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CY1106542T1 - Μεθοδος για παρασκευη φαρμακευτικων συνθεσεων για χρηση με συνταγοποιησεις μαλακης ζελατινης - Google Patents

Μεθοδος για παρασκευη φαρμακευτικων συνθεσεων για χρηση με συνταγοποιησεις μαλακης ζελατινης

Info

Publication number
CY1106542T1
CY1106542T1 CY20071100560T CY071100560T CY1106542T1 CY 1106542 T1 CY1106542 T1 CY 1106542T1 CY 20071100560 T CY20071100560 T CY 20071100560T CY 071100560 T CY071100560 T CY 071100560T CY 1106542 T1 CY1106542 T1 CY 1106542T1
Authority
CY
Cyprus
Prior art keywords
active ingredient
concentration
pharmaceutically active
prescriptions
pharmaceutical compositions
Prior art date
Application number
CY20071100560T
Other languages
English (en)
Inventor
Stephen Charles Tindal
Christopher Clive Webster
Josesphine Christine Ferdinando
Jacqueline Carol Lewis
Original Assignee
R.P. Scherer Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24606884&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1106542(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by R.P. Scherer Technologies, Inc. filed Critical R.P. Scherer Technologies, Inc.
Publication of CY1106542T1 publication Critical patent/CY1106542T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η εφεύρεση που αποκαλύπτεται εδώ είναι μέθοδος για αύξηση της επιτεύξιμης συγκέντρωσης φαρμακευτικώς δραστικού συστατικού σχετικού για να πληρώσει το ιξώδες της σύνθεσης για μονάδες δοσολογίας. Η μέθοδος είναι ιδιαίτερα χρήσιμη στην παρασκευή καψουλών μαλακής ζελατίνης που περιέχει ιμπουπροφένη, ναπροξένη, ινδομεθακίνη και ακεταμινοφαίνη, ως φαρμακευτικώς δραστικό συστατικό. Σαν αποτέλεσμα της μεθόδου, μικρότερες ποσότητες συστατικών σύνθεσης άλλων εκτός του φαρμακευτικώς δραστικού συστατικού χρειάζονται για να επιτευχθεί η ίδια θεραπευτικώς αποτελεσματική δοσολογία, αυξάνοντας έτσι σημαντικά τη συγκέντρωση του φαρμακευτικώς δραστικού συστατικού, που έχει σαν αποτέλεσμα είτε μείωση στον συνολικό όγκο πλήρωσης και μέγεθος δοσολογίας μονάδος είτε αύξηση στη συγκέντρωση φαρμακευτικώς δραστικού συστατικού ανά μορφή δοσολογίας.
CY20071100560T 2000-08-29 2007-04-26 Μεθοδος για παρασκευη φαρμακευτικων συνθεσεων για χρηση με συνταγοποιησεις μαλακης ζελατινης CY1106542T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/649,947 US6387400B1 (en) 2000-08-29 2000-08-29 Process for preparing pharmaceutical compositions for use with soft gelatin formulations
PCT/US2001/026711 WO2002017855A2 (en) 2000-08-29 2001-08-28 Process for preparing pharmaceutical compositions for use with soft gelatin formulations

Publications (1)

Publication Number Publication Date
CY1106542T1 true CY1106542T1 (el) 2012-01-25

Family

ID=24606884

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100560T CY1106542T1 (el) 2000-08-29 2007-04-26 Μεθοδος για παρασκευη φαρμακευτικων συνθεσεων για χρηση με συνταγοποιησεις μαλακης ζελατινης

Country Status (24)

