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DE3570038D1 - Steroids for use as immunomodulators - Google Patents

Steroids for use as immunomodulators

Info

Publication number
DE3570038D1
DE3570038D1 DE8585200423T DE3570038T DE3570038D1 DE 3570038 D1 DE3570038 D1 DE 3570038D1 DE 8585200423 T DE8585200423 T DE 8585200423T DE 3570038 T DE3570038 T DE 3570038T DE 3570038 D1 DE3570038 D1 DE 3570038D1
Authority
DE
Germany
Prior art keywords
sup
substituent
immunomodulators
steroids
oxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585200423T
Other languages
English (en)
Inventor
Jan Kelder
Hermanus Antonius Mari Verheul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of DE3570038D1 publication Critical patent/DE3570038D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8585200423T 1984-03-21 1985-03-20 Steroids for use as immunomodulators Expired DE3570038D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8400888 1984-03-21

Publications (1)

Publication Number Publication Date
DE3570038D1 true DE3570038D1 (en) 1989-06-15

Family

ID=19843679

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585200423T Expired DE3570038D1 (en) 1984-03-21 1985-03-20 Steroids for use as immunomodulators

Country Status (6)

Country Link
US (1) US4701450A (de)
EP (1) EP0159739B1 (de)
JP (1) JPS60209599A (de)
AT (1) ATE42895T1 (de)
DE (1) DE3570038D1 (de)
MX (1) MX9203811A (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3687692T2 (de) * 1985-11-13 1993-05-19 Japan Res Dev Corp Geschlechtshormone zur behandlung von immun-mangel-krankheiten.
JPH0621072B2 (ja) * 1986-11-12 1994-03-23 呉羽化学工業株式会社 エストラジオ−ル誘導体よりなる免疫調節剤
US4902681A (en) * 1987-08-27 1990-02-20 University Of Pennsylvania Inhibition of immune clearance using progesterone analogues
US4908358A (en) * 1987-08-27 1990-03-13 Trustees Of The University Of Pennsylvania Inhibition of immune clearance using progesterone analogues
IE63051B1 (en) * 1989-03-18 1995-03-22 Akzo Nv Pharmaceutical composition which contains a pharmaceutically suitable carrier and the compound having the structure (7alpha, 17alpha)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn- 3-one
US5342834A (en) * 1989-04-07 1994-08-30 The Population Council, Inc. Method for androgen supplementation
US5201280A (en) * 1989-06-06 1993-04-13 Reproductive Sciences, Inc. Method for preferential production of female turtles, lizards, and crocodiles
JP2683783B2 (ja) * 1992-07-10 1997-12-03 雪印乳業株式会社 シェーグレン症候群治療剤
US5639743A (en) * 1992-11-13 1997-06-17 University Of Georgia Research Foundation Compositions and methods for treating exocrine gland atrophy
DE69418744T2 (de) * 1993-03-05 1999-11-11 Akzo Nobel N.V., Arnheim/Arnhem Verwendung von Pregnanderivaten zur Behandlung von Tumoren
WO1994022451A1 (en) * 1993-04-07 1994-10-13 Oklahoma Medical Research Foundation Selective regulation of b lymphocyte precursors by hormones
IL123984A (en) * 1997-04-22 2004-09-27 Akzo Nobel Nv Pharmacological dosage units containing tibolone and carrier pharmacy are acceptable
AU4093799A (en) 1998-05-22 1999-12-13 Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
DE69907495T2 (de) * 1998-10-16 2004-05-06 Akzo Nobel N.V. (7alpha,17alpha)-17-hydroxy-7-methyl-19-nor-17-pregn-5-(10)-en-20-yn-3-on als reine verbindung
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
TWI265167B (en) * 1999-11-29 2006-11-01 Akzo Nobel Nv 3-methylene steroid derivatives
DE60129550T2 (de) * 2000-05-12 2008-04-10 The Government Of The United States Of America, As Represented By The Department Verwendung von niedrigen dosen estrogen in kombination mit immunotherapeutischen verbindungen zur behandlung von immunkrankheiten
US7462486B2 (en) 2000-05-12 2008-12-09 Oregon Health & Science University Methods of selecting T cell receptor V peptides for therapeutic use
US20040229854A1 (en) * 2000-11-28 2004-11-18 Pieter Haan De Immediate release dosage form for HRT
GB0125061D0 (en) * 2001-10-18 2001-12-12 Norton Healthcare Ltd Pharmaceutical composition
ES2284946T3 (es) * 2001-10-18 2007-11-16 Norton Healthcare Limited Formulaciones de tibolona.
CN1324041C (zh) * 2003-04-01 2007-07-04 上海迪赛诺医药科技开发有限公司 替勃龙晶型i的制备方法
KR20060028822A (ko) * 2003-05-23 2006-04-03 엔.브이. 오가논 다형성 티볼론을 포함하는 즉시-방출형 약학 제형
WO2005120517A1 (en) * 2004-06-07 2005-12-22 Strides Arcolab Limited Stable liquid suspension formulation comprising synthetic steroids and process for producing the same
US8053197B2 (en) 2004-07-30 2011-11-08 Oregon Health & Science University Methods for detecting and treating autoimmune disorders
US8175031B2 (en) 2004-11-18 2012-05-08 Telefonaktiebolaget Lm Ericsson (Publ) Method and apparatus for supporting packet data services in service area boundary regions
EP2671508B1 (de) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-Informatiksystem
EP1945240B1 (de) 2005-09-16 2016-12-28 Raptor Pharmaceutical Inc Zusammensetzungen mit rezeptor-assoziierten protein (rap) varianten, die für cr-haltige proteine spezifisch sind und ihre verwendungen
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
CA2760945A1 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
BR112018072371B1 (pt) * 2016-05-04 2024-04-30 Novalon S.A. Uso de um açúcar-álcool, composição farmacêutica, método para preparar uma forma de dosagem sólida compreendendo tibolona e uso de uma composição farmacêutica

