DE3486495D1 - Hundecoronavirus - Google Patents
HundecoronavirusInfo
- Publication number
- DE3486495D1 DE3486495D1 DE3486495T DE3486495T DE3486495D1 DE 3486495 D1 DE3486495 D1 DE 3486495D1 DE 3486495 T DE3486495 T DE 3486495T DE 3486495 T DE3486495 T DE 3486495T DE 3486495 D1 DE3486495 D1 DE 3486495D1
- Authority
- DE
- Germany
- Prior art keywords
- canine coronavirus
- coronavirus
- canine
- attenuated
- intestines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14311—Parvovirus, e.g. minute virus of mice
- C12N2750/14334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
- C12N2760/18634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/818—Viral vaccine for canidae or mustelidae, e.g. dogs, foxes, minks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/504,434 US4567043A (en) | 1983-06-15 | 1983-06-15 | Canine corona virus vaccine |
US06/618,638 US4567042A (en) | 1983-06-15 | 1984-06-07 | Inactivated canine coronavirus vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3486495D1 true DE3486495D1 (de) | 2004-11-25 |
Family
ID=27054825
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3486293T Expired - Lifetime DE3486293T3 (de) | 1983-06-15 | 1984-06-14 | Impfstoff-Zubereitung. |
DE3486292T Expired - Lifetime DE3486292T2 (de) | 1983-06-15 | 1984-06-14 | Tierärztliche Impfstoffe. |
DE8484902632T Expired - Lifetime DE3481582D1 (de) | 1983-06-15 | 1984-06-14 | Impfstoff gegen hundecoronavirus. |
DE3486495T Expired - Lifetime DE3486495D1 (de) | 1983-06-15 | 1984-06-14 | Hundecoronavirus |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3486293T Expired - Lifetime DE3486293T3 (de) | 1983-06-15 | 1984-06-14 | Impfstoff-Zubereitung. |
DE3486292T Expired - Lifetime DE3486292T2 (de) | 1983-06-15 | 1984-06-14 | Tierärztliche Impfstoffe. |
DE8484902632T Expired - Lifetime DE3481582D1 (de) | 1983-06-15 | 1984-06-14 | Impfstoff gegen hundecoronavirus. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4567042A (de) |
EP (4) | EP0345911B1 (de) |
AT (4) | ATE280217T1 (de) |
DE (4) | DE3486293T3 (de) |
ES (1) | ES8604422A1 (de) |
NL (1) | NL940017I2 (de) |
WO (1) | WO1985000014A1 (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4990367A (en) * | 1987-03-09 | 1991-02-05 | Diamond Scientific Company | Canine distemper virus vaccine |
ES2052685T3 (es) * | 1987-03-17 | 1994-07-16 | Akzo Nv | Metodo para producir un adyuvante libre. |
US5565209A (en) * | 1987-03-17 | 1996-10-15 | Akzo Nobel N.V. | Adjuvant mixture |
US4904468A (en) * | 1987-06-08 | 1990-02-27 | Norden Laboratories, Inc. | Canine coronavirus vaccine |
US5911999A (en) * | 1987-09-28 | 1999-06-15 | Pfizer, Inc. | Vaccine based on TGEV for protection of dogs against canine coronavirus |
US5232694A (en) * | 1989-05-03 | 1993-08-03 | Akzo N.V. | Canine corona virus vaccine |
US5672350A (en) * | 1989-08-22 | 1997-09-30 | Veterinary Infectious Disease Organization | Recombinant bovine coronavirus E2 and E3 polypeptides and vaccines |
US6004563A (en) * | 1990-11-07 | 1999-12-21 | American Home Products Corporation | Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same |
US6372224B1 (en) | 1990-11-14 | 2002-04-16 | Pfizer Inc. | Canine coronavirus S gene and uses therefor |
US6057436A (en) * | 1990-11-14 | 2000-05-02 | Pfizer Inc. | Canine coronavirus S gene and uses therefor |
