ATE555774T1 - Sprühtrockenverfahren zur herstellung eines trockenen carnitin-pulvers oder -granulats - Google Patents
Sprühtrockenverfahren zur herstellung eines trockenen carnitin-pulvers oder -granulatsInfo
- Publication number
- ATE555774T1 ATE555774T1 AT06776126T AT06776126T ATE555774T1 AT E555774 T1 ATE555774 T1 AT E555774T1 AT 06776126 T AT06776126 T AT 06776126T AT 06776126 T AT06776126 T AT 06776126T AT E555774 T1 ATE555774 T1 AT E555774T1
- Authority
- AT
- Austria
- Prior art keywords
- granule
- producing
- drying process
- spray drying
- carnitine powder
- Prior art date
Links
- 229960004203 carnitine Drugs 0.000 title abstract 3
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title abstract 2
- 239000008187 granular material Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 238000001694 spray drying Methods 0.000 title 1
- -1 carnitine compound Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/007—Carnitine; Butyrobetaine; Crotonobetaine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Animal Husbandry (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Fodder In General (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05014529 | 2005-07-05 | ||
PCT/EP2006/006551 WO2007003425A2 (en) | 2005-07-05 | 2006-07-05 | Spray-drying process for producing a dry carnitine powder or granulate |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE555774T1 true ATE555774T1 (de) | 2012-05-15 |
Family
ID=37562145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06776126T ATE555774T1 (de) | 2005-07-05 | 2006-07-05 | Sprühtrockenverfahren zur herstellung eines trockenen carnitin-pulvers oder -granulats |
Country Status (11)
Country | Link |
---|---|
US (1) | US9084431B2 (de) |
EP (1) | EP1901715B1 (de) |
JP (1) | JP5149172B2 (de) |
KR (1) | KR101327700B1 (de) |
CN (2) | CN101912045B (de) |
AT (1) | ATE555774T1 (de) |
AU (1) | AU2006265280B2 (de) |
BR (1) | BRPI0612611A2 (de) |
CA (1) | CA2611901C (de) |
ES (1) | ES2385046T3 (de) |
WO (1) | WO2007003425A2 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5463526B2 (ja) * | 2008-03-21 | 2014-04-09 | 国立大学法人東京海洋大学 | 健康機能成分を吸着・濃縮した乾燥脱脂穀類糠、該糠から調製した健康機能成分の濃縮物、及びそれらの製造方法 |
EP2335495A1 (de) | 2009-12-11 | 2011-06-22 | Lonza Ltd. | Carnitin-Granulat und Verfahren zu dessen Herstellung |
PL2729015T3 (pl) * | 2011-07-08 | 2019-07-31 | Purac Biochem Bv | Aktywna formulacja do stosowania w produktach paszowych |
WO2014076110A1 (en) | 2012-11-16 | 2014-05-22 | Lonza Ltd. | Methods for decolorizing compositions comprising betaines |
KR101721145B1 (ko) * | 2015-07-29 | 2017-03-29 | 제너럴바이오(주) | L-카르니틴 구연산 마그네슘을 포함하는 배변촉진 겸용 다이어트용 식품 조성물 |
CN106957238A (zh) * | 2017-04-19 | 2017-07-18 | 黄冈华阳药业有限公司 | 一种肉碱的制备工艺 |
JP7240098B2 (ja) * | 2018-01-17 | 2023-03-15 | 昭和産業株式会社 | 飼料原料及び飼料 |
CN111601512B (zh) * | 2019-03-06 | 2023-11-17 | 彭险峰 | γ-季铵基丁酸酯类化合物在制备动物饲料添加剂中的应用 |
CN111838421B (zh) * | 2020-07-27 | 2023-04-21 | 中国科学院天津工业生物技术研究所 | 一种从发酵液中制备5-氨基乙酰丙酸的方法及其应用 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0150688B1 (de) * | 1983-12-28 | 1987-04-22 | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. | Salze von L-Carnitin und Alkanoyl-L-Carnitinen sowie Verfahren zur Herstellung derselben |
FI86889C (fi) | 1984-03-29 | 1992-10-26 | Lonza Ag | Foerfarande foer framstaellning av av l-karnitin pao mikrobiologiskt saett |
US4751182A (en) * | 1984-04-20 | 1988-06-14 | Wisconsin Alumni Research Foundation | Process for preparing L-carnitine from DL-carnitine |
CA2018137C (en) | 1989-06-14 | 2000-01-11 | Thomas Scholl | L-carnitine magnesium citrate |
ATE122540T1 (de) | 1989-07-31 | 1995-06-15 | Univ Georgia Res Found | Karnitindiät für ausgewachsene schweine. |
JPH03120211A (ja) * | 1989-10-04 | 1991-05-22 | Earth Chem Corp Ltd | 粒状カルニチン製剤 |
