[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ATE308524T1 - Verfahren zur herstellung von aripiprazole - Google Patents

Verfahren zur herstellung von aripiprazole

Info

Publication number
ATE308524T1
ATE308524T1 AT03780889T AT03780889T ATE308524T1 AT E308524 T1 ATE308524 T1 AT E308524T1 AT 03780889 T AT03780889 T AT 03780889T AT 03780889 T AT03780889 T AT 03780889T AT E308524 T1 ATE308524 T1 AT E308524T1
Authority
AT
Austria
Prior art keywords
producing aripiprazole
aripiprazole
producing
Prior art date
Application number
AT03780889T
Other languages
English (en)
Inventor
Hisayuki Tsujimori
Tatsuya Yamaguchi
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32652780&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE308524(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of ATE308524T1 publication Critical patent/ATE308524T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Quinoline Compounds (AREA)
AT03780889T 2003-01-09 2003-12-18 Verfahren zur herstellung von aripiprazole ATE308524T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003002996 2003-01-09
PCT/JP2003/016256 WO2004063162A1 (en) 2003-01-09 2003-12-18 Process for preparing aripiprazole

Publications (1)

Publication Number Publication Date
ATE308524T1 true ATE308524T1 (de) 2005-11-15

Family

ID=32652780

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03780889T ATE308524T1 (de) 2003-01-09 2003-12-18 Verfahren zur herstellung von aripiprazole

Country Status (20)

Country Link
US (1) US6995264B2 (de)
EP (1) EP1480953B2 (de)
JP (2) JP5797090B2 (de)
KR (1) KR100583667B1 (de)
CN (1) CN1263742C (de)
AR (1) AR042702A1 (de)
AT (1) ATE308524T1 (de)
AU (1) AU2003288755C1 (de)
BR (2) BR0305500A (de)
CA (2) CA2676216A1 (de)
DE (1) DE60302139T3 (de)
DK (1) DK1480953T4 (de)
EG (1) EG23557A (de)
ES (1) ES2250919T5 (de)
HK (1) HK1073110A1 (de)
MX (1) MXPA04002519A (de)
MY (1) MY129831A (de)
SI (1) SI1480953T2 (de)
TW (1) TWI258470B (de)
WO (1) WO2004063162A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2550726A1 (en) * 2003-12-16 2005-06-30 Teva Pharmaceutical Industries Ltd. Methods of preparing aripiprazole crystalline forms
US7714129B2 (en) * 2003-12-16 2010-05-11 Teva Pharmaceutical Industries Ltd. Methods of preparing anhydrous aripiprazole form II
DE202005020539U1 (de) * 2004-02-05 2006-09-28 Teva Pharmaceutical Industries Ltd. Aripiprazol
US7507823B2 (en) 2004-05-06 2009-03-24 Bristol-Myers Squibb Company Process of making aripiprazole particles
EA012180B1 (ru) * 2004-10-08 2009-08-28 Сувен Лайф Сайенсиз Лимитед Способ получения арипипразола и соответствующие промежуточные продукты и их получение
US20060079689A1 (en) * 2004-10-12 2006-04-13 Vladimir Naddaka Processes for preparing and purifying carbostyril compounds such as aripiprazole and 7-(4-halobutoxy)-3,4-dihydro-2(1H)-quinolinones
WO2006053781A1 (en) * 2004-11-18 2006-05-26 Synthon B.V. Process of making crystalline aripiprazole
CN1303068C (zh) * 2005-01-11 2007-03-07 中国人民解放军第二军医大学 一种阿立哌唑的制备方法
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
US20070148100A1 (en) * 2005-09-15 2007-06-28 Elan Pharma International, Limited Nanoparticulate aripiprazole formulations
EP1919453A2 (de) * 2005-12-22 2008-05-14 Teva Pharmaceutical Industries Ltd Verfahren zur reduktion der teilchengrösse von aripiprazol
US20070149782A1 (en) * 2005-12-23 2007-06-28 Michael Brand Methods of preparing a crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1h)-quinolinone and the use thereof in the synthesis of Aripiprazole
EP1845088B1 (de) * 2006-04-10 2009-07-22 Ranbaxy Laboratories Limited Verbesserter Herstellungsprozess für Aripipirazol
WO2008144764A1 (en) 2007-05-21 2008-11-27 Reviva Pharmaceuticals, Inc. Compositions, synthesis, and methods of using quinolinone based atypical antipsychotic agents
WO2009154993A1 (en) 2008-05-27 2009-12-23 Reviva Pharmaceuticals, Inc. Compositions, synthesis, and methods of using piperazine based antipsychotic agents
CN101781246B (zh) * 2009-01-15 2012-02-29 成都康弘药业集团股份有限公司 一种合成阿立哌唑的改进方法
PL2400968T3 (pl) 2009-02-26 2017-04-28 Reviva Pharmaceuticals, Inc. Kompozycje, synteza i sposoby zastosowania pochodnych arylopiperazyny
JOP20200109A1 (ar) 2012-04-23 2017-06-16 Otsuka Pharma Co Ltd مستحضر قابل للحقن
EP3294724A4 (de) * 2015-05-08 2018-11-21 Davuluri, Ramamohan Rao Verbessertes verfahren zur herstellung von aripiprazol mit verringerter partikelgrösse

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130587A (en) * 1978-03-30 1979-10-09 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
DE3034237A1 (de) 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
US5006528A (en) * 1988-10-31 1991-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
JP2608788B2 (ja) * 1988-10-31 1997-05-14 大塚製薬 株式会社 精神分裂病治療剤
JP4060523B2 (ja) 1999-11-24 2008-03-12 大塚製薬株式会社 カルボスチリル誘導体の製造法
AR033485A1 (es) 2001-09-25 2003-12-26 Otsuka Pharma Co Ltd Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma

Also Published As

Publication number Publication date
MY129831A (en) 2007-05-31
DE60302139T3 (de) 2011-02-24
HK1073110A1 (en) 2005-09-23
TW200418840A (en) 2004-10-01
KR20040093655A (ko) 2004-11-06
DE60302139D1 (de) 2005-12-08
CN1263742C (zh) 2006-07-12
CN1590377A (zh) 2005-03-09
KR100583667B1 (ko) 2006-05-26
CA2458929C (en) 2009-09-08
DE60302139T2 (de) 2006-07-20
MXPA04002519A (es) 2005-04-04
JP2014148511A (ja) 2014-08-21
EG23557A (en) 2006-06-05
BR0305500A (pt) 2004-11-03
AU2003288755A1 (en) 2004-08-10
EP1480953B2 (de) 2010-08-18
ES2250919T3 (es) 2006-04-16
SI1480953T2 (sl) 2010-12-31
JP5797090B2 (ja) 2015-10-21
AR042702A1 (es) 2005-06-29
US20040192915A1 (en) 2004-09-30
DK1480953T4 (da) 2010-11-15
EP1480953B1 (de) 2005-11-02
AU2003288755C1 (en) 2015-02-19
EP1480953A1 (de) 2004-12-01
ES2250919T5 (es) 2010-12-03
SI1480953T1 (sl) 2006-04-30
US6995264B2 (en) 2006-02-07
AU2003288755B2 (en) 2005-08-25
CA2676216A1 (en) 2004-07-09
JP2012031203A (ja) 2012-02-16
WO2004063162A1 (en) 2004-07-29
TWI258470B (en) 2006-07-21
BRPI0305500B1 (pt) 2018-01-23
DK1480953T3 (da) 2005-12-19
CA2458929A1 (en) 2004-07-09

Similar Documents

Publication Publication Date Title
ATE408609T1 (de) Verfahren zur herstellung von n-phenylpyrazol-1- carboxamiden
ATE340819T1 (de) Verfahren zur herstellung von polyamiden
ATE479409T1 (de) Verfahren zur herstellung von saugkernen
ATE515500T1 (de) Verfahren zur herstellung von telmisartan
ATE403641T1 (de) Verfahren zur herstellung von o- desmethylvenlafaxin
ATE440888T1 (de) Verfahren zur herstellung von glatiramer
DE602005019848D1 (de) Verfahren zur herstellung von tad- getrocknetem ti
ATA11912002A (de) Verfahren zur herstellung von fälschungssicheren identifikationsmerkmalen
ATE308524T1 (de) Verfahren zur herstellung von aripiprazole
DE602004022134D1 (de) Verfahren zur herstellung von dinitrilen
ATE453619T1 (de) Verfahren zur herstellung von hydroperoxiden
ATE553103T1 (de) Verfahren zur herstellung von (s)-pantoprazol
ATE336478T1 (de) Verfahren zur herstellung von benzophenonen
DE50303611D1 (de) Verfahren zur herstellung von polyisobuten
ATE460414T1 (de) Verfahren zur herstellung von tiotropiumsalzen
ATE402138T1 (de) Verfahren zur herstellung von 2- aminoindanderivaten
ATE549314T1 (de) Verfahren zur herstellung von 4-aminochinazolinen
DE502004004318D1 (de) Verfahren zur herstellung von metall-matrix-verbundwerkstoffen
DE502004007419D1 (de) Verfahren zur Herstellung von Radschüsseln
DE60336173D1 (de) Verfahren zur herstellung von vanadylpyrophosphat-katalysatoren
ATE471941T1 (de) Verfahren zur herstellung von thiazolopyrimidinen
ATE442352T1 (de) Verfahren zur herstellung von modafinil
ATE352573T1 (de) Verfahren zur herstellung von copolymerisaten
ATE382621T1 (de) Verfahren zur herstellung von nevirapin
ATE501282T1 (de) Verfahren zur herstellung von konzentraten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1480953

Country of ref document: EP

UEP Publication of translation of european patent specification

Ref document number: 1480953

Country of ref document: EP