CH616157A5 - - Google Patents
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- Publication number
- CH616157A5 CH616157A5 CH794275A CH794275A CH616157A5 CH 616157 A5 CH616157 A5 CH 616157A5 CH 794275 A CH794275 A CH 794275A CH 794275 A CH794275 A CH 794275A CH 616157 A5 CH616157 A5 CH 616157A5
- Authority
- CH
- Switzerland
- Prior art keywords
- propylthio
- sheep
- parasites
- dictyocaulus
- animals
- Prior art date
Links
- 241001494479 Pecora Species 0.000 claims description 16
- 241001465754 Metazoa Species 0.000 claims description 14
- 230000000694 effects Effects 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 11
- HXHWSAZORRCQMX-UHFFFAOYSA-N albendazole Chemical compound CCCSC1=CC=C2NC(NC(=O)OC)=NC2=C1 HXHWSAZORRCQMX-UHFFFAOYSA-N 0.000 claims description 10
- 150000001875 compounds Chemical class 0.000 claims description 9
- -1 alkyl radical Chemical class 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 241001147667 Dictyocaulus Species 0.000 claims description 7
- 241000243789 Metastrongyloidea Species 0.000 claims description 7
- 244000045947 parasite Species 0.000 claims description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 6
- 241001137882 Nematodirus Species 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 6
- YXXYBJDTATZCOJ-UHFFFAOYSA-N 4-propylsulfanylbenzene-1,2-diamine Chemical compound CCCSC1=CC=C(N)C(N)=C1 YXXYBJDTATZCOJ-UHFFFAOYSA-N 0.000 claims description 5
- 241000243976 Haemonchus Species 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- XMJHPCRAQCTCFT-UHFFFAOYSA-N methyl chloroformate Chemical compound COC(Cl)=O XMJHPCRAQCTCFT-UHFFFAOYSA-N 0.000 claims description 4
- ZSYJMXLJNPEAGP-UHFFFAOYSA-N methyl n-cyanocarbamate Chemical compound COC(=O)NC#N ZSYJMXLJNPEAGP-UHFFFAOYSA-N 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
- 241000283690 Bos taurus Species 0.000 claims description 3
- 210000001035 gastrointestinal tract Anatomy 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- RKMOQLOKJZARIG-UHFFFAOYSA-N 6-propylsulfanyl-1h-benzimidazol-2-amine Chemical compound CCCSC1=CC=C2N=C(N)NC2=C1 RKMOQLOKJZARIG-UHFFFAOYSA-N 0.000 claims description 2
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 claims description 2
- 241000283086 Equidae Species 0.000 claims description 2
- 241000282887 Suidae Species 0.000 claims description 2
- ATDGTVJJHBUTRL-UHFFFAOYSA-N cyanogen bromide Chemical compound BrC#N ATDGTVJJHBUTRL-UHFFFAOYSA-N 0.000 claims description 2
- 210000003608 fece Anatomy 0.000 claims description 2
- 230000001418 larval effect Effects 0.000 claims description 2
- 125000004414 alkyl thio group Chemical group 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- WEYSQARHSRZNTC-UHFFFAOYSA-N 1h-benzimidazol-2-ylcarbamic acid Chemical class C1=CC=C2NC(NC(=O)O)=NC2=C1 WEYSQARHSRZNTC-UHFFFAOYSA-N 0.000 claims 1
- 241000282472 Canis lupus familiaris Species 0.000 claims 1
- 241000283707 Capra Species 0.000 claims 1
- 241001465696 Dictyocaulidae Species 0.000 claims 1
- 241000282326 Felis catus Species 0.000 claims 1
- 241000545648 Filaroididae Species 0.000 claims 1
- 241000219823 Medicago Species 0.000 claims 1
- 235000017587 Medicago sativa ssp. sativa Nutrition 0.000 claims 1
- 241000556231 Metastrongylidae Species 0.000 claims 1
- 241000556230 Metastrongylus Species 0.000 claims 1
- 241001617421 Protostrongylus Species 0.000 claims 1