DE69233270T2 (de) * | 1991-04-25 | 2004-09-30 | Akzo Nobel N.V. | Subeinheits-Impfstoff gegen Hundecoronavirus |
US5750112A (en) * | 1993-02-26 | 1998-05-12 | Solvay Animal Health, Inc. | Canine coronavirus vaccine from feline enteric coronavirus |
US20040048235A1 (en) * | 1995-08-29 | 2004-03-11 | V.I. Technologies, Inc. | Methods and compositions for the selective modification of nucleic acids |
US20040053208A1 (en) * | 1995-08-29 | 2004-03-18 | V. I. TECHNOLOGIES, Inc. | Methods to selectively inactivate parasites in biological compositions |
GB9622159D0 (en) * | 1996-10-24 | 1996-12-18 | Solvay Sociutu Anonyme | Polyanionic polymers as adjuvants for mucosal immunization |
US6093564A (en) | 1997-10-03 | 2000-07-25 | V.I. Technologies, Inc. | Methods and compositions for the selective modification of nucleic acids |
US6369048B1 (en) | 1998-01-12 | 2002-04-09 | V.I. Technologies, Inc. | Methods and compositions for inactivating viruses |
FR2775601B1 (fr) | 1998-03-03 | 2001-09-21 | Merial Sas | Vaccins vivants recombines et adjuves |
US6617100B2 (en) | 1998-09-25 | 2003-09-09 | V.I. Technologies, Inc. | Solid phase quenching systems |
US6150109A (en) | 1999-01-25 | 2000-11-21 | V. I. TECHNOLOGIES, Inc. | Lipophilic quenching of viral inactivating agents |
US20020131958A1 (en) * | 2001-01-22 | 2002-09-19 | John Chapman | Method for purifying a biological composition |
US20030129161A1 (en) * | 2001-09-17 | 2003-07-10 | Hsien-Jue Chu | Interleukin-12 as a veterinary vaccine adjuvant |
US7790178B2 (en) | 2002-12-19 | 2010-09-07 | Intervet International B.V. | Trivalent vaccine with maternal anitbody transfer via the milk |
US20050089533A1 (en) * | 2003-01-29 | 2005-04-28 | Joseph Frantz | Canine vaccines against Bordetella bronchiseptica |
CN1835767A (zh) * | 2003-01-29 | 2006-09-20 | 辉瑞产品公司 | 对抗支气管败血性博德特氏杆菌的犬疫苗 |
US9023366B2 (en) | 2003-07-01 | 2015-05-05 | The Royal Veterinary College | Vaccine composition for vaccinating dogs against canine infectious respiratory disease (CIRD) |
GB0315323D0 (en) * | 2003-07-01 | 2003-08-06 | Royal Veterinary College | Vaccine composition |
JP2007508837A (ja) * | 2003-10-23 | 2007-04-12 | ファイザー・プロダクツ・インク | 歯周疾患のためのワクチン |
EP1871410A2 (de) * | 2005-04-07 | 2008-01-02 | Pharmacia & Upjohn Company LLC | Formulierungen und verfahren zur herstellung von bordetella bronchiseptica p68 antigen und impfstoffen |
PT1780216E (pt) * | 2005-10-26 | 2011-02-03 | Canio Buonavoglia | Coronavírus canino pantrópico |
US7682619B2 (en) * | 2006-04-06 | 2010-03-23 | Cornell Research Foundation, Inc. | Canine influenza virus |
KR101013226B1 (ko) * | 2008-05-14 | 2011-02-10 | 녹십자수의약품(주) | 개 바이러스성 설사병 예방용 백신 |
US20110110980A1 (en) * | 2009-09-02 | 2011-05-12 | Wyeth Llc | Heterlogous prime-boost immunization regimen |
UY34745A (es) | 2012-04-18 | 2013-11-29 | Zoetis Llc | Vacunas y procedimientos para tratar la enfermedad de lyme en perros |
US20140170180A1 (en) | 2012-12-17 | 2014-06-19 | Boehringer Ingelheim Vetmedica, Inc. | Porcine parvovirus 5a, methods of use and vaccine |
US20140234354A1 (en) | 2013-02-15 | 2014-08-21 | Boehringer Ingelheim Vetmedica, Inc. | Porcine parvovirus 5b, methods of use and vaccine |
US9579373B2 (en) | 2013-03-15 | 2017-02-28 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
WO2019092027A1 (en) | 2017-11-09 | 2019-05-16 | Boehringer Ingelheim Vetmedica Gmbh | Sapelovirus immunogenic compositions and uses thereof |
