CN107260842A - A kind of anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata and its preparation technology - Google Patents

Abstract

A kind of anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata of the present invention and its preparation technology, are machined by processes such as the anti-colorectal cancer oral liquid prescription formulation of compound root of herbaceous peony Sculellaria barbata, materials procurement, raw material processing, raw material tcm and herbal slice extracts active ingredients, the canned, packagings of preparation；The anti-colorectal cancer oral liquid prescription of compound root of herbaceous peony Sculellaria barbata is formulated；7 kinds of 20 grams of the root of herbaceous peony, 20 grams of Sculellaria barbata etc., honey and distillation water consumption, by 5: 5 volume measurements, preservative consumption 0.1%, the buying ratio of 75% alcohol solvent and tcm and herbal slice total amount is 2: 1；Raw material tcm and herbal slice extracts active ingredients, the patent of invention (July 3 2017 applying date) " medicinal herb componentses suit cylinder electric circulation automatic fitration percolating extractor " designed using the applicant, applied carries out seepage pressure effects, extract solution adds auxiliary material to be mixed evenly, carried out with 200 milliliters of volume oral liquid bottles it is canned, pack, it is oral 20 milliliters every time, twice a day.

Description

A kind of anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata and its preparation technology

Technical field

A kind of anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata of the present invention and its preparation technology belong to anti-tumor Chinese herbal preparation system Standby field, more particularly to a kind of anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata and its preparation technology.

Background technology

The incidence of disease of colorectal cancer occupies the 4th in all cancers, is the cancer for betiding rectum and colon.It is clinical Symptom is different because of the type of carcinoma and position, and in addition to abdominal discomfort and stomachache, right side colon is with constitutional symptom, anaemia and abdomen Portion's lump is primary symptom；Left colon is then blocked using enteric cavity, disordered defaecation is notable symptom；The carcinoma of the rectum is then changed with bowl evacuation habit Become, blood stool and mucus are outstanding behaviours；So far, its etiology unknown, the traditional Chinese medical science thinks may be with edible go mouldy food, salt Salt down food, delicious food food or the long-time stimulus because of large intestine chronic disease, and with the passing of time canceration is formed.A kind of present invention compound toad skin tuber of dwarf lilyturf Anti-gastric cancer oral liquid is based on Chinese medical discrimination, from the root of herbaceous peony, Sculellaria barbata, oldenlandia diffusa, the Chinese bulbul, kuh-seng gram, mock-strawberry, honeybee The 7 taste tcm and herbal slices such as honey are prepared into oral liquid, are that many patients play treatment, health-care efficacy.

The content of the invention

The purpose of the present invention is to select the root of herbaceous peony, Sculellaria barbata, oldenlandia diffusa, the Chinese bulbul, kuh-seng gram, mock-strawberry, honey etc. 7 Kind of tcm and herbal slice compositing formula, makes a kind of anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata, with it is antitumor, antiviral, A variety of functions such as anti-inflammatory antiallergic action, antibacterial, enhancing be immune.7 kinds of tcm and herbal slice effects are complementary, and effect is extensive, by the course for the treatment of Often drink, along with necessary dietary adjustments and physical training, while adjusting psychological quality, one, which surely plays liver tumour patient, controls Treatment, health-care effect, mitigate patient mental's burden, improve patients ' life quality.

To achieve these goals, the technical solution adopted by the present invention is：A kind of anti-colorectal cancer mouthful of compound root of herbaceous peony Sculellaria barbata Take liquid preparing process, formulated by oral liquid prescription, materials procurement, raw material processing, raw material extracts active ingredients, extract medicine Adding water, stirring precipitation, oral liquid are prepared, oral liquid filling sterilizes, label is pasted and packaging multiple working procedure is machined；Compound is white The anti-colorectal cancer oral liquid prescription of Chinese herbaceous peony Sculellaria barbata is formulated, 20 grams of the root of herbaceous peony, 20 grams of Sculellaria barbata, 20 grams of oldenlandia diffusa, 20 grams of the Chinese bulbul, 20 grams of kuh-seng, 20 grams of mock-strawberry, honey are equal with distillation water consumption, by 5: 5 volume measurements, preservative consumption 0.1%, 75% ethanol Solvent is 2 times of tcm and herbal slice () total amount except honey similarly hereinafter；Materials procurement：First determine that compound root of herbaceous peony Sculellaria barbata controls colorectal cancer This batch of oral liquid always produce total bottle number, every bottle of capacity, production total capacity, every bottle take number of days, take total number of days, then by formula 7 kinds of daily expenses of tcm and herbal slice are calculated, 6 kinds of total expenses of tcm and herbal slice are calculated by total number of days is taken, always need to use Amount is calculated the expense of every kind of tcm and herbal slice by formula rate, and graded kind is purchased, the various tcm and herbal slices of buying The quality index and specification standards of every kind of tcm and herbal slice are had to comply with, without going mouldy, no disease and pests harm, free from admixture, pollution-free；75% It is 2: 1 that etoh solvent, which is purchased with tcm and herbal slice total amount buying ratio,；Raw material are processed：In addition to honey, distilled water, preservative, Every kind of tcm and herbal slice is carried out selected and dried, after being sufficiently mixed uniformly, first crushed with 8 millimeters of particle diameter pulverizers, then with 4 in the least Grain of rice footpath pulverizer is crushed standby；Raw material tcm and herbal slice extracts active ingredients, take ethanol extract from water precipitation to carry out, using this Shen " medicinal herb componentses are set with the automatic mistake of cylinder electric circulation to the patent of invention (July 3 2017 applying date) for asking someone to design, apply Filter percolating extractor " carry out seepage pressure effects；The device is followed by percolating extractor support, suit cylinder percolating device, electric pump Ring percolating device, diacolation solution automatic filtering unit, temperature automatically controlled hot water circulating heating device, diacolation solvent evaporation separation dress Put, the part of diacolation solvent condensate recycling device seven is constituted；The percolating extractor operation technological process is：1. diacolation solution is closed Control valve-→ opens charging closure-→ meter feedstock loading inner cylinder-→ layering loading actual situation uniform-→ and adds diacolation solvent Drench be slowly added in circular groove-→ circular groove diacolation solvent-→ solvent uniformly drench into raw material-→ push down circular groove should not float-→ it is molten Agent, which is added to, no longer drenches into 5 centimetres away from circular groove bottom only-→ and rotates circular hole in the middle part of closure to drenching into circular groove inner edge-→ and open diacolation Solution circulation pump-→ regulation diacolation solution circulating valve does not make diacolation solution overflow only-→ closing diacolation solution circulation pump-→ closing Charging closure penetrate screw tightening-→ stand diacolation 36 hours-→ open diacolation solution circulation pump circulatory displacement 36 hours-→ Close diacolation solution circulation pump-→ open diacolation solution control valve-→ diacolation solution through the screen pack automatic fitration of internal barrel bottom-→ Through diacolation solution control valve ,-→ flows into diacolation solution evaporative cylinder top screen pack natural filtration-→ filtered fluid and flows into diacolation solution Open charging closure-→ and open diacolation solution circulation pump-→ and determine whether internal barrel bottom screen pack filters in evaporative cylinder bottom-→ Terminate-→ and 2. terminate filtering closing diacolation solution control valve-→ addition new diacolation solvent-→ progress secondary cycle seepage pressure effects - → opens diacolation solution control valve-→ secondary oozes after the completion of (operating process is identical with first time)-→ secondary cycle seepage pressure effects Solution of filtering through the screen pack automatic fitration of internal barrel bottom-→ flow into the top screen pack natural filtration of diacolation solution evaporative cylinder-→ it is secondary Diacolation solution flow into diacolation solution evaporative cylinder bottom-→ mixed with first time diacolation solution-→ 3. taking-up inner cylinder to pour out the dregs of a decoction clear Wash-→ inner cylinder is reentered into outer barrel-→ closes diacolation solution control valve-→ meter feedstock and load inner cylinder-→ and enter next diacolation Extraction procedure-→ secondary diacolation solution evaporative cylinder self-filtering net filtration terminate-→ 4. connect water source-→ to boiler, hot water Groove, condenser add water-→ unlatching electromagnetic stove to boiler heating-→ unlatching hot water circulating pump-→ boiler and hot water storgae hot water Start the cycle over-→ to diacolation solution evaporative cylinder heating-→ 5. open automatic temperature control instrument-→ regulation temperature controller high temperature to 90 DEG C, it is low Temperature to 80 DEG C-→ hot water storgae water temperature rise to 90 DEG C of electromagnetic stoves close automatically-→ hot water storgae water temperature is down to 80 DEG C of electromagnetic stoves and opens automatically Open-→ evaporative cylinder diacolation solution solvent evaporation-→ solvent evaporate gas through gas delivery pipe-→ 6. gas feeding condenser solvent It is molten into condenser condensation that gas merging chamber-→ solvent gas is condensed into liquid-→ liquid into condenser spiral condensing tube Agent collecting chamber-→ inflow condensing solvent recovery cylinder-→ is put into condensing solvent storage barrel-→ recycling or storage-→ is 7. opened Diacolation solution evaporative cylinder bottom valve-→ always extracts medicine and is put into the storage barrel-heavy agitator addition of → heavy agitator-→ water of preparation water Account for and extract the distilled water-→ of medicine 60% and be slowly added to extract medicine and quickly stir-→ the loading precipitation cylinder-→ that stirs and be put into 0--5 DEG C refrigerator or freezer low-temperature precipitation-→ precipitation completion pour out supernatant-→ the anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata is total Extract medicine；The anti-large intestine cancer treating oral liquid finished medicines of compound root of herbaceous peony Sculellaria barbata are prepared：It is total from oral liquid after total extraction medicine is measured by volume Subtracted in capacity, residual volume amount, honey and distilled water addition capacity are calculated in 5: 5 ratio, preservative presses 0.1% consumption Calculate；It is standby that stainless steel cylindrical vessel is risen with 300-400, the total extraction medicine measured, honey, distilled water, preservative are added not Become rusty steel cylindrical vessel, is mixed, first stirring at low speed during stirring, and constantly regulate is to high-speed stirred, until being sufficiently stirred for It is even.The anti-colorectal cancer oral liquid filling sterilization packaging of compound root of herbaceous peony Sculellaria barbata：The oral liquid finished product stirred is added into filling dress Put, oral liquid bottling capping is carried out with 200 milliliters of volumetric flasks, the anti-large intestine cancer treating oral liquid finished product of compound root of herbaceous peony Sculellaria barbata is obtained；By bottle Oral liquid finished product is filled through high-temperature sterilization, adhesive label, mounted box vanning, storage preserves sale.The anti-colorectal cancer of compound root of herbaceous peony Sculellaria barbata Oral liquid is taken：Oral 20 milliliters every time, 1 twice.

According to《Chinese book on Chinese herbal medicine》Record：The root of herbaceous peony is the root of Paeoniaceae plant peony (cultivation product) and Peony.Contain Chinese herbaceous peony Glucoside, oxidized paeoniflorin glycosides, benzoylpaeoniflorin, albiflorin, Paeoniflorin is without ketone, nutgall acyl Paeoniflorin, β-pinane -10- alkenyls-β-nest Dish glucoside, lactiflorin, paeonilactone A, B, C, cupreol, Daucosterol.Also get 1,2,3,6- tetra- from the tannin of root not eat Sub- acyl glucose, 1,2,3,4,6- five galloyl glucose and corresponding six galloyl glucose and seven nutgalls Acyl glucose etc..Cachou extract containing dextrorotation and volatile oil again.Volatile oil mainly contains benzoic acid, paeonol and other alcohols and phenols Composition totally 33.Sculellaria barbata is the herb of labiate Sculellaria barbata.Contain carthamin, isocarthamidin, high mountain baicalein, high mountain Yellow official seal glucoside, cupreol, stearic acid, alkaloid [1,2] polysaccharide [3] etc..According to another report, from the isolated Chinese radix scutellariae of aerial part Element, rivularin, Sculellaria barbata kind element, naringenin, apiolin, dinatin, eriodictyol, sweet-scented osmanthus straw rope, 5,7,4- trihydroxies- 8- methoxy flavanone 4- hydroxyl wogonins, 7- gate of a lane base -5,8- dimethoxy flavones, p- great base benzene first Tibet, p- great base Benzylacetone, p-coumaric acid, protocatechuic acid, energy tartaric acid phytosterol, phytosterol β-D-Glucose glucoside etc.；Oldenlandia diffusa For the whole herb with root of dicotyledon medicine madder wort oldenlandia diffusa.Containing asperuloside, asperuloside acid removes acetate Asperuloside acid, all square rafter glucoside, Chinese Fevervine Herb time glucoside, Chinese Fevervine Herb time glucoside methyl esters, 6-O- p- hydroxyl cinnamyl Chinese Fevervine Herb time glucoside first Ester, 6-O- p- methoxyl group cinnamyl Chinese Fevervine Herb time glucoside methyl esters, 6-O- asafoetide acyls Chinese Fevervine Herb time glucoside methyl esters, 2- methyl -3- hydroxyl anthracenes Quinone, 2- methyl -3- methoxy anthraquinones, 2- methyl -3- hydroxyl -4- methoxy anthraquinones etc. [1-3], and ursolic acid, cupreol, Hentriacontane, stigmasterol, oleanolic acid, cupreol-β-glycoside, p-coumaric acid etc. [5,6]；The Chinese bulbul is Ranunculaceae The root of the plant Chinese bulbul；Containing anemoside A, B, C, D, 3-O- α-L- rhamnopyranoses-(1 → 2)-α-L- pyrans is Arabic - 3 β of sugar, 23- dihydroxy-Δ 20 (29)-lupene -28- acid, Pulchinenoside A3B B4, B4, saponin 1,2, betulic acid -3-O- α-L arabopyranose glucosides, betulic acid, 3- oxo betulic acids, Daucosterol, Anemonin, protoanemonin etc., mainly Anticancer component is Pulchinenoside A3B B4；Kuh-seng is the root of legume kuh-seng.Contain matrine, oxymatrine, N- oxidation Chinese scholartrees Root alkali, Sophoridine, the other matrine of dextrorotation, dextrorotation Iosmatrine, dextrorotation sophoranl, sophoranl N- oxides, left-handed sophocarpine are left Revolve sophoramine, dextrorotation-N-Methylcytisine, left-handed anagyrine, bap-iifoline.Also contain a variety of flavone compounds in root：It is bitter Join new alcohol, kuh-seng alcohol drops in kuh-seng chalcone, kuh-seng chalcone alcohol, kuh-seng alcohol, neokurarinol, isokurarinone, formoononetin, Kurarinone, Vexibinol, the new alcohol C of methyl kuh-seng, 1- maackiains, trifolirhizin and trifolirhizin malonate are bitter Anhydroicartin, Xanthohumol, different fulvic acid, cyanidenon -7- glycosides drop in ginseng element, different anhydroicartin.In addition, Also contain triterpenoid saponin in root：Kuh-seng saponin, soyasaponins and quinones：Kuh-seng quinone；Mock-strawberry is rosaceous plant snake The herb of the certain kind of berries.Contain methoxyl group aphyllidine, oligomeric condensed tannin, ellagitannin, total protein, total unstructuredness carbon water Compound, gallic acid is sugared, pentose, uronic acid, protein, protein tannin polysaccharide, phenolic substance, and ursolic acid, committee are contained again Mound dish acid, multiflora rose glucose ester, Rosa roxburghii glucoside F, 6- methoxyl group naringenin, farrerol, cupreol, stearic acid, white birch glucoside, snake The certain kind of berries and nutgall glucoside A, B, Kaempferol-O- rutinosides and Kaempferol-O- thorn sophoriobiosides；Honey is in Apidae animal The honey that the close honeybee of China or apis mellifera are made.It is main to contain glucose, fructose containing the glucide led in honeycomb；Other Also contain sucrose, dextrin, organic acid, protein, volatile oil, wax, pollen grain, vitamin B1, B2, B6, C, K, H, amylase turns people Enzyme, peroxidase, esterase, growth stimulant, acetylcholine, nicotinic acid, pantothenic acid, carrotene, inorganic elements calcium, sulphur, phosphorus, magnesium, Potassium, sodium, iodine etc..

