DE60015496D1 - Verfahren zur herstellung von 3-substituierte 1,5-diarylpyrozole - Google Patents

Verfahren zur herstellung von 3-substituierte 1,5-diarylpyrozole

Info

Publication number: DE60015496D1
Authority: DE; Germany
Prior art keywords: diarylpyrozoles; substituted; producing
Prior art date: 1999-08-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60015496T

Other languages

English (en)

Other versions

DE60015496T2 (de

Inventor

F Abdel-Magid

D Harris

A Maryanoff

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Janssen Pharmaceuticals Inc

Original Assignee

Ortho McNeil Pharmaceutical Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-03

Filing date

2000-08-01

Publication date

2004-12-09

2000-08-01 Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc

2004-12-09 Application granted granted Critical

2004-12-09 Publication of DE60015496D1 publication Critical patent/DE60015496D1/de

2005-10-27 Publication of DE60015496T2 publication Critical patent/DE60015496T2/de

2020-08-02 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/083—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid anhydrides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/88—Unsaturated compounds containing keto groups containing halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DE60015496T 1999-08-03 2000-08-01 Verfahren zur herstellung von 3-substituierte 1,5-diarylpyrozole Expired - Lifetime DE60015496T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US14699799P	1999-08-03	1999-08-03
US146997P		1999-08-03
PCT/US2000/020917 WO2001009102A2 (en)	1999-08-03	2000-08-01	Process for preparing 1,5-diaryl-3-substituted pyrazoles

Publications (2)

Publication Number	Publication Date
DE60015496D1 true DE60015496D1 (de)	2004-12-09
DE60015496T2 DE60015496T2 (de)	2005-10-27

Family

ID=22519936

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DE60015496T Expired - Lifetime DE60015496T2 (de)	1999-08-03	2000-08-01	Verfahren zur herstellung von 3-substituierte 1,5-diarylpyrozole
DE60031315T Expired - Lifetime DE60031315T2 (de)	1999-08-03	2000-08-01	Verfahren zur Herstellung von Derivaten von i(1,5-Diaryl)pyrazol-3-ylöpropansäure

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DE60031315T Expired - Lifetime DE60031315T2 (de)	1999-08-03	2000-08-01	Verfahren zur Herstellung von Derivaten von i(1,5-Diaryl)pyrazol-3-ylöpropansäure

Country Status (26)