- 241000725681 Swine influenza virus Species 0.000 claims 1
- 230000002378 acidificating effect Effects 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 238000007796 conventional method Methods 0.000 claims 1
- 235000013601 eggs Nutrition 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Substances C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 125000004430 oxygen atom Chemical group O* 0.000 claims 1
- 239000008188 pellet Substances 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- 230000037396 body weight Effects 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 description 3
- 229960004546 thiabendazole Drugs 0.000 description 3
- 235000010296 thiabendazole Nutrition 0.000 description 3
- 239000004308 thiabendazole Substances 0.000 description 3
- 241000242711 Fasciola hepatica Species 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- 230000034994 death Effects 0.000 description 2
- 231100000517 death Toxicity 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 230000008029 eradication Effects 0.000 description 2
- 244000000050 gastrointestinal parasite Species 0.000 description 2
- 229960001614 levamisole Drugs 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- SUVIGLJNEAMWEG-UHFFFAOYSA-N propane-1-thiol Chemical compound CCCS SUVIGLJNEAMWEG-UHFFFAOYSA-N 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- NLCPQMUVBQILMA-UHFFFAOYSA-N 2-nitro-5-propylsulfanylaniline Chemical compound CCCSC1=CC=C([N+]([O-])=O)C(N)=C1 NLCPQMUVBQILMA-UHFFFAOYSA-N 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- 241000244188 Ascaris suum Species 0.000 description 1
- 241000416162 Astragalus gummifer Species 0.000 description 1
- 241000999616 Avitellina Species 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 241000242722 Cestoda Species 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 241000180412 Dictyocaulus filaria Species 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 241000243974 Haemonchus contortus Species 0.000 description 1
- 241001137878 Moniezia Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- RAOCRURYZCVHMG-UHFFFAOYSA-N N-(6-propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester Chemical compound CCCOC1=CC=C2N=C(NC(=O)OC)NC2=C1 RAOCRURYZCVHMG-UHFFFAOYSA-N 0.000 description 1
- 241000244206 Nematoda Species 0.000 description 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 1
- 241000282849 Ruminantia Species 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 150000004985 diamines Chemical class 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 208000006275 fascioliasis Diseases 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- WEXOIPBOPIVXDZ-UHFFFAOYSA-N hydron;4-propylsulfanylbenzene-1,2-diamine;chloride Chemical compound Cl.CCCSC1=CC=C(N)C(N)=C1 WEXOIPBOPIVXDZ-UHFFFAOYSA-N 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US480646A US3915986A (en) | 1974-06-19 | 1974-06-19 | Methyl 5-propylthio-2-benzimidazolecarbamate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH616157A5 true CH616157A5 (pt) | 1980-03-14 |
Family
ID=23908789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH794275A CH616157A5 (pt) | 1974-06-19 | 1975-06-18 |
Country Status (33)
| Country | Link |
|---|---|
| US (2) | US3915986A (pt) |
| JP (2) | JPS609488B2 (pt) |
| AR (1) | AR207248A1 (pt) |
| BE (1) | BE830203A (pt) |
| CA (1) | CA1052798A (pt) |
| CH (1) | CH616157A5 (pt) |
| CY (1) | CY1039A (pt) |
| DD (1) | DD118089A5 (pt) |
| DE (1) | DE2527065C3 (pt) |
| DK (1) | DK135716B (pt) |
| ES (1) | ES438452A1 (pt) |
| FI (1) | FI59247C (pt) |
| FR (1) | FR2275203A1 (pt) |
| GB (1) | GB1464326A (pt) |
| GT (1) | GT198062984A (pt) |
| HK (1) | HK6880A (pt) |
| HU (1) | HU172538B (pt) |
| IE (1) | IE41379B1 (pt) |
| IL (1) | IL47465A (pt) |
| IT (1) | IT1038925B (pt) |
| KE (1) | KE3014A (pt) |
| LU (1) | LU72740A1 (pt) |
| MX (1) | MX3978E (pt) |
| MY (1) | MY8000260A (pt) |
| NL (1) | NL170144C (pt) |
| NO (1) | NO142813C (pt) |
| OA (1) | OA05107A (pt) |
| PH (1) | PH14561A (pt) |
| PL (1) | PL99359B1 (pt) |
| SE (1) | SE420313B (pt) |
| SU (1) | SU572201A3 (pt) |
| YU (1) | YU39322B (pt) |
| ZA (1) | ZA753236B (pt) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1076022B (it) * | 1977-04-20 | 1985-04-22 | Montedison Spa | Benzimidazolcarbammati antielmintici |
| YU40704B (en) * | 1977-05-10 | 1986-04-30 | Chinoin Gyogyszer Es Vegyeszet | Process for obtaininga 5(6)-thiobenzamidazole derivatives |
| IT1107749B (it) * | 1977-10-06 | 1985-11-25 | Montedison Spa | Benzimidazolcarbammato particolarmente attivo contro i parassiti gastroenterici e polmonari |
| US4152522A (en) * | 1978-01-03 | 1979-05-01 | Ethyl Corporation | Process for the preparation of 2-benzimidazole carbamates |
| US4136174A (en) * | 1978-01-18 | 1979-01-23 | E. R. Squibb & Sons, Inc. | Benzimidazolecarbamates and method |
| US4156006A (en) * | 1978-01-09 | 1979-05-22 | E. R. Squibb & Sons, Inc. | Vinyl sulfide derivatives of benzimidazoles |
| DE2840927A1 (de) * | 1978-09-20 | 1980-04-10 | Bayer Ag | 3,4-dihydroisochinoline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DK157547C (da) * | 1978-12-06 | 1990-06-25 | Montedison Spa | Analogifremgangsmaade til fremstilling af 5(6)-substituerede benzimidazolcarbamater. |
| JPS5836122B2 (ja) * | 1979-11-19 | 1983-08-06 | 名古屋高速道路公社 | 回転支保工による橋脚の張出し梁施工法 |
| US4299837A (en) * | 1979-12-05 | 1981-11-10 | Montedison S.P.A. | Anthelmintic benzimidazole-carbamates |
| EP0167491A3 (de) * | 1984-07-06 | 1986-12-30 | Ciba-Geigy Ag | Thiobarbitursäurederivate |
| EP0430885A3 (en) * | 1989-12-01 | 1991-11-06 | Ciba-Geigy Ag | Anthelmintical compounds |
| GB9106278D0 (en) * | 1991-03-25 | 1991-05-08 | Smithkline Beecham Plc | Method of treatment |
| GB9115272D0 (en) * | 1991-07-15 | 1991-08-28 | Pfizer Ltd | Benzimidazole anthelmintics |
| GB9124002D0 (en) * | 1991-11-12 | 1992-01-02 | Pfizer Ltd | Benzimidazole anthelmintic agents |
| GB9205368D0 (en) * | 1992-03-12 | 1992-04-22 | Pfizer Ltd | Benzimidozole anthelmintic agents |
| US5645819A (en) * | 1995-03-13 | 1997-07-08 | Klapow; Lawrence A. | Methods of diagnosing and treating an intestinal and lung roundworm infection |
| US5861142A (en) * | 1996-03-25 | 1999-01-19 | Schick; Mary Pichler | Method for promoting hair, nail, and skin keratinization |
| AU2962397A (en) * | 1996-06-07 | 1998-01-07 | Novartis Ag | Benzazole derivatives |
| ES2344275T3 (es) * | 2005-07-28 | 2010-08-23 | Intervet International Bv | Nuevos (tio) carbamatos de benzimidazol con actividad antiparasitaria y sintesis de ellos. |
| EP2032046B1 (en) * | 2006-06-12 | 2015-11-04 | Smith & Nephew, Inc. | Systems and devices for tibial resection |
| PL2037914T3 (pl) | 2006-06-14 | 2014-04-30 | Intervet Int Bv | Zawiesina zawierająca karbaminian benzoimidazolu i polisorbat |
