CN112156037A - Skin-care soothing composition, makeup removing lotion and preparation method thereof - Google Patents
Skin-care soothing composition, makeup removing lotion and preparation method thereof Download PDFInfo
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- CN112156037A CN112156037A CN202011228020.6A CN202011228020A CN112156037A CN 112156037 A CN112156037 A CN 112156037A CN 202011228020 A CN202011228020 A CN 202011228020A CN 112156037 A CN112156037 A CN 112156037A
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- skin
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- 239000000203 mixture Substances 0.000 title claims abstract description 58
- 239000006210 lotion Substances 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title description 13
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 83
- 239000002994 raw material Substances 0.000 claims abstract description 55
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims abstract description 41
- 229940032094 squalane Drugs 0.000 claims abstract description 41
- 150000001413 amino acids Chemical class 0.000 claims abstract description 32
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- 238000000855 fermentation Methods 0.000 claims abstract description 31
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- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 claims abstract description 30
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 claims abstract description 30
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 claims abstract description 30
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- BBAFBDLICMHBNU-MFZOPHKMSA-N N-(2-hydroxyoctadecanoyl)-4-hydroxysphinganine Chemical compound CCCCCCCCCCCCCCCCC(O)C(=O)N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC BBAFBDLICMHBNU-MFZOPHKMSA-N 0.000 claims description 19
- ATGQXSBKTQANOH-UWVGARPKSA-N N-oleoylphytosphingosine Chemical compound CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(=O)CCCCCCC\C=C/CCCCCCCC ATGQXSBKTQANOH-UWVGARPKSA-N 0.000 claims description 19
- MIUIRGGKIICMBP-NFOZDHADSA-N [27-oxo-27-[[(2s,3s,4r)-1,3,4-trihydroxyoctadecan-2-yl]amino]heptacosyl] octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)[C@H](O)CCCCCCCCCCCCCC MIUIRGGKIICMBP-NFOZDHADSA-N 0.000 claims description 19
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 19
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- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 12
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims description 12
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 claims description 10
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- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims description 10
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- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims description 5
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- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 claims description 5
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- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 4
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- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 description 1
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- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/14—Preparations for removing make-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to a skin-care and soothing composition, which is prepared from ceramide, amino acid, squalane and a lysate of a yeast fermentation product of fission yeast as raw materials, and other auxiliary materials through multiple mixing, emulsification, homogenization and other methods. The invention has the beneficial effects that: the skin care and soothing composition mainly adopts ceramide, amino acid, squalane and a lysate of a yeast fermentation product of fission yeast as a 3+1 barrier relieving formula, selects components (ceramide, amino acid and squalane) from a skin lipid membrane, keratinocytes and lipid of a barrier system to form a bionic barrier system, matches probiotics to regulate the microecological balance of skin, enhances the skin immunity, is mild and soothing and sensitive red itch, and is suitable for any product; the prepared skin-care soft makeup removing lotion can reduce skin injury in the makeup removing process, is suitable for sensitive skin, protects the skin, promotes the generation of a skin protection barrier, enables the skin to reappear smooth and tender and has the effect of maintaining the skin stably.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a skin-care soothing composition for makeup removing lotion, the makeup removing lotion and a preparation method thereof.
Background
People often need make-up in daily life and work, especially the female white collar makes-up frequently, if do not do the makeup removal work, remaining makeup and color can deposit on the skin, make skin dull and not glossy, the dirt that deposits on the surface still can block the pore, long ago, skin can become coarse and dull, the pore is thick, appear blackhead acne, closed pox scheduling problem.
In the prior art, the makeup removing lotion easily causes allergy in the makeup removing process and destroys the microecological balance of skin; most makeup removing products have incomplete makeup removal, poor moisturizing effect, low safety and easy damage to skin.
In view of this, this patent is filed.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides the skin-care soft and moist cleansing milk and the preparation method thereof.
The invention aims to provide a skin-care soothing composition for makeup removing cream.
The invention also aims to provide the skin-care soft-moistening makeup-removing cream prepared from the composition.
The invention further aims to provide a preparation method of the skin-care soft and moist cleansing milk.
The skin care soothing composition for the makeup removing cream according to the embodiment of the present invention is prepared from the following raw materials: ceramide, amino acid, squalane and a yeast fermentation lysate of the second split yeast.
The skin-care soothing composition for the makeup removing cream comprises the following main materials in parts by weight: 1.1 to 2.6 parts by weight of ceramide, 0.6 to 1.7 parts by weight of amino acid, 0.5 to 1.0 part by weight of squalane and 0.2 to 0.6 part by weight of a split yeast fermentation product lysate.
