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CY1122472T1 - Συζευγμα-αντισωματος-φαρμακου και η χρηση αυτου για την αγωγη του καρκινου - Google Patents

Συζευγμα-αντισωματος-φαρμακου και η χρηση αυτου για την αγωγη του καρκινου

Info

Publication number
CY1122472T1
CY1122472T1 CY20191101344T CY191101344T CY1122472T1 CY 1122472 T1 CY1122472 T1 CY 1122472T1 CY 20191101344 T CY20191101344 T CY 20191101344T CY 191101344 T CY191101344 T CY 191101344T CY 1122472 T1 CY1122472 T1 CY 1122472T1
Authority
CY
Cyprus
Prior art keywords
antibody
drug conjugate
treatment
cancer
relates
Prior art date
Application number
CY20191101344T
Other languages
English (en)
Inventor
Ian RILATT
Michel Perez
Liliane Goetsch
Matthieu BROUSSAS
Charlotte Beau-Larvor
Jean-François HAEUW
Original Assignee
Pierre Fabre Médicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Médicament filed Critical Pierre Fabre Médicament
Publication of CY1122472T1 publication Critical patent/CY1122472T1/el

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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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Abstract

Η παρούσα εφεύρεση σχετίζεται με ένα σύζευγμα αντισώματος-φαρμάκου. Από μια άποψη του θέματος, η εφεύρεση σχετίζεται με ένα σύζευγμα αντισώματος- φαρμάκου περιλαμβάνοντας ένα αντίσωμα δυνάμενο δέσμευσης σε ένα Στόχο, με το εν λόγω αντίσωμα να συζεύγεται σε τουλάχιστον ένα φάρμακο που επιλέγεται από παράγωγα δολαστατίνης 10 και αουριστατινών. Η εφεύρεση περιλαμβάνει επίσης μέθοδο αγωγής και τη χρήση του εν λόγω συζεύγματος αντισώματος-φαρμάκου για την αγωγή του καρκίνου.
CY20191101344T 2014-04-25 2019-12-20 Συζευγμα-αντισωματος-φαρμακου και η χρηση αυτου για την αγωγη του καρκινου CY1122472T1 (el)

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US20210038738A1 (en) 2021-02-11
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