CO4910164A1 - Derivados de naftiridinas - Google Patents
Derivados de naftiridinasInfo
- Publication number
- CO4910164A1 CO4910164A1 CO97063263A CO97063263A CO4910164A1 CO 4910164 A1 CO4910164 A1 CO 4910164A1 CO 97063263 A CO97063263 A CO 97063263A CO 97063263 A CO97063263 A CO 97063263A CO 4910164 A1 CO4910164 A1 CO 4910164A1
- Authority
- CO
- Colombia
- Prior art keywords
- formula
- compound
- amino
- free
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Una 8-aril-1,7-naftiridina o un óxido-N de la misma, en forma delibre o de sal. Un compuesto, de acuerdo con la reivindicación 1, de la fórmula I donde R1 es fenilo, bencilo, 3-nitrofenilo, 3-clorofenilo, 3-cianofenilo, 3-(tetrazolil)fenilo, benzofurazanilo, o benzotiofurazanilo; R2 es hidroxi, amino, trifluometanosulfonilo, alilo, alquilo, alquenilo, alquinilo, alcoxi, arilo, aralquilo, ariloxi, amino, arilamino, diarilamino alcamino, dialcamino, alcarilo, arilamido, o alcamido, y los ésteres, amidas y óxidos-N del mismo; en forma libre o de sal de adición ácida.Un compuesto, de acuerdo con la reivindicación 3, de la fórmula II donde n es cero o uno R7 es hidroxi, amino, alquilo C1-4 , o alcoxi C1-4 , - 2 -preferentemente hidroxi o amino; y R3 es H y R4 es nitro, halo (por ejemplo 1-tetrazolilo), y R5 y R6 en conjunto, forman un enlace adicional, o R3 , R4 , R5 y R6 , en conjunto, son =N-O-N= o =N-S-N=; y los ésteres, amidas y óxidos del mismo; en forma libre o de una sal farmacéuticamente aceptable.Un procedimiento para la preparación de un compuesto de la fórmula II, de acuerdo con la reivindicación 4, el cual comprende la reacción de un compuesto de la fórmula VI donde R3 , R4 , R5 R6 , son tal como se las define en la reivindicación 4 y X es un grupo saliente, con un compuesto de la fórmula VII donde R7 es tal como se la definiera en la reivindicación 4 y X´ es un grupo saliente, y la recuperación del compuesto de la fórmula II obtenido de esta manera en forma libre o de sal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9622386.2A GB9622386D0 (en) | 1996-10-28 | 1996-10-28 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4910164A1 true CO4910164A1 (es) | 2000-04-24 |
Family
ID=10802050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO97063263A CO4910164A1 (es) | 1996-10-28 | 1997-10-28 | Derivados de naftiridinas |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6136821A (es) |
| EP (1) | EP0934320B1 (es) |
| JP (1) | JP4451496B2 (es) |
| KR (1) | KR100524329B1 (es) |
| CN (1) | CN1103773C (es) |
| AR (1) | AR009128A1 (es) |
| AT (1) | ATE236155T1 (es) |
| AU (1) | AU724471B2 (es) |
| BR (1) | BR9713280B1 (es) |
| CA (1) | CA2269946C (es) |
| CO (1) | CO4910164A1 (es) |
| CZ (1) | CZ146699A3 (es) |
| DE (1) | DE69720493T2 (es) |
| DK (1) | DK0934320T3 (es) |
| ES (1) | ES2196377T3 (es) |
| GB (1) | GB9622386D0 (es) |
| HK (1) | HK1022305A1 (es) |
| HU (1) | HUP9904204A3 (es) |
| ID (1) | ID18623A (es) |
| IL (2) | IL129502A0 (es) |
| MY (1) | MY132642A (es) |
| NO (1) | NO312677B1 (es) |
| NZ (1) | NZ335363A (es) |
| PE (1) | PE10899A1 (es) |
| PL (1) | PL189280B1 (es) |
| PT (1) | PT934320E (es) |