The skin care soothing composition for makeup removing cream according to the embodiment of the present invention, wherein the amino acids include arginine and glycine.
The skin care soothing composition for makeup removing cream according to the embodiment of the present invention, wherein the ceramide comprises ceramide 1, ceramide 3 and ceramide 6.
The skin care and soothing composition for the makeup removing cream according to the embodiment of the invention comprises the following components in parts by weight: 0.3-0.7 part of ceramide 1, 0.3-0.7 part of ceramide 3 and 0.5-1.2 parts of ceramide 6, wherein the amino acids comprise the following components in parts by weight: 0.3-0.9 weight part of arginine and 0.3-0.8 weight part of glycine.
According to the skin-care soft makeup removing milk, the skin-care soft makeup removing milk further comprises main materials and auxiliary materials, wherein the main materials are ceramide, amino acid, squalane and lysate of a yeast fermentation product of fission yeast, and the auxiliary materials comprise glyceryl cocoate, caprylic/capric triglyceride, an iceland lichen extract, arginine and glycine.
According to the skin-care soft makeup removing lotion provided by the embodiment of the invention, furthermore, the skin-care soft makeup removing lotion is prepared from the following raw materials in parts by weight:
phase A: 3.0-5.0 parts of PEG-7 glyceryl cocoate, 4.0-8.0 parts of caprylic/capric triglyceride, 0.1-0.2 part of isohexadecane, 0.1-0.2 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer and 0.5-1.0 part of squalane;
phase B: 80.0-88.0 parts of water, 0.2-0.3 part of glycerol, 0.3-0.9 part of arginine and 0.3-0.8 part of glycine;
and C phase: 0.5-1.2 parts of ceramide 6, 0.3-0.7 part of ceramide 3, 0.3-0.7 part of ceramide 1, 0.2-0.6 part of schizosaccharomyces cerevisiae fermentation product lysate, 0.4-0.6 part of iceland lichen extract, 0.1-0.3 part of asiatic pennywort leaf extract and 0.1-0.2 part of polysorbate-80. The Redo skin-conditioning soft cleansing cream prepared from the raw materials is suitable for dry and sensitive skin.
According to the skin-care soft makeup removing lotion provided by the embodiment of the invention, furthermore, the skin-care soft makeup removing lotion is prepared from the following raw materials in parts by weight:
phase A: 3.0-5.0 parts of PEG-7 glyceryl cocoate, 4.0-8.0 parts of caprylic/capric triglyceride and 0.5-1.0 part of squalane;
phase B: 80.0-88.0 parts of water, 0.3-0.9 part of arginine and 0.3-0.8 part of glycine;
and C phase: 0.5-1.2 parts of ceramide 6, 0.3-0.7 part of ceramide 3, 0.3-0.7 part of ceramide 1, 0.2-0.6 part of schizosaccharomyces cerevisiae fermentation product lysate, 0.4-0.6 part of iceland lichen extract, 0.1-0.3 part of perilla extract and 0.1-0.2 part of polysorbate-80. The Redo skin care cleansing and cleansing milk prepared from the raw materials is suitable for oil-sensitive skin.
The preparation method of the skin-conditioning soft makeup remover according to the embodiment of the invention comprises the following steps:
(1) adding all the raw materials in the phase A into an oil phase pot, stirring and heating until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) adding all the raw materials in the phase B into a water phase pot, stirring and heating, uniformly mixing to form a phase B mixture, and keeping the temperature for later use;
(3) pumping the phase A mixture obtained in the step (1) into an emulsifying pot, adding the phase B mixture obtained in the step (2), emulsifying and homogenizing for 8-12 minutes, and uniformly stirring to form a phase A and phase B mixture; cooling while degassing, cooling to 40-45 deg.C, adding all the raw materials of phase C, and stirring; cooling to 25-35 deg.C to obtain the final product.
According to the preparation method of the skin-care soft makeup removing lotion, in the step (1), all the raw materials in the phase A are added into an oil phase pot, stirred and heated to 75-80 ℃ until all the raw materials in the phase A are completely dissolved to be free of particles.
Further, in the step (2), all the raw materials in the phase B are added into a water phase pot, stirred and heated to 70-80 ℃.
Wherein in the step (3), the temperature of the emulsification and homogenization is 65-70 ℃.
The homogenization process of the invention adopts a vacuum homogenizing emulsifying machine to homogenize.
The water used in the invention is pure water.