Country	Link
US (4)	US6384233B1 (de)
EP (2)	EP1413575B1 (de)
JP (2)	JP4886951B2 (de)
KR (1)	KR100646883B1 (de)
CN (1)	CN1219771C (de)
AR (1)	AR032589A1 (de)
AT (2)	ATE342254T1 (de)
AU (2)	AU779353B2 (de)
BR (1)	BR0006978B1 (de)
CA (2)	CA2636755C (de)
CZ (2)	CZ299710B6 (de)
DE (2)	DE60015496T2 (de)
DK (1)	DK1413575T3 (de)
ES (2)	ES2274171T3 (de)
HK (1)	HK1040081B (de)
HU (1)	HU228678B1 (de)
IL (2)	IL142341A0 (de)
MY (1)	MY122496A (de)
NO (1)	NO318467B1 (de)
NZ (1)	NZ510890A (de)
PL (1)	PL201799B1 (de)
PT (2)	PT1413575E (de)
RU (1)	RU2243967C2 (de)
TW (1)	TWI234562B (de)
WO (1)	WO2001009102A2 (de)
ZA (1)	ZA200103533B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1413575B1 (de) *	1999-08-03	2006-10-11	Ortho-McNeil Pharmaceutical, Inc.	Verfahren zur Herstellung von Derivaten von ¬(1,5-Diaryl)pyrazol-3-yl\|propansäure
WO2004089303A2 (en) *	2003-04-03	2004-10-21	Merck & Co., Inc.	Di-aryl substituted pyrazole modulators of metabotropic glutamate receptor-5
WO2005019523A2 (en) *	2003-08-19	2005-03-03	Day-Glo Color Corp.	Polymeric colorants and method of coloring thermoplastic resins
EP2805957A1 (de)	2013-05-23	2014-11-26	hameln rds gmbh	Kristalline Formen von Trinatrium-Zink-Diethylen-triaminpentaessigsäure
CN111018785B (zh) *	2019-12-26	2022-02-11	武汉科技大学	一种1-（4-氯苯基）-3-吡唑醇的合成方法及应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4826868A (en) *	1986-05-29	1989-05-02	Ortho Pharmaceutical Corporation	1,5-Diaryl-3-substituted pyrazoles pharmaceutical compositions and use
US5164381A (en)	1986-05-29	1992-11-17	Ortho Pharmaceutical Corporation	Pharmacologically active 1,5-diaryl-3-substituted pyrazoles and method for synthesizing the same
US5078780A (en)	1986-10-22	1992-01-07	Ciba-Geigy Corporation	1,5-diphenylpyrazole-3-carboxylic acid derivatives for the protection of cultivated plants
US4808613A (en) *	1986-11-21	1989-02-28	Bristol-Myers Company	Rebeccamycin derivative containing pharmaceutical composition
US4898952A (en) *	1987-05-29	1990-02-06	Ortho Pharmaceutical Corporation	Regioselective synthesis of a 1,5-disubstituted pyrazole
JPH0699382B2 (ja) *	1987-06-17	1994-12-07	富士写真フイルム株式会社	Ｎ−メチル−α−ジアルキルアミノアセトヒドロキサム酸誘導体
US5130421A (en) *	1988-03-24	1992-07-14	Bristol-Myers Company	Production of 2',3'-dideoxy-2',3'-didehydronucleosides
US4896952A (en) *	1988-04-22	1990-01-30	International Business Machines Corporation	Thin film beamsplitter optical element for use in an image-forming lens system
US5154381A (en) *	1988-12-02	1992-10-13	Malinao Michael M	Microphone boom holder
US5032588A (en) *	1989-12-08	1991-07-16	Abbott Laboratories	Thiazole lipoxygenase-inhibiting compounds derived from non-steroidal antiinflammatory carboxylic acids
US5117054A (en)	1991-09-26	1992-05-26	Ortho Pharmaceutical Corporation	N-hydroxy, N-methyl propanamides
FR2692575B1 (fr)	1992-06-23	1995-06-30	Sanofi Elf	Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5387602A (en)	1993-08-30	1995-02-07	Ortho Pharmaceutical Corporation	1.5-diphenyl-3-(N-hydroxycarbamoyloxyalkyl)pyrazoles
US5412151A (en) *	1993-10-22	1995-05-02	Eastman Chemical Company	Thermosetting coating compositions
JPH0944014A (ja) *	1995-08-03	1997-02-14	Canon Inc	加熱用フィルム、加熱加圧部材、加熱装置及び画像形成装置
US5843958A (en) *	1996-11-27	1998-12-01	Ortho Pharmaceutical Corporation	Arylpyrazoles as leukotriene inhibitors
EP1413575B1 (de) *	1999-08-03	2006-10-11	Ortho-McNeil Pharmaceutical, Inc.	Verfahren zur Herstellung von Derivaten von ¬(1,5-Diaryl)pyrazol-3-yl\|propansäure

