CN103520652B

CN103520652B - Traditional Chinese medicine composition for treating liver cancer

Info

Publication number: CN103520652B
Application number: CN201310508364.6A
Authority: CN
Inventors: 王元华; 李传秋
Original assignee: Individual
Current assignee: Chen Jingjing
Priority date: 2013-10-25
Filing date: 2013-10-25
Publication date: 2015-04-22
Anticipated expiration: 2033-10-25
Also published as: CN103520652A

Abstract

The invention discloses a traditional Chinese medicine composition for treating liver cancer. The traditional Chinese medicine composition for treating the liver cancer is prepared from the following medicinal raw materials by weight: 3-8g of rhizoma sparganii, 15-25g of curcuma zedoary, 10-20g of Chinese polyphaga, 10-25g of oldenlandia diffusa, 17-28g of sculellaria barbata, 5-10g of semen vaccariae, 5-15g of fructus polygoni orientalis and 6-15g of perfoliote knotweed herb. The traditional Chinese medicine composition for treating the liver cancer has the beneficial effects that the traditional Chinese medicine composition is specially used for treating the liver cancer, multiple medicines are appropriately combined, the curative effect of the traditional Chinese medicine composition is improved by using the mutual synergistic effect or resistance effect among the medicines so as to adapt to the treatment requirements of complex illness states, adverse reactions are reduced, and the traditional Chinese medicine composition has an obvious curative effect, good absorption effect without side effects and a better treatment effect on the liver lung and is safe, reliable, simple to prepare and take and beneficial to the timely alleviation of symptoms of diseases of patients.

Description

A kind of Chinese medicine composition of Hepatoma therapy

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition of Hepatoma therapy.

Background technology

Hepatocarcinoma (liver cancer) is the third-largest common cancer that mortality rate is only second to gastric cancer, esophageal carcinoma, and initial symptoms is also not obvious, late period main manifestations be liver pain, weak, become thin, the symptom such as jaundice, ascites.The pathomechanism of hepatocarcinoma comprises in the invasion of six climate exopathogens evil poison, exogenous pathogen, evil solidifying poison knot, with the passing of time become long-pending, and internal organs Qi and blood deficiency, stagnation of dampness due to deficiency of the spleen, qi depression to blood stasis, outside the Pass illustrating that hepatocarcinoma is removed and to be had with hepatitis and extraneous poisonous factor, also declines relevant with autoimmunity.Generally take the operation of doctor trained in Western medicine, chemicotherapy and Chinese Medicine and Clavicular therapy clinically, but patients with terminal is because of cancerous cell diffusion, and cure rate is lower, therefore will accomplish the early discovery of hepatocarcinoma, early diagnosis, early treatment.Carry out the prevention work of hepatocarcinoma, adhere to the prevention of hcc seven word policy of " Guan Shui, Guan Liang, anti-hepatitis ".China depends on operation, radiotherapy and chemotherapy in Hepatoma therapy, but said method is while killing cancerous cell, and human normal cell comes to harm too, and has the Western medicine of antitumaous effect, and side effect is large, and curative effect is not obvious, and somewhat expensive.At present, Chinese medicine in most cases can only play control action to anticancer, for cancer, although can mitigate the disease and pain, curative effect be not good enough.

In prior art, the herbal species of Hepatoma therapy is a lot, such as application number is 201110399307.X, name is called a kind of Chinese medicine of Hepatoma therapy, and its raw material is made up of 12 taste medical materials such as Hericium erinaceus (Bull. Ex Fr.) Pers., Herba Hyperici Japonici, Radix Scutellariae, Herba Lobeliae Chinensis, Rhizoma Polygoni Cuspidati, Semen Persicae, Fructus Crataegi, Testa arachidis hypogaeae, Cortex Dictamni, Herba Hedyotidis Diffusae, Flos Carthami, Cortex Phellodendris; Application number is 201210208240.1, and name is called the Chinese medicine being used for the treatment of hepatocarcinoma, and raw material is made up of Chinese crude drugs such as Cutis Bufonis, Carapax Trionycis, Herb Gynostemmae Pentaphylli, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Herba Scutellariae Barbatae, Rhizoma Polygoni Cuspidati, the Radixs Astragali; As can be seen from upper example, the medicine of existing Hepatoma therapy, most raw material variety is various, and preparation technology is comparatively complicated, and add that some raw material is rare valuable medicinal, to cause the price of medicine higher, patient is difficult to bear.In addition, because some crude drug inherently has very large toxicity, to cause medicine with certain toxicity, often certain side effect is produced to patient.At present, there is no the medicine with same materials compatibility of the present invention.