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB885782A (en) * 1958-01-24 1961-12-28 Searle & Co Improvements in or relating to androstenone and androstanone derivatives
GB884412A (en) * 1958-09-20 1961-12-13 Organon Labor Ltd New 6-methyl-19-nor-steroids and process for the preparation thereof
US3012045A (en) * 1959-01-22 1961-12-05 Searle & Co 17alpha-alkenyl derivatives of 6alpha-methyl-17beta-hydroxy-19-nor-4-androsten-3-one
BE593958A (nl) * 1959-08-17 1960-12-01 Organon Nv Werkwijze ter bereidung van op plaats 3 niet geoxygeneerde 19-nor-steroiden
GB941634A (en) * 1960-11-16 1963-11-13 Upjohn Co Improvements in or relating to steroids and the manufacture thereof
BE640298A (de) * 1962-11-23
BE665514A (de) * 1964-06-16
BE665515A (de) * 1964-06-17
US3515719A (en) * 1967-03-15 1970-06-02 Upjohn Co 7-methyl-6,19-epoxy steroids of the androstane series
NL6901532A (de) * 1969-01-30 1970-08-03
US4412993A (en) * 1980-01-25 1983-11-01 The Upjohn Company Method of treating pseudopregnancy, galactorrhea and mastitis in mammals
US4546098A (en) * 1984-04-13 1985-10-08 The Rockefeller University Estrogen synthesis inhibitors

Also Published As

Publication number Publication date
ATE42895T1 (de) 1989-05-15
EP0159739B1 (de) 1989-05-10
US4701450A (en) 1987-10-20
MX9203811A (es) 1992-07-01
EP0159739A1 (de) 1985-10-30
JPS60209599A (ja) 1985-10-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AKZO NOBEL N.V., ARNHEIM/ARNHEM, NL

8339 Ceased/non-payment of the annual fee