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DE3260164D1 - Novel platinum complexes - Google Patents

Novel platinum complexes

Info

Publication number
DE3260164D1
DE3260164D1 DE8282200020T DE3260164T DE3260164D1 DE 3260164 D1 DE3260164 D1 DE 3260164D1 DE 8282200020 T DE8282200020 T DE 8282200020T DE 3260164 T DE3260164 T DE 3260164T DE 3260164 D1 DE3260164 D1 DE 3260164D1
Authority
DE
Germany
Prior art keywords
platinum complexes
novel platinum
novel
complexes
platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282200020T
Other languages
English (en)
Inventor
Totani Tetsushi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of DE3260164D1 publication Critical patent/DE3260164D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8282200020T 1981-01-23 1982-01-07 Novel platinum complexes Expired DE3260164D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56009463A JPS57123198A (en) 1981-01-23 1981-01-23 Novel platinum complex

Publications (1)

Publication Number Publication Date
DE3260164D1 true DE3260164D1 (en) 1984-06-28

Family

ID=11720966

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282200020T Expired DE3260164D1 (en) 1981-01-23 1982-01-07 Novel platinum complexes

Country Status (7)

Country Link
US (1) US4575550A (de)
EP (1) EP0057023B1 (de)
JP (1) JPS57123198A (de)
AU (1) AU557336B2 (de)
CA (1) CA1180009A (de)
DE (1) DE3260164D1 (de)
GB (1) GB2091731B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5921697A (ja) * 1982-06-24 1984-02-03 Yoshinori Kitani 新規な白金錯体
JPS59222498A (ja) * 1983-06-01 1984-12-14 Shionogi & Co Ltd 新規グリコ−ル酸系白金錯体および抗悪性腫瘍剤
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
JPS617283A (ja) * 1984-06-20 1986-01-13 Shionogi & Co Ltd 新規白金錯体および抗悪性腫瘍剤
IL76889A0 (en) * 1984-11-02 1986-02-28 Johnson Matthey Plc Solubilised platinum compound,method for the production thereof and pharmaceutical compositions containing the same
NZ214504A (en) * 1984-12-17 1988-07-28 American Cyanamid Co Platinum/saccharide complexes and pharmaceutical compositions
JPS6296A (ja) * 1985-03-06 1987-01-06 Sumitomo Pharmaceut Co Ltd 脂溶性白金（２）錯体
JPH0665648B2 (ja) * 1985-09-25 1994-08-24 塩野義製薬株式会社 白金系抗癌物質の安定な凍結真空乾燥製剤
EP0270682A4 (de) * 1986-05-21 1989-04-12 Kuraray Co Neue komplexe deren herstellung und verwendung als arzneimittel.
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
CA1327039C (en) * 1986-12-18 1994-02-15 Tetsushi Totani Ammine-alicyclic amine-platinum complexes and antitumor agents
ATE87314T1 (de) * 1987-07-17 1993-04-15 Univ Georgetown Platin-arzneimittel.
US4895936A (en) * 1987-07-17 1990-01-23 Georgetown University Platinum pharmaceuticals
US4956459A (en) * 1987-07-17 1990-09-11 Georgetown University Platinum compounds suitable for use as pharmaceuticals
US4895935A (en) * 1987-07-17 1990-01-23 Georgetown University Platinum pharmaceuticals
JPH01294683A (ja) * 1988-02-04 1989-11-28 Kanebo Ltd 新規白金錯体および該化合物を有効成分とする抗腫瘍剤並びに該化合物製造用中間体
WO1990003402A1 (en) * 1988-09-27 1990-04-05 Kuraray Co., Ltd. Novel composite, process for its preparation and medicinal use thereof
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US4946954A (en) * 1989-01-17 1990-08-07 Georgetown University Platinum pharmaceutical agents
US5130450A (en) * 1990-04-25 1992-07-14 Nippon Kayaku Kabushiki Kaisha Platinum complexes
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US20100034874A1 (en) * 2006-12-08 2010-02-11 Katayama Chemical Industries Co., Ltd. Liposome encapsulating ammine-platinum complex at high concentration, and method for production of the liposome
CN100500682C (zh) * 2007-02-14 2009-06-17 江苏奥赛康药业有限公司 一种奈达铂的提纯方法
CN101402655B (zh) * 2008-11-07 2011-06-15 江苏奥赛康药业有限公司 一种米铂的制备方法
CN102417522B (zh) * 2011-10-20 2014-11-26 南京工业大学 一种奈达铂的制备方法
CN105399777A (zh) * 2015-11-23 2016-03-16 南京先声东元制药有限公司 一种奈达铂类似物及其制备方法
CN105622673B (zh) * 2016-01-25 2018-11-06 南开大学 具有抗癌活性的糖基化四价铂类化合物、制备方法及应用
CN112225757B (zh) * 2020-09-17 2023-07-21 昆明贵研药业有限公司 一种洛铂三水合物的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605550A5 (de) * 1972-06-08 1978-09-29 Research Corp
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
US4225529A (en) * 1977-10-19 1980-09-30 Johnson, Matthey & Co., Limited Compositions containing platinum
DE2845371A1 (de) * 1977-10-19 1979-04-26 Johnson Matthey Co Ltd Platinkomplexverbindung, pharmazeutische stoffzusammensetzung mit einer solchen verbindung und deren anwendung
US4234500A (en) * 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
US4291023A (en) * 1979-03-07 1981-09-22 Engelhard Minerals & Chemicals Corp. Method for treating tumors using cis-diammineplatinum (II) organophosphate complexes
US4248840A (en) * 1979-03-07 1981-02-03 Engelhard Minerals And Chemicals Corporation Cis-diammineplatinum(II) orthophosphate complexes
US4234499A (en) * 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Cis-diammireplatinum(II) organophosphate complexes
US4271085A (en) * 1979-06-20 1981-06-02 Engelhard Minerals & Chemicals Corporation Cis-platinum (II) amine lactate complexes
US4322362A (en) * 1980-07-28 1982-03-30 Bristol-Myers Company Salts of 2-hydroxymalonate platinum complexes

Also Published As

Publication number Publication date
JPS637194B2 (de) 1988-02-15
JPS57123198A (en) 1982-07-31
CA1180009A (en) 1984-12-27
GB2091731A (en) 1982-08-04
EP0057023A1 (de) 1982-08-04
AU7976582A (en) 1982-07-29
GB2091731B (en) 1985-01-30
EP0057023B1 (de) 1984-05-23
AU557336B2 (en) 1986-12-18
US4575550A (en) 1986-03-11

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