Summary of the invention

Object of the present invention is exactly to solve the problem, and provides a kind of Chinese medicine composition of Hepatoma therapy, and it has, and good effect, expense are low, the advantage such as have no side effect.

To achieve these goals, the present invention adopts following technical scheme:

A Chinese medicine composition for Hepatoma therapy, is made up of the crude drug of following weight: Rhizoma Sparganii 3-8 gram, Rhizoma Curcumae 15-25 gram, Eupolyphaga Seu Steleophaga 10-20 gram, Herba Hedyotidis Diffusae 10-25 gram, Herba Scutellariae Barbatae 17-28 gram, Semen Vaccariae 5-10 gram, Fructus Polygoni Orientalis 5-15 gram, Herba Polygoni cymosi 6-15 gram.

Preferably, a kind of Chinese medicine composition of Hepatoma therapy, is made up of the crude drug of following weight: Rhizoma Sparganii 6-8 gram, Rhizoma Curcumae 20-25 gram, Eupolyphaga Seu Steleophaga 15-20 gram, Herba Hedyotidis Diffusae 15-25 gram, Herba Scutellariae Barbatae 20-25 gram, Semen Vaccariae 6-8 gram, Fructus Polygoni Orientalis 10-15 gram, Herba Polygoni cymosi 6-12 gram.

More preferred, a kind of Chinese medicine composition of Hepatoma therapy, is made up of the crude drug of following weight: Rhizoma Sparganii 8 grams, Rhizoma Curcumae 22 grams, Eupolyphaga Seu Steleophaga 20 grams, Herba Hedyotidis Diffusae 22 grams, Herba Scutellariae Barbatae 22 grams, Semen Vaccariae 6 grams, Fructus Polygoni Orientalis 13 grams, Herba Polygoni cymosi 10 grams.

The pharmacological action of each component is as follows:

Rhizoma Sparganii: acrid in the mouth; Puckery; Cool.Enter liver.Spleen channel.Lump in the abdomen controlled by Chinese medicine, gathers, distending pain over the hypochondrium, food stagnation distending pain, dysmenorrhea, amenorrhea, and postnatal blood stasis is suffered from abdominal pain, traumatic injury.Cough due to lung-heat controlled by mongolian medicine, asthma abundant expectoration, liver-heat, arteries and veins heat, the hot hectic fever due to YIN-deficiency of consumptive disease, and " precious day " is sick, fracture.

Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel.1) removing blood stasis promoting the circulation of QI to relieve pain: this product effect is similar to Rhizoma Sparganii, but warm concerted effort is comparatively large, can treat amenorrhea due to stagnation of blood stomachache, abdominal mass, gather.2) long-pending eliminating stagnation: this product energy circulation of qi promoting removing food stagnancy pain relieving, for eating accumulation, breast abdominal distention is vexed has a pain.3) removing blood stasis, women's amenorrhea, or the lump in the abdomen addiction block of phlegm-damp congestion condensation.4) promoting the circulation of QI to relieve pain: be suitable for drinking and eating irregularly, the card of gastral cavity abdomen overflow pain.Suitable compatibility, deficient syndrome, the case of a physically strong patient running a high fever.Many raw use.

Eupolyphaga Seu Steleophaga: salty, cold; Slightly poisonous.Return Liver Channel.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.

Herba Hedyotidis Diffusae: bitter sweet, cold.Nontoxic.Enter heart channel, Liver Channel, spleen channel.Dyspnea and cough due to lung-heat; Laryngopharynx swelling and pain; Intestinal carbuncle; Furuncle and phyma skin infection; Venom; The puckery pain of pyretic stranguria; Edema; Dysentery; Intestinal is scorching; Jaundice due to damp-heat; Be good at the multiple cancerous protuberance for the treatment of.

