CN101757591B - Traditional Chinese medicine composition for treating chronic colitis and protitis - Google Patents
Traditional Chinese medicine composition for treating chronic colitis and protitis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating chronic colitis and protitis, which comprises the following components in parts by weight: 6-40 parts of dried ginger, 6-30 parts of ossa draconis, 10-40 parts of umbellate pore fungus, 10-40 parts of fructus chebulae, 8-42 parts of myristica fragrans, 6-30 parts of prepared liquorice, 10-48 parts of red halloysite, 6-40 parts of dogwood, 6-38 parts of szechwan Chinaberry fruit, 6-45 parts of rhizoma alismatis, 3-15 parts of monkshood, 10-40 parts of yam, 6-40 parts of costustoot, 3-15 parts of goldthread, 8-25 parts of dangshen, 3-30 parts of hairyvein agrimony, 3-30 parts of tenodera aridifolia stoll and 3-30 parts of dried alum. Proved by clinical application for many years, the traditional Chinese medicine composition has the functions of tonifying the spleen and the kidney and regulating the intestines and stomach, achieves the purpose of treating both principal and secondary aspect of diseases, can not generate any toxic or side effect during the taking, overcomes the defects of many medicaments for treating the chronic colitis and protitis, solves the problem that the traditional western medicines cure the symptoms, but does not cure the cause.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of chronic colitis, proctitis.
Background technology
Colitis belongs to that the traditional Chinese medical science " is had loose bowels ", " diarrhoea ", be clinical frequently-occurring disease, commonly encountered diseases.Cause that the diarrheal reason is a lot, mainly be weakness of the spleen and stomach, in the damp and hot stagnant intestinal, QI and blood is because of the conduction block anergy, damp and hot poison is smoked bright and is injured due to the QI and blood, it is painful abdomen to occur, and tenesmus or half congealed watery stool also bloody purulent stool can occur, the defecation frequency showed increased, heavy person has loose bowels and does not wait with several to ten several, becomes intractable diarrhea, does not heal for a long time.
Treatment diarrheal Western medicine often has the defective of curing the symptoms, not the disease.Because of Western medicine is chemical synthetic drug mostly, both eliminated harmful bacterium after taking medicine, also murdered the intestinal beneficial bacterium group, Drug resistance also appears easily.So on the basis of original medication, do not have the effect that antiinflammatory relieves the pain,, make it obstinate so delay the state of an illness.
CN1785420A discloses a kind of medicine for external use of the treatment chronic enteritis of being made up of Chinese medicines such as Radix Codonopsis, Rhizoma Dioscoreae, Radix Glycyrrhizae, Rhizoma Coptidis, the Radix Aucklandiae, Rhizoma Zingiberis, Radix Aconiti Lateralis Preparata, Semen Myristicaes; CN1919330A discloses a kind of Chinese medicine and method for making thereof of the treatment chronic colitis of being made up of Chinese medicines such as Radix Codonopsis, Radix Aconiti Lateralis Preparata, Radix Glycyrrhizae, Rhizoma Coptidis, the Radix Aucklandiae, Rhizoma Zingiberis Preparatum, Semen Myristicae, Herba Agrimoniae, Rhizoma Dioscoreae, Fructus Chebulaes, and it needs to decoct, and preparation method is loaded down with trivial details; In addition, the existing people in non-patent literature aspect provides the Therapeutic Method of damp-heat accumulation type, due to weakness of spleen and stomach, disharmony between the liver and spleen type, yang deficiency of spleen and stomache and qi stagnation and blood stasis type colitis, and (shallow view chronic non-specific ulcerative colitis card is controlled, the Heilungkiang Chinese medicine, 2003 the 2nd phases, 3-4 page or leaf); The somebody discloses a kind of Chinese medicine (powdered medicine ' Jiechangning ' treatment ulcerative colitis 90 examples, Xinjiang Chinese medicine, the 21st the 2nd phase of volume, the 20th page) of the treatment ulcerative colitis of being made up of Chinese medicines such as Radix Codonopsis, Rhizoma Coptidis, the Radix Aucklandiae, Semen Myristicae, Halloysitum Rubrum, Fructus Chebulae, Radix Glycyrrhizaes.But the method for traditional Chinese medicine or Chinese patent drugs for treatment colitis often can mitigation symptoms, and can not remove basic, the colitis that only one or both exopathogen is caused that has is effective, and processing technology is comparatively loaded down with trivial details, and cost is higher, and the patient takes or use comparatively inconvenience.
Summary of the invention
In order to overcome the deficiencies in the prior art, the object of the present invention is to provide a kind of Chinese medicine composition, not only with low cost, processing technology is simple, taking convenience, but also the constraint of having broken traditional therapy, method with the common benefit of removing heat by catharsis, the merit that building digs up the roots consolidates, form is taken the course of its own, and the compatibility of drugs the monarch and his subjects are clearly demarcated, keen-witted and capable reasonable, be applicable to the colitis that various exopathogen cause, be easy to promote, benefit the people.
In order to achieve the above object, the invention provides a kind of Chinese medicine composition for the treatment of chronic colitis, proctitis, comprise the raw material of following weight portion: Rhizoma Zingiberis 6-40 part, Os Draconis 6-30 part, Polyporus 10-40 part, Fructus Chebulae 10-40 part, Semen Myristicae 8-42 part, Radix Glycyrrhizae Preparata 6-30 part, Halloysitum Rubrum 10-48 part, Fructus Corni 6-40 part, Fructus Toosendan 6-38 part, Rhizoma Alismatis 6-45 part, Radix Aconiti Lateralis Preparata 3-15 part, Rhizoma Dioscoreae 10-40 part, Radix Aucklandiae 6-40 part, Rhizoma Coptidis 3-15 part, Radix Codonopsis 8-25 part, Herba Agrimoniae 3-30 part, Ootheca Mantidis 3-30 part, dried Alumen 3-30 part.
Described Chinese medicine composition preferably includes the raw material of following weight portion: 30 parts of Rhizoma Zingiberiss, 10 parts of Os Draconis, 15 parts of Polyporus, 30 parts of Fructus Chebulaes, 15 parts of Semen Myristicaes, 20 parts of Radix Glycyrrhizae Preparatas, 20 parts of Halloysitum Rubrums, 20 parts of Fructus Corni, 20 parts of Fructus Toosendans, 15 parts of Rhizoma Alismatis, 10 parts of Radix Aconiti Lateralis Preparatas, 20 parts of Rhizoma Dioscoreaes, 20 parts of the Radix Aucklandiae, 10 parts of Rhizoma Coptidis, 20 parts of Radix Codonopsis, 15 parts of Herba Agrimoniaes, 15 parts of Ootheca Mantidiss, 15 parts of dried Alumens.
The inventor learns the elite of ancestors' several generations medical science, and for some chronic diseases, in the practice of several generations' long periods of treatment, through screening for many years, checking has accumulated certain experience repeatedly.Particularly to chronic diarrhea (colitis, proctitis), sum up its main pathological characteristic, on this basis, with strengthening spleen, tonifying kidney, warming spleen and stomach for dispelling cold, Guyang promote blood circulation, astringent therapy holds back and takes off, lead and damp and hotly down walk to ooze and diuresis is the Chinese medicine composition of the present invention of the main rule of treatment, on clinical practice, obtained comparatively satisfied and effect reliably.