US5073376A (en) | 1989-12-22 | 1991-12-17 | Lonza Ltd. | Preparations containing l-carnitine |
GB9107628D0 (en) | 1991-04-10 | 1991-05-29 | Moonbrook Limited | Preparation of diagnostic agents |
GB9221329D0 (en) | 1992-10-10 | 1992-11-25 | Delta Biotechnology Ltd | Preparation of further diagnostic agents |
PL180300B1 (pl) | 1993-10-08 | 2001-01-31 | Lonza Ag | wektor zawierajacy taki fragment DNA, a takze mikroorganizmzawierajacy wskazany fragment DNA badz wektor oraz biotechnologiczny sposób wytwarzania L-karnityny PL PL PL PL PL |
JPH0812569A (ja) * | 1994-06-24 | 1996-01-16 | Takeda Chem Ind Ltd | 塩化カルニチン吸着固形物 |
ES2156381T3 (es) * | 1996-05-31 | 2001-06-16 | Sigma Tau Ind Farmaceuti | Sales estables no higroscopicas de l(-)carnitina y alcanoil-l(-)carnitinas, un procedimiento para su preparacion y composiciones solidas, administrables por via oral, que contienen tales sales. |
IT1289974B1 (it) * | 1997-02-25 | 1998-10-19 | Aldo Fassi | Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine |
JP4452341B2 (ja) * | 1999-01-13 | 2010-04-21 | 雪印乳業株式会社 | L−カルニチン剤 |
IT1305308B1 (it) * | 1999-03-26 | 2001-05-04 | Biosint S P A | Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione |
DK1218001T3 (da) * | 1999-09-03 | 2009-04-14 | Sigma Tau Healthscience Spa | Ultrafint L-carnitin, fremgangsmåder til fremstilling deraf, sammensætninger indeholdende det og fremgangsmåder til anvendelse deraf |
ATE295690T1 (de) | 2000-08-29 | 2005-06-15 | Lonza Ag | Verfahren zur herstellung einer granulierbaren mischung und carnitin-magnesium-hydroxycitrat |
CN1203776C (zh) * | 2000-12-07 | 2005-06-01 | 东北制药总厂 | 左旋肉碱饲料添加剂及其制备方法 |
DK1370663T3 (da) | 2001-01-31 | 2007-07-02 | Lonza Ag | Mikrobiologisk metode til fremstilling af L-carnitin |
US7169770B2 (en) | 2001-04-24 | 2007-01-30 | Lonza Ltd. | Method of enhancing reproductive performance in sows |
WO2003009854A1 (en) | 2001-07-20 | 2003-02-06 | Lonza Ag | Lipid lowering composition comprising carnitine and phytosterol |
US20030235646A1 (en) | 2002-03-15 | 2003-12-25 | Lonza Inc. | Method for improving quality of meat by supplementing pig diets and concentrates used therefor |
-
2006
- 2006-07-05 AU AU2006265280A patent/AU2006265280B2/en not_active Ceased
- 2006-07-05 US US11/988,095 patent/US9084431B2/en active Active
- 2006-07-05 ES ES06776126T patent/ES2385046T3/es active Active
- 2006-07-05 KR KR1020087002760A patent/KR101327700B1/ko active IP Right Grant
- 2006-07-05 JP JP2008519856A patent/JP5149172B2/ja active Active
- 2006-07-05 WO PCT/EP2006/006551 patent/WO2007003425A2/en active Application Filing
- 2006-07-05 BR BRPI0612611-1A patent/BRPI0612611A2/pt not_active Application Discontinuation
- 2006-07-05 EP EP06776126A patent/EP1901715B1/de active Active
- 2006-07-05 CN CN2010102628572A patent/CN101912045B/zh active Active
- 2006-07-05 CA CA2611901A patent/CA2611901C/en not_active Expired - Fee Related
- 2006-07-05 AT AT06776126T patent/ATE555774T1/de active
- 2006-07-05 CN CNA2006800242894A patent/CN101212956A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
CN101912045B (zh) | 2013-07-31 |
AU2006265280A1 (en) | 2007-01-11 |
KR20080030650A (ko) | 2008-04-04 |
EP1901715A2 (de) | 2008-03-26 |
EP1901715B1 (de) | 2012-05-02 |
WO2007003425A3 (en) | 2007-03-08 |
US9084431B2 (en) | 2015-07-21 |
US20090082449A1 (en) | 2009-03-26 |
WO2007003425A2 (en) | 2007-01-11 |
AU2006265280B2 (en) | 2011-07-14 |
KR101327700B1 (ko) | 2013-11-11 |
CA2611901C (en) | 2012-12-11 |
JP2009500026A (ja) | 2009-01-08 |
CN101912045A (zh) | 2010-12-15 |
CA2611901A1 (en) | 2007-01-11 |
ES2385046T3 (es) | 2012-07-17 |
BRPI0612611A2 (pt) | 2010-12-07 |
CN101212956A (zh) | 2008-07-02 |
JP5149172B2 (ja) | 2013-02-20 |
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