Country Link
US (1) US6387400B1 (el)
EP (1) EP1365749B1 (el)
JP (1) JP4990474B2 (el)
KR (1) KR100634571B1 (el)
CN (1) CN1237959C (el)
AT (1) ATE353009T1 (el)
AU (2) AU2002224317B2 (el)
BR (1) BRPI0113539B8 (el)
CA (1) CA2419993C (el)
CY (1) CY1106542T1 (el)
CZ (1) CZ299449B6 (el)
DE (2) DE01984557T1 (el)
DK (1) DK1365749T3 (el)
ES (1) ES2206081T3 (el)
HK (1) HK1056326A1 (el)
HU (1) HU229381B1 (el)
MX (1) MXPA03001762A (el)
NO (1) NO333369B1 (el)
PL (1) PL200398B1 (el)
PT (1) PT1365749E (el)
SI (1) SI1365749T1 (el)
TW (1) TW589199B (el)
WO (1) WO2002017855A2 (el)
ZA (1) ZA200301007B (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4226846B2 (ja) * 2002-06-07 2009-02-18 キャタレント・ジャパン株式会社 口腔内で崩壊可能なソフトカプセル剤
WO2005046727A2 (en) * 2003-11-12 2005-05-26 Ranbaxy Laboratories Limited Ibuprofen-containing soft gelatin capsules
US9241902B2 (en) * 2003-12-17 2016-01-26 R.P. Scherer Technologies, Llc Chewable soft capsules containing ungelatinized starch
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
WO2005063219A2 (en) * 2003-12-23 2005-07-14 Ranbaxy Laboratories Limited Ibuprofen-containing soft gelatin capsules
BRPI0506764A (pt) * 2004-01-09 2007-05-22 Wyeth Corp microemulsões para composições farmacêuticas
US20050249802A1 (en) * 2004-05-06 2005-11-10 The Procter & Gamble Company Softgel encapsulated pharmaceutical compositions comprising concentrated active ingredients
WO2005123133A1 (en) * 2004-06-18 2005-12-29 Ranbaxy Laboratories Limited A process for preparing ibuprofen soft gelatin capsules
CA2570524C (en) 2004-06-30 2013-01-15 Albemarle Corporation High ibuprofen content granules and their preparation and their use in pharmaceutical dosage forms
US20060088590A1 (en) * 2004-10-22 2006-04-27 Banner Pharmacaps, Inc. Non-blooming gelatin and non-gelatin formulations
US8231896B2 (en) * 2004-11-08 2012-07-31 R.P. Scherer Technologies, Llc Non-gelatin soft capsule system
US20070053868A1 (en) 2005-03-08 2007-03-08 Banner Pharmacaps, Inc. Solvent system for enhancing the solubility of pharmaceutical agents
US20080269334A1 (en) * 2005-09-19 2008-10-30 Albemarle Corporation Highly Concentrated Pourable Aqueous Solutions Of Potassium Ibuprofen, Their Preparation And Their Use
CN100404031C (zh) * 2006-03-13 2008-07-23 浙江万联药业有限公司 含葡萄糖酸锌、布洛芬和马来酸氯苯那敏的软胶囊组合物
EP2309988B1 (en) 2008-07-21 2015-11-25 SI Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
ES2363964B1 (es) 2009-11-20 2012-08-22 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados.
CA2690488C (en) 2010-01-19 2013-06-11 Accucaps Industries Limited Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof
CN104083339A (zh) * 2014-08-04 2014-10-08 人福普克药业（武汉）有限公司 萘普生钠软胶囊及其制备方法
CN107951857B (zh) * 2017-11-29 2019-12-24 浙江安宝药业有限公司 布洛芬软胶囊
CR20200552A (es) 2018-05-16 2021-05-13 Bayer Healthcare Llc Fórmula de suspención de alta concentración para medicamentos en cápsula de gel blanda paae resfriado y gripe
WO2019224832A1 (en) * 2018-05-25 2019-11-28 Strides Shasun Limited Process for preparing pharmaceutical compositions resulting in reduction in overall fill volume for use with soft gelatin formulations
CN108904465B (zh) * 2018-10-17 2021-02-26 石药集团恩必普药业有限公司 一种布洛芬药物制剂组合物及其制备方法
CN109820833B (zh) * 2019-04-01 2022-02-01 人福普克药业（武汉）有限公司 一种快速溶出的布洛芬软胶囊及其制备方法
EP3958852A4 (en) * 2019-04-26 2023-01-18 R.P. Scherer Technologies, LLC COMPOSITION OF NAPROXEN IN SOFT MINI-CAPSULE
US20220233452A1 (en) * 2021-01-25 2022-07-28 R.P. Scherer Technologies, Llc Mini softgel naproxen composition

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2118040A (en) 1982-02-15 1983-10-26 Hoechst Uk Ltd Oral anti-diabetic preparation
ATE57472T1 (de) 1984-03-14 1990-11-15 Jerome Corbiere Verfahren zum loesen von wirksubstanzen und auf diese weise erhaltene arzneimittel.
DE3437599C2 (de) 1984-10-13 1987-04-16 Dolorgiet GmbH & Co KG, 5205 St Augustin Ibuprofen enthaltende Weichgelatinekapseln
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation
JP3121080B2 (ja) 1991-12-19 2000-12-25 アール・ピー・シーラー コーポレイション カプセル封入用溶液
US5376688A (en) 1992-12-18 1994-12-27 R. P. Scherer Corporation Enhanced solubility pharmaceutical solutions
WO1998038987A1 (en) * 1997-03-03 1998-09-11 Sanofi-Synthelabo Pharmaceutical formulations containing poorly soluble drug substances

Also Published As

Publication number Publication date
KR100634571B1 (ko) 2006-10-16
ATE353009T1 (de) 2007-02-15
JP4990474B2 (ja) 2012-08-01
TW589199B (en) 2004-06-01
NO20030897L (no) 2003-02-26
ES2206081T3 (es) 2007-10-01
HUP0401224A2 (hu) 2004-11-29
DE60126433T2 (de) 2007-11-15
HK1056326A1 (en) 2004-02-13
PL200398B1 (pl) 2009-01-30
EP1365749A2 (en) 2003-12-03
BRPI0113539B8 (pt) 2021-05-25
CN1237959C (zh) 2006-01-25
SI1365749T1 (sl) 2007-06-30
NO333369B1 (no) 2013-05-13
ZA200301007B (en) 2004-02-13
HU229381B1 (en) 2013-11-28
DE01984557T1 (de) 2004-04-22
EP1365749B1 (en) 2007-01-31
JP2004526664A (ja) 2004-09-02
US6387400B1 (en) 2002-05-14
AU2431702A (en) 2002-03-13
EP1365749A4 (en) 2005-09-07
CA2419993C (en) 2008-12-23
BRPI0113539B1 (pt) 2017-05-09
CZ299449B6 (cs) 2008-07-30
CA2419993A1 (en) 2002-03-07
DE60126433D1 (de) 2007-03-22
MXPA03001762A (es) 2003-06-04
PL365752A1 (en) 2005-01-10
KR20030041982A (ko) 2003-05-27
WO2002017855A3 (en) 2003-09-25
HUP0401224A3 (en) 2008-04-28
PT1365749E (pt) 2007-03-30
NO20030897D0 (no) 2003-02-26
BR0113539A (pt) 2003-07-15
CN1477953A (zh) 2004-02-25
AU2002224317B2 (en) 2004-09-02
DK1365749T3 (da) 2007-06-04
WO2002017855A2 (en) 2002-03-07
ES2206081T1 (es) 2004-05-16

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