CY1122472T1 - Συζευγμα-αντισωματος-φαρμακου και η χρηση αυτου για την αγωγη του καρκινου - Google Patents
Συζευγμα-αντισωματος-φαρμακου και η χρηση αυτου για την αγωγη του καρκινουInfo
- Publication number
- CY1122472T1 CY1122472T1 CY20191101344T CY191101344T CY1122472T1 CY 1122472 T1 CY1122472 T1 CY 1122472T1 CY 20191101344 T CY20191101344 T CY 20191101344T CY 191101344 T CY191101344 T CY 191101344T CY 1122472 T1 CY1122472 T1 CY 1122472T1
- Authority
- CY
- Cyprus
- Prior art keywords
- antibody
- drug conjugate
- treatment
- cancer
- relates
- Prior art date
Links
- 239000000611 antibody drug conjugate Substances 0.000 title abstract 4
- 229940049595 antibody-drug conjugate Drugs 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title abstract 2
- OFDNQWIFNXBECV-VFSYNPLYSA-N dolastatin 10 Chemical class CC(C)[C@H](N(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C=1SC=CN=1)CC1=CC=CC=C1 OFDNQWIFNXBECV-VFSYNPLYSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- Health & Medical Sciences (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Abstract
Η παρούσα εφεύρεση σχετίζεται με ένα σύζευγμα αντισώματος-φαρμάκου. Από μια άποψη του θέματος, η εφεύρεση σχετίζεται με ένα σύζευγμα αντισώματος- φαρμάκου περιλαμβάνοντας ένα αντίσωμα δυνάμενο δέσμευσης σε ένα Στόχο, με το εν λόγω αντίσωμα να συζεύγεται σε τουλάχιστον ένα φάρμακο που επιλέγεται από παράγωγα δολαστατίνης 10 και αουριστατινών. Η εφεύρεση περιλαμβάνει επίσης μέθοδο αγωγής και τη χρήση του εν λόγω συζεύγματος αντισώματος-φαρμάκου για την αγωγή του καρκίνου.
Applications Claiming Priority (2)
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EP14305621 | 2014-04-25 | ||
PCT/EP2015/059052 WO2015162293A1 (en) | 2014-04-25 | 2015-04-27 | Antibody-drug-conjugate and its use for the treatment of cancer |
Publications (1)
Publication Number | Publication Date |
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CY1122472T1 true CY1122472T1 (el) | 2021-01-27 |
Family
ID=50630737
Family Applications (1)
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CY20191101344T CY1122472T1 (el) | 2014-04-25 | 2019-12-20 | Συζευγμα-αντισωματος-φαρμακου και η χρηση αυτου για την αγωγη του καρκινου |
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US (5) | US10314921B2 (el) |
EP (2) | EP3607996B1 (el) |
JP (1) | JP6567551B2 (el) |
KR (1) | KR102459647B1 (el) |
CN (1) | CN106470708B (el) |
AU (1) | AU2015250761B2 (el) |
BR (1) | BR112016024363A2 (el) |
CA (1) | CA2946796C (el) |
CY (1) | CY1122472T1 (el) |
DK (1) | DK3134125T3 (el) |
ES (1) | ES2764110T3 (el) |
HR (1) | HRP20192254T1 (el) |
HU (1) | HUE047952T2 (el) |
LT (1) | LT3134125T (el) |
MX (1) | MX2016013999A (el) |
PL (1) | PL3134125T3 (el) |
PT (1) | PT3134125T (el) |
RS (1) | RS59799B1 (el) |
RU (1) | RU2685259C2 (el) |
SI (1) | SI3134125T1 (el) |
WO (1) | WO2015162293A1 (el) |
ZA (1) | ZA201607415B (el) |
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2015
- 2015-04-27 RS RS20191700A patent/RS59799B1/sr unknown
- 2015-04-27 LT LTEP15720314.2T patent/LT3134125T/lt unknown
- 2015-04-27 JP JP2016564173A patent/JP6567551B2/ja active Active
- 2015-04-27 EP EP19195042.7A patent/EP3607996B1/en active Active
- 2015-04-27 BR BR112016024363A patent/BR112016024363A2/pt not_active Application Discontinuation
- 2015-04-27 HU HUE15720314A patent/HUE047952T2/hu unknown
- 2015-04-27 ES ES15720314T patent/ES2764110T3/es active Active
- 2015-04-27 CN CN201580034144.1A patent/CN106470708B/zh active Active
- 2015-04-27 CA CA2946796A patent/CA2946796C/en active Active
- 2015-04-27 RU RU2016145445A patent/RU2685259C2/ru active
- 2015-04-27 SI SI201531056T patent/SI3134125T1/sl unknown
- 2015-04-27 AU AU2015250761A patent/AU2015250761B2/en not_active Ceased
- 2015-04-27 DK DK15720314.2T patent/DK3134125T3/da active
- 2015-04-27 PT PT157203142T patent/PT3134125T/pt unknown
- 2015-04-27 US US15/306,404 patent/US10314921B2/en active Active
- 2015-04-27 KR KR1020167031822A patent/KR102459647B1/ko active IP Right Grant
- 2015-04-27 MX MX2016013999A patent/MX2016013999A/es unknown
- 2015-04-27 WO PCT/EP2015/059052 patent/WO2015162293A1/en active Application Filing
- 2015-04-27 EP EP15720314.2A patent/EP3134125B1/en active Active
- 2015-04-27 PL PL15720314T patent/PL3134125T3/pl unknown
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2016
- 2016-10-27 ZA ZA2016/07415A patent/ZA201607415B/en unknown
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2018
- 2018-01-31 US US15/885,220 patent/US10912841B2/en active Active
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2019
- 2019-04-16 US US16/385,597 patent/US11219693B2/en active Active
- 2019-12-16 HR HRP20192254TT patent/HRP20192254T1/hr unknown
- 2019-12-20 CY CY20191101344T patent/CY1122472T1/el unknown
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2020
- 2020-10-28 US US17/083,010 patent/US11517625B2/en active Active
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2021
- 2021-11-15 US US17/454,931 patent/US11918656B2/en active Active
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