The present invention is astringent or styptic treatment for spontaneous sweating with tonneau urine, convergence, consolidate beneficial intestinal, and spleen reinforcing is main.Adopt Polyporus, Fructus Toosendan and Rhizoma Alismatis diuresis, logical large intestine, can lead and walk to ooze under damp and hot; Rhizoma Zingiberis, Radix Aconiti Lateralis Preparata warming spleen and stomach for dispelling cold, Guyang are promoted blood circulation; Os Draconis are returned large intestine, tranquilizing mind, suppressing the hyperactive liver and subsiding YANG; Halloysitum Rubrum relieving diarrhea with astringent, astringent therapy are held back skin ulcer, control the chronic diarrhea chronic dysentery, have blood in stool; Fructus Chebulae, Rhizoma Dioscoreae spleen reinforcing are controlled diarrhea of deficiency type and are gone into large intestine; The Radix Glycyrrhizae Preparata invigorating the spleen and replenishing QI, slow in pain relieving, return the taste warp; Semen Myristicae is gone into heart spleen large intestine channel, warming middle-JIAO astringing intestine to stop diarrhea, and promote qi circulation digestion promoting is controlled diarrhea of deficiency type cold-dysentery, epigastric pain; The Fructus Corni kidney-supplementing liver-boosting, convergence is taken off admittedly; Radix Aucklandiae promoting the circulation of QI to relieve pain, intestinal stasis relieving in the accent; The Rhizoma Coptidis clearing away heat-fire, the dampness detoxifcation; The Radix Codonopsis strengthening the spleen and tonifying the lung; Herba Agrimoniae is only held back hemostasis, the removing food stagnancy dysentery relieving; Ootheca Mantidis controlling nocturnal emission with astringent drugs reducing urination, reinforcing the kidney and supporting YANG; Dried Alumen dampness, the antidiarrheal hemostasis.
Chinese medicine composition object space of the present invention is separated: with Polyporus, Rhizoma Alismatis, Fructus Toosendan, Rhizoma Dioscoreae, Semen Myristicae is monarch, at the logical large intestine of diuresis, lead the while warming middle-JIAO spleen reinforcing of walking to ooze under damp and hot, relieving diarrhea with astringent, wherein, with the power that Polyporus, Rhizoma Alismatis, Fructus Toosendan close medicine, drive away exopathogen, unobstructed intestinal, with the auxilliary mutually merit reinforcing Guyuan of Rhizoma Dioscoreae, Semen Myristicae, gas in the temperature compensation, residence leads in benefit, posts and mends in logical, the two complements each other, the well-founded of building together; With Halloysitum Rubrum, dried Alumen, Ootheca Mantidis, Fructus Chebulae, Os Draconis is minister, relieving diarrhea with astringents, and through sick institute, with the energy of specializing in, the power that supplies after continuous.
The used crude drug of the present invention all can be bought from common pharmacy and obtain, and its specification meets national medical standard.
This pharmaceutical composition can conventional drug formulation process be prepared into any common peroral dosage form, for example tablet, capsule, granule, powder, pill, suspensoid or oral liquid etc., preferred capsule, tablet, granule, powder or pill, more preferably capsule.
The preparation method of Chinese medicine composition of the present invention is: above each composition is taken by weighing respectively according to the part by weight that limits above, fully mix then, with the pulverizer grinding and sieving, be ground into 120 order fine flours altogether, make finished product through preparations shaping technology.For example fine flour can be made powder by common process or incapsulate, or the conventional solvent of adding (as distilled water) carries out conventional decoction extraction in fine flour, extracting solution is condensed into fluid extract, mix with the commonly used adjuvant of materia medica or excipient (for example beta-schardinger dextrin-etc.) again, can further adopt common process to be processed into granule, tablet, pill etc.In the preferred embodiment of the present invention, adopt artificial or machinery incapsulates, every capsules content of dispersion 0.7 gram.Technology is simple, and is cheap for manufacturing cost.
Instructions of taking: during clinical practice, according to the disease weight, age size, or body constitution difference are taken the circumstances into consideration plus-minus.As guidance: capsule, each oral 3.5-4.9 gram of being grown up, days 3 times, half an hour ante cibum or one hour be for oral administration all can.
Through clinical practice for many years, use this medicine not only spleen reinforcing but also the kidney invigorating, the effect of adjusting the intestines and stomach is arranged again, reach treating both the principal and secondary aspects of a disease, general 3-5 days take effect, and take recovery from illness about month.In the middle of taking, do not produce any toxic side effects, remedied the deficiency of many treatment chronic colitis proctitis medicines, also overcome the defective that Western medicine is in the past cured the symptoms, not the disease, really become the specially good effect prescription of treatment chronic colitis and proctitis.
The specific embodiment
The invention will be further described below in conjunction with embodiment, it should be understood that these embodiment only are used for the purpose of illustration, never limit protection scope of the present invention.
