CA3186956A1 - Combination therapy for inhalation administration - Google Patents
Combination therapy for inhalation administrationInfo
- Publication number
- CA3186956A1 CA3186956A1 CA3186956A CA3186956A CA3186956A1 CA 3186956 A1 CA3186956 A1 CA 3186956A1 CA 3186956 A CA3186956 A CA 3186956A CA 3186956 A CA3186956 A CA 3186956A CA 3186956 A1 CA3186956 A1 CA 3186956A1
- Authority
- CA
- Canada
- Prior art keywords
- solution composition
- pharmaceutical solution
- composition according
- long
- soft mist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20382710 | 2020-07-31 | ||
EP20382710.0 | 2020-07-31 | ||
PCT/EP2021/071369 WO2022023515A1 (en) | 2020-07-31 | 2021-07-30 | Combination therapy for inhalation administration |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3186956A1 true CA3186956A1 (en) | 2022-02-03 |
Family
ID=72039503
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3186956A Pending CA3186956A1 (en) | 2020-07-31 | 2021-07-30 | Combination therapy for inhalation administration |
Country Status (10)
Country | Link |
---|---|
US (1) | US20230270754A1 (zh) |
EP (1) | EP4188327A1 (zh) |
JP (1) | JP2023540171A (zh) |
KR (1) | KR20230052903A (zh) |
CN (1) | CN115989032A (zh) |
AU (1) | AU2021314977A1 (zh) |
BR (1) | BR112023001689A2 (zh) |
CA (1) | CA3186956A1 (zh) |
MX (1) | MX2023001201A (zh) |
WO (1) | WO2022023515A1 (zh) |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4851317A (en) | 1987-11-04 | 1989-07-25 | E. I. Du Pont De Nemours And Company | Laminar flow toning station having conductive and nonconductive elements therein |
SK282468B6 (sk) | 1995-06-27 | 2002-02-05 | Boehringer Ingelheim Kg | Farmaceutický prostriedok na výrobu inhalovateľných aerosólov bez obsahu hnacieho plynu a jeho použitie |
DE19536902A1 (de) | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
DE19653969A1 (de) | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
SK286694B6 (sk) | 2000-05-22 | 2009-03-05 | Chiesi Farmaceutici S.P.A. | Aerosólový farmaceutický prostriedok |
US20020137764A1 (en) | 2000-10-31 | 2002-09-26 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
JP2004512359A (ja) | 2000-10-31 | 2004-04-22 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 抗コリン作用薬及びコルチコステロイドをベースとする新規医薬組成物 |
US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
EP1879571A1 (de) | 2005-04-23 | 2008-01-23 | Boehringer Ingelheim International GmbH | Arzneimittelkombination für die inhalation enthaltend neben einem anticholinergikum ein betamimetikum und ein steroid |
US20070293460A1 (en) | 2005-10-31 | 2007-12-20 | Richie's Pharmacy And Medical Supply, Incorporated | Delivery of a combination therapy for asthma and chronic obstructive pulmonary disease |
US20070098644A1 (en) | 2005-10-31 | 2007-05-03 | Richie's Pharmacy And Medical Supply, Incorporated | Delivery of a combination therapy for asthma and chronic obstructive pulmonary disease |
DE102006023756A1 (de) | 2006-05-20 | 2007-11-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ethanolhaltige Aerosolformulierung für die Inhalation |
PE20121467A1 (es) | 2009-12-23 | 2012-11-07 | Chiesi Farma Spa | Formulacion de aerosol para la enfermedad pulmonar obstructiva cronica |
CA2785349C (en) | 2009-12-23 | 2018-07-03 | Chiesi Farmaceutici S.P.A. | Combination therapy for copd |
TWI495468B (zh) | 2009-12-23 | 2015-08-11 | Chiesi Farma Spa | 治療慢性阻塞性肺病(copd)之醫藥組成物 |
US20120220557A1 (en) | 2011-02-17 | 2012-08-30 | Chiesi Farmaceutici S.P.A. | Liquid propellant-free formulation comprising an antimuscarinic drug |
EP2934479B1 (en) | 2012-12-21 | 2018-09-19 | Boehringer Ingelheim Vetmedica GmbH | Ciclesonide for the treatment of airway disease in horses |
LT3089735T (lt) | 2013-12-30 | 2018-09-10 | Chiesi Farmaceutici S.P.A. | Glikopironio bromido ir formoterolio derinio stabili suslėgta aerozolinė tirpalo kompozicija |
SI3096737T1 (en) | 2013-12-30 | 2018-07-31 | Chiesi Farmaceutici S.P.A. | Stable aerosol pressure solution containing glycopyrione bromide and formoterol |
US9554992B2 (en) | 2014-06-09 | 2017-01-31 | Chiesi Farmaceutici S.P.A. | Inhalation particles comprising a combination of an anticholinergic, a corticosteroid and a beta-adrenergic |
EP3157522B1 (en) | 2014-06-18 | 2019-09-04 | Boehringer Ingelheim Vetmedica GmbH | Muscarinic antagonists and combinations thereof for the treatment of airway disease in horses |
GB201520862D0 (en) * | 2015-11-25 | 2016-01-13 | Jagotec Ag | Pharmaceutical composition |
US10098837B2 (en) | 2016-07-28 | 2018-10-16 | Chiesi Farmaceutici S.P.A. | Combination therapy for COPD |
-
2021
- 2021-07-30 CN CN202180051794.2A patent/CN115989032A/zh active Pending
- 2021-07-30 BR BR112023001689A patent/BR112023001689A2/pt unknown
- 2021-07-30 WO PCT/EP2021/071369 patent/WO2022023515A1/en active Application Filing
- 2021-07-30 US US18/007,426 patent/US20230270754A1/en active Pending
- 2021-07-30 EP EP21755917.8A patent/EP4188327A1/en active Pending
- 2021-07-30 KR KR1020237006563A patent/KR20230052903A/ko unknown
- 2021-07-30 MX MX2023001201A patent/MX2023001201A/es unknown
- 2021-07-30 CA CA3186956A patent/CA3186956A1/en active Pending
- 2021-07-30 AU AU2021314977A patent/AU2021314977A1/en active Pending
- 2021-07-30 JP JP2023506220A patent/JP2023540171A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
BR112023001689A2 (pt) | 2023-05-02 |
JP2023540171A (ja) | 2023-09-22 |
KR20230052903A (ko) | 2023-04-20 |
CN115989032A (zh) | 2023-04-18 |
AU2021314977A1 (en) | 2023-03-02 |
WO2022023515A1 (en) | 2022-02-03 |
MX2023001201A (es) | 2023-05-03 |
EP4188327A1 (en) | 2023-06-07 |
US20230270754A1 (en) | 2023-08-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11213485B2 (en) | Pharmaceutical solution formulations for pressurized metered dose inhalers | |
EP2201964B1 (en) | Formoterol superfine formulation | |
RU2327450C2 (ru) | Фармацевтические продукты и композиции, содержащие специфические антихолинергические средства, агонисты бета-2 и кортикостероиды | |
US20130074834A1 (en) | Pharmaceutical Combinations | |
EP1415647A1 (en) | "Long-acting beta-2 agonists ultrafine formulations" | |
US20230270754A1 (en) | Combination therapy for inhalation administration | |
JP2014237666A (ja) | アルホルモテロール及びチオトロピウムの組成物及びその使用方法 |