| SI (1) | SI0934320T1 (es) |
| SK (1) | SK283562B6 (es) |
| TR (1) | TR199900920T2 (es) |
| TW (1) | TW399052B (es) |
| WO (1) | WO1998018796A1 (es) |
| ZA (1) | ZA979593B (es) |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6534519B1 (en) | 1999-01-15 | 2003-03-18 | Altana Pharma Ag | Phenanthridine-N-oxides with PDE-IV inhibiting activity |
| CA2359404A1 (en) * | 1999-01-15 | 2000-07-20 | Beate Gutterer | Phenanthridine-n-oxides with pde-iv inhibiting activity |
| DE60043318D1 (de) | 1999-08-21 | 2010-01-14 | Nycomed Gmbh | Synergistische kombination von pumafentrine und salmeterol |
| US6953774B2 (en) | 2000-08-11 | 2005-10-11 | Applied Research Systems Ars Holding N.V. | Methods of inducing ovulation |
| JP2004520386A (ja) | 2001-01-31 | 2004-07-08 | ファイザー・プロダクツ・インク | Ｐｄｅ４アイソザイムの阻害剤として有用なニコチンアミドビアリール誘導体 |
| CN1489588A (zh) | 2001-01-31 | 2004-04-14 | �Ʒ� | 用作pde4同功酶抑制剂的噻唑基,噁唑基,吡咯基,和咪唑基羧酸酰胺衍生物 |
| NZ526531A (en) | 2001-01-31 | 2005-02-25 | Pfizer Prod Inc | Ether derivatives useful as inhibitors of phosphodiesterase type IV (PDE4) isozymes |
| US7250518B2 (en) | 2001-01-31 | 2007-07-31 | Pfizer Inc. | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes |
| EP1389467B1 (en) * | 2001-05-23 | 2013-07-03 | Mitsubishi Tanabe Pharma Corporation | Therapeutic composition for the regenerative treatment of cartilage diseases |
| JP4484515B2 (ja) * | 2001-10-16 | 2010-06-16 | メモリ ファーマセチカル コーポレーション | 神経病症候群の治療の為のｐｄｅ−４阻害剤としての、４−（４−アルコキシ−３−ヒドロキシフェニル）−２−ピロリディン誘導体。 |
| AR037517A1 (es) * | 2001-11-05 | 2004-11-17 | Novartis Ag | Derivados de naftiridinas, un proceso para su preparacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento para el tratamiento de una enfermedad inflamatoria |
| PT1463493E (pt) | 2001-12-14 | 2008-01-04 | Serono Lab | Método para induzir a ovulação utilizando um modulador de nível camp não polipeptídico |
| NZ540138A (en) | 2002-11-19 | 2008-07-31 | Memory Pharm Corp | Pyridine n-oxide compounds as phosphodiesterase 4 inhibitors |
| GB0229281D0 (en) * | 2002-12-16 | 2003-01-22 | Novartis Ag | Organic compounds |
| JP2006523710A (ja) * | 2003-04-16 | 2006-10-19 | メモリー・ファーマシューティカルズ・コーポレイション | ホスホジエステラーゼ４インヒビター |
| CA2522687A1 (en) * | 2003-04-18 | 2004-11-04 | Memory Pharmaceuticals Corporation | Pyrazole derivatives as phosphodiesterase 4 inhibitors |
| TW200519106A (en) | 2003-05-02 | 2005-06-16 | Novartis Ag | Organic compounds |
| MY141255A (en) | 2003-12-11 | 2010-03-31 | Memory Pharm Corp | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs |
| GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
| US20090042951A1 (en) * | 2004-02-20 | 2009-02-12 | Robert Danziger | Blood Pressure Reduction in Salt-Sensitive Hypertension |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| JP2008503591A (ja) * | 2004-06-22 | 2008-02-07 | ライジェル ファーマシューティカルズ， インコーポレイテッド | ユビキチンリガーゼ阻害剤 |
| WO2006031959A1 (en) * | 2004-09-14 | 2006-03-23 | Novartis Ag | Process for the preparation of 6, 8-substituted `1, 7 naphthpyridin derivatives by reacting the 8-halo-`1, 7 naphthpyridin-derivate with an organic boronic acid derivatives and intermadiates of this process |