| WO2016157064A1 (en) | 2015-03-30 | 2016-10-06 | Deva Holding Anonim Sirketi | Stable ricobendazole formulations |
| MA41623A (fr) | 2015-11-26 | 2018-01-09 | Verano Ilac Sanayi Ve Ticaret A S | Composition lyophilisée de composé de benzimidazole |
| EP3178479A1 (en) | 2015-12-08 | 2017-06-14 | Verano Ilac Sanayi Ve Ticaret A.S. | An injectable composition of ricobendazole |
| CN107935939A (zh) * | 2017-11-09 | 2018-04-20 | 华中药业股份有限公司 | 一种阿苯达唑的精制方法 |
| BR102020021181A2 (pt) | 2020-10-16 | 2022-04-26 | Ipanema Industria De Produtos Veterinarios Ltda | Microssuspensão contra parasitas e método para sua obtenção |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE666795A (pt) * | 1964-08-04 | 1966-01-13 | ||
| US3847932A (en) * | 1967-10-26 | 1974-11-12 | Ciba Geigy Ag | Benzimidazole compounds and pesticidal preparations containing them |
| US3840550A (en) * | 1971-05-24 | 1974-10-08 | Ciba Geigy Corp | Certain 6-isothiocyanobenzothiazoles |
-
1974
- 1974-06-19 US US480646A patent/US3915986A/en not_active Expired - Lifetime
-
1975
- 1975-01-01 AR AR259133A patent/AR207248A1/es active
- 1975-05-20 ZA ZA00753236A patent/ZA753236B/xx unknown
- 1975-06-11 ES ES438452A patent/ES438452A1/es not_active Expired
- 1975-06-11 CA CA229,042A patent/CA1052798A/en not_active Expired
- 1975-06-11 IE IE1317/75A patent/IE41379B1/xx not_active IP Right Cessation
- 1975-06-11 GB GB2495575A patent/GB1464326A/en not_active Expired
- 1975-06-11 CY CY1039A patent/CY1039A/xx unknown
- 1975-06-11 IL IL47465A patent/IL47465A/xx unknown
- 1975-06-12 DK DK266175AA patent/DK135716B/da not_active IP Right Cessation
- 1975-06-13 BE BE157297A patent/BE830203A/xx not_active IP Right Cessation
- 1975-06-13 IT IT24364/75A patent/IT1038925B/it active
- 1975-06-14 JP JP50072616A patent/JPS609488B2/ja not_active Expired
- 1975-06-16 LU LU72740A patent/LU72740A1/xx unknown
- 1975-06-17 NL NLAANVRAGE7507190,A patent/NL170144C/xx not_active IP Right Cessation
- 1975-06-17 NO NO752152A patent/NO142813C/no unknown
- 1975-06-17 YU YU1559/75A patent/YU39322B/xx unknown
- 1975-06-17 FI FI751804A patent/FI59247C/fi not_active IP Right Cessation
- 1975-06-17 DD DD186697A patent/DD118089A5/xx unknown
- 1975-06-18 CH CH794275A patent/CH616157A5/de not_active IP Right Cessation
- 1975-06-18 HU HU75SI00001473A patent/HU172538B/hu unknown
- 1975-06-18 DE DE2527065A patent/DE2527065C3/de not_active Expired
- 1975-06-18 FR FR7519035A patent/FR2275203A1/fr active Granted
- 1975-06-18 SU SU7502145903A patent/SU572201A3/ru active
- 1975-06-18 PL PL1975181318A patent/PL99359B1/pl unknown
- 1975-06-18 SE SE7506996A patent/SE420313B/xx not_active IP Right Cessation
- 1975-06-19 MX MX755193U patent/MX3978E/es unknown
- 1975-08-07 US US05/602,704 patent/US3956499A/en not_active Expired - Lifetime
- 1975-09-09 OA OA55607A patent/OA05107A/xx unknown
-
1976
- 1976-10-08 PH PH18989A patent/PH14561A/en unknown
-
1980
- 1980-01-23 KE KE3014A patent/KE3014A/xx unknown
- 1980-02-28 HK HK68/80A patent/HK6880A/xx unknown
- 1980-04-18 GT GT198062984A patent/GT198062984A/es unknown
- 1980-12-30 MY MY260/80A patent/MY8000260A/xx unknown
-
1984
- 1984-10-03 JP JP59209002A patent/JPS60120871A/ja active Granted
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Owner name: SMITHKLINE BECKMAN CORPORATION |
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