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DE69837945D1 - Tablette, umfassend ein phosphatbindendes Polymer - Google Patents

Tablette, umfassend ein phosphatbindendes Polymer

Info

Publication number
DE69837945D1
DE69837945D1 DE69837945T DE69837945T DE69837945D1 DE 69837945 D1 DE69837945 D1 DE 69837945D1 DE 69837945 T DE69837945 T DE 69837945T DE 69837945 T DE69837945 T DE 69837945T DE 69837945 D1 DE69837945 D1 DE 69837945D1
Authority
DE
Germany
Prior art keywords
phosphate
binding polymer
tablet
particle size
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837945T
Other languages
English (en)
Other versions
DE69837945T2 (de
Inventor
Katsuya Matsuda
Ryuji Kubota
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69837945D1 publication Critical patent/DE69837945D1/de
Publication of DE69837945T2 publication Critical patent/DE69837945T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE69837945T 1997-04-04 1998-04-03 Tablette, umfassend ein phosphatbindendes Polymer Expired - Lifetime DE69837945T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8658197 1997-04-04
JP8658197 1997-04-04

Publications (2)

Publication Number Publication Date
DE69837945D1 true DE69837945D1 (de) 2007-07-26
DE69837945T2 DE69837945T2 (de) 2008-02-21

Family

ID=13890981

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69816082T Expired - Lifetime DE69816082T2 (de) 1997-04-04 1998-04-03 Phosphatbindende polymerzubereitungen
DE69837945T Expired - Lifetime DE69837945T2 (de) 1997-04-04 1998-04-03 Tablette, umfassend ein phosphatbindendes Polymer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69816082T Expired - Lifetime DE69816082T2 (de) 1997-04-04 1998-04-03 Phosphatbindende polymerzubereitungen

Country Status (15)