WO2020142778A1 (en) | 2019-01-04 | 2020-07-09 | Boehringer Ingelheim Animal Health USA Inc. | Attenuated bordetella bronchiseptica strains, oral vaccines containing the attenuated strains, and methods of making & use thereof |
CN109765384B (zh) * | 2019-01-29 | 2022-11-18 | 北京勤邦生物技术有限公司 | 一种犬冠状病毒抗体荧光检测试纸条及其制备方法和应用 |
CN112402599B (zh) * | 2019-08-23 | 2023-06-27 | 中国农业科学院特产研究所 | 一种犬用犬瘟热、细小病毒病二联灭活疫苗及其制备方法 |
JPWO2022149342A1 (de) * | 2021-01-06 | 2022-07-14 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3143474A (en) * | 1962-07-30 | 1964-08-04 | Sterling Drug Inc | Preparation of duck-embryo modified infectious canine hepatitis virus vaccine |
US3704203A (en) † | 1967-08-24 | 1972-11-28 | Diamond Lab Inc | Transmissible gastroenteritis vaccines and methods of producing the same |
US3652761A (en) * | 1969-09-04 | 1972-03-28 | Corning Glass Works | Immunochemical composites and antigen or antibody purification therewith |
US3959251A (en) * | 1970-06-25 | 1976-05-25 | Exploaterings Aktiebolaget T.B.F. | Stabilized agar product and method for its stabilization |
-
1984
- 1984-06-07 US US06/618,638 patent/US4567042A/en not_active Expired - Lifetime
- 1984-06-14 DE DE3486293T patent/DE3486293T3/de not_active Expired - Lifetime
- 1984-06-14 AT AT89201996T patent/ATE280217T1/de not_active IP Right Cessation
- 1984-06-14 DE DE3486292T patent/DE3486292T2/de not_active Expired - Lifetime
- 1984-06-14 DE DE8484902632T patent/DE3481582D1/de not_active Expired - Lifetime
- 1984-06-14 EP EP19890201996 patent/EP0345911B1/de not_active Expired - Lifetime
- 1984-06-14 AT AT84902632T patent/ATE50913T1/de not_active IP Right Cessation
- 1984-06-14 EP EP84902632A patent/EP0145783B2/de not_active Expired - Lifetime
- 1984-06-14 DE DE3486495T patent/DE3486495D1/de not_active Expired - Lifetime
- 1984-06-14 EP EP89202001A patent/EP0344872B2/de not_active Expired - Lifetime
- 1984-06-14 WO PCT/US1984/000904 patent/WO1985000014A1/en active IP Right Grant
- 1984-06-14 EP EP19890201017 patent/EP0329264B1/de not_active Expired - Lifetime
- 1984-12-14 ES ES538588A patent/ES8604422A1/es not_active Expired
-
1989
- 1989-04-20 AT AT89201017T patent/ATE103181T1/de not_active IP Right Cessation
- 1989-07-31 AT AT89202001T patent/ATE103180T1/de not_active IP Right Cessation
-
1994
- 1994-08-18 NL NL940017C patent/NL940017I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
EP0145783A1 (de) | 1985-06-26 |
DE3481582D1 (de) | 1990-04-19 |
EP0329264B1 (de) | 1994-03-23 |
EP0145783B1 (de) | 1990-03-14 |
ATE103180T1 (de) | 1994-04-15 |
EP0345911B1 (de) | 2004-10-20 |
NL940017I2 (nl) | 2001-02-01 |
DE3486293T2 (de) | 1994-06-30 |
NL940017I1 (nl) | 1994-10-17 |
DE3486292T2 (de) | 1994-06-30 |
ATE103181T1 (de) | 1994-04-15 |
DE3486293T3 (de) | 2002-11-21 |
EP0344872B1 (de) | 1994-03-23 |
WO1985000014A1 (en) | 1985-01-03 |
ATE50913T1 (de) | 1990-03-15 |
DE3486293D1 (de) | 1994-04-28 |
EP0329264A2 (de) | 1989-08-23 |
EP0145783A4 (de) | 1985-10-14 |
EP0329264A3 (en) | 1989-12-13 |
EP0345911A1 (de) | 1989-12-13 |
US4567042A (en) | 1986-01-28 |
ATE280217T1 (de) | 2004-11-15 |
EP0145783B2 (de) | 2004-01-02 |
ES8604422A1 (es) | 1986-02-01 |
DE3486293T4 (de) | 1995-06-14 |
DE3486292D1 (de) | 1994-04-28 |
ES538588A0 (es) | 1986-02-01 |
EP0344872A1 (de) | 1989-12-06 |
EP0344872B2 (de) | 2002-04-24 |
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