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DE69430919D1 - Eine phosphoenolpyruvat-carboxylasevariante, ihr gen und verfahren zur herstellung von aminosäuren - Google Patents

Eine phosphoenolpyruvat-carboxylasevariante, ihr gen und verfahren zur herstellung von aminosäuren

Info

Publication number
DE69430919D1
DE69430919D1 DE69430919T DE69430919T DE69430919D1 DE 69430919 D1 DE69430919 D1 DE 69430919D1 DE 69430919 T DE69430919 T DE 69430919T DE 69430919 T DE69430919 T DE 69430919T DE 69430919 D1 DE69430919 D1 DE 69430919D1
Authority
DE
Germany
Prior art keywords
gene
phosphoenolpyruvate carboxylase
production
amino acids
carboxylase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69430919T
Other languages
English (en)
Other versions
DE69430919T2 (de
Inventor
Masakazu Sugimoto
Tomoko Suzuki
Hiroshi Matsui
Katsura Izui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27320552&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69430919(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of DE69430919D1 publication Critical patent/DE69430919D1/de
Application granted granted Critical
Publication of DE69430919T2 publication Critical patent/DE69430919T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69430919T 1993-08-24 1994-08-17 Eine phosphoenolpyruvat-carboxylasevariante, ihr gen und verfahren zur herstellung von aminosäuren Expired - Lifetime DE69430919T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP20977693 1993-08-24
JP20977593 1993-08-24
JP15387694 1994-07-05
PCT/JP1994/001365 WO1995006114A1 (fr) 1993-08-24 1994-08-17 Allele de phosphenolpyruvate carboxylase, gene de cet allele et procede de production de l'acide amine

Publications (2)

Publication Number Publication Date
DE69430919D1 true DE69430919D1 (de) 2002-08-08
DE69430919T2 DE69430919T2 (de) 2003-02-27

Family

ID=27320552

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69430919T Expired - Lifetime DE69430919T2 (de) 1993-08-24 1994-08-17 Eine phosphoenolpyruvat-carboxylasevariante, ihr gen und verfahren zur herstellung von aminosäuren

Country Status (15)

Country Link
US (2) US5876983A (de)
EP (1) EP0723011B1 (de)
KR (2) KR100337959B1 (de)
CN (1) CN1179043C (de)
AT (1) ATE220099T1 (de)
AU (1) AU682547B2 (de)
BR (1) BR9407625A (de)
CA (1) CA2169170C (de)
CZ (1) CZ289051B6 (de)
DE (1) DE69430919T2 (de)
HU (1) HU219600B (de)
MY (1) MY112250A (de)
PL (1) PL181380B1 (de)
SK (1) SK283369B6 (de)
WO (1) WO1995006114A1 (de)

