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CY1114626T1 - Μεθοδοι κυκλοπολυαιθυλενογλυκολιωσης και πρωτεϊνες/πεπτιδια που παραγονται με αυτες τις μεθοδους - Google Patents

Μεθοδοι κυκλοπολυαιθυλενογλυκολιωσης και πρωτεϊνες/πεπτιδια που παραγονται με αυτες τις μεθοδους

Info

Publication number
CY1114626T1
CY1114626T1 CY20111101170T CY111101170T CY1114626T1 CY 1114626 T1 CY1114626 T1 CY 1114626T1 CY 20111101170 T CY20111101170 T CY 20111101170T CY 111101170 T CY111101170 T CY 111101170T CY 1114626 T1 CY1114626 T1 CY 1114626T1
Authority
CY
Cyprus
Prior art keywords
methods
glycology
cyclothylene
proteins
peptides produced
Prior art date
Application number
CY20111101170T
Other languages
English (en)
Inventor
Frees Shawn De
David Zopf
Robert Bayer
Caryn Bowe
David Hakes
Xi Chen
Original Assignee
Biogenerix Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/410,997 external-priority patent/US7157277B2/en
Priority claimed from US10/410,897 external-priority patent/US7179617B2/en
Priority claimed from US10/411,049 external-priority patent/US7297511B2/en
Priority claimed from US10/411,043 external-priority patent/US7439043B2/en
Priority claimed from US10/411,012 external-priority patent/US7265084B2/en
Priority claimed from US10/410,945 external-priority patent/US7214660B2/en
Priority claimed from US10/410,913 external-priority patent/US7265085B2/en
Priority claimed from US10/410,980 external-priority patent/US7399613B2/en
Priority claimed from US10/411,037 external-priority patent/US7125843B2/en
Priority claimed from US10/411,044 external-priority patent/US8008252B2/en
Priority claimed from US10/410,930 external-priority patent/US7226903B2/en
Priority claimed from US10/410,962 external-priority patent/US7173003B2/en
Priority claimed from US10/411,026 external-priority patent/US7795210B2/en
Application filed by Biogenerix Ag filed Critical Biogenerix Ag
Publication of CY1114626T1 publication Critical patent/CY1114626T1/el

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
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Abstract

Η εφεύρεση περιλαμβάνει μεθόδους και συνθέσεις για επαναμοντελοποίηση μορίου πεπτιδίου που συμπεριλαμβάνει την προσθήκη η απαλοιφή μιας ή περισσοτέρων γλυκοζύλ ομάδων σε ένα πεπτίδιο ή/και την προσθήκη μιας τροποποιητικής ομάδας σε ένα πεπτίδιο.
CY20111101170T 2003-04-09 2011-11-28 Μεθοδοι κυκλοπολυαιθυλενογλυκολιωσης και πρωτεϊνες/πεπτιδια που παραγονται με αυτες τις μεθοδους CY1114626T1 (el)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US10/411,049 US7297511B2 (en) 2001-10-10 2003-04-09 Interferon alpha: remodeling and glycoconjugation of interferon alpha
US10/411,043 US7439043B2 (en) 2001-10-10 2003-04-09 Galactosyl nucleotide sugars
US10/411,012 US7265084B2 (en) 2001-10-10 2003-04-09 Glycopegylation methods and proteins/peptides produced by the methods
US10/410,945 US7214660B2 (en) 2001-10-10 2003-04-09 Erythropoietin: remodeling and glycoconjugation of erythropoietin
US10/410,997 US7157277B2 (en) 2001-11-28 2003-04-09 Factor VIII remodeling and glycoconjugation of Factor VIII
US10/410,980 US7399613B2 (en) 2001-10-10 2003-04-09 Sialic acid nucleotide sugars
US10/410,897 US7179617B2 (en) 2001-10-10 2003-04-09 Factor IX: remolding and glycoconjugation of Factor IX
US10/411,044 US8008252B2 (en) 2001-10-10 2003-04-09 Factor VII: remodeling and glycoconjugation of Factor VII
US10/410,930 US7226903B2 (en) 2001-10-10 2003-04-09 Interferon beta: remodeling and glycoconjugation of interferon beta
US10/410,962 US7173003B2 (en) 2001-10-10 2003-04-09 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US10/411,026 US7795210B2 (en) 2001-10-10 2003-04-09 Protein remodeling methods and proteins/peptides produced by the methods
US10/411,037 US7125843B2 (en) 2001-10-19 2003-04-09 Glycoconjugates including more than one peptide
US10/410,913 US7265085B2 (en) 2001-10-10 2003-04-09 Glycoconjugation methods and proteins/peptides produced by the methods
EP04750118A EP1615945B1 (en) 2003-04-09 2004-04-09 Glycopegylation methods and proteins/peptides produced by the methods

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PL (1) PL1615945T3 (el)
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