| EP1799673A1 (en) * | 2004-10-15 | 2007-06-27 | Memory Pharmaceuticals Corporation | Pyrazole derivatives as phosphodiesterase 4 inhibitors |
| AU2005295350A1 (en) * | 2004-10-20 | 2006-04-27 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors |
| GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
| GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
| GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
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| GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
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| EP2258357A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| EP2275095A3 (en) | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| US20080221110A1 (en) * | 2005-10-21 | 2008-09-11 | Nathalie Cailleau | Compounds |
| JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス，インコーポレイティド | Ｐｄｅ阻害による神経新生の調節 |
| KR20080049113A (ko) | 2005-10-21 | 2008-06-03 | 노파르티스 아게 | Ｉｌ-13에 대항한 인간 항체 및 치료적 용도 |
| CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| EP1963324B1 (en) | 2005-12-22 | 2010-04-21 | Glaxo Group Limited | Heterocyclic compounds, their preparation and their use as antibacterials |
| GB0526244D0 (en) | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| PT2322525E (pt) | 2006-04-21 | 2013-12-26 | Novartis Ag | Derivados de purina para utilização como agonistas do recetor de adenosina a2a |
| AU2007249435A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
| EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
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| US20090286779A1 (en) | 2006-09-29 | 2009-11-19 | Novartis Ag | Pyrazolopyrimidines as lipid kinase inhibitors |
| EP2089393A1 (en) | 2006-10-30 | 2009-08-19 | Novartis AG | Heterocyclic compounds as antiinflammatory agents |
| PT2104535E (pt) | 2007-01-10 | 2011-03-31 | Irm Llc | Compostos e composições como inibidores da protease de activação de canal |
| EA200901489A1 (ru) | 2007-05-07 | 2010-04-30 | Новартис Аг | Органические соединения |
| PE20091096A1 (es) | 2007-12-10 | 2009-08-25 | Novartis Ag | Compuestos organicos |
| US8431578B2 (en) | 2008-01-11 | 2013-04-30 | Novartis Ag | Organic compounds |
| US8268834B2 (en) | 2008-03-19 | 2012-09-18 | Novartis Ag | Pyrazine derivatives that inhibit phosphatidylinositol 3-kinase enzyme |
| MX2010013675A (es) | 2008-06-10 | 2011-02-15 | Novartis Ag | Derivados de pirazina como bloqueadores del canal de sodio epitelial. |
| SI2391366T1 (sl) | 2009-01-29 | 2013-01-31 | Novartis Ag | Substituirani benzimidazoli za zdravljenje astrocitomov |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| US8389526B2 (en) | 2009-08-07 | 2013-03-05 | Novartis Ag | 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives |
| US8497368B2 (en) | 2009-08-12 | 2013-07-30 | Novartis Ag | Heterocyclic hydrazone compounds |
| ES2709108T3 (es) | 2009-08-17 | 2019-04-15 | Intellikine Llc | Compuestos heterocíclicos y usos de los mismos |
| EA201200318A1 (ru) | 2009-08-20 | 2012-09-28 | Новартис Аг | Гетероциклические оксимы |
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| US8247436B2 (en) | 2010-03-19 | 2012-08-21 | Novartis Ag | Pyridine and pyrazine derivative for the treatment of CF |
| CA2804744C (en) | 2010-07-14 | 2019-05-28 | Novartis Ag | Ip receptor agonist 1,8-naphthyridinyl and 7,8-dihydropyrido[3,2-b]pyrazinyl heterocyclic compounds |
| WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| US8637516B2 (en) | 2010-09-09 | 2014-01-28 | Irm Llc | Compounds and compositions as TRK inhibitors |
| US8372845B2 (en) | 2010-09-17 | 2013-02-12 | Novartis Ag | Pyrazine derivatives as enac blockers |
| US20130324526A1 (en) | 2011-02-10 | 2013-12-05 | Novartis Ag | [1,2,4] triazolo [4,3-b] pyridazine compounds as inhibitors of the c-met tyrosine kinase |
| WO2012116237A2 (en) | 2011-02-23 | 2012-08-30 | Intellikine, Llc | Heterocyclic compounds and uses thereof |
| JP5959541B2 (ja) | 2011-02-25 | 2016-08-02 | ノバルティス アーゲー | Ｔｒｋ阻害剤としてのピラゾロ［１，５−ａ］ピリジン |
| US8883819B2 (en) | 2011-09-01 | 2014-11-11 | Irm Llc | Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension |
| EA026655B1 (ru) | 2011-09-15 | 2017-05-31 | Новартис Аг | 6-ЗАМЕЩЕННЫЕ 3-(ХИНОЛИН-6-ИЛТИО)[1,2,4]ТРИАЗОЛО[4,3-a]ПИРИДИНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ c-MET ТИРОЗИНКИНАЗЫ |
| WO2013038373A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine amide derivatives |
| WO2013038390A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | N-substituted heterocyclyl carboxamides |
| WO2013038378A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine amide derivatives |
| WO2013038381A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine/pyrazine amide derivatives |
| US9034879B2 (en) | 2011-09-16 | 2015-05-19 | Novartis Ag | Heterocyclic compounds for the treatment of CF |
| EP2793893A4 (en) | 2011-11-23 | 2015-07-08 | Intellikine Llc | IMPROVED TREATMENT REGIMES USING MTOR INHIBITORS |
| WO2013106547A1 (en) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| ES2565826T3 (es) | 2012-01-13 | 2016-04-07 | Novartis Ag | Pirroles fusionados como agonistas del receptor IP para el tratamiento de hipertensión arterial pulmonar (PAH) y trastornos relacionados |
| US8809340B2 (en) | 2012-03-19 | 2014-08-19 | Novartis Ag | Crystalline form |
| EP3964513A1 (en) | 2012-04-03 | 2022-03-09 | Novartis AG | Combination products with tyrosine kinase inhibitors and their use |
| JP5907006B2 (ja) * | 2012-09-04 | 2016-04-20 | エヌ・イーケムキャット株式会社 | ビフェニル化合物の合成方法 |
| JP5907005B2 (ja) * | 2012-09-04 | 2016-04-20 | エヌ・イーケムキャット株式会社 | ビフェニル化合物の合成方法 |
| EP2956455B1 (en) | 2013-02-13 | 2017-05-17 | Novartis AG | Ip receptor agonist heterocyclic compounds |
| US9073921B2 (en) | 2013-03-01 | 2015-07-07 | Novartis Ag | Salt forms of bicyclic heterocyclic derivatives |
| JP2016512835A (ja) | 2013-03-15 | 2016-05-09 | インテリカイン， エルエルシー | キナーゼ阻害剤の組み合わせ及びそれらの使用 |
| WO2015084804A1 (en) | 2013-12-03 | 2015-06-11 | Novartis Ag | Combination of mdm2 inhibitor and braf inhibitor and their use |
| MX2016013983A (es) | 2014-04-24 | 2017-04-06 | Novartis Ag | Derivados de pirazina como inhibidores de fosfatidil-inositol-3-ci nasa. |
| CN106458979B (zh) | 2014-04-24 | 2020-03-27 | 诺华股份有限公司 | 作为磷脂酰肌醇3-激酶抑制剂的氨基吡嗪衍生物 |
| AU2014391605A1 (en) | 2014-04-24 | 2016-10-27 | Novartis Ag | Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors |
| US9741941B2 (en) | 2014-04-29 | 2017-08-22 | Universal Display Corporation | Organic electroluminescent materials and devices |
| WO2016011658A1 (en) | 2014-07-25 | 2016-01-28 | Novartis Ag | Combination therapy |
| US10195208B2 (en) | 2014-07-31 | 2019-02-05 | Novartis Ag | Combination therapy |
| WO2020250116A1 (en) | 2019-06-10 | 2020-12-17 | Novartis Ag | Pyridine and pyrazine derivative for the treatment of cf, copd, and bronchiectasis |
| CN114341132A (zh) | 2019-08-28 | 2022-04-12 | 诺华股份有限公司 | 经取代的1,3-苯基杂芳基衍生物及其在治疗疾病中的用途 |
| TW202140550A (zh) | 2020-01-29 | 2021-11-01 | 瑞士商諾華公司 | 使用抗ｔｓｌｐ抗體治療炎性或阻塞性氣道疾病之方法 |
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-
1996
- 1996-10-28 GB GBGB9622386.2A patent/GB9622386D0/en active Pending
-
1997
- 1997-10-16 TW TW086115176A patent/TW399052B/zh not_active IP Right Cessation
- 1997-10-24 IL IL12950297A patent/IL129502A0/xx not_active IP Right Cessation
- 1997-10-24 PT PT97948803T patent/PT934320E/pt unknown
- 1997-10-24 WO PCT/EP1997/005898 patent/WO1998018796A1/en not_active Application Discontinuation
- 1997-10-24 TR TR1999/00920T patent/TR199900920T2/xx unknown
- 1997-10-24 AT AT97948803T patent/ATE236155T1/de not_active IP Right Cessation
- 1997-10-24 BR BRPI9713280-2A patent/BR9713280B1/pt not_active IP Right Cessation
- 1997-10-24 JP JP52002898A patent/JP4451496B2/ja not_active Expired - Fee Related
- 1997-10-24 SK SK557-99A patent/SK283562B6/sk unknown
- 1997-10-24 ES ES97948803T patent/ES2196377T3/es not_active Expired - Lifetime
- 1997-10-24 HU HU9904204A patent/HUP9904204A3/hu unknown
- 1997-10-24 DE DE69720493T patent/DE69720493T2/de not_active Expired - Lifetime
- 1997-10-24 KR KR10-1999-7003661A patent/KR100524329B1/ko not_active IP Right Cessation
- 1997-10-24 SI SI9730541T patent/SI0934320T1/xx unknown
- 1997-10-24 AU AU69084/98A patent/AU724471B2/en not_active Ceased
- 1997-10-24 CZ CZ991466A patent/CZ146699A3/cs unknown
- 1997-10-24 CA CA002269946A patent/CA2269946C/en not_active Expired - Fee Related
- 1997-10-24 DK DK97948803T patent/DK0934320T3/da active
- 1997-10-24 CN CN97199186A patent/CN1103773C/zh not_active Expired - Fee Related
- 1997-10-24 EP EP97948803A patent/EP0934320B1/en not_active Expired - Lifetime
- 1997-10-24 PE PE1997000953A patent/PE10899A1/es not_active Application Discontinuation
- 1997-10-24 NZ NZ335363A patent/NZ335363A/xx unknown
- 1997-10-24 US US09/297,245 patent/US6136821A/en not_active Expired - Fee Related
- 1997-10-24 PL PL97332738A patent/PL189280B1/pl not_active IP Right Cessation
- 1997-10-24 AR ARP970104916A patent/AR009128A1/es unknown
- 1997-10-27 ID IDP973530A patent/ID18623A/id unknown
- 1997-10-27 MY MYPI97005054A patent/MY132642A/en unknown
- 1997-10-27 ZA ZA9709593A patent/ZA979593B/xx unknown
- 1997-10-28 CO CO97063263A patent/CO4910164A1/es unknown
-
1999
- 1999-04-19 IL IL129502A patent/IL129502A/en unknown
- 1999-04-21 NO NO19991903A patent/NO312677B1/no unknown
-
2000
- 2000-02-11 HK HK00100828A patent/HK1022305A1/xx not_active IP Right Cessation
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