The application method of the skin-care soft makeup removing lotion provided by the invention comprises the steps of pressing the skin-care soft makeup removing lotion on the palm of a hand, rubbing the palm open, smearing the skin-care soft makeup removing lotion on a part needing makeup removing, rubbing the part needing makeup removing lotion, and washing the part needing makeup removing lotion with clear water.
The main raw materials in the invention are ceramide, amino acid, squalane and lysate of fermentation product of yeast schizosaccharomyces. The 3+1 barrier relieving formula is creatively adopted by the applicant, components (ceramide, amino acid and squalane) are selected from a skin lipid membrane, keratinocytes and lipid of a barrier system to form a bionic barrier system, probiotics are matched to regulate the microecological balance of skin, the immunity of the skin is enhanced, the skin is mild, and sensitive red itch is relieved.
The skin of a human body contains a natural protective barrier formed by a sebum membrane, keratinocytes, lipid and skin microecology, and a makeup removing product can damage the skin protective barrier to a certain extent in a makeup removing process, and the 3+1 composition disclosed by the invention can promote the generation of the original protective barrier of the skin of people through the fusion of a certain technology, balance the skin surface ecology and further reduce the damage of makeup removal to the skin of people.
Ceramide is a lipid naturally present in the skin, which forms a water barrier on the skin surface, better protecting the skin, and making it moist and tender. Ceramides are composed of a number of components, 1, 3, 6, which play different roles: ceramide 1 mainly plays a role in repairing a sebum membrane, can improve the barrier function of the skin surface layer, reduces the loss of water and finally achieves the moisturizing effect; ceramide 3 can maintain the water retention degree of the skin, repair dry and damaged skin and help the renewal of a natural protective layer of the skin; ceramide 6 helps the stratum corneum of the skin to metabolize rapidly, making the skin smoother. The invention adopts three kinds of ceramide (ceramide 1, ceramide 3 and ceramide 6 II) and triple ceramide composite essence which has the same structure with the ceramide (intercellular lipid) of a human body, supplements the intercellular lipid in the stratum corneum, can form a barrier effect firstly, avoids the damage of harmful factors to the skin and better protects the skin; secondly, the adhesive has an adhesive effect, and can increase the adhesive force between keratinocytes, thereby improving the symptoms of dry skin and desquamation; thirdly, the skin moisturizing cream has good moisturizing effect, and can prevent and relieve the phenomena of dry, chapped and peeled skin; fourthly, the skin care product has good anti-aging effect, can prevent the formation of wrinkles, can also fade fine lines, densely repairs natural skin lipid membranes of the skin and promotes the regeneration of the skin lipid membranes.
Amino acids: as a component of keratinocytes, the composition promotes the generation of keratinocytes and enhances barrier immunity. It can be well absorbed by skin, and has good effects of moisturizing, softening skin, removing wrinkle, whitening, refreshing, etc. The amino acid can help activate cells, promote metabolism of skin and blood circulation, has the efficacy of high-efficiency moisture retention, and helps the skin to effectively retain moisture and replenish water. It has better transparent effect than common hyaluronic acid, can smooth dry lines and fine lines, and helps skin resist wrinkles and effectively resist aging.
Squalane/squalene, is mainly present in the unsaponifiable fraction of shark liver oil, and is present in minor amounts in olive oil, rice bran oil, wheat germ oil, yeast and human fats. The squalane adopted in the invention is pure natural squalane extracted from olive oil (olive), has high affinity, is easily integrated with sebum of skin, and balances lipid.
Squalane is a component existing in the skin, has particularly good skin-friendly property, can be highly compatible with sebum secreted by the skin, forms a breathable protective film on the surface layer of the skin, and plays a role in moisturizing and moistening the skin; the skin dryness can be effectively relieved, and the elasticity and the fullness of the skin can be maintained; the squalane has good permeability, and can enter the skin, supplement cell lipid, and nourish the skin. After the skin is massaged by squalane, the skin becomes soft, moist and elastic, which is the result of squalane penetrating into the skin to play a role.