Country Link
US (2) US6383518B1 (de)
EP (2) EP0997148B1 (de)
JP (2) JP2009173687A (de)
KR (1) KR100456202B1 (de)
CN (1) CN1180782C (de)
AT (2) ATE244013T1 (de)
AU (1) AU726142B2 (de)
CA (1) CA2286003C (de)
CY (1) CY1106823T1 (de)
DE (2) DE69816082T2 (de)
DK (1) DK1304104T3 (de)
ES (2) ES2287215T3 (de)
PT (1) PT1304104E (de)
TW (1) TW592727B (de)
WO (1) WO1998044933A1 (de)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
JP3718341B2 (ja) * 1998-05-12 2005-11-24 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロースとその製造方法
TW568788B (en) 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
EP1239837B1 (de) * 1999-10-19 2005-01-05 Genzyme Corporation Direktkomprimierter tablettenkern auf polymerbasis
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US6680069B1 (en) 1999-11-09 2004-01-20 Shin-Etsu Chemical Co., Ltd. Low-substituted hydroxypropyl cellulose and process for manufacturing the same
JP3552160B2 (ja) 2000-01-14 2004-08-11 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース粒子の形成方法
WO2002066543A1 (en) 2001-02-16 2002-08-29 Genzyme Corporation Method of drying a material having a cohesive phase
CA2444587C (en) 2001-04-18 2008-10-21 Genzyme Corporation Pharmaceutical compositions of low salt polyallylamine hydrochloride
WO2002085379A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for improving vascular access in patients with vascular shunts
WO2002085377A1 (en) 2001-04-18 2002-10-31 Genzyme Corporation Method for lowering serum glucose
FR2827771B1 (fr) * 2001-07-25 2003-10-24 Apis Spheromont Formulation et procede de preparation de spheroides pouvant etre fortement titres et a dispersion rapide
US6600011B2 (en) 2001-10-09 2003-07-29 Genzyme Corporation Process for purification and drying of polymer hydrogels
TWI231760B (en) * 2001-12-20 2005-05-01 Chugai Pharmaceutical Co Ltd Coated lozenge and manufacturing method thereof
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7459502B2 (en) 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7385012B2 (en) * 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7767768B2 (en) 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
JP2008533272A (ja) * 2005-03-16 2008-08-21 ユーエスヴィー リミテッド 架橋ポリアリルアミンポリマーの調製のための改良された方法
EP1951266A2 (de) 2005-09-02 2008-08-06 Genzyme Corporation Verfahren zur entfernung von phosphat und dafür verwendetes polymer
CA2622693C (en) 2005-09-15 2015-05-05 Genzyme Corporation Sachet formulation for amine polymers
GB0601899D0 (en) * 2006-01-31 2006-03-08 Ineos Silicas Ltd Compositions
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
US7749536B2 (en) 2006-02-14 2010-07-06 Teva Pharmaceutical Industries Ltd. Pharmaceutical formulations of aliphatic amine polymers and methods for their manufacture
ES2320265T3 (es) * 2006-02-14 2009-05-20 Teva Pharmaceutical Industries, Ltd. Formulaciones farmaceuticas de polimeros amino alifaticos y procedimientos para su preparacion.
WO2007130463A2 (en) * 2006-05-05 2007-11-15 Genzyme Corporation Amine condensation polymers as phosphate sequestrants
EP2049014A2 (de) * 2006-07-18 2009-04-22 Genzyme Corporation Amindendrimere
CA2749074A1 (en) 2006-09-01 2008-05-29 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
EP2066293A2 (de) 2006-09-29 2009-06-10 Genzyme Corporation Amid-dendrimer-zusammensetzungen
JP2010513271A (ja) * 2006-12-14 2010-04-30 ゲンズイメ コーポレーション アミド−アミンポリマー組成物
EP2114376A1 (de) * 2007-02-23 2009-11-11 Genzyme Corporation Amin-polymerzusammensetzungen
JP2010520285A (ja) * 2007-03-08 2010-06-10 ゲンズイメ コーポレーション スルホンポリマー組成物
WO2008133954A1 (en) * 2007-04-27 2008-11-06 Genzyme Corporation Amido-amine dendrimer compositions
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
WO2009034540A1 (en) * 2007-09-11 2009-03-19 Ranbaxy Laboratories Limited Pharmaceutical composition of sevelamer
GB0720220D0 (en) 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
WO2009078958A1 (en) * 2007-12-14 2009-06-25 Genzyme Corporation Coated pharmaceutical compositions
WO2009154747A1 (en) * 2008-06-20 2009-12-23 Genzyme Corporation Pharmaceutical compositions
DE102008030046A1 (de) 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
WO2010086881A2 (en) 2009-01-22 2010-08-05 Usv Limited Pharmaceutical compositions comprising phosphate-binding polymer
US20100330175A1 (en) * 2009-06-24 2010-12-30 Jobdevairakkam Christopher N Cross-linked polyallylamine tablet core
WO2010149794A2 (en) 2009-06-26 2010-12-29 Combino Pharm, S.L. Novel pharmaceutical composition comprising poly (allylamin-co-n,n'-diallyl- 1,3-diamino-2-hydroxypropane)
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
EP2490675B1 (de) * 2009-10-22 2019-01-23 Synthon B.V. Pharmazeutische zusammensetzung enthaltend sevelamer
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
EP2545907A1 (de) 2011-07-15 2013-01-16 Combino Pharm, S.L. Verfahren zur wässrig-nassen Granulation für vernetzte Polyallylaminpolymere
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
US20180015119A1 (en) * 2015-02-23 2018-01-18 Amneal Pharmaceuticals Company Gmbh Process for granulating sevelamer carbonate
MX2019007904A (es) 2016-12-28 2019-09-09 Fujifilm Corp Emulsion de polimero que contiene atomo de nitrogeno o la sal del mismo, metodo de produccion para el mismo y metodo de produccion para las particulas.
JP7018451B2 (ja) * 2017-10-16 2022-02-10 富士フイルム株式会社 高リン血症治療剤および粒子
WO2019078197A1 (ja) 2017-10-16 2019-04-25 富士フイルム株式会社 高リン血症治療剤
JP2019182818A (ja) * 2018-04-17 2019-10-24 ライオン株式会社 舌苔除去用の口腔内崩壊錠及び舌苔除去方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6090243A (ja) 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4631305A (en) 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
ES2039226T3 (es) 1986-12-30 1993-09-16 American Cyanamid Company Procedimiento para preparar composiciones que contienen policarbofil.
US4956182A (en) * 1989-03-16 1990-09-11 Bristol-Myers Company Direct compression cholestyramine tablet and solvent-free coating therefor
JPH02286621A (ja) 1989-04-26 1990-11-26 Mitsubishi Kasei Corp 経口コレステロール低下剤
JPH0413627A (ja) 1990-04-27 1992-01-17 Mitsubishi Kasei Corp 経口コレステロール低下剤
JP2609022B2 (ja) 1990-11-29 1997-05-14 北陸製薬株式会社 ポリカルボフィルカルシウム含有製剤
JPH06157325A (ja) 1992-11-30 1994-06-03 Mitsubishi Kasei Corp 経口コレステロール低下剤
TW272942B (de) 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5496545A (en) 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
WO1996021454A1 (en) * 1995-01-12 1996-07-18 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
JP3836893B2 (ja) 1995-01-24 2006-10-25 アボットジャパン株式会社 ポリカルボフィルカルシウム含有製剤
TW438608B (en) 1995-08-02 2001-06-07 Hisamitsu Pharmaceutical Co A tablet containing anion exchange resin
JP3389493B2 (ja) * 1997-04-04 2003-03-24 中外製薬株式会社 リン酸結合性ポリマー製剤

Also Published As

Publication number Publication date
DE69837945T2 (de) 2008-02-21
ES2201463T3 (es) 2004-03-16
TW592727B (en) 2004-06-21
HK1055387A1 (en) 2004-01-09
AU6522398A (en) 1998-10-30
ATE364377T1 (de) 2007-07-15
JP2009173687A (ja) 2009-08-06
JP5681156B2 (ja) 2015-03-04
EP0997148A1 (de) 2000-05-03
PT1304104E (pt) 2007-07-27
US20020122786A1 (en) 2002-09-05
CN1254287A (zh) 2000-05-24
CY1106823T1 (el) 2012-05-23
EP1304104A2 (de) 2003-04-23
CA2286003C (en) 2007-06-05
ATE244013T1 (de) 2003-07-15
EP1304104A3 (de) 2003-11-12
AU726142B2 (en) 2000-11-02
DE69816082T2 (de) 2004-04-15
US6383518B1 (en) 2002-05-07
HK1027506A1 (en) 2001-01-19
DK1304104T3 (da) 2007-07-16
KR100456202B1 (ko) 2004-11-09
US6696087B2 (en) 2004-02-24
EP1304104B1 (de) 2007-06-13
WO1998044933A1 (fr) 1998-10-15
JP2013010803A (ja) 2013-01-17
CN1180782C (zh) 2004-12-22
EP0997148B1 (de) 2003-07-02
CA2286003A1 (en) 1998-10-15
DE69816082D1 (de) 2003-08-07
ES2287215T3 (es) 2007-12-16
KR20010005980A (ko) 2001-01-15
EP0997148A4 (de) 2000-05-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition