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DE69626510D1 - Verwendung des leukämie-inhibitor-faktor und endothelin antagonisten - Google Patents

Verwendung des leukämie-inhibitor-faktor und endothelin antagonisten

Info

Publication number
DE69626510D1
DE69626510D1 DE69626510T DE69626510T DE69626510D1 DE 69626510 D1 DE69626510 D1 DE 69626510D1 DE 69626510 T DE69626510 T DE 69626510T DE 69626510 T DE69626510 T DE 69626510T DE 69626510 D1 DE69626510 D1 DE 69626510D1
Authority
DE
Germany
Prior art keywords
endothelin antagonists
inhibitor factor
leukemia inhibitor
antagonist
endothelin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69626510T
Other languages
English (en)
Other versions
DE69626510T2 (de
Inventor
Napoleone Ferrara
Kathleen King
A Luis
P Mather
F Paoni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DE69626510D1 publication Critical patent/DE69626510D1/de
Application granted granted Critical
Publication of DE69626510T2 publication Critical patent/DE69626510T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69626510T 1995-04-24 1996-04-17 Verwendung des leukämie-inhibitor-faktor und endothelin antagonisten Expired - Lifetime DE69626510T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42738395A 1995-04-24 1995-04-24
PCT/US1996/005498 WO1996033740A1 (en) 1995-04-24 1996-04-17 Use of leukemia inhibitory factor and endothelin antagonists

Publications (2)

Publication Number Publication Date
DE69626510D1 true DE69626510D1 (de) 2003-04-10
DE69626510T2 DE69626510T2 (de) 2003-12-11

Family

ID=23694642

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69626510T Expired - Lifetime DE69626510T2 (de) 1995-04-24 1996-04-17 Verwendung des leukämie-inhibitor-faktor und endothelin antagonisten
DE69635630T Expired - Lifetime DE69635630T2 (de) 1995-04-24 1996-04-17 Verwendung eines Leukämie-hemmenden Faktor Antagonisten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69635630T Expired - Lifetime DE69635630T2 (de) 1995-04-24 1996-04-17 Verwendung eines Leukämie-hemmenden Faktor Antagonisten

Country Status (12)

Country Link
EP (2) EP1287832B1 (de)
JP (1) JPH11504332A (de)
AT (2) ATE313333T1 (de)
AU (1) AU702375B2 (de)
CA (1) CA2214636C (de)
DE (2) DE69626510T2 (de)
DK (2) DK0830143T3 (de)
ES (1) ES2254564T3 (de)
IL (1) IL117998A (de)
MX (1) MX9707939A (de)
WO (1) WO1996033740A1 (de)
ZA (1) ZA963274B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU753197B2 (en) 1998-07-06 2002-10-10 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Compositions and methods for in vitro fertilization
EP1549198A4 (de) * 2002-09-30 2007-03-28 Univ Duke Thymusatrophi
JP2011231014A (ja) * 2008-08-27 2011-11-17 Keiichi Fukuda 心不全の治療剤
EP2371860A1 (de) * 2010-04-05 2011-10-05 Fundació Privada Institut d'Investigació Oncològica de Vall d'Hebron Den humanen leukaemieinhibierenden Faktor (LIF) erkennender Antikörper und Verwendung von LIF-Antikörpern bei der Behandlung von Krankheiten im Zusammenhang mit ungewollter Zellproliferation
US10583191B2 (en) 2016-12-19 2020-03-10 Mosaic Biomedicals Slu Antibodies against LIF and uses thereof
CN118652335A (zh) 2016-12-19 2024-09-17 免疫医疗有限公司 抗lif抗体及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023556A1 (en) * 1992-05-08 1993-11-25 Genentech, Inc. Antibodies to leukemia inhibitory factor
WO1995008550A1 (en) * 1993-09-24 1995-03-30 Abbott Laboratories Endothelin antagonists

Also Published As

Publication number Publication date
DK0830143T3 (da) 2003-06-16
EP1287832A2 (de) 2003-03-05
ZA963274B (en) 1997-10-24
EP0830143A1 (de) 1998-03-25
AU5665896A (en) 1996-11-18
CA2214636C (en) 2009-12-22
IL117998A0 (en) 1996-08-04
JPH11504332A (ja) 1999-04-20
ATE313333T1 (de) 2006-01-15
ES2254564T3 (es) 2006-06-16
DE69626510T2 (de) 2003-12-11
DE69635630T2 (de) 2006-08-10
DK1287832T3 (da) 2006-05-01
CA2214636A1 (en) 1996-10-31
EP0830143B1 (de) 2003-03-05
MX9707939A (es) 1997-12-31
ATE233570T1 (de) 2003-03-15
IL117998A (en) 2001-04-30
AU702375B2 (en) 1999-02-18
EP1287832A3 (de) 2003-04-16
WO1996033740A1 (en) 1996-10-31
DE69635630D1 (de) 2006-01-26
EP1287832B1 (de) 2005-12-21

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Legal Events

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8364 No opposition during term of opposition