The invention also has a microbial film of probiotic composition: and probiotics are added to adjust the flora balance on the surface of the skin and the microecological balance of the skin. The invention adopts the cell lysate of the German CLR binary fission yeast, has the activity of resisting immunosuppression, can promote DNA repair and adjust the microecological balance of skin. The yeast schizolysis is obtained by decomposing active bacteria cells, and has a structure similar to biology naturally, such as cytoplasm, cell wall and polysaccharide complex, which means that the yeast schizosaccharomyces contains vitamins, minerals and amino acids for nourishing cells, and has the functions of preventing aging due to the fact that the yeast schizosaccharomyces contains beneficial skin care molecules required by biological cells, is beneficial to permeating skin barriers, deeply repairs muscle base injuries and protects against injuries caused by ultraviolet rays. The lysate of the yeast fermentation product has strong anti-immunosuppression activity, can effectively protect the skin, is not damaged by ultraviolet rays, can promote DNA repair, and helps to prevent the aging of epidermis and dermis. The yeast fermentation product lysate can generate micromolecules which comprise vitamin B group, mineral substances, amino acids and the like and are beneficial to skin care, is high-quality yeast essence which is very suitable for skin care, can strengthen the metabolism of cuticle, capture free radicals, inhibit the peroxidation of lipid, and has the functions of whitening and resisting aging. The product is rich in nutrients, and has skin nourishing effect.
Compared with the prior art, the invention has the following beneficial effects:
(1) the skin care and soothing composition mainly adopts ceramide, amino acid, squalane and a lysate of a yeast fermentation product of fission yeast as a 3+1 barrier relieving formula, selects components (ceramide, amino acid and squalane) from a skin lipid membrane, keratinocytes and lipid of a barrier system to form a bionic barrier system, matches probiotics to regulate the microecological balance of skin, enhances the skin immunity, is mild and soothing and sensitive red itch, and is suitable for any product; the prepared skin-care soft makeup removing lotion can reduce skin injury in the makeup removing process, is suitable for sensitive skin, protects the skin, promotes the generation of a skin protection barrier, enables the skin to reappear smooth and tender and has the effect of maintaining the skin stably;
(2) the invention enhances the skin resistance from the skin origin by supplementing essential important components of the horny layer, and has safer property and no toxic or side effect on the damage of the washing chemical reagent to the skin.
(3) The skin-care soft and moist cleansing milk disclosed by the invention is reasonable in raw material matching, can effectively clean cosmetics on the surface of skin, is good in cleansing effect and cannot cause skin allergy;
(4) ceramide mainly penetrates into a sebum membrane, amino acid mainly penetrates into and repairs glial cells, squalane penetrates into and protects the sebum membrane and lipid, and the lysate of the yeast schizosaccharomyces cerevisiae fermentation product regulates the skin microecology.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be described in detail below. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the examples given herein without any inventive step, are within the scope of the present invention.
The raw materials used in the present invention are all commercially available raw materials.
In some more specific embodiments, the skin-care soothing composition for makeup removing milk is prepared from the following raw materials and auxiliary materials, wherein the raw materials comprise main materials and auxiliary materials, the main materials comprise ceramide, amino acid, squalane and yeast dehiscence product lysate, and the main materials comprise the following components in parts by weight: 1.1 to 2.6 parts by weight of ceramide, 0.6 to 1.7 parts by weight of amino acid, 0.5 to 1.0 part by weight of squalane and 0.2 to 0.6 part by weight of a split yeast fermentation product lysate, the ceramide comprising in parts by weight: 0.3-0.7 part of ceramide 1, 0.3-0.7 part of ceramide 3 and 0.5-1.2 parts of ceramide 6, wherein the amino acids comprise the following components in parts by weight: 0.3-0.9 weight part of arginine and 0.3-0.8 weight part of glycine.
In some more specific embodiments, the skin-conditioning soft makeup remover is prepared from the following raw materials in parts by weight:
phase A: 3.0-5.0 parts of PEG-7 glyceryl cocoate, 4.0-8.0 parts of caprylic/capric triglyceride, 0.1-0.2 part of isohexadecane, 0.1-0.2 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer and 0.5-1.0 part of squalane;
phase B: 80.0-88.0 parts of water, 0.2-0.3 part of glycerol, 0.3-0.9 part of arginine and 0.3-0.8 part of glycine;
and C phase: 0.5-1.2 parts of ceramide 6, 0.3-0.7 part of ceramide 3, 0.3-0.7 part of ceramide 1, 0.2-0.6 part of schizosaccharomyces cerevisiae fermentation product lysate, 0.4-0.6 part of iceland lichen extract, 0.1-0.3 part of asiatic pennywort leaf extract and 0.1-0.2 part of polysorbate-80.
