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AT362510B - Verfahren zur herstellung von festen loesungen oder dispersionen von peptidartigen lyserg- saeurederivaten oder deren hydrierten formen - Google Patents

Verfahren zur herstellung von festen loesungen oder dispersionen von peptidartigen lyserg- saeurederivaten oder deren hydrierten formen

Info

Publication number
AT362510B
AT362510B AT767976A AT767976A AT362510B AT 362510 B AT362510 B AT 362510B AT 767976 A AT767976 A AT 767976A AT 767976 A AT767976 A AT 767976A AT 362510 B AT362510 B AT 362510B
Authority
AT
Austria
Prior art keywords
dispersions
peptide
acid derivatives
solid solutions
hydrated forms
Prior art date
Application number
AT767976A
Other languages
German (de)
English (en)
Other versions
ATA767976A (de
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of ATA767976A publication Critical patent/ATA767976A/de
Application granted granted Critical
Publication of AT362510B publication Critical patent/AT362510B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT767976A 1975-10-17 1976-10-15 Verfahren zur herstellung von festen loesungen oder dispersionen von peptidartigen lyserg- saeurederivaten oder deren hydrierten formen AT362510B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2546577A DE2546577B2 (de) 1975-10-17 1975-10-17 Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden

Publications (2)

Publication Number Publication Date
ATA767976A ATA767976A (de) 1980-10-15
AT362510B true AT362510B (de) 1981-05-25

Family

ID=5959411

Family Applications (1)

Application Number Title Priority Date Filing Date
AT767976A AT362510B (de) 1975-10-17 1976-10-15 Verfahren zur herstellung von festen loesungen oder dispersionen von peptidartigen lyserg- saeurederivaten oder deren hydrierten formen

Country Status (28)

Country Link
JP (1) JPS5854122B2 (fr)
AT (1) AT362510B (fr)
AU (1) AU508628B2 (fr)
BE (1) BE847368A (fr)
CA (1) CA1079641A (fr)
CH (1) CH643737A5 (fr)
CS (1) CS199647B2 (fr)
DE (1) DE2546577B2 (fr)
DK (1) DK146194C (fr)
ES (1) ES452420A1 (fr)
FI (1) FI762875A (fr)
FR (1) FR2327764A1 (fr)
GB (1) GB1560406A (fr)
GR (1) GR61268B (fr)
HK (1) HK3183A (fr)
HU (1) HU172533B (fr)
IE (1) IE43778B1 (fr)
IL (1) IL50686A (fr)
MY (1) MY8400063A (fr)
NL (1) NL184558C (fr)
NO (1) NO144468C (fr)
NZ (1) NZ182341A (fr)
PH (1) PH14513A (fr)
PT (1) PT65719B (fr)
SE (1) SE430379B (fr)
SG (1) SG63082G (fr)
SU (1) SU1165223A3 (fr)
ZA (1) ZA766166B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1572226A (en) * 1977-11-03 1980-07-30 Hoechst Uk Ltd Pharmaceutical preparations in solid unit dosage form
US4411882A (en) 1978-12-21 1983-10-25 Sandoz Ltd. Galenical compositions
CH642259A5 (de) * 1978-12-21 1984-04-13 Sandoz Ag Galenische zubereitungen fuer orale applikation von ergotalkaloiden.
FR2454804B1 (fr) * 1979-04-26 1986-11-21 Sanofi Sa Medicament a base de dihydroergotoxine et son procede de preparation
US4366145A (en) * 1981-06-24 1982-12-28 Sandoz, Inc. Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation
US4898729A (en) * 1983-12-09 1990-02-06 Euroceltique, S.A. Treatment of hypertension, compounds and compositions for antihypertension and diuresis
NL194389C (nl) * 1984-06-14 2002-03-04 Novartis Ag Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager.
ES2039287T3 (es) * 1987-01-14 1993-09-16 Ciba-Geigy Ag Procedimiento para la obtencion de un sistema terapeutico peroral para productos activos dificilmente solubles.
FR2610827B1 (fr) * 1987-02-18 1991-09-13 Pf Medicament Comprime de dihydroergotamine (d.h.e.) du type a matrice hydrophile et son procede de fabrication
US5064656A (en) * 1989-11-14 1991-11-12 Dr. Gergely & Co. Uncoated pharmaceutical reaction tablet
DE4401646A1 (de) * 1994-01-21 1995-07-27 Krewel Werke Gmbh Optimal freisetzende Kava-Extrakte
US6524832B1 (en) 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
US6632455B2 (en) 1997-12-22 2003-10-14 Schering Corporation Molecular dispersion composition with enhanced bioavailability
ATE260105T1 (de) * 1997-12-22 2004-03-15 Schering Corp Zubereitung enthaltend eine molekulardispersion mit erhöhter bioverfügbarkeit
US6316462B1 (en) 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
CA2393344C (fr) * 1999-12-03 2009-09-01 Polichem S.A. Procedes permettant la preparation de compositions pharmaceutiques a liberation prolongee d'alcaloides d'ergot presentant une biodisponibilite amelioree et compositions ainsi obtenues
US7771746B2 (en) 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
US7135436B2 (en) 2003-05-05 2006-11-14 J.F. Daley International, Ltd. Solid algicide, preparation and usage in recirculating water
PT1638527E (pt) * 2003-06-27 2007-02-28 Bioprogress Spa Produto compósito obtido por co-trituração de um princípio activo com um copolímero de n-vinil-2-pirrolidona/acetato de vinilo
WO2016198983A1 (fr) 2015-06-09 2016-12-15 Bend Research Inc. Formulations pour obtenir une dissolution rapide d'un médicament à partir de dispersions séchées par pulvérisation dans des capsules

