CA1023750A - 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity - Google Patents

5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity

Info

Publication number: CA1023750A
Authority: CA; Canada
Prior art keywords: benzene ring; ring substituted; substituted benzimidazole; carbamate derivatives; anthelmintic activity
Prior art date: 1972-12-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA187,977A

Other languages

English (en)

French (fr)

Inventor

Colin C. Beard

John A. Edwards

John H. Fried

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Syntex USA LLC

Original Assignee

Syntex USA LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-12-29

Filing date

1973-12-12

Publication date

1978-01-03

1973-12-12 Application filed by Syntex USA LLC filed Critical Syntex USA LLC

1978-01-03 Application granted granted Critical

1978-01-03 Publication of CA1023750A publication Critical patent/CA1023750A/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

CA187,977A 1972-12-29 1973-12-12 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity Expired CA1023750A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US31929972A	1972-12-29	1972-12-29
US05/417,968 US3965113A (en)	1972-12-29	1973-11-21	5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity

Publications (1)

Publication Number	Publication Date
CA1023750A true CA1023750A (en)	1978-01-03

Family

ID=26981950

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA187,977A Expired CA1023750A (en)	1972-12-29	1973-12-12	5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity

Country Status (15)

Country	Link
US (1)	US3965113A (de)
JP (1)	JPS4994671A (de)
AR (1)	AR214701A1 (de)
AT (1)	AT332422B (de)
BR (1)	BR7310294D0 (de)
CA (1)	CA1023750A (de)
DE (1)	DE2363348C3 (de)
DK (1)	DK151628C (de)
ES (1)	ES421928A1 (de)
FR (1)	FR2212149B1 (de)
GB (1)	GB1434830A (de)
IE (1)	IE40141B1 (de)
IL (1)	IL43859A (de)
IN (1)	IN138645B (de)
NL (1)	NL7317798A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2425704A1 (de) *	1974-05-28	1975-12-18	Hoechst Ag	Substituierte phenylmercapto-benzimidazole
YU40704B (en)	1977-05-10	1986-04-30	Chinoin Gyogyszer Es Vegyeszet	Process for obtaininga 5(6)-thiobenzamidazole derivatives
US4156006A (en) *	1978-01-09	1979-05-22	E. R. Squibb & Sons, Inc.	Vinyl sulfide derivatives of benzimidazoles
US4136174A (en) *	1978-01-18	1979-01-23	E. R. Squibb & Sons, Inc.	Benzimidazolecarbamates and method
GB1600840A (en)	1978-05-30	1981-10-21	Wellcome Found	Diphenylether derivatives useful as flukicidal agents
EP0028455A1 (de) *	1979-10-12	1981-05-13	Imperial Chemical Industries Plc	5-Phenylselenobenzimidazolderivate, ihre Herstellung und sie enthaltende anthelminthische oder fasziolizide Zusammensetzungen
HU184780B (en) *	1980-09-17	1984-10-29	Chinoin Gyogyszer Es Vegyeszet	Process for producing thiocyanato-benzimidazoles
IL61232A (en) *	1979-10-19	1985-09-29	Chinoin Gyogyszer Es Vegyeszet	Process for the preparation of 2-amino(or alkoxycarbonylamino)-5(6)-thiocyanato(or thiol)benzimidazole derivatives
HU182794B (en) *	1980-03-19	1984-03-28	Chinoin Gyogyszer Es Vegyeszet	Process for producing 5-bracket-6-bracket closed-thiocyanato-benzimidazolyl-alkyl-carbamates and salts
DE3719783A1 (de) *	1987-06-13	1988-12-22	Hoechst Ag	Verfahren zur herstellung von 5-phenylsulfinyl-1h-2-(methoxycarbonylamino)- benzimidazol
GB9900752D0 (en) *	1999-01-15	1999-03-03	Angiogene Pharm Ltd	Benzimidazole vascular damaging agents
US6593466B1 (en)	1999-07-07	2003-07-15	Isis Pharmaceuticals, Inc.	Guanidinium functionalized nucleotides and precursors thereof
CN112094237B (zh) *	2020-11-06	2023-01-20	江苏宝众宝达药业股份有限公司	氟苯咪唑的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2933502A (en) *	1958-02-12	1960-04-19	Du Pont	Benzimidazolone derivatives
US2933504A (en) *	1959-08-10	1960-04-19	Du Pont	Derivatives of polyalkoxycarbonyl imine
US3010968A (en) *	1959-11-25	1961-11-28	Du Pont	Process for manufacture of certain alkyl esters of benzimidazole carbamic acids
BE666795A (de) *	1964-08-04	1966-01-13
US3401171A (en) *	1966-03-11	1968-09-10	Smithkline Corp	2-amidobenzimidazoles
US3480642A (en) *	1967-03-22	1969-11-25	Smithkline Corp	Process for producing 2-carbalkoxyaminobenzimidazoles
CH490010A (de) *	1967-10-26	1970-05-15	Ciba Geigy	Schädlingsbekämpfungsmittel
US3714180A (en) *	1970-08-12	1973-01-30	Squibb & Sons Inc	Sulfonyl benzimidazoles
US3720686A (en) *	1971-04-01	1973-03-13	Squibb & Sons Inc	Mercaptobenzimidazole derivatives
BE793358A (fr) *	1971-12-27	1973-06-27	Hoechst Ag	Nouveaux derives de 2-carbalcoxy-amino-benzimidazole presentantune activite anthelmintique et leur procede de preparation

1973
- 1973-11-21 US US05/417,968 patent/US3965113A/en not_active Expired - Lifetime
- 1973-12-10 IN IN2693/CAL/73A patent/IN138645B/en unknown
- 1973-12-12 CA CA187,977A patent/CA1023750A/en not_active Expired
- 1973-12-13 GB GB5792373A patent/GB1434830A/en not_active Expired
- 1973-12-17 DK DK685373A patent/DK151628C/da not_active IP Right Cessation
- 1973-12-19 IL IL43859A patent/IL43859A/en unknown
- 1973-12-20 DE DE2363348A patent/DE2363348C3/de not_active Expired
- 1973-12-21 AT AT1075073A patent/AT332422B/de not_active IP Right Cessation
- 1973-12-21 IE IE2323/73A patent/IE40141B1/xx unknown
- 1973-12-26 JP JP49004828A patent/JPS4994671A/ja active Pending
- 1973-12-28 BR BR10294/73A patent/BR7310294D0/pt unknown
- 1973-12-28 FR FR7346945A patent/FR2212149B1/fr not_active Expired
- 1973-12-28 AR AR251777A patent/AR214701A1/es active
- 1973-12-28 NL NL7317798A patent/NL7317798A/xx not_active Application Discontinuation
- 1973-12-29 ES ES421928A patent/ES421928A1/es not_active Expired

Also Published As

Publication number	Publication date
FR2212149B1 (de)	1977-07-01
DK151628B (da)	1987-12-21
DE2363348B2 (de)	1980-08-28
ES421928A1 (es)	1976-10-16
GB1434830A (en)	1976-05-05
IE40141B1 (en)	1979-03-28
NL7317798A (de)	1974-07-02
ATA1075073A (de)	1976-01-15
DE2363348A1 (de)	1974-07-18
BR7310294D0 (pt)	1974-09-24
IE40141L (en)	1974-06-29
IN138645B (de)	1976-03-06
AT332422B (de)	1976-09-27
FR2212149A1 (de)	1974-07-26
DK151628C (da)	1988-06-27
DE2363348C3 (de)	1981-04-30
AR214701A1 (es)	1979-07-31
IL43859A0 (en)	1974-03-14
AU6367573A (en)	1975-06-19
JPS4994671A (de)	1974-09-09
US3965113A (en)	1976-06-22
IL43859A (en)	1976-12-31

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