In other more specific embodiments, the skin-conditioning soft cleansing milk is prepared from the following raw materials in parts by weight: phase A: 3.0-5.0 parts of PEG-7 glyceryl cocoate, 4.0-8.0 parts of caprylic/capric triglyceride and 0.5-1.0 part of squalane;
phase B: 80.0-88.0 parts of water, 0.3-0.9 part of arginine and 0.3-0.8 part of glycine;
and C phase: 0.5-1.2 parts of ceramide 6, 0.3-0.7 part of ceramide 3, 0.3-0.7 part of ceramide 1, 0.2-0.6 part of schizosaccharomyces cerevisiae fermentation product lysate, 0.4-0.6 part of iceland lichen extract, 0.1-0.3 part of perilla extract and 0.1-0.2 part of polysorbate-80.
Example 1
The embodiment provides a skin-care soothing composition for makeup removing cream, which comprises main materials and auxiliary materials, wherein the main materials are ceramide, amino acid, squalane and a lysate of a yeast fermentation product of fission yeast: 1.1g ceramide, 1.7g amino acid, 0.5g squalane and 0.6g two split yeast fermentation product lysate, the ceramide is: 0.3g ceramide 1, 0.3g ceramide 3 and 0.5g ceramide 6, the amino acids are: 0.9g arginine and 0.8g glycine.
Example 2
The embodiment provides a skin-care soothing composition for makeup removing cream, which comprises main materials and auxiliary materials, wherein the main materials are ceramide, amino acid, squalane and a lysate of a yeast fermentation product of fission yeast: 2.6g ceramide, 0.6g amino acid, 1.0g squalane and 0.2g two split yeast fermentation product lysate, the ceramide is: 0.7g ceramide 1, 0.7g ceramide 3 and 1.2g ceramide 6, the amino acids are: 0.3g arginine and 0.3g glycine.
A method of preparing a composition comprising the steps of:
(1) adding squalane into an oil phase pot, stirring and heating at 75 ℃ until the squalane is completely dissolved until no particles exist, uniformly mixing to form a phase A, and keeping the temperature for later use;
(2) adding amino acid into a water phase pot, adding water, stirring, heating to 75 ℃, uniformly mixing to form a phase B, and keeping the temperature for later use;
(3) and (2) pumping the phase A obtained in the step (1) into an emulsifying pot, adding the phase B obtained in the step (2), emulsifying and homogenizing at 70 ℃ for 12 minutes, cooling to 30 ℃, adding the lysate of the fermentation product of the yeast schizolysis product, and uniformly stirring to obtain the finished product.
Example 3
The embodiment provides a skin-care soft makeup removing lotion which is prepared from the following raw materials:
phase A: 5.0g of PEG-7 glyceryl cocoate, 8.0g of caprylic/capric triglyceride, 0.1g of isohexadecane, 0.2g of sodium acrylate/sodium acryloyldimethyl taurate copolymer and 0.5g of squalane;
phase B: 88.0g of water, 0.2g of glycerol, 0.9g of arginine and 0.3g of glycine;
and C phase: 1.2g ceramide 6, 0.3g ceramide 3, 0.7g ceramide 1, 0.2g schizosaccharomyces cerevisiae fermentation product lysate, 0.6g iceland lichen extract, 0.1g centella asiatica leaf extract, 0.2g polysorbate-80.
The preparation method comprises the following steps:
(1) adding all the raw materials in the phase A into an oil phase pot, stirring and heating until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) adding all the raw materials in the phase B into a water phase pot, stirring and heating, uniformly mixing to form a phase B mixture, and keeping the temperature for later use;
(3) pumping the phase A mixture obtained in the step (1) into an emulsifying pot, adding the phase B mixture obtained in the step (2), emulsifying and homogenizing for 12 minutes, and stirring uniformly to form a phase A and phase B mixture; cooling while degassing, cooling to 40 ℃, adding all the raw materials of the phase C, and uniformly stirring; cooling to 35 deg.C to obtain the final product.
Example 4
The embodiment provides a skin-care soft makeup removing lotion which is prepared from the following raw materials:
phase A: 3.0g of PEG-7 glyceryl cocoate, 4.0g of caprylic/capric triglyceride, 0.2g of isohexadecane, 0.1g of sodium acrylate/sodium acryloyldimethyl taurate copolymer and 1.0g of squalane;
phase B: 88.0g of water, 0.3g of glycerol, 0.3g of arginine and 0.8g of glycine;
and C phase: 0.5g ceramide 6, 0.7g ceramide 3, 0.3g ceramide 1, 0.6g schizosaccharomyces cerevisiae fermentation product lysate, 0.4g iceland lichen extract, 0.3g centella asiatica leaf extract, 0.1g polysorbate-80.