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MXPA01013445A (es) * 1999-06-29 2002-07-30 Archer Daniels Midland Co Regulacion de la asimilacion de carbono.
US6599732B1 (en) * 1999-06-29 2003-07-29 Archer-Daniels-Midland Company Regulation of carbon assimilation
DE60027161D1 (de) 1999-07-02 2006-05-18 Ajinomoto Kk Für das saccharose-pts-enzym ii kodierende dna
DE19931314A1 (de) * 1999-07-07 2001-01-11 Degussa L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von Lysin
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US6727411B2 (en) 1999-12-13 2004-04-27 Ajinomoto Co., Inc. Method of producing transgenic plants having improved amino acid composition
BR0016656A (pt) * 1999-12-24 2002-11-05 Ajinomoto Kk Bactéria corineforme, método para produzir um l-aminoácido, e, dna
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
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US7368266B2 (en) 2001-02-13 2008-05-06 Cj Corporation Method for L-threonine production
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US20030115638A1 (en) * 2001-08-17 2003-06-19 Ajinomoto Co., Inc. Plants having increased amino acids content and methods for producing the same
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JP2007532114A (ja) * 2004-04-09 2007-11-15 ジェネンコー・インターナショナル・インク バチルスにおけるｐｃｋＡ修飾および増強されたタンパク質発現
KR100768748B1 (ko) 2004-12-30 2007-10-19 씨제이 주식회사 외래의 ｎａｄｐ 의존적 글리세르알데히드-3-포스페이트디히드로게나제 유전자를 포함하는 에세리키아 종 또는코리네박리움 종 미생물 및 그를 이용하여 ｌ-라이신을생산하는 방법
WO2007017710A1 (en) 2005-08-11 2007-02-15 Metabolic Explorer Process for the preparation of aspartate and derived amino acids like lysine, threonine, isoleucine, methionine, homoserine, or valine employing a microorganism with enhanced isocitrate lyase and/or malate synthase expression
EP1979486B1 (de) 2006-01-30 2013-04-17 Ajinomoto Co., Inc. L-aminosäure-produzierendes bakterium und verfahren zur herstellung von l-aminosäure
JP2009118740A (ja) 2006-03-03 2009-06-04 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
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WO2015050234A1 (ja) 2013-10-02 2015-04-09 味の素株式会社 アンモニア制御装置およびアンモニア制御方法
JP6459962B2 (ja) 2013-10-21 2019-01-30 味の素株式会社 Ｌ−アミノ酸の製造法
BR112016008830B1 (pt) 2013-10-23 2023-02-23 Ajinomoto Co., Inc Método para produzir uma substância alvo
EP2993228B1 (de) 2014-09-02 2019-10-09 Cargill, Incorporated Herstellung von fettsäureestern
CN105132388B (zh) * 2015-09-06 2018-02-23 江南大学 一种酶活性提高的丙酮酸羧化酶突变体r485p及其应用
CN105907730B (zh) * 2016-05-11 2019-06-21 江南大学 一种酶活性提高的丙酮酸羧化酶突变体n1078f及其应用
JP2020506702A (ja) 2017-02-02 2020-03-05 カーギル インコーポレイテッド Ｃ６−ｃ１０脂肪酸誘導体を生成する遺伝子組み換え細胞
CN111094571B (zh) * 2017-09-01 2023-10-27 国立大学法人新潟大学 龙涎香醇的有效制备方法
WO2022133917A1 (zh) * 2020-12-24 2022-06-30 武汉远大弘元股份有限公司 改造的磷酸烯醇丙酮酸羧化酶及其在提高谷氨酸棒杆菌氨基酸产量中的应用
CN115806962A (zh) * 2021-09-15 2023-03-17 中国科学院天津工业生物技术研究所 磷酸烯醇式丙酮酸羧化酶突变体及其应用

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JPH07108228B2 (ja) * 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド

Also Published As

Publication number Publication date
HU219600B (hu) 2001-05-28
HUT73690A (en) 1996-09-30
SK283369B6 (sk) 2003-06-03
PL313119A1 (en) 1996-06-10
WO1995006114A1 (fr) 1995-03-02
PL181380B1 (pl) 2001-07-31
BR9407625A (pt) 1997-01-21
KR960704029A (ko) 1996-08-31
EP0723011A4 (de) 1996-05-21
AU8099194A (en) 1995-03-21
CA2169170A1 (en) 1995-03-02
CZ52496A3 (en) 1996-06-12
ATE220099T1 (de) 2002-07-15
EP0723011A1 (de) 1996-07-24
CN1179043C (zh) 2004-12-08
US5919694A (en) 1999-07-06
CZ289051B6 (cs) 2001-10-17
KR100337959B1 (ko) 2002-11-23
CA2169170C (en) 2007-01-09
HU9600240D0 (en) 1996-03-28
SK20496A3 (en) 1996-11-06
EP0723011B1 (de) 2002-07-03
AU682547B2 (en) 1997-10-09
CN1133615A (zh) 1996-10-16
MY112250A (en) 2001-05-31
US5876983A (en) 1999-03-02
DE69430919T2 (de) 2003-02-27

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