The beneficial effects of the invention are as follows：Above-mentioned 7 kinds of Chinese medicine prescriptions, the root of herbaceous peony has antitumor and antimutagenesis, liver protection With detoxication, antibacterial action, suppress the effect of platelet aggregation, it is hypotensive activity, oxygen lack resistant function, two-way to immunologic function Adjustment effect, anti-inflammatory, antiulcer action, spasmolysis and analgesia effect etc.；Sculellaria barbata has clearing heat and detoxicating；Dissipate stasis of blood hemostasis；Inducing diuresis to remove edema Effect.Curing cancers, ascites, lung carbuncle；Acute appendicitis；Scrofula；Spit blood；Bleeding from five sense organs or subcutaneous tissue；Blood strangury；Oedema；Heat toxin carbuncle swells；Have sore throat；Poisonous snake stings Wound；Traumatic injury etc..Oldenlandia diffusa has anticancer swollen, anti inflammatory immunity, anti-inflammation, clearing heat and detoxicating；Dampness removing.Control acute appendicitis；Furuncle Swollen sore；Puckery pain of heat gonorrhea；Oedema；Dysentery；Enteritis；Jaundice with damp-heat pathogen；Dyspnea and cough due to lung-heat；Abscess of throat etc.；The Chinese bulbul have it is antitumor, Antivirus action, antibacterial action, calmness, analgesia and anti-spasm effect, it is clearing heat and detoxicating；Remove heat from the blood and relieve diarrhea；Removing dampness and destroying parasites etc. acts on；It is bitter Ginseng is with antitumor action, effect in increasing leukocyte, expansion blood vessel and the protective effect to acute myocardial ischemia；It is antihypertensive effect, flat Breathe heavily phlegm-dispelling functions, stable effect, anti-allergic effects, to adjust immunization, ulcer function, antiinflammatory action, antibacterial action, heat-clearing dry Wet, wind dispelling insecticide；Mock-strawberry has antitumaous effect, enhancing immunologic function, antibacterial action, and clearing heat and detoxicating, eliminating stasis to subdue swelling, cool blood is stopped Blood, controls pyreticosis, and frightened epilepsy is coughed, spitted blood, abscess of throat, dysentery, carbuncle swells, furunculosis, furuncle etc..Honey have lipotropy, The composition of blood can be improved, promote heart and brain and vascular function；There is protective effect to liver, liver cell regeneration can be promoted；Can be rapid Regain one's strength of body, dispelling fatigue builds up one's resistance to disease；The also effect of sterilizing；The skin damage of moderate can be treated, Particularly scald；Sleep can be improved；It can also relax bowel.7 kinds of tcm and herbal slices of the above have anticancer, anti-aging, disease-resistant Toxic action, antibacterial action etc. are acted on；Effect is complementary, and effect is extensive, is often drunk by the course for the treatment of, along with necessary physical training, regulation Psychological quality, one surely plays anticancer, health-care effect, mitigates patient mental's burden, improves patients ' life quality.