The preparation method comprises the following steps:
(1) adding all the raw materials in the phase A into an oil phase pot, stirring and heating until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) adding all the raw materials in the phase B into a water phase pot, stirring and heating, uniformly mixing to form a phase B mixture, and keeping the temperature for later use;
(3) pumping the phase A mixture obtained in the step (1) into an emulsifying pot, adding the phase B mixture obtained in the step (2), emulsifying and homogenizing for 8 minutes, and stirring uniformly to form a phase A and phase B mixture; cooling while degassing, cooling to 45 ℃, adding all the raw materials of the phase C, and uniformly stirring; cooling to 25 deg.C to obtain the final product.
Example 5
The embodiment provides a skin-care soft makeup removing lotion which is prepared from the following raw materials:
phase A: 5.0g of PEG-7 glyceryl cocoate, 4.0g of caprylic/capric triglyceride and 1.0g of squalane;
phase B: 88.0g of water, 0.3g of arginine and 0.8g of glycine;
and C phase: 0.5g ceramide 6, 0.7g ceramide 3, 0.3g ceramide 1, 0.6g schizosaccharomyces cerevisiae fermentation product lysate, 0.4g iceland lichen extract, 0.3g perilla extract, 0.1g polysorbate-80.
The preparation method comprises the following steps:
(1) adding all the raw materials in the phase A into an oil phase pot, stirring and heating to 80 ℃ until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) adding all the raw materials in the phase B into a water phase pot, stirring and heating to 70 ℃, uniformly mixing to form a phase B mixture, and keeping the temperature for later use;
(3) pumping the phase A mixture obtained in the step (1) into an emulsifying pot, adding the phase B mixture obtained in the step (2), emulsifying and homogenizing at 65 ℃ for 12 minutes, and uniformly stirring to form a phase A and phase B mixture; cooling while degassing, cooling to 40 ℃, adding all the raw materials of the phase C, and uniformly stirring; cooling to 25 deg.C to obtain the final product.
Example 6
The embodiment provides a skin-care soft makeup removing lotion which is prepared from the following raw materials:
phase A: 3.0g of PEG-7 glyceryl cocoate, 8.0g of caprylic/capric triglyceride and 0.5g of squalane;
phase B: 80.0g of water, 0.9g of arginine and 0.3g of glycine;
and C phase: 1.2g ceramide 6, 0.3g ceramide 3, 0.7g ceramide 1, 0.2g schizosaccharomyces cerevisiae fermentation product lysate, 0.6g iceland lichen extract, 0.1g perilla extract, 0.2g polysorbate-80.
The preparation method comprises the following steps:
(1) adding all the raw materials in the phase A into an oil phase pot, stirring and heating to 75 ℃ until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) adding all the raw materials in the phase B into a water phase pot, stirring and heating to 80 ℃, uniformly mixing to form a phase B mixture, and keeping the temperature for later use;
(3) pumping the phase A mixture obtained in the step (1) into an emulsifying pot, adding the phase B mixture obtained in the step (2), emulsifying and homogenizing at 70 ℃ for 12 minutes, and uniformly stirring to form a phase A and phase B mixture; cooling while degassing, cooling to 45 ℃, adding all the raw materials of the phase C, and uniformly stirring; cooling to 35 deg.C to obtain the final product.
Comparative example 1
The only difference between this comparative example and example 6 is that no squalane was added to the starting material and no squalane was added during the preparation.
Comparative example 2
The only difference between this comparative example and example 6 is that no split yeast fermentation lysate was added to the feed and no split yeast fermentation lysate was added during the preparation.
The skin-care soft and moist cleansing milk provided by the invention has better moisturizing and cleansing effects.
Test of moisturizing Effect
In order to evaluate the moisturizing effect of the skin-care soft-moistening cleansing milk, according to the light industry standard QB/T4256-2011 "cosmetic moisturizing efficacy evaluation guideline" of the people's republic of China, a capacitance method skin moisture tester is adopted by the inventor to compare the finished products obtained in the examples 1-3 with the finished products obtained in the comparative examples 1-2.
The principle is as follows: the capacitance method is used for measuring the moisture content of the human skin stratum corneum, and is based on the obvious difference of dielectric constants of water and other substances, the capacitance values of the measured skin are different according to the moisture content of the skin stratum corneum, and the parameters can represent the moisture content of the skin.
And (3) testing environmental conditions:
the temperature is 20-22 ℃, and the humidity is 40-60%.
Test objects: 40 volunteers aged 20-50 years were divided into 4 groups of 10 persons each.
