgangsmåde til fremstilling af chenodesoxycholsyre

Country Status (7)

Country Link
EP (1) EP0424232B1 (da)
AT (1) ATE134378T1 (da)
DE (1) DE69025449T2 (da)
DK (1) DK0424232T3 (da)
ES (1) ES2086388T3 (da)
GR (1) GR3019857T3 (da)
IE (1) IE73449B1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2105500A1 (de) 2008-03-26 2009-09-30 Pharmazell GmbH Neue 12alpha-Hydroxysteroiddehydrogenasen, deren Herstellung und deren Verwendung
CN101215311B (zh) * 2008-01-10 2010-10-27 辽宁百隆生物工程有限公司 用含量86%的鹅去氧胆酸生产熊去氧胆酸的生产方法
EP2333101A1 (de) 2009-12-11 2011-06-15 PharmaZell GmbH NAD(P)+-Cofaktorregenerierungssystem und dessen Anwendungen
CN102060902A (zh) * 2011-01-21 2011-05-18 郑州大学 一种鹅去氧胆酸的合成方法
ITMI20110534A1 (it) 2011-03-31 2012-10-01 Prodotti Chimici Alimentari "nuovo processo per l'ossidazione selettiva di acidi biliari, loro sali o derivati"
WO2017207648A1 (en) 2016-05-31 2017-12-07 Bionice, S.L.U Process and intermediates for the preparation of obeticholic acid and derivatives thereof
EP3431486A1 (en) 2017-07-18 2019-01-23 Bionice, S.L.U. Process and intermediates for the synthesis of obeticholic acid and derivatives thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4360470A (en) * 1980-10-22 1982-11-23 Hoffmann-La Roche Inc. Process and intermediates for the synthesis of Vitamin D3 metabolites and chenodeoxycholic acid
IT1137459B (it) * 1981-04-14 1986-09-10 Erregierre Spa Prodesso per la preparazione di acido ursodeossicolico ad alta purezza
IT1167478B (it) * 1981-07-24 1987-05-13 Carlo Scolastico Derivati dell'acido ursodesossicolico
FR2511007A1 (fr) * 1981-08-07 1983-02-11 Roussel Uclaf Procede de preparation de l'acide ursodesoxycholique a partir de l'acide 3a, 7b, 12a-trihydroxycholanique et produit intermediaire utilises
JPS5842878B2 (ja) * 1981-12-02 1983-09-22 名糖産業株式会社 １２−オキソコラン酸トシルヒドラゾン化合物、その製法ならびに利用
JPS58155098A (ja) * 1982-03-09 1983-09-14 Yakult Honsha Co Ltd 微生物によるウルソデオキシコ−ル酸の製造法
IT1204429B (it) * 1986-01-09 1989-03-01 Blaschim Spa Riduzione stereoselettiva in acidi biliari

Also Published As

Publication number Publication date
IE903701A1 (en) 1991-04-24
EP0424232A3 (en) 1992-05-20
ES2086388T3 (es) 1996-07-01
IE73449B1 (en) 1997-06-04
ATE134378T1 (de) 1996-03-15
EP0424232B1 (fr) 1996-02-21
EP0424232A2 (fr) 1991-04-24
DE69025449D1 (de) 1996-03-28
DE69025449T2 (de) 1996-07-11
GR3019857T3 (en) 1996-08-31

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