2000
- 2000-08-01 EP EP03078588A patent/EP1413575B1/de not_active Expired - Lifetime
- 2000-08-01 HU HU0103778A patent/HU228678B1/hu unknown
- 2000-08-01 IL IL14234100A patent/IL142341A0/xx unknown
- 2000-08-01 JP JP2001514305A patent/JP4886951B2/ja not_active Expired - Lifetime
- 2000-08-01 CZ CZ20011202A patent/CZ299710B6/cs not_active IP Right Cessation
- 2000-08-01 PT PT03078588T patent/PT1413575E/pt unknown
- 2000-08-01 ES ES03078588T patent/ES2274171T3/es not_active Expired - Lifetime
- 2000-08-01 EP EP00955303A patent/EP1144382B1/de not_active Expired - Lifetime
- 2000-08-01 WO PCT/US2000/020917 patent/WO2001009102A2/en active Application Filing
- 2000-08-01 CA CA2636755A patent/CA2636755C/en not_active Expired - Lifetime
- 2000-08-01 AT AT03078588T patent/ATE342254T1/de active
- 2000-08-01 PT PT00955303T patent/PT1144382E/pt unknown
- 2000-08-01 DE DE60015496T patent/DE60015496T2/de not_active Expired - Lifetime
- 2000-08-01 CA CA002346142A patent/CA2346142C/en not_active Expired - Lifetime
- 2000-08-01 CN CNB008021058A patent/CN1219771C/zh not_active Expired - Lifetime
- 2000-08-01 KR KR1020017004245A patent/KR100646883B1/ko active IP Right Grant
- 2000-08-01 ES ES00955303T patent/ES2232482T3/es not_active Expired - Lifetime
- 2000-08-01 AT AT00955303T patent/ATE281437T1/de active
- 2000-08-01 AU AU67526/00A patent/AU779353B2/en not_active Expired
- 2000-08-01 BR BRPI0006978-7A patent/BR0006978B1/pt not_active IP Right Cessation
- 2000-08-01 DE DE60031315T patent/DE60031315T2/de not_active Expired - Lifetime
- 2000-08-01 PL PL347025A patent/PL201799B1/pl unknown
- 2000-08-01 CZ CZ20060485A patent/CZ299711B6/cs not_active IP Right Cessation
- 2000-08-01 NZ NZ510890A patent/NZ510890A/en not_active IP Right Cessation
- 2000-08-01 DK DK03078588T patent/DK1413575T3/da active
- 2000-08-01 RU RU2001109261/04A patent/RU2243967C2/ru active
- 2000-08-02 MY MYPI20003528A patent/MY122496A/en unknown
- 2000-08-02 AR ARP000103984A patent/AR032589A1/es active IP Right Grant
- 2000-09-25 TW TW089115548A patent/TWI234562B/zh not_active IP Right Cessation
2001
- 2001-04-02 NO NO20011652A patent/NO318467B1/no not_active IP Right Cessation
- 2001-05-02 ZA ZA200103533A patent/ZA200103533B/en unknown
- 2001-09-28 US US09/966,116 patent/US6384233B1/en not_active Expired - Lifetime
2002
- 2002-03-01 US US10/086,583 patent/US6613914B2/en not_active Expired - Lifetime
- 2002-03-05 HK HK02101683.8A patent/HK1040081B/zh not_active IP Right Cessation
2003
- 2003-06-12 US US10/460,601 patent/US6953860B2/en not_active Expired - Lifetime
2005
- 2005-04-20 AU AU2005201660A patent/AU2005201660A1/en not_active Withdrawn
- 2005-08-30 US US11/215,329 patent/US7247745B2/en not_active Expired - Lifetime
- 2005-11-01 IL IL171712A patent/IL171712A/en active IP Right Grant
2011
- 2011-10-24 JP JP2011233200A patent/JP2012051929A/ja active Pending

Also Published As

Publication number	Publication date
NO20011652L (no)	2001-05-23
JP2003506359A (ja)	2003-02-18
HUP0103778A3 (en)	2002-07-29
CZ20011202A3 (cs)	2001-09-12
AR032589A1 (es)	2003-11-19
CN1219771C (zh)	2005-09-21
DK1413575T3 (da)	2006-12-27
CA2636755C (en)	2010-10-19
ZA200103533B (en)	2002-05-02
CZ299711B6 (cs)	2008-10-29
ES2232482T3 (es)	2005-06-01
BR0006978B1 (pt)	2010-11-30
EP1144382A2 (de)	2001-10-17
EP1413575A2 (de)	2004-04-28
NZ510890A (en)	2003-09-26
WO2001009102A2 (en)	2001-02-08
US20020128487A1 (en)	2002-09-12
US6384233B1 (en)	2002-05-07
EP1413575A3 (de)	2004-10-06
DE60031315D1 (de)	2006-11-23
EP1413575B1 (de)	2006-10-11
PT1144382E (pt)	2005-02-28
EP1144382A3 (de)	2002-09-11
AU779353B2 (en)	2005-01-20
IL171712A (en)	2010-04-29
RU2243967C2 (ru)	2005-01-10
US20040230060A1 (en)	2004-11-18
HUP0103778A2 (hu)	2002-05-29
AU2005201660A1 (en)	2005-05-12
MY122496A (en)	2006-04-29
KR20010075571A (ko)	2001-08-09
PT1413575E (pt)	2006-12-29
US20020032336A1 (en)	2002-03-14
HK1040081B (zh)	2005-05-13
CA2346142A1 (en)	2001-02-08
DE60015496T2 (de)	2005-10-27
JP4886951B2 (ja)	2012-02-29
AU6752600A (en)	2001-02-19
HK1040081A1 (en)	2002-05-24
JP2012051929A (ja)	2012-03-15
US20060004208A1 (en)	2006-01-05
CN1337951A (zh)	2002-02-27
EP1413575A9 (de)	2005-06-29
KR100646883B1 (ko)	2006-11-17
TWI234562B (en)	2005-06-21
CA2636755A1 (en)	2001-02-08
CA2346142C (en)	2008-10-14
IL142341A0 (en)	2002-03-10
BR0006978A (pt)	2001-06-19
CZ299710B6 (cs)	2008-10-29
ES2274171T3 (es)	2007-05-16
ATE342254T1 (de)	2006-11-15
US6613914B2 (en)	2003-09-02
US6953860B2 (en)	2005-10-11
PL347025A1 (en)	2002-03-11
US7247745B2 (en)	2007-07-24
ATE281437T1 (de)	2004-11-15
DE60031315T2 (de)	2007-04-26
PL201799B1 (pl)	2009-05-29
NO20011652D0 (no)	2001-04-02
NO318467B1 (no)	2005-03-21
EP1144382B1 (de)	2004-11-03
HU228678B1 (en)	2013-05-28
WO2001009102A3 (en)	2001-08-16