The test method comprises the following steps:
1. firstly, all people are smeared with the same whitening cosmetics, and then the group 1 people only use the skin-regulating soft and moist cleansing cream obtained in the embodiment 6 of the invention before washing hands; the skin-care soft makeup removing milks obtained in comparative examples 1 and 2 were used for makeup removal before washing hands in groups 2 and 3, respectively, and the cleansing milks were used for washing hands in group 4 without using any makeup removing products. The skin on the back of the hand was tested for moisture.
2. And comparing the measured values before and after use, performing statistical analysis on the measured values, including quantity, mean value, standard deviation, minimum value, median value and maximum value, observing the change of the moisture content through the average moisture content before testing and the average moisture content after use, and judging the moisturizing effect of the makeup removing cream.
3. Effect determination criteria:
the effect is achieved, the moisture is improved, and the statistical test shows that the effect is obvious;
no effect, no significant improvement in moisture was obtained.
4. The results of the tests are shown in table 1 below:
TABLE 1 test results
As can be seen from Table 1, the skin moisture of the volunteers is obviously improved and remarkably improved by using the skin-care soft makeup removing cream. The moisturizing effect of the product using the comparative example is far less than that of the skin-care soft makeup removing lotion disclosed by the invention, which shows that the raw materials of the skin-care soft makeup removing lotion disclosed by the invention have a synergistic effect, and the moisturizing effect is obviously improved; the reasonable compatibility of the raw materials gives play to the complementary effect of the raw materials, and can obviously improve the moisturizing effect.
Safety performance testing
Sensitive muscle people can have the reactions of flushing, itching, scalding, stabbing pain and the like on the facial skin by using a common makeup removing product sold in the market; however, the makeup remover product with the effects of protecting the skin barrier and regulating the skin micro-ecology can avoid the above reaction, so that the test selects sensitive muscle personnel as the subject.
Subject: 70 sensitive skin volunteers are selected for testing by adopting a lactic acid stabbing pain test, wherein 35 men and 35 women are divided into 7 groups with the age of 20-49 years, 10 persons, 5 men and 5 women are respectively selected in each group, 1-6 groups respectively use the makeup removing milk of the invention 1-6, and the 7 th group is a negative control group;
lactic acid sting test method: 50 μ l of 10% lactic acid solution was dropped on a single-layer nonwoven fabric having a diameter of 0.8cm, and the nonwoven fabric was applied to the nasolabial sulcus on either side of the subject, and the other side was controlled with distilled water. The investigator asked the subjects for a tingling sensation at 0.5min, 2.5min, 5min, and 8min, respectively, and scored as "4 point method" in Table 2. If the cumulative sum of the stinging sensation on the lactic acid side relative to the distilled water side is more than or equal to 5 points, the patient is judged to be lactic acid stabbed, and the sensitive muscle can be judged. The results of the lactic acid side sting test on volunteers are shown in table 3:
TABLE 2 lactic acid sting rating scale
TABLE 3 volunteer lactic acid stinging test results
The test results in table 3 show that 70 volunteers were all sensitive muscles.
The test method comprises the following steps: the selected area is not more than 50mm2About 0.020g of makeup removing cream of the embodiments 1 to 6 of the invention is coated in the spot tester by a closed spot test method, an external special adhesive tape is pasted on the forearm curve side of each group of volunteers, and the spot tester is removed after 24 hours. After 0.5 hour of removing the makeup removing and breast spot testing device, observing skin reaction after the indentation disappears, respectively observing once again 24 hours and 48 hours after the spot test, and recording the result;
evaluation criteria: subjects were asked by investigators for sensitivity to climate (cold and dry), skin care, detergent, textile and harsh items and were scored as insensitive 0, respectively; 1 is sometimes sensitive; 2 is classified as sensitive. Skin response grading criteria for skin patch test are shown in table 4.
TABLE 4 skin reaction grading Standard for skin Enclosed Patch test
Negative control: deionized water;
the results of the skin patch test are shown in Table 5.
Table 5: skin occlusion patch test results
The test result shows that the grading grades of 70 sensitive muscle subjects 30min, 24h and 48h after the test object spot tester is removed are all 0, and no adverse reaction occurs. The skin-care soft and moist cleansing cream prepared by the composition has good safety, forms a skin-protecting barrier, has the effect of regulating skin micro-ecology, is suitable for sensitive skin, is reasonable in raw material matching, and cannot cause skin allergy.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (10)
1. A skin care soothing composition for a makeup removing lotion, characterized in that the composition is made from the following raw materials: ceramide, amino acid, squalane and a yeast fermentation lysate of the second split yeast.