[embodiment 1]
Take by weighing each raw material by following weight: Rhizoma Zingiberis 30 grams, Os Draconis 10 grams, Polyporus 15 grams, Fructus Chebulae's 30 grams, Semen Myristicae 15 grams, Radix Glycyrrhizae Preparata 20 grams, Halloysitum Rubrum 20 grams, Fructus Corni 20 grams, Fructus Toosendan 20 grams, Rhizoma Alismatis 15 grams, Radix Aconiti Lateralis Preparata 10 grams, Rhizoma Dioscoreae 20 grams, the Radix Aucklandiae 20 grams, Rhizoma Coptidis 10 grams, Radix Codonopsis 20 grams, Herba Agrimoniae 15 grams, Ootheca Mantidis 15 grams, dried Alumen 15 grams;
Above each composition is fully mixed, with the pulverizer grinding and sieving, be ground into 120 order fine flours altogether, artificial or machinery incapsulates.
[embodiment 2]
Take by weighing each raw material by following weight: Rhizoma Zingiberis 6 grams, Os Draconis 6 grams, Polyporus 10 grams, Fructus Chebulae's 10 grams, Semen Myristicae 8 grams, Radix Glycyrrhizae Preparata 6 grams, Halloysitum Rubrum 10 grams, Fructus Corni 6 grams, Fructus Toosendan 6 grams, Rhizoma Alismatis 6 grams, Radix Aconiti Lateralis Preparata 3 grams, Rhizoma Dioscoreae 10 grams, the Radix Aucklandiae 6 grams, Rhizoma Coptidis 3 grams, Radix Codonopsis 8 grams, Herba Agrimoniae 3 grams, Ootheca Mantidis 3 grams, dried Alumen 3 grams;
Above each composition is fully mixed, with the pulverizer grinding and sieving, being ground into 120 order fine flours altogether is positioned in the extraction pot, add distilled water (amount of water is 2-3 a times of medical material weight) and fully soaked medical material about 0.5 hour, add again distilled water (make the total amount that adds water for twice be medical material weight 4-5 doubly) decoct, the time is about 1 hour; Decoct the back filtered while hot, filtrate for later use, medicinal residues add distilled water and decoct twice again, and each amount of water is about 2 times of medical material weight, and the time is about 0.5 hour; Merge 3 times filtrate, be condensed into fluid extract, medicinal residues discard; After getting fluid extract and being mixed and made into soft material by (1: 1) concentration and adjuvant adjuvants commonly used such as (for example) beta-schardinger dextrin-s, last granulation machine is granulated, and granule is made the semi-finished product granule through flowing steam or airpillow-dry, makes the single-size agent through pelletizing machine.
[embodiment 3]
Take by weighing each raw material by following weight: Rhizoma Zingiberis 40 grams, Os Draconis 30 grams, Polyporus 40 grams, Fructus Chebulae's 40 grams, Semen Myristicae 42 grams, Radix Glycyrrhizae Preparata 30 grams, Halloysitum Rubrum 48 grams, Fructus Corni 40 grams, Fructus Toosendan 38 grams, Rhizoma Alismatis 45 grams, Radix Aconiti Lateralis Preparata 15 grams, Rhizoma Dioscoreae 40 grams, the Radix Aucklandiae 40 grams, Rhizoma Coptidis 15 grams, Radix Codonopsis 25 grams, Herba Agrimoniae 30 grams, Ootheca Mantidis 30 grams, dried Alumen 30 grams;
Above each composition is fully mixed, and the pulverizer grinding and sieving is ground 120 order fine flours altogether, after making granule as described in the embodiment 2, dry, compacting in blocks tablet.
[test example 1]
One, case data
As follows especially exemplified by several routine patients:
1. Gao Fengzhi, woman, 45 years old, Baoding Xu Zhuan people from village.The main suit, once accidental suffering from cold produced diarrhea and vomiting from 1996, rare watery stool symptom, symptom takes a turn for the better through treatment back, locality, stop to vomit, but times of defecation is still more than 5-7 time, and how with abdominal distention, belch symptom.Affiliated Hospital of Hebei University is diagnosed as chronic colitis through the Baoding, and treatment is not healed so far year in year out.Then award this combination treatment, each 5, every day 3 times, taking medicine before meal.After taking 5 days, stool reduces to every day 3-4 time, and the abdominal distention symptom obviously alleviates, and symptom is fully recovered after controlling 35 days.
2. yellow color living, man, 48 years old, Baoding Xu Zhuan people from village.On March 15th, 2006 came me to go to a doctor, main suit's symptom: long-term diarrhea, flatulence, just before abdomen painful.Through how tame hospital therapy, be diagnosed as chronic colitis.Through examining, abdominal part does not have presses painful, stringy pulse, tongue fur light white.Through using above-mentioned composition of medicine, month surplus and heal.
3. open precious qin, woman, 52 years old, Wangdu County Yang Jia people from village.Long-term diarrhea, is met cold reception wind, sx at every day 4-5 time.Come me to go to a doctor on August 2nd, 2006, after the 10 days symptoms of taking medicine are eliminated, do not follow the doctor's advice withdrawal.2006 the end of the year symptomatic recurrence, satisfy my the institute's further consultation of coming on February 14th, 2007, through doctor's advice, after symptom takes a turn for the better, continue medication to recovery from illness, take a period of time again to consolidate curative effect, take altogether and do not recur so far after this compositions in 40 days.
4. Chen Ming ferrum, man, 45 years old, retail department, perambulator big world, China street, Wangdu County.Patient's readme, since 2004, always the painful diarrhoea of abdomen, just before stomachache, pain relief behind the defecation, through Tangxian County institute of traditional Chinese medicine, the Wangdu County hospitalize commentaries on classics of not getting better in 2 months.Come my institute's diagnosis and treatment on October 16th, 2004.Symptom: yellowish fur, slippery and rapid pulse, abdominal tenderness is the tenesmus sense every day just 4-6 time, is diagnosed as chronic colitis then, heals after took this composition of medicine 35 days, so far not recurrence.
5. poplar Xiushan Mountain, man, 60 years old, Wangdu County hospital radiological department doctor.Suffered from colitis 8 years, and came my institute's diagnosis and treatment on April 23rd, 2005, symptom is: diarrhoea abdominal distention, dysphoria with smothery sensation is thirsty, stool yellowish-brown, yellow urine, white and greasy fur.Take this compositions January and heal.
6. Gao Ping, the woman, 50 years old, Radix Perillae people from village in Shunping County came me to go to a doctor on June 15th, 2007.Diarrhoea 7 years is suffered from my private prosecution, and is just rare, can not be shaped, with the tenesmus sense, can not sitting, and then the anus thorn is overworked in sitting.Through looking into, yellowish fur, soft and rapid pulse, according to above disease, this disease belongs to damp and hot heresy invades and the intestines and stomach, the development of evil in febrile disease is not normal, damp invasion of lower energizer, so burning sensation of the anus is diagnosed as chronic proctitis then, after take this compositions, January and healing.
7. poplar triumph, the man, 46 years old, river, Baoding people from city suffered from surplus the colitis ten year, is eating and drinking without temperance through examining, due to spleen and stomach function is impaired.Taking this compositions fully recovered after 20 days.
8. Tian Lizeng, the man, 42 years old, country estate, Wangdu County people from village suffered from colitis, take norfloxacin and sulfasalazine sheet after symptom take a turn for the better, recur after the drug withdrawal.Came my institute's diagnosis and treatment on March 22nd, 2008.Disease is seen, yellowish fur, thready and weak pulse.Take the recovery from illness in 25 days of this compositions, so far not recurrence.
Two, Therapeutic Method
Take the capsule of the embodiment of the invention 1 preparation, obey the 3.5-4.9 gram at every turn, day 3 times, take orally half an hour ante cibum or one hour and all can.
Four, therapeutic outcome
1. criterion of therapeutical effect: after taking this Chinese medicine composition, the state of an illness alleviates or symptom is eliminated to be and taken effect; After taking this Chinese medicine composition, symptom is eliminated fully, and the patient returns to normal condition, is recovery from illness.
2. result: in the clinical practice in more than 40 years, through treat thousands of examples down of patient with the present invention, because of not following the doctor's advice, or other reasons is failed to take medicine on time and is caused DeGrain or invalid account for 3%, all the other are all cured, and total effective rate reaches 95%, and cure rate is more than 90%.Really become the specially good effect prescription of treatment chronic colitis and proctitis.
Claims (7)
1. a Chinese medicine composition for the treatment of chronic colitis, proctitis is made by following materials of weight proportions: Rhizoma Zingiberis 6-40 part, Os Draconis 6-30 part, Polyporus 10-40 part, Fructus Chebulae 10-40 part, Semen Myristicae 8-42 part, Radix Glycyrrhizae Preparata 6-30 part, Halloysitum Rubrum 10-48 part, Fructus Corni 6-40 part, Fructus Toosendan 6-38 part, Rhizoma Alismatis 6-45 part, Radix Aconiti Lateralis Preparata 3-15 part, Rhizoma Dioscoreae 10-40 part, Radix Aucklandiae 6-40 part, Rhizoma Coptidis 3-15 part, Radix Codonopsis 8-25 part, Herba Agrimoniae 3-30 part, Ootheca Mantidis 3-30 part, dried Alumen 3-30 part.
2. Chinese medicine composition according to claim 1 is made by following materials of weight proportions: 30 parts of Rhizoma Zingiberiss, 10 parts of Os Draconis, 15 parts of Polyporus, 30 parts of Fructus Chebulaes, 15 parts of Semen Myristicaes, 20 parts of Radix Glycyrrhizae Preparatas, 20 parts of Halloysitum Rubrums, 20 parts of Fructus Corni, 20 parts of Fructus Toosendans, 15 parts of Rhizoma Alismatis, 10 parts of Radix Aconiti Lateralis Preparatas, 20 parts of Rhizoma Dioscoreaes, 20 parts of the Radix Aucklandiae, 10 parts of Rhizoma Coptidis, 20 parts of Radix Codonopsis, 15 parts of Herba Agrimoniaes, 15 parts of Ootheca Mantidiss, 15 parts of dried Alumens.
3. the method for preparing claim 1 or 2 described Chinese medicine compositions is characterized in that described each raw material is taken by weighing respectively by described part by weight, is ground into 120 order fine flours more altogether, is prepared into any oral formulations according to the pharmaceutical preparation conventional method.
4. method according to claim 3 is characterized in that described oral formulations is capsule, tablet, granule, powder or pill.
5. method according to claim 4 is characterized in that described oral formulations is a capsule.
6. claim 1 or the 2 described Chinese medicine compositions application in preparation treatment chronic colitis medicine.
7. claim 1 or the 2 described Chinese medicine compositions application in preparation treatment proctitis medicine.
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102145078B (en) * | 2011-03-30 | 2012-07-25 | 张德修 | Traditional Chinese medicine composition for treating chronic colitis |
| CN102526213A (en) * | 2012-01-31 | 2012-07-04 | 庞树有 | Traditional Chinese medicine composition for curing chronic colitis |
| CN104013900A (en) * | 2014-06-26 | 2014-09-03 | 葛晓云 | Preparation for treating chronic enteritis |
| CN107753744A (en) * | 2016-08-16 | 2018-03-06 | 陈琼芳 | A kind of outer medicine for controlling ulcerative colitis |
| CN109985149A (en) * | 2017-12-30 | 2019-07-09 | 程艳青 | A kind of Chinese medicine Tibetan medicine that treating chronic adult's enteritis and processing method |
| CN112316102A (en) * | 2020-12-11 | 2021-02-05 | 北京中医药大学 | Traditional Chinese medicine composition for preventing or treating colitis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1413640A (en) * | 2002-09-08 | 2003-04-30 | 许忠文 | Chinese medicine composition for treating enteritis |
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| CN1413640A (en) * | 2002-09-08 | 2003-04-30 | 许忠文 | Chinese medicine composition for treating enteritis |
Non-Patent Citations (1)
| Title |
|---|
| 邓国良.慢性结肠炎的中医疗法.《中国老年保健医学》.2007,第5卷(第5期),18-19. * |
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