Herba Scutellariae Barbatae: cool in nature, mildly bitter flavor.Return lung, liver, kidney channel.Tool heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the function such as anticancer.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice.

Semen Vaccariae: bitter is flat.Return liver, stomach warp.Promoting the circulation of blood regulating menstruation, reducing swelling and alleviating pain, lactogenesis of invigorating blood circulation, expedite the emergence of stimulating milk secretion, puerperal thymus dredging.

Fructus Polygoni Orientalis: have eliminating mass and relieving fullness eliminating stagnation, clearing away heat to alleviate pain function.For mass in the abdomen abdominal distention, hepatosplenomegaly, the tuberculosis of cervical lymph nodes, quenches one's thirst, stomachache.Consumption 4.5 ~ 9g, heavy dose can to 30g.Suitable amount used externally is endured cream or is smash long-pending, invigorating spleen to remove dampness.Control flank disease amassing, dropsy, has a stomach-ache, lack of appetite abdominal distention, acute catarrhal conjunctivitis, and skin ulcer swells, scrofula.

Herba Polygoni cymosi: bitter in the mouth cool in nature, acid.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.

In technique scheme, Rhizoma Sparganii, Rhizoma Curcumae, Eupolyphaga Seu Steleophaga mainly play function of promoting blood circulation to disperse blood clots, can shift by Tumor suppression; Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Semen Vaccariae, Fructus Polygoni Orientalis, Herba Polygoni cymosi mainly play effect of heat-clearing and toxic substances removing, control and the inflammation eliminated around tumor and infection.

Beneficial effect of the present invention: Chinese medicine of the present invention is specifically designed to Hepatoma therapy, is suitably coordinated by multi-medicament, utilizes the collaborative or resistant function that it is mutual, improve curative effect, to adapt to the treatment requirement of the complicated state of an illness, reduce untoward reaction, evident in efficacy, safe and reliable, preparation is simple, takes simple, good absorbing effect, have no side effect, be conducive to patient and alleviate condition of illness in time, have good therapeutic effect to hepatocarcinoma.

Below in conjunction with embodiment, the invention will be further described; but not limiting the scope of the invention; one of ordinary skill in the art should be understood that; on the basis of technical scheme of the present invention, those skilled in the art do not need to pay various amendment or distortion that creative work can make still within protection scope of the present invention.

Embodiment 1:

A Chinese medicine composition for Hepatoma therapy, is made up of the crude drug of following weight: Rhizoma Sparganii 3 grams, Rhizoma Curcumae 15 grams, Eupolyphaga Seu Steleophaga 10 grams, Herba Hedyotidis Diffusae 10 grams, Herba Scutellariae Barbatae 17 grams, Semen Vaccariae 5 grams, Fructus Polygoni Orientalis 5 grams, Herba Polygoni cymosi 6 grams.

Above-mentioned raw materials is cleaned up, dry disinfection, play powder mixing, make tablet according to a conventional method, quantitatively take.

Embodiment 2:

A Chinese medicine composition for Hepatoma therapy, is made up of the crude drug of following weight: Rhizoma Sparganii 8 grams, Rhizoma Curcumae 25 grams, Eupolyphaga Seu Steleophaga 20 grams, Herba Hedyotidis Diffusae 25 grams, Herba Scutellariae Barbatae 28 grams, Semen Vaccariae 10 grams, Fructus Polygoni Orientalis 15 grams, Herba Polygoni cymosi 15 grams.

Embodiment 3:

A Chinese medicine composition for Hepatoma therapy, is made up of the crude drug of following weight: Rhizoma Sparganii 8 grams, Rhizoma Curcumae 22 grams, Eupolyphaga Seu Steleophaga 20 grams, Herba Hedyotidis Diffusae 22 grams, Herba Scutellariae Barbatae 22 grams, Semen Vaccariae 6 grams, Fructus Polygoni Orientalis 13 grams, Herba Polygoni cymosi 10 grams.