Embodiment

Specific embodiment

1st, formulating the anti-colorectal cancer oral liquid prescription of compound root of herbaceous peony Sculellaria barbata is：20 grams of the root of herbaceous peony, 20 grams of Sculellaria barbata, oldenlandia 20 grams of grass, 20 grams of the Chinese bulbul, 20 grams of kuh-seng, 20 grams of mock-strawberry, honey are equal with distillation water consumption, by 5: 5 volume measurements, preservative Consumption 0.1%.

2nd, it is 1000 bottles to determine the anti-large intestine cancer treating oral liquid output of this batch compound root of herbaceous peony Sculellaria barbata, per bottled 200 milliliters, Oral liquid total amount need to be prepared altogether for 200 liters.

3rd, the tcm and herbal slice as needed for the anti-large intestine cancer treating oral liquid output of this batch compound root of herbaceous peony Sculellaria barbata and recipe calculation Total amount is 600 kilograms, and calculating 5 kinds of tcm and herbal slice amount of purchases by formula rate is respectively：From Chinese herbaceous peony double centner, Sculellaria barbata 100 Kilogram, oldenlandia diffusa double centner, Chinese bulbul double centner, kuh-seng double centner, mock-strawberry double centner, the ratio of honey and distilled water Example is 5: 5, waits active ingredients from traditional Chinese medicinal to measure buying by volume after the completion of extracting；Preservative consumption is 0.1%, and 75% ethanol is molten Agent purchases 1200 liters, recycles.

4th, the anti-large intestine cancer treating oral liquid tcm and herbal slice processing of compound root of herbaceous peony Sculellaria barbata：Every kind of tcm and herbal slice is carried out selected And drying, after being sufficiently mixed uniformly, first crushed with 6 millimeters of particle diameter pulverizers, then crush standby with 3 millimeters of particle diameter pulverizers.