Publication	Publication Date	Title
DE69801489D1 (de)	2001-10-04	Verfahren zur herstellung von 1,1,1,3,3-pentafluorpropan
DE69915878D1 (de)	2004-04-29	Verfahren zur herstellung von 2,3-dihalogenpropanolen
DE69711669D1 (de)	2002-05-08	VERFAHREN ZUR HERSTELLUNG VON d,1-ALPHA-TOCOPHEROL
DE60003264D1 (de)	2003-07-17	Verfahren zur herstellung von glycerylethern
DE59906265D1 (de)	2003-08-14	Verfahren zur herstellung von 1,4-butandiol
DE59901552D1 (de)	2002-07-04	Verfahren zur herstellung von polyalkylenarylaten
DE50006772D1 (de)	2004-07-15	Verfahren zur herstellung von oxindolen
DE59905197D1 (de)	2003-05-28	Verfahren zur herstellung von hexandiol-1,6
DE50001895D1 (de)	2003-05-28	Verfahren zur herstellung von phosphonomethylglycin
ATE241588T1 (de)	2003-06-15	Verfahren zur herstellung von 3,5-difluoroanilin
ATE296850T1 (de)	2005-06-15	Verfahren zur herstellung von polyamiden
ATE366251T1 (de)	2007-07-15	Verfahren zur herstellung von 1,3- disubstituierten-4-oxocyclischen harnstoffen
DE60015496D1 (de)	2004-12-09	Verfahren zur herstellung von 3-substituierte 1,5-diarylpyrozole
ATE267839T1 (de)	2004-06-15	Verfahren zur herstellung von cyclo-(asp-dphe- nmeval-arg-gly)
ATE233238T1 (de)	2003-03-15	Verfahren zur herstellung von 3-acyl-indolen
DE69928784D1 (de)	2006-01-12	Verfahren zur herstellung von oxazolidin-2-on-derivaten
ATE275563T1 (de)	2004-09-15	Verfahren zur herstellung von 1,3- disubstituierten-4-oxocyclischen harnstoffen
ATE234337T1 (de)	2003-03-15	Verfahren zur herstellung von polyamiden
ATE295349T1 (de)	2005-05-15	Verfahren zur herstellung von ketiminen
ATE264829T1 (de)	2004-05-15	Verfahren zur herstellung von acylierten 1,3- dicarbonylverbindungen
DE69918337D1 (de)	2004-07-29	Verfahren zur herstellung von 2,6-dialkylnaphthalen
DE60011427D1 (de)	2004-07-15	Verfahren zur herstellung von 2-pyridylpiperidin-derivaten
DE59906901D1 (de)	2003-10-09	Verfahren zur herstellung von 1-substituierten 5-hydroxypyrazolen
DE59903764D1 (de)	2003-01-23	Verfahren zur herstellung von phytosqualan
DE50004440D1 (de)	2003-12-18	Verfahren zur herstellung von phosphonomethylglycin

Legal Events

Date	Code	Title	Description
2005-12-01	8364	No opposition during term of opposition
2006-06-29	8328	Change in the person/name/address of the agent	Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN