DE602004004677D1 - Verfahren zur herstellung substituierter 5-amino-pyrazolo-ä4,3-eü-1,2,4-triazoloä1,5-cüpyrimidine - Google Patents

Verfahren zur herstellung substituierter 5-amino-pyrazolo-ä4,3-eü-1,2,4-triazoloä1,5-cüpyrimidine

Info

Publication number: DE602004004677D1
Authority: DE; Germany
Prior art keywords: cüpyrimidine; pyrazolo; amino; preparing substituted; substituted
Prior art date: 2003-10-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE602004004677T

Other languages

English (en)

Other versions

DE602004004677T2 (de

Inventor

Shen-Chun Kuo

Jieh-Shyh Tsai

Thanh Tran

Pengyi Zhang

D Jones

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Sharp and Dohme LLC

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-28

Filing date

2004-10-26

Publication date

2007-03-22

2004-10-26 Application filed by Schering Corp filed Critical Schering Corp

2007-03-22 Publication of DE602004004677D1 publication Critical patent/DE602004004677D1/de

2007-11-15 Application granted granted Critical

2007-11-15 Publication of DE602004004677T2 publication Critical patent/DE602004004677T2/de

2024-10-27 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DE602004004677T 2003-10-28 2004-10-26 Verfahren zur Herstellung substituierter 5-Amino-Pyrazolo-(4,3-E)-1,2,4-Triazo lo (1,5-C)Pyrimidine Expired - Lifetime DE602004004677T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US51505103P	2003-10-28	2003-10-28
US515051P		2003-10-28
PCT/US2004/035472 WO2005044819A1 (en)	2003-10-28	2004-10-26	Process for preparing substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines

Publications (2)

Publication Number	Publication Date
DE602004004677D1 true DE602004004677D1 (de)	2007-03-22
DE602004004677T2 DE602004004677T2 (de)	2007-11-15

Family

ID=34572798

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE602004004677T Expired - Lifetime DE602004004677T2 (de)	2003-10-28	2004-10-26	Verfahren zur Herstellung substituierter 5-Amino-Pyrazolo-(4,3-E)-1,2,4-Triazo lo (1,5-C)Pyrimidine

Country Status (19)

Country	Link
US (4)	US7223861B2 (de)
EP (1)	EP1678182B1 (de)
JP (2)	JP4782693B2 (de)
CN (2)	CN101899050A (de)
AR (1)	AR046560A1 (de)
AT (1)	ATE353331T1 (de)
CA (1)	CA2543431A1 (de)
CY (1)	CY1106393T1 (de)
DE (1)	DE602004004677T2 (de)
DK (1)	DK1678182T3 (de)
ES (1)	ES2278353T3 (de)
HK (1)	HK1086008A1 (de)
HR (1)	HRP20070063T3 (de)
MX (1)	MXPA06004722A (de)
PL (1)	PL1678182T3 (de)
PT (1)	PT1678182E (de)
SI (1)	SI1678182T1 (de)
WO (1)	WO2005044819A1 (de)
ZA (1)	ZA200603307B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI288137B (en) *	2000-05-26	2007-10-11	Schering Corp	Adenosine A2a receptor antagonists
DE602004004677T2 (de) *	2003-10-28	2007-11-15	Schering Corp.	Verfahren zur Herstellung substituierter 5-Amino-Pyrazolo-(4,3-E)-1,2,4-Triazo lo (1,5-C)Pyrimidine
ATE556712T1 (de) *	2005-06-07	2012-05-15	Kyowa Hakko Kirin Co Ltd	A2a antagonisten zur behandlung von motorischen störungen
US8598343B2 (en) *	2009-08-07	2013-12-03	Merck Sharp & Dohme Corp.	Process for preparing a 2-alkynyl substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
US20110144049A1 (en) *	2009-10-21	2011-06-16	Serebruany Victor L	Treating Cardiac Arrhythmias, Heart Failure, Peripheral Artery Disease and Stroke with Cyclopentyl-Triazolo-Pyrimidine or Derivative Thereof
WO2013024474A1 (en) *	2011-08-18	2013-02-21	Mapi Phrarma Ltd.	Polymorphs of preladenant
JPWO2013168196A1 (ja)	2012-05-10	2015-12-24	ユニテクノ株式会社	半導体搬送テスト治具
AR102088A1 (es) *	2014-09-26	2017-02-01	Genentech Inc	Procesos para preparar compuestos de (ciclopentil[d]pirimidin-4-il)piperazina
WO2020112700A1 (en)	2018-11-30	2020-06-04	Merck Sharp & Dohme Corp.	9-substituted amino triazolo quinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and their use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4039733A1 (de) *	1990-12-13	1992-06-17	Basf Ag	Substituierte 5-aminopyrazole
IT1264901B1 (it) *	1993-06-29	1996-10-17	Schering Plough S P A	Analoghi eterociclici di 1,2,4-triazolo(15-c)pirimidine ad attivita' antagonista per il recettore a2 dell'adenosina
US6448253B1 (en)	1998-09-16	2002-09-10	King Pharmaceuticals Research And Development, Inc.	Adenosine A3 receptor modulators
TWI288137B (en)	2000-05-26	2007-10-11	Schering Corp	Adenosine A2a receptor antagonists
CN1491227A (zh) *	2001-02-05	2004-04-21	株式会社大V制药工厂	三唑并喹唑啉和吡唑并三唑并嘧啶衍生物、医药组合物、腺苷 a 3受体亲和剂、降眼压剂、预防和治疗青光眼的制剂及降低眼压的方法
US7179801B2 (en) *	2001-05-01	2007-02-20	Astellas Pharma Inc.	Cephem compounds
ES2336435T3 (es) *	2001-11-30	2010-04-13	Schering Corporation	Antagonista del receptor de adenosina a2a.
DE602004004677T2 (de) *	2003-10-28	2007-11-15	Schering Corp.	Verfahren zur Herstellung substituierter 5-Amino-Pyrazolo-(4,3-E)-1,2,4-Triazo lo (1,5-C)Pyrimidine
ATE377599T1 (de) *	2003-12-01	2007-11-15	Schering Corp	Verfahren zur herstellung von substituierten 5- aminopyrazolo(4,3-e)-1,2,4-triazolo(1,5- c)pyrimidinen