5th, the anti-large intestine cancer treating oral liquid tcm and herbal slice extracts active ingredients of compound root of herbaceous peony Sculellaria barbata：Ethanol extract from water precipitation is taken to enter OK, " medicinal herb componentses suit cylinder is electronic for the patent of invention (July 3 2017 applying date) designed using the applicant, applied Circulate automatic fitration percolating extractor " carry out seepage pressure effects；The device is filled by percolating extractor support, suit cylinder diacolation Put, electric pump circulatory displacement device, diacolation solution automatic filtering unit, temperature automatically controlled hot water circulating heating device, diacolation solvent steam Send out separator, the part of diacolation solvent condensate recycling device seven composition；The percolating extractor operation technological process is：1. close Diacolation solution control valve-→ is opened charging closure-→ meter feedstock loading inner cylinder-→ layering loading actual situation uniform-→ and added Diacolation solvent, which drenches, to be slowly added to diacolation solvent-→ solvent and uniformly drenches into raw material-→ and push down circular groove and should not float in circular groove-→ circular groove Rise-→ solvent add to no longer drench into 5 centimetres away from circular groove bottom only-→ by circular hole in the middle part of closure rotate to drench into circular groove inner edge-→ Opening diacolation solution circulation pump-→ regulation diacolation solution circulating valve does not make diacolation solution overflow only-→ closing diacolation solution circulation Pump-→ closes charging closure and penetrates 36 hours-→ unlatching diacolation solution circulation pump circulatory displacements of screw tightening-→ standing diacolation 36 hours-→ close diacolation solution circulation pump-→ open diacolation solution control valve-→ diacolation solution through internal barrel bottom screen pack from Dynamic filtering-→ through diacolation solution control valve ,-→ flows into diacolation solution evaporative cylinder top screen pack natural filtration-→ filtered fluid and flowed into Open charging closure-→ and open diacolation solution circulation pump-→ and determine internal barrel bottom screen pack in diacolation solution evaporative cylinder bottom-→ Whether filtering, which terminates ,-→ is 2. terminated filtering and closes diacolation solution control valve-→ and add new diacolation solvent-→ and carry out secondary cycle to ooze Filter after the completion of extraction (operating process is identical with first time)-→ secondary cycle seepage pressure effects-→ open diacolation solution control valve-→ Secondary diacolation solution is through the screen pack automatic fitration of internal barrel bottom-→ flow into the top screen pack natural filtration of diacolation solution evaporative cylinder- → secondary diacolation solution flows into diacolation solution evaporative cylinder bottom-→ and-→ is mixed with first time diacolation solution 3. taking-up inner cylinder is poured out Dregs of a decoction cleaning-→ inner cylinder is reentered into outer barrel-→ and closed under diacolation solution control valve-→ meter feedstock loading inner cylinder-→ entrance Secondary seepage pressure effects program-→ secondary diacolation solution evaporative cylinder self-filtering net filtration terminate-→ 4. connect water source-→ to hot water Case, hot water storgae, condenser add water-→ unlatching electromagnetic stove to boiler heating-→ unlatching hot water circulating pump-→ boiler and hot water Groove hot water starts the cycle over-→, and to diacolation solution evaporative cylinder heating-→, 5. unlatching automatic temperature control instrument-→ adjusts temperature controller high temperature to 90 DEG C, low temperature to 80 DEG C-→ hot water storgae water temperature rise to 90 DEG C of electromagnetic stoves close automatically-→ hot water storgae water temperature be down to 80 DEG C of electromagnetic stoves from Dynamic unlatchings-→ evaporative cylinder diacolation solution solvent evaporation-→ solvent evaporation gas through gas delivery pipe-→ 6. gas send into condenser It is cold into condenser that solvent gas merging chamber-→ solvent gas is condensed into liquid-→ liquid into condenser spiral condensing tube Solidifying solvent collecting chamber-→ flow into condensing solvent recovery cylinder-→ be put into condensing solvent storage barrel-→ recycle or storage-→ 7. Open diacolation solution evaporative cylinder bottom valve-→ coarse extraction medicine and be put into storage barrel-→ heavy agitator of the heavy agitator-→ water of preparation water Add to account for the distilled water-→ for extracting medicine 60% and be slowly added to extract medicine and quickly stir-→ the loading precipitation cylinder-→ that stirs and be put into Supernatant-→ is poured out in 0--5 DEG C of refrigerator or freezer low-temperature precipitation-→ precipitation completion, and it is oral to obtain the anti-colorectal cancer of compound root of herbaceous peony Sculellaria barbata Liquid always extracts medicine.

