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CN102084869A - Compound hydrogen peroxide disinfection solution - Google Patents

Compound hydrogen peroxide disinfection solution Download PDF

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Publication number
CN102084869A
CN102084869A CN2011100210932A CN201110021093A CN102084869A CN 102084869 A CN102084869 A CN 102084869A CN 2011100210932 A CN2011100210932 A CN 2011100210932A CN 201110021093 A CN201110021093 A CN 201110021093A CN 102084869 A CN102084869 A CN 102084869A
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hydrogen peroxide
compound
disinfection
dimethyl ammonium
disinfection solution
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潘运平
王佩佩
姚勤光
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Abstract

The invention relates to compound hydrogen peroxide disinfection solution and a preparation and a use thereof, and a disinfectant is the disinfection solution prepared by hydrogen peroxide (1), dioctyl/didecyl dimethyl ammonium chloride (2), glutaric acid peroxide (3), phytic acid (4), fatty alcohol polyoxyethylene ether (5) and deionized water (6). The compound hydrogen peroxide disinfection solution is characterized in that the content of hydrogen peroxide in the compound hydrogen peroxide solution is 8.5-12.5%, and the content of the dioctyl/didecyl dimethyl ammonium chloride is 0.5-10.5%. The compound peroxide disinfection solution provided by the invention is applicable to surface disinfection of ordinary objects, environmental disinfection of spore pollutants and large breeding farms, and disinfection of livestock and poultry mews, appliances and the like. The compound hydrogen peroxide disinfection solution particularly has a significant role in killing various infectious diseases happened in recent years, such as hepatitis B virus, SARS (severe acute respiratory syndrome), avian influenza virus, influenza A virus subtype H1N1, hand-foot-and-mouth disease virus and the like.

Description

A kind of compound disinfectant with hydrogen peroxide liquid
Technical field
The present invention relates to a kind of broad-spectrum high efficacy type disinfection sanitizer, relate to a kind of hydrogen peroxide, two eight/ten alkyl-dimethyl ammonium chlorides, glutaric acid, phytic acid, fatty alcohol-polyoxyethylene ether and formulated compound hydrogen peroxide of deionized water of containing specifically.
Background technology
The chemical formula of hydrogen peroxide: HO-OH
Hydrogen peroxide and glutaric acid composition:
Figure BSA00000421548000011
The chemical formula of two Ba ten alkyl-dimethyl ammonium chlorides:
Figure BSA00000421548000012
The chemical formula of phytic acid:
This compound disinfectant with hydrogen peroxide agent has comprised hydrogen peroxide, two eight/ten alkyl-dimethyl ammonium chlorides, glutaric acid, phytic acid, fatty alcohol-polyoxyethylene ether and deionized water.Because two eight/ten alkyl-dimethyl ammonium chlorides have very strong affinity to thalline, by absorption, dissolving thalline endochylema film, reduce the surface tension of pathogene, increase the permeability of cell membrane, cause the leakage of important enzyme and nutriment, water infiltrates thalline makes its damaged or dissolving, and then the active group of oxidation mycoprotein, and combine with amino acid in the albumen and cause sex change and suppress the metabolic enzyme system of thalline, impel thalline disintegration death.Glutaric acid and hydrogen peroxide have synergy, can produce the chain reaction of free radical, make it have stronger sterilizing ability.Hydroxyl in phytic acid and the fatty alcohol-polyoxyethylene ether molecule can form hydrogen bond with hydrogen peroxide molecule, has increased stability of peroxide, makes it be difficult for decomposing, and has reduced its corrosiveness to metallic article widely.
Summary of the invention
The novel technical problem that solves of the present invention is a kind of compound disinfectant with hydrogen peroxide liquid, the characteristics of this product maximum are that the residue that decomposes has only water and oxygen, health there is not any injury, little to equipment corrosion, fundamentally broken the tradition sterilization theory of " sterilization just has residual ".This product bactericidal action time is short, and working concentration is low, thereby has reduced use cost.Show according to the literature, concentration is 0.25% compound hydrogenperoxide steam generator, it is 99.99% that effect 15min kills staphylococcus aureus (ATCC6538 strain), and this compound hydrogenperoxide steam generator is being diluted under 0.02% the concentration, and only need act on 10min is 100% to the killing rate of staphylococcus aureus (ATCC6538 strain).Diluted concentration according to bibliographical information has improved 12.5 times.Added fatty alcohol-polyoxyethylene ether in this product simultaneously, the hydroxyl in its molecule can form hydrogen bond with hydrogen peroxide molecule, has increased stability of peroxide.By quickening experiment, prove this product at (1) 54 ℃, under 14 days conditions, rate of descent is 3.1%, (2) 37 ℃,, under 3 months conditions, rate of descent is 7.3%, above data show that this product term of validity is 2 years.
The technical scheme that the present invention takes is: by hydrogen peroxide, two eight/ten alkyl-dimethyl ammonium chlorides, glutaric acid, and phytic acid, fatty alcohol-polyoxyethylene ether and deionized water are formulated.This experimental formula is formed: contain peroxidating 283.3~416.7g among every 1000ml, two eight/ten alkyl-dimethyl ammonium chlorides, 7.1~150g, glutaric acid: 20.0~30.0g, phytic acid: 10.0~20.0g, fatty alcohol-polyoxyethylene ether: 40.0~70.0g.
Description of drawings:
Fig. 1. compound disinfectant with hydrogen peroxide liquid production technology sketch.
Embodiment
Implement 1: this compound hydrogen peroxide mainly comprises hydrogen peroxide, two eight/ten alkyl-dimethyl ammonium chlorides, glutaric acid, phytic acid, fatty alcohol-polyoxyethylene ether and deionized water.The described compound disinfectant with hydrogen peroxide of wherein every 1000ml liquid contains hydrogen peroxide 283.3g, two eight/ten alkyl-dimethyl ammonium chloride 7.1g, and glutaric acid 10.2g, fatty alcohol-polyoxyethylene ether 40g, phytic acid 1.9g, surplus is a deionized water.
Implement 2: this compound hydrogen peroxide mainly comprises hydrogen peroxide, two eight/ten alkyl-dimethyl ammonium chlorides, glutaric acid, phytic acid, fatty alcohol-polyoxyethylene ether and deionized water.The described compound disinfectant with hydrogen peroxide of wherein every 1000ml liquid contains hydrogen peroxide 323.3g, two eight/ten alkyl-dimethyl ammonium chloride 50g, and glutaric acid 15.3g, fatty alcohol-polyoxyethylene ether 47g, phytic acid 3.8g, surplus is a deionized water.
Implement 3: this compound hydrogen peroxide mainly comprises hydrogen peroxide, two eight/ten alkyl-dimethyl ammonium chlorides, glutaric acid, phytic acid, fatty alcohol-polyoxyethylene ether and deionized water.The described compound disinfectant with hydrogen peroxide of wherein every 1000ml liquid contains hydrogen peroxide 350.0g, two eight/ten alkyl-dimethyl ammonium chloride 78.6g, and glutaric acid 20.4g, fatty alcohol-polyoxyethylene ether 55g, phytic acid 9.6g, surplus is a deionized water.
Implement 4: this compound hydrogen peroxide mainly comprises hydrogen peroxide, two 80 alkyl-dimethyl ammonium chlorides, glutaric acid, phytic acid, fatty alcohol-polyoxyethylene ether and deionized water.The described compound disinfectant with hydrogen peroxide of wherein every 1000ml liquid contains hydrogen peroxide 390.0g, two eight/ten alkyl-dimethyl ammonium chloride 107.1g, and glutaric acid 25.5g, fatty alcohol-polyoxyethylene ether 65g, phytic acid 13.5g, surplus is a deionized water.
Implement 5: this compound hydrogen peroxide mainly comprises hydrogen peroxide, two 80 alkyl-dimethyl ammonium chlorides, glutaric acid, phytic acid, fatty alcohol-polyoxyethylene ether and deionized water.The described compound disinfectant with hydrogen peroxide of wherein every 1000ml liquid contains hydrogen peroxide 416.7g, two eight/ten alkyl-dimethyl ammonium chloride 150g, and glutaric acid 30.6g, fatty alcohol-polyoxyethylene ether 70g, phytic acid 19.2g, surplus is a deionized water.
This compound disinfectant with hydrogen peroxide agent sees the following form through Jiangsu Prov. Disease Preventing and Controlling Center's check conclusion:
(1) agent of compound disinfectant with hydrogen peroxide is to the killing effect of experimental bacteria
Figure BSA00000421548000041
Annotate: negative control is asepsis growth.
Conclusion: sample dilution effect in 1: 500 5min kills logarithm value>5.00 to staphylococcus aureus, and 1: 1000 diluting effect 10min of sample is to logarithm value>5.00 of staphylococcus aureus.The suggestion working concentration is 1: 500 dilution, and be 10~20min action time.
(2) agent of compound disinfectant with hydrogen peroxide is to the killing effect of experimental bacteria
Figure BSA00000421548000042
Annotate: negative control is asepsis growth.
Conclusion: sample stoste effect 30min, 60min, 90min is to dying hay bacillus on the cloth sheet
The logarithm value of on average killing of black mutation gemma is respectively 2.95 (2.84~3.03), 5.45 (5.23~6.20), 6.23 (6.10~6.34).Suggestion is used stoste effect 60min to the sterilization of bacillus subtilis black variety gemma.
1. this compound disinfectant with hydrogen peroxide agent, diluted concentration 1: 500 times the effect 10min, to Escherichia coli, staphylococcus aureus, Pasteurella, Candida albicans, killing rate be 100%.
2. the disinfectant of this compound hydrogen peroxide, stoste can be killed gemma and gemma pollutant, all kinds of infectious diseases such as hepatitis B especially to being taken place in recent years, SURS, avian influenza virus, first type HN1 influenza virus, hand-foot-and-mouth disease poison etc. all has significant killing effect.

Claims (2)

1. compound disinfectant with hydrogen peroxide liquid, it is characterized in that (1) hydrogen peroxide, (2) two eight/ten alkyl-dimethyl ammonium chlorides, (3) glutaric acid, (4) phytic acid, (5) fatty alcohol-polyoxyethylene ether, the formulated thimerosal of (6) deionized water contains hydrogen peroxide 283.3~416.7g in every liter, two eight/ten alkyl-dimethyl ammonium chlorides, 7.1~150g, glutaric acid: 10.2~30.6g, phytic acid: 1.9~19.2.g, fatty alcohol-polyoxyethylene ether: 40.0~70.0g.
2. according to claim 1, it is characterized in that content of hydrogen peroxide is 8.5~12.5% in the compound hydrogenperoxide steam generator, two eight/ten alkyl-dimethyl ammonium chlorides 0.5~10.5%, glutaric acid 1.5~3.0%, phytic acid 0.1~1%.
CN2011100210932A 2011-01-19 2011-01-19 Compound hydrogen peroxide disinfection solution Pending CN102084869A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102273488A (en) * 2011-06-22 2011-12-14 李翰实 Nascent oxygen high speed specific bactericidal disinfectant
CN107072216A (en) * 2014-09-09 2017-08-18 龙沙股份有限公司 Antiseptic composition containing quaternary ammonium compound
CN107593764A (en) * 2017-10-13 2018-01-19 中国民用航空局民用航空医学中心 A kind of thimerosal and application thereof
CN110558307A (en) * 2019-09-06 2019-12-13 无锡市思忆真研科技有限公司 Remains deodorizing disinfectant
JP2020524201A (en) * 2017-06-15 2020-08-13 ディコン7 システムズ エルエルシーDecon7 Systems,Llc Purification formulation
CN111567524A (en) * 2020-04-29 2020-08-25 广西夏阳环保科技有限公司 Efficient composite peroxide disinfectant and preparation method thereof
CN111700910A (en) * 2019-08-26 2020-09-25 武汉康德庆生物科技有限公司 Cleaning disinfectant for preventing human from infecting animal germs

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1552211A (en) * 2003-05-27 2004-12-08 拉萨绿能科技实业有限公司 Antiseptics for improving hydrogen peroxide sterilizing activity and preparing process thereof
CN1709061A (en) * 2005-06-30 2005-12-21 兰州益生化工有限公司 Compound peroxide acid sterilizing agent and its processing method
CN101053330A (en) * 2006-04-12 2007-10-17 拉萨绿能科技实业有限公司 Disinfectant for improving hydrogen peroxide bactericidal activity

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1552211A (en) * 2003-05-27 2004-12-08 拉萨绿能科技实业有限公司 Antiseptics for improving hydrogen peroxide sterilizing activity and preparing process thereof
CN1709061A (en) * 2005-06-30 2005-12-21 兰州益生化工有限公司 Compound peroxide acid sterilizing agent and its processing method
CN101053330A (en) * 2006-04-12 2007-10-17 拉萨绿能科技实业有限公司 Disinfectant for improving hydrogen peroxide bactericidal activity

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102273488A (en) * 2011-06-22 2011-12-14 李翰实 Nascent oxygen high speed specific bactericidal disinfectant
CN107072216A (en) * 2014-09-09 2017-08-18 龙沙股份有限公司 Antiseptic composition containing quaternary ammonium compound
JP2020524201A (en) * 2017-06-15 2020-08-13 ディコン7 システムズ エルエルシーDecon7 Systems,Llc Purification formulation
JP7102008B2 (en) 2017-06-15 2022-07-19 ディコン7 システムズ インク Purification product
CN107593764A (en) * 2017-10-13 2018-01-19 中国民用航空局民用航空医学中心 A kind of thimerosal and application thereof
CN111700910A (en) * 2019-08-26 2020-09-25 武汉康德庆生物科技有限公司 Cleaning disinfectant for preventing human from infecting animal germs
CN110558307A (en) * 2019-09-06 2019-12-13 无锡市思忆真研科技有限公司 Remains deodorizing disinfectant
CN111567524A (en) * 2020-04-29 2020-08-25 广西夏阳环保科技有限公司 Efficient composite peroxide disinfectant and preparation method thereof

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Assignee: Jiangsu Tian Yijian disinfectant company limited

Assignor: Pan Yunping|Wang Peipei|Yao Qinguang

Contract record no.: 2012320000827

Denomination of invention: Compound hydrogen peroxide disinfection solution

License type: Exclusive License

Open date: 20110608

Record date: 20120626

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Application publication date: 20110608