2. The skin-care soothing composition for the makeup removing cream as claimed in claim 1, wherein the main materials comprise, by weight: 1.1 to 2.6 parts by weight of ceramide, 0.6 to 1.7 parts by weight of amino acid, 0.5 to 1.0 part by weight of squalane and 0.2 to 0.6 part by weight of a split yeast fermentation product lysate.
3. The skin care soothing composition for makeup removing cream according to claim 1, wherein said amino acids comprise arginine and glycine, preferably said amino acids comprise in parts by weight: 0.3-0.9 weight part of arginine and 0.3-0.8 weight part of glycine.
4. A skin soothing composition for a makeup removing lotion according to any of claims 1 to 3 wherein said ceramide comprises ceramide 1, ceramide 3 and ceramide 6.
5. The skin care soothing composition for a makeup removing lotion according to claim 4, wherein said ceramide comprises, in parts by weight: 0.3 to 0.7 part by weight of ceramide 1, 0.3 to 0.7 part by weight of ceramide 3 and 0.5 to 1.2 parts by weight of ceramide 6.
6. The skin-care soft makeup removing lotion prepared from the composition according to any one of claims 1 to 5, which is characterized by comprising main materials and auxiliary materials, wherein the main materials are ceramide, amino acid, squalane and lysate of fermentation products of saccharomyces bifidus, and the auxiliary materials comprise glycerol cocoate, caprylic/capric triglyceride, iceland lichen extract, arginine and glycine.
7. The skin-care soft makeup removing lotion according to claim 6, which is prepared from the following raw materials in parts by weight:
phase A: 3.0-5.0 parts of PEG-7 glyceryl cocoate, 4.0-8.0 parts of caprylic/capric triglyceride, 0.1-0.2 part of isohexadecane, 0.1-0.2 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer and 0.5-1.0 part of squalane;
phase B: 80.0-88.0 parts of water, 0.2-0.3 part of glycerol, 0.3-0.9 part of arginine and 0.3-0.8 part of glycine;
and C phase: 0.5-1.2 parts of ceramide 6, 0.3-0.7 part of ceramide 3, 0.3-0.7 part of ceramide 1, 0.2-0.6 part of schizosaccharomyces cerevisiae fermentation product lysate, 0.4-0.6 part of iceland lichen extract, 0.1-0.3 part of asiatic pennywort leaf extract and 0.1-0.2 part of polysorbate-80.
8. The skin-care soft makeup removing lotion according to claim 6, which is prepared from the following raw materials in parts by weight:
phase A: 3.0-5.0 parts of PEG-7 glyceryl cocoate, 4.0-8.0 parts of caprylic/capric triglyceride and 0.5-1.0 part of squalane;
phase B: 80.0-88.0 parts of water, 0.3-0.9 part of arginine and 0.3-0.8 part of glycine;
and C phase: 0.5-1.2 parts of ceramide 6, 0.3-0.7 part of ceramide 3, 0.3-0.7 part of ceramide 1, 0.2-0.6 part of schizosaccharomyces cerevisiae fermentation product lysate, 0.4-0.6 part of iceland lichen extract, 0.1-0.3 part of perilla extract and 0.1-0.2 part of polysorbate-80.
9. Method for preparing a skin-soothing make-up remover according to claim 7 or 8, characterized in that it comprises the following steps:
(1) adding all the raw materials in the phase A into an oil phase pot, stirring and heating until all the raw materials in the phase A are completely dissolved until no particles exist, uniformly mixing to form a phase A mixture, and keeping the temperature for later use;
(2) adding all the raw materials in the phase B into a water phase pot, stirring and heating, uniformly mixing to form a phase B mixture, and keeping the temperature for later use;
(3) pumping the phase A mixture obtained in the step (1) into an emulsifying pot, adding the phase B mixture obtained in the step (2), emulsifying and homogenizing for 8-12 minutes, and uniformly stirring to form a phase A and phase B mixture; cooling while degassing, cooling to 40-45 deg.C, adding all the raw materials of phase C, and stirring; cooling to 25-35 deg.C to obtain the final product.
10. The method for preparing the skin-care soft makeup remover according to claim 9, wherein in the step (1), all the raw materials in the phase A are added into an oil phase pot, stirred and heated to 75-80 ℃ until all the raw materials in the phase A are completely dissolved to be free of particles, in the step (2), all the raw materials in the phase B are added into an aqueous phase pot, stirred and heated to 70-80 ℃, and in the step (3), the emulsifying and homogenizing temperature is 65-70 ℃.
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