6th, the anti-large intestine cancer treating oral liquid finished medicines of compound root of herbaceous peony Sculellaria barbata are prepared：It is total to extract after medicine measures by volume, from oral Subtracted in 200 liters of liquid total capacity, residual volume amount, honey and distilled water addition capacity are calculated in 5: 5 ratio, preservative is pressed 0.1% consumption is calculated；It is standby that stainless steel cylindrical vessel is risen with 300-400, by the thick finished medicines, honey, distilled water, the anti-corrosion that measure Agent adds stainless steel cylindrical vessel, is mixed, first stirring at low speed during stirring, and constantly regulate is to high-speed stirred, until filling Divide and stir.

7th, the anti-colorectal cancer oral liquid filling sterilization packaging of compound root of herbaceous peony Sculellaria barbata：The oral liquid finished product stirred is added Filling apparatus, the bottling capping of compound indigo radix scutellariae anti-leukocythemia oral liquid is carried out with 200 milliliters of volumetric flasks；Obtain the compound root of herbaceous peony half The anti-large intestine cancer treating oral liquid finished product of lotus；By the anti-large intestine cancer treating oral liquid finished product of bottled compound root of herbaceous peony Sculellaria barbata through high-temperature sterilization, label adhering Label, mounted box vanning, storage preserves sale.

8th, the anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata is taken：Oral 20 milliliters every time, 1 twice.

Claims (7)

1. the anti-colorectal cancer oral liquid prescription of compound root of herbaceous peony Sculellaria barbata is formulated, it is characterized in that：20 grams of the root of herbaceous peony, 20 grams of Sculellaria barbata, spend in vain 20 grams of HERBA HEDYOTIS DIFFUSAE, 20 grams of the Chinese bulbul, 20 grams of kuh-seng, 20 grams of mock-strawberry, honey and distillation water consumption, by 5: 5 volume measurements, preservative Consumption 0.1%.

2. the anti-large intestine cancer treating oral liquid materials procurement of compound root of herbaceous peony Sculellaria barbata, it is characterized in that：First determine that compound root of herbaceous peony Sculellaria barbata resists This batch of large intestine cancer treating oral liquid always produce total bottle number, every bottle of capacity, production total capacity, every bottle take number of days, take total number of days, press It is formulated and takes total number of days and calculate the total expense of every kind of tcm and herbal slice, graded kind is purchased, the various Chinese medicines of buying Medicine materical crude slice has to comply with the quality index and specification standards of every kind of tcm and herbal slice, without going mouldy, no disease and pests harm, free from admixture, pollution-free； It is 2: 1 that 75% etoh solvent, which is purchased with tcm and herbal slice total amount buying ratio,.

3. the anti-large intestine cancer treating oral liquid raw material processing of compound root of herbaceous peony Sculellaria barbata, it is characterized in that：In addition to honey, distilled water, preservative, Every kind of tcm and herbal slice is carried out selected and dried, after being sufficiently mixed uniformly, first crushed with 8 millimeters of particle diameter pulverizers, then with 4 in the least Grain of rice footpath pulverizer is crushed standby.