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1175430A (en) * 1966-04-07 1969-12-23 Sandoz Ltd Pharmaceutical Compositions containing Ergot Alkaloids

Also Published As

Publication number Publication date
GB1560406A (en) 1980-02-06
CA1079641A (fr) 1980-06-17
HK3183A (en) 1983-01-20
FI762875A (fr) 1977-04-18
FR2327764A1 (fr) 1977-05-13
NO144468C (no) 1981-09-09
DK454176A (da) 1977-04-18
PT65719B (fr) 1978-06-12
IE43778B1 (en) 1981-05-20
DE2546577A1 (de) 1977-04-21
HU172533B (hu) 1978-09-28
PH14513A (en) 1981-08-24
SU1165223A3 (ru) 1985-06-30
SE430379B (sv) 1983-11-14
MY8400063A (en) 1984-12-31
NZ182341A (en) 1978-09-20
AU1875476A (en) 1978-04-20
IL50686A (en) 1979-05-31
JPS5251014A (en) 1977-04-23
PT65719A (fr) 1976-11-01
DK146194B (da) 1983-07-25
CH643737A5 (en) 1984-06-29
NO144468B (no) 1981-06-01
NL184558B (nl) 1989-04-03
BE847368A (fr) 1977-04-15
IE43778L (en) 1977-04-17
ATA767976A (de) 1980-10-15
GR61268B (en) 1978-10-17
NO763446L (fr) 1977-04-19
SE7611189L (sv) 1977-04-18
NL7611295A (nl) 1977-04-19
JPS5854122B2 (ja) 1983-12-02
CS199647B2 (en) 1980-07-31
ZA766166B (en) 1978-05-30
SG63082G (en) 1983-09-09
ES452420A1 (es) 1978-04-16
DE2546577B2 (de) 1981-04-02
NL184558C (nl) 1989-09-01
DK146194C (da) 1984-01-02
AU508628B2 (en) 1980-03-27
IL50686A0 (en) 1976-12-31
FR2327764B1 (fr) 1979-03-02

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