ATE384549T1 - Mikronadel-vorrichtungen und verfahren zur herstellung - Google Patents
Mikronadel-vorrichtungen und verfahren zur herstellungInfo
- Publication number
- ATE384549T1 ATE384549T1 AT02794032T AT02794032T ATE384549T1 AT E384549 T1 ATE384549 T1 AT E384549T1 AT 02794032 T AT02794032 T AT 02794032T AT 02794032 T AT02794032 T AT 02794032T AT E384549 T1 ATE384549 T1 AT E384549T1
- Authority
- AT
- Austria
- Prior art keywords
- microneedle
- microneedles
- cover
- microneedle devices
- methods
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000000758 substrate Substances 0.000 abstract 3
- 238000003491 array Methods 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150274—Manufacture or production processes or steps for blood sampling devices
- A61B5/150282—Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
- A61B5/150572—Pierceable protectors, e.g. shields, caps, sleeves or films, e.g. for hygienic purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
- A61B5/150694—Procedure for removing protection means at the time of piercing
- A61B5/150717—Procedure for removing protection means at the time of piercing manually removed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150977—Arrays of piercing elements for simultaneous piercing
- A61B5/150984—Microneedles or microblades
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Manufacturing & Machinery (AREA)
- Optics & Photonics (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/051,745 US6908453B2 (en) | 2002-01-15 | 2002-01-15 | Microneedle devices and methods of manufacture |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE384549T1 true ATE384549T1 (de) | 2008-02-15 |
Family
ID=21973131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02794032T ATE384549T1 (de) | 2002-01-15 | 2002-11-26 | Mikronadel-vorrichtungen und verfahren zur herstellung |
Country Status (8)
Country | Link |
---|---|
US (2) | US6908453B2 (de) |
EP (1) | EP1465698B1 (de) |
JP (1) | JP4382492B2 (de) |
AT (1) | ATE384549T1 (de) |
AU (1) | AU2002359490A1 (de) |
DE (1) | DE60224842T2 (de) |
IL (1) | IL162554A0 (de) |
WO (1) | WO2003059431A1 (de) |
Families Citing this family (222)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
BR0312671A (pt) * | 2002-07-19 | 2005-04-26 | 3M Innovative Properties Co | Dispositivo de microagulhas, método para utilizar um dispositivo de microagulhas, e, método para aplicar um dispositivo de microagulhas |
US7415299B2 (en) * | 2003-04-18 | 2008-08-19 | The Regents Of The University Of California | Monitoring method and/or apparatus |
CA2536249A1 (en) * | 2003-08-25 | 2005-03-10 | 3M Innovative Properties Company | Delivery of immune response modifier compounds |
BRPI0413867A (pt) * | 2003-08-26 | 2006-10-24 | Alza Corp | dispositivo e método para implantação de célula intradérmica |
US7378451B2 (en) * | 2003-10-17 | 2008-05-27 | 3M Innovative Properties Co | Surfactant composition having stable hydrophilic character |
JP4457229B2 (ja) * | 2003-11-10 | 2010-04-28 | エイジェンシー フォー サイエンス, テクノロジー アンド リサーチ | マイクロニードルおよびマイクロニードルの製造 |
US7753888B2 (en) * | 2003-11-21 | 2010-07-13 | The Regents Of The University Of California | Method and/or apparatus for puncturing a surface for extraction, in situ analysis, and/or substance delivery using microneedles |
US7361182B2 (en) | 2003-12-19 | 2008-04-22 | Lightnix, Inc. | Medical lancet |
JP2007516781A (ja) * | 2003-12-29 | 2007-06-28 | スリーエム イノベイティブ プロパティズ カンパニー | 医療用具および該医療用具を含むキット |
US7150726B2 (en) * | 2004-01-23 | 2006-12-19 | Norfolk Medical | Device for subcutaneous infusion of fluids |
GB0402131D0 (en) | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
WO2005082593A1 (en) * | 2004-02-17 | 2005-09-09 | Avery Dennison Corporation | Method of making microneedles |
US20070191761A1 (en) * | 2004-02-23 | 2007-08-16 | 3M Innovative Properties Company | Method of molding for microneedle arrays |
CN100540086C (zh) * | 2004-03-12 | 2009-09-16 | 新加坡科技研究局 | 用来制造侧开口微型针的方法及模具 |
ES2574802T3 (es) * | 2004-04-12 | 2016-06-22 | Allergan, Inc. | Sistema de inyección multi-sitio |
ES2650188T3 (es) * | 2004-06-10 | 2018-01-17 | 3M Innovative Properties Company | Dispositivo y kit de aplicación de parches |
EP1789127A2 (de) * | 2004-08-05 | 2007-05-30 | Apogee Technology, Inc. | System und verfahren zur arzneiabgabe und mikrofluidische applikationen mit mikronadeln |
US8696619B2 (en) * | 2004-08-10 | 2014-04-15 | Robert P. Schnall | Drug delivery devices |
JPWO2006016647A1 (ja) * | 2004-08-12 | 2008-05-01 | 久光製薬株式会社 | マイクロニードル付き経皮薬物投与装置 |
ES2463818T3 (es) | 2004-08-16 | 2014-05-29 | Functional Microstructures Limited | Dispositivo que se aplicará a una barrera biológica |
AR050608A1 (es) * | 2004-08-19 | 2006-11-08 | Alza Corp | Aparato y metodo para administracion transdermica de factores de crecimiento endotelial vascular |
AU2005306426B2 (en) * | 2004-11-18 | 2011-04-28 | 3M Innovative Properties Company | Masking method for coating a microneedle array |
US9174035B2 (en) | 2004-11-18 | 2015-11-03 | 3M Innovative Properties Company | Microneedle array applicator and retainer |
JP5015787B2 (ja) | 2004-11-18 | 2012-08-29 | スリーエム イノベイティブ プロパティズ カンパニー | マイクロニードルアレイの接触コーティング法 |
CA2587505C (en) | 2004-11-18 | 2013-01-08 | 3M Innovative Properties Company | Low-profile microneedle array applicator |
US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
US20080009800A1 (en) * | 2004-12-02 | 2008-01-10 | Nickel Janice H | Transdermal drug delivery device |
CN102358015A (zh) * | 2004-12-07 | 2012-02-22 | 3M创新有限公司 | 模制微型针的方法 |
CN101076367B (zh) * | 2004-12-10 | 2011-01-26 | 3M创新有限公司 | 医疗设备 |
JP4793806B2 (ja) * | 2005-03-22 | 2011-10-12 | Tti・エルビュー株式会社 | イオントフォレーシス装置 |
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US10035008B2 (en) | 2005-04-07 | 2018-07-31 | 3M Innovative Properties Company | System and method for tool feedback sensing |
US20070270738A1 (en) * | 2005-04-25 | 2007-11-22 | Wu Jeffrey M | Method of treating ACNE with stratum corneum piercing patch |
US7442029B2 (en) | 2005-05-16 | 2008-10-28 | Asml Netherlands B.V. | Imprint lithography |
EP1904158B1 (de) | 2005-06-24 | 2013-07-24 | 3M Innovative Properties Company | Faltbares Pflaster mit Mikronadelnanordnung |
EP2474338B1 (de) * | 2005-06-27 | 2013-07-24 | 3M Innovative Properties Company | Vorrichtung zum Aufbringen einer Mikronadelanordnung |
DE602006016279D1 (de) * | 2005-06-27 | 2010-09-30 | 3M Innovative Properties Co | Mikronadelkartuschenanordnung |
US20070004989A1 (en) * | 2005-06-29 | 2007-01-04 | Parvinder Dhillon | Device for transdermal sampling |
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JP2009522011A (ja) * | 2005-12-30 | 2009-06-11 | Tti・エルビュー株式会社 | 活性物質を生体界面に送達するイオントフォレーシスシステム、装置及び方法 |
US9610459B2 (en) | 2009-07-24 | 2017-04-04 | Emkinetics, Inc. | Cooling systems and methods for conductive coils |
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US8419708B2 (en) * | 2006-02-10 | 2013-04-16 | Hisamitsu Pharmaceuticals Co., Inc. | Transdermal drug administration apparatus having microneedles |
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US7699819B2 (en) | 2006-02-21 | 2010-04-20 | The Hong Kong University Of Science And Technology | Molecular sieve and zeolite microneedles and preparation thereof |
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CA2745339C (en) | 2007-12-24 | 2016-06-28 | The University Of Queensland | Coating method |
WO2009097660A1 (en) * | 2008-02-07 | 2009-08-13 | The University Of Queensland | Patch production |
US20090234322A1 (en) * | 2008-03-12 | 2009-09-17 | Ultradent Products, Inc. | Method of dental tissue injection using an array of micro-needles |
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US8012329B2 (en) | 2008-05-09 | 2011-09-06 | 3M Innovative Properties Company | Dimensional control in electroforms |
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-
2002
- 2002-01-15 US US10/051,745 patent/US6908453B2/en not_active Expired - Fee Related
- 2002-11-26 EP EP02794032A patent/EP1465698B1/de not_active Expired - Lifetime
- 2002-11-26 AU AU2002359490A patent/AU2002359490A1/en not_active Abandoned
- 2002-11-26 DE DE60224842T patent/DE60224842T2/de not_active Expired - Lifetime
- 2002-11-26 IL IL16255402A patent/IL162554A0/xx unknown
- 2002-11-26 AT AT02794032T patent/ATE384549T1/de not_active IP Right Cessation
- 2002-11-26 WO PCT/US2002/037920 patent/WO2003059431A1/en active IP Right Grant
- 2002-11-26 JP JP2003559591A patent/JP4382492B2/ja not_active Expired - Fee Related
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2005
- 2005-04-21 US US11/111,428 patent/US20050187521A1/en not_active Abandoned
Also Published As
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IL162554A0 (en) | 2005-11-20 |
DE60224842D1 (de) | 2008-03-13 |
US20050187521A1 (en) | 2005-08-25 |
EP1465698B1 (de) | 2008-01-23 |
US20030135161A1 (en) | 2003-07-17 |
EP1465698A1 (de) | 2004-10-13 |
US6908453B2 (en) | 2005-06-21 |
JP2005514179A (ja) | 2005-05-19 |
AU2002359490A1 (en) | 2003-07-30 |
WO2003059431A1 (en) | 2003-07-24 |
DE60224842T2 (de) | 2009-01-22 |
JP4382492B2 (ja) | 2009-12-16 |
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