4. the anti-large intestine cancer treating oral liquid tcm and herbal slice extracts active ingredients of compound root of herbaceous peony Sculellaria barbata, it is characterized in that：Take alcohol water lift Heavy method is carried out, patent of invention (July 3 2017 applying date) " the medicinal herb componentses suit circle designed using the applicant, applied Cylinder electric circulation automatic fitration percolating extractor " carries out seepage pressure effects；The device is by percolating extractor support, suit cylinder Percolating device, electric pump circulatory displacement device, diacolation solution automatic filtering unit, temperature automatically controlled hot water circulating heating device, diacolation Solvent evaporating separation device, the part of diacolation solvent condensate recycling device seven composition；The percolating extractor operation technological process is： 1. close diacolation solution control valve-→ open charging closure-→ meter feedstock load inner cylinder-→ layering load actual situation it is uniform- → add diacolation solvent and drench and be slowly added to diacolation solvent-→ solvent in circular groove-→ circular groove and uniformly drench into raw material-→ to push down circular groove Should not float-→ solvent add to no longer drench 5 centimetres away from circular groove bottom only-→ circular hole in the middle part of closure is rotated to drenching in circular groove Diacolation solution circulation pump-→ regulation diacolation solution circulating valve is opened on side-→ does not make diacolation solution overflow only-→ closing diacolation solution Circulating pump-→ closes charging closure and penetrates-→ the unlatching diacolation solution circulation pump circulation in 36 hours of screw tightening-→ standing diacolation Diacolation 36 hours-→ closes diacolation solution circulation pump-→ and opens diacolation solution control valve-→ diacolation solution and filtered through internal barrel bottom Net automatic fitration-→ through diacolation solution control valve-→ diacolation solution inflow evaporative cylinder top screen pack natural filtration-→ filtered fluid Flow into diacolation solution evaporative cylinder bottom-→ opening charging closure-→ unlatching diacolation solution circulation pump-→ and determine internal barrel bottom mistake Whether filter screen, which filters, which is terminated ,-→ 2. terminates filtering and closes diacolation solution control valve-→ and add new diacolation solvent-→ to carry out secondary follow - → opens the control of diacolation solution after the completion of ring seepage pressure effects (operating process is identical with first time)-→ secondary cycle seepage pressure effects Valve-→ secondary diacolation solution through the screen pack automatic fitration of internal barrel bottom-→ to flow into diacolation solution evaporative cylinder top screen pack natural Filtering-→ secondary diacolation solution flows into diacolation solution evaporative cylinder bottom-→ and-→ is mixed with first time diacolation solution and 3. takes out inner cylinder Pour out dregs of a decoction cleaning-→ inner cylinder and be reentered into outer barrel-→ and close diacolation solution control valve-→ meter feedstock and load inner cylinder-→ Enter next seepage pressure effects program-→ secondary diacolation solution evaporative cylinder self-filtering net filtration terminate-→ 4. connect water source-→ to heat Water tank, hot water storgae, condenser add water-→ unlatching electromagnetic stove to boiler heating-→ unlatching hot water circulating pump-→ boiler and heat Tank hot water starts the cycle over-→ to diacolation solution evaporative cylinder heating-→ 5. open automatic temperature control instrument-→ regulation temperature controller high temperature to 90 DEG C, low temperature to 80 DEG C-→ hot water storgae water temperature rise to 90 DEG C of electromagnetic stoves close automatically-→ hot water storgae water temperature is down to 80 DEG C of electromagnetic stoves Automatic opening-→ evaporative cylinder diacolation solution solvent evaporation-→ solvent evaporate gas through gas delivery pipe-→ 6. gas feeding condensation Device solvent gas merging chamber-→ solvent gas is condensed into liquid-→ liquid into condenser spiral condensing tube and enters condenser Condensing solvent collecting chamber-→ flow into condensing solvent recovery cylinder-→ be put into condensing solvent storage barrel-→ recycle or storage-→ 7. open diacolation solution evaporative cylinder bottom valve-→ coarse extraction medicine and be put into storage barrel-→ heavy stirring of the heavy agitator-→ water of preparation water Device adds to account for the distilled water-→ for extracting medicine 60% and be slowly added to extract medicine and quickly stirs-→ the loading precipitation cylinder-→ that stirs and put Enter 0--5 DEG C of refrigerator or freezer low-temperature precipitation-→ precipitation completion pours out supernatant-→ and obtains the anti-colorectal cancer mouthful of compound root of herbaceous peony Sculellaria barbata Take liquid and always extract medicine.

5. the anti-large intestine cancer treating oral liquid finished medicines of compound root of herbaceous peony Sculellaria barbata are prepared；It is characterized in that：After total extraction medicine is measured by volume, from Subtracted in 200 liters of oral liquid total measurement (volume) amount, residual volume amount, honey and distillation water capacity, preservative are calculated in 5: 5 ratio Calculated by 0.1% consumption；It is standby that stainless steel cylindrical vessel is risen with 300-400, by the total extraction medicine measured, honey, distilled water, anti- Rotten agent adds stainless steel cylindrical vessel, is mixed, first stirring at low speed during stirring, constantly regulate to high-speed stirred, until Stir.

6. the anti-colorectal cancer oral liquid filling sterilization packaging of compound root of herbaceous peony Sculellaria barbata；It is characterized in that：By the oral liquid stirred into Product add filling apparatus, and oral liquid bottling capping is carried out with 200 milliliters of volumetric flasks；Obtain the anti-colorectal cancer of compound root of herbaceous peony Sculellaria barbata oral Liquid finished product；By bottled oral liquid finished product through high-temperature sterilization, adhesive label, mounted box vanning, storage preserves sale.

7. the anti-large intestine cancer treating oral liquid of compound root of herbaceous peony Sculellaria barbata is taken；It is characterized in that：Oral 20 milliliters every time, 1 twice.