Clinical data:

(1) clinical data

The present inventor carries out clinical observation treatment to 100 routine liver cancer patients, total effective rate 87%.Pass through cytodiagnosis, blood routine examination, hepatic and renal function checks, regularly carrying out the imaging examinations such as rabat, CT, B ultrasonic, three months is a course for the treatment of, more than a course for the treatment of of taking medicine, patient's lump of 74% reduces more than 50%, wherein patient's lump of 42% is eliminated completely, has good QI invigorating simultaneously, enriches blood, the function such as immunity moderation to patient, weak, the alopecia occurred patient after Prophylactic chemotherapy, to feel sick and the General Symptoms such as leukopenia has and prevents preferably and alleviate effect.

(2) Therapeutic Method

Warm water is taken after mixing it with water, one day twice, the tablet that each 3 embodiment of the present invention 3 are developed.Calculate treatment time according to conditions of patients weight, patients with mild takes about 3 months, and severe case serve on 12 months and can fully recover.

(3) curative effect determinate standard

" complete incidence graph ": cases of complete remission, maintains more than surrounding;

" partial rcsponse ": tumor regression more than 50%, maintains surrounding;

" stablize ": tumor regression, not as good as 50%, increases and is no more than 25%;

" deterioration ": tumor increases more than 25%.

(4) therapeutic effect:

Clinical complete remission 45 example, accounts for 45%; Partial rcsponse 25 example, accounts for 25%; Stablize 17 examples, account for 17%; Worsen 13 examples, total effective rate 87%.

The present invention prepares simply, and good absorbing effect is evident in efficacy, and have no side effect, safety is high, is conducive to patient and alleviates condition of illness in time.

Model case:

1, Wang, 51 years old is the hepatocarcinoma initial stage by hospital diagnosis, and take the made tablet of the embodiment of the present invention 3, warm water is taken after mixing it with water, one day twice, each 4 tablets, and basic recovery is normal after two months, continues to take after four months to check, recovers normal.

2, Lee, 58 years old is hepatocarcinoma mid-term by hospital diagnosis, and take the made tablet of the embodiment of the present invention 3, warm water is taken after mixing it with water, one day twice, each 4 tablets, and stable disease after three months, continues to take four months, and basic recovery is normal.

3, grandson, 55 years old is later period of hepatocarcinoma by hospital diagnosis, and take the made tablet of the embodiment of the present invention 3, warm water is taken after mixing it with water, one day twice, each 4 tablets, and check after 5 months, stable disease, continue to take 5 months, mass reduction, cancerous cell has no diffusion.

Claims

1. a Chinese medicine composition for Hepatoma therapy, is characterized in that, is made up of the crude drug of following weight: Rhizoma Sparganii 3-8 gram, Rhizoma Curcumae 15-25 gram, Eupolyphaga Seu Steleophaga 10-20 gram, Herba Hedyotidis Diffusae 10-25 gram, Herba Scutellariae Barbatae 17-28 gram, Semen Vaccariae 5-10 gram, Fructus Polygoni Orientalis 5-15 gram, Herba Polygoni cymosi 6-15 gram.

2. the Chinese medicine composition of a kind of Hepatoma therapy as claimed in claim 1, is made up of the crude drug of following weight: Rhizoma Sparganii 6-8 gram, Rhizoma Curcumae 20-25 gram, Eupolyphaga Seu Steleophaga 15-20 gram, Herba Hedyotidis Diffusae 15-25 gram, Herba Scutellariae Barbatae 20-25 gram, Semen Vaccariae 6-8 gram, Fructus Polygoni Orientalis 10-15 gram, Herba Polygoni cymosi 6-12 gram.

3. the Chinese medicine composition of a kind of Hepatoma therapy as claimed in claim 1, is characterized in that, be made up of the crude drug of following weight: Rhizoma Sparganii 8 grams, Rhizoma Curcumae 22 grams, Eupolyphaga Seu Steleophaga 20 grams, Herba Hedyotidis Diffusae 22 grams, Herba Scutellariae Barbatae 22 grams, Semen Vaccariae 6 grams, Fructus Polygoni Orientalis 13 grams, Herba Polygoni cymosi 10 grams.