2004
- 2004-10-26 DE DE602004004677T patent/DE602004004677T2/de not_active Expired - Lifetime
- 2004-10-26 US US10/973,631 patent/US7223861B2/en active Active
- 2004-10-26 EP EP04796445A patent/EP1678182B1/de not_active Expired - Lifetime
- 2004-10-26 SI SI200430198T patent/SI1678182T1/sl unknown
- 2004-10-26 PL PL04796445T patent/PL1678182T3/pl unknown
- 2004-10-26 CN CN2010101611983A patent/CN101899050A/zh active Pending
- 2004-10-26 AT AT04796445T patent/ATE353331T1/de active
- 2004-10-26 ES ES04796445T patent/ES2278353T3/es not_active Expired - Lifetime
- 2004-10-26 DK DK04796445T patent/DK1678182T3/da active
- 2004-10-26 MX MXPA06004722A patent/MXPA06004722A/es active IP Right Grant
- 2004-10-26 PT PT04796445T patent/PT1678182E/pt unknown
- 2004-10-26 CA CA002543431A patent/CA2543431A1/en not_active Abandoned
- 2004-10-26 WO PCT/US2004/035472 patent/WO2005044819A1/en active IP Right Grant
- 2004-10-26 CN CN200480039044XA patent/CN1898246B/zh not_active Expired - Fee Related
- 2004-10-26 JP JP2006538174A patent/JP4782693B2/ja not_active Expired - Fee Related
- 2004-10-27 AR ARP040103912A patent/AR046560A1/es not_active Application Discontinuation
2006
- 2006-04-25 ZA ZA200603307A patent/ZA200603307B/en unknown
- 2006-07-20 HK HK06108129A patent/HK1086008A1/xx not_active IP Right Cessation
2007
- 2007-02-19 HR HR20070063T patent/HRP20070063T3/xx unknown
- 2007-03-16 CY CY20071100375T patent/CY1106393T1/el unknown
- 2007-04-20 US US11/788,682 patent/US7439361B2/en not_active Expired - Lifetime
2008
- 2008-09-11 US US12/208,717 patent/US7601833B2/en not_active Expired - Lifetime
2009
- 2009-09-02 US US12/552,765 patent/US20090326241A1/en not_active Abandoned
2011
- 2011-03-22 JP JP2011063381A patent/JP2011116795A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
SI1678182T1 (sl)	2007-06-30
ZA200603307B (en)	2008-07-30
US7439361B2 (en)	2008-10-21
PL1678182T3 (pl)	2007-05-31
JP4782693B2 (ja)	2011-09-28
US7601833B2 (en)	2009-10-13
MXPA06004722A (es)	2006-07-05
DK1678182T3 (da)	2007-06-04
HK1086008A1 (en)	2006-09-08
CY1106393T1 (el)	2011-10-12
US20070203340A1 (en)	2007-08-30
CN1898246A (zh)	2007-01-17
US20050090492A1 (en)	2005-04-28
EP1678182A1 (de)	2006-07-12
EP1678182B1 (de)	2007-02-07
PT1678182E (pt)	2007-04-30
US7223861B2 (en)	2007-05-29
DE602004004677T2 (de)	2007-11-15
JP2011116795A (ja)	2011-06-16
JP2007509948A (ja)	2007-04-19
AR046560A1 (es)	2005-12-14
CN101899050A (zh)	2010-12-01
CA2543431A1 (en)	2005-05-19
US20090005559A1 (en)	2009-01-01
US20090326241A1 (en)	2009-12-31
CN1898246B (zh)	2010-10-27
ES2278353T3 (es)	2007-08-01
ATE353331T1 (de)	2007-02-15
HRP20070063T3 (en)	2007-04-30
WO2005044819A1 (en)	2005-05-19

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Legal Events

Date	Code	Title	Description
2008-03-06	8364	No opposition during term of opposition