AR227507A1 - METHOD FOR THE PREPARATION OF 1-PHENYL-3-AZABICICLO (3.1.0) OPTICALLY ACTIVE HEXANS - Google Patents
METHOD FOR THE PREPARATION OF 1-PHENYL-3-AZABICICLO (3.1.0) OPTICALLY ACTIVE HEXANSInfo
- Publication number
- AR227507A1 AR227507A1 AR273764A AR27376478A AR227507A1 AR 227507 A1 AR227507 A1 AR 227507A1 AR 273764 A AR273764 A AR 273764A AR 27376478 A AR27376478 A AR 27376478A AR 227507 A1 AR227507 A1 AR 227507A1
- Authority
- AR
- Argentina
- Prior art keywords
- azabiciclo
- hexans
- phenyl
- preparation
- optically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/40—Unsaturated compounds containing halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/36—Polyhydroxylic alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C61/16—Unsaturated compounds
- C07C61/28—Unsaturated compounds polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72340276A | 1976-09-15 | 1976-09-15 | |
US05/809,341 US4118393A (en) | 1977-06-23 | 1977-06-23 | Phenyl azabicyclohexanones |
US05/809,340 US4118417A (en) | 1977-06-23 | 1977-06-23 | Process for resolving cis-1-substituted phenyl-1,2-cyclopropanedicarboxylic acids |
US05/809,339 US4131611A (en) | 1975-07-31 | 1977-06-23 | Azabicyclohexanes |
Publications (1)
Publication Number | Publication Date |
---|---|
AR227507A1 true AR227507A1 (en) | 1982-11-15 |
Family
ID=27505564
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR268968A AR220684A1 (en) | 1976-09-15 | 1977-08-26 | METHOD FOR THE PREPARATION OF 1-PHENYL-3-AZABICICLO (3.1.0) HEXANS |
AR273764A AR227507A1 (en) | 1976-09-15 | 1978-09-19 | METHOD FOR THE PREPARATION OF 1-PHENYL-3-AZABICICLO (3.1.0) OPTICALLY ACTIVE HEXANS |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR268968A AR220684A1 (en) | 1976-09-15 | 1977-08-26 | METHOD FOR THE PREPARATION OF 1-PHENYL-3-AZABICICLO (3.1.0) HEXANS |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS5337656A (en) |
AR (2) | AR220684A1 (en) |
AT (2) | AT367036B (en) |
AU (1) | AU519620B2 (en) |
BE (1) | BE858683A (en) |
CH (2) | CH637929A5 (en) |
DD (1) | DD133943A5 (en) |
DE (1) | DE2740562A1 (en) |
DK (3) | DK146245C (en) |
FR (1) | FR2375212A1 (en) |
GR (1) | GR72713B (en) |
HU (1) | HU177531B (en) |
NL (1) | NL189041C (en) |
PL (1) | PL115869B1 (en) |
SE (2) | SE435384B (en) |
YU (2) | YU39499B (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4183857A (en) * | 1978-07-06 | 1980-01-15 | Shell Oil Company | 3-Benzyl-3-azabicyclo(3.1.0)hexane-2,4-dione |
IL65843A (en) * | 1977-08-11 | 1986-12-31 | American Cyanamid Co | Pharmaceutical compositions for the treatment of depression containing 3-aza-bicyclo(3.1.0)hexane derivatives and certain novel compounds of this type |
CA1117127A (en) * | 1978-06-27 | 1982-01-26 | Janet A. Day | Derivatives of 3-azabicyclo(3.1.0)hexane and a process for their preparation |
US4225499A (en) * | 1978-07-06 | 1980-09-30 | Shell Oil Company | Process for preparing 3-azabicyclo(3.1.0)hexane-2-carbonitrile |
JPS6332100A (en) * | 1986-07-25 | 1988-02-10 | 東京電力株式会社 | Shield excavator |
JPH0658037B2 (en) * | 1989-09-01 | 1994-08-03 | 日本鋼管株式会社 | Shield excavator |
US6372919B1 (en) | 2001-01-11 | 2002-04-16 | Dov Pharmaceutical, Inc. | (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent |
US6569887B2 (en) | 2001-08-24 | 2003-05-27 | Dov Pharmaceuticals Inc. | (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake |
US20080081834A1 (en) | 2002-07-31 | 2008-04-03 | Lippa Arnold S | Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders |
BRPI0512182A (en) * | 2004-07-22 | 2008-02-19 | Wyeth Corp | Method for treating nervous system conditions and disorders |
BRPI0512186A (en) * | 2004-07-22 | 2008-02-19 | Wyeth Corp | Method for the treatment of disorders and conditions of the nervous system |
US20070043100A1 (en) | 2005-08-16 | 2007-02-22 | Hagen Eric J | Novel polymorphs of azabicyclohexane |
US20070082940A1 (en) | 2005-07-27 | 2007-04-12 | Phil Skolnick | Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders |
US20080045725A1 (en) | 2006-04-28 | 2008-02-21 | Murry Jerry A | Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane |
US8138377B2 (en) | 2006-11-07 | 2012-03-20 | Dov Pharmaceutical, Inc. | Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use |
US9133159B2 (en) | 2007-06-06 | 2015-09-15 | Neurovance, Inc. | 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments |
US20140206740A1 (en) | 2011-07-30 | 2014-07-24 | Neurovance, Inc. | Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1351754A (en) * | 1970-07-02 | 1974-05-01 | Allen & Hanburys Ltd | Indenopyrrole derivatives |
-
1977
- 1977-08-16 GR GR54169A patent/GR72713B/el unknown
- 1977-08-26 AR AR268968A patent/AR220684A1/en active
- 1977-09-01 AU AU28441/77A patent/AU519620B2/en not_active Ceased
- 1977-09-02 NL NLAANVRAGE7709691,A patent/NL189041C/en not_active IP Right Cessation
- 1977-09-08 DE DE19772740562 patent/DE2740562A1/en active Granted
- 1977-09-13 CH CH1118977A patent/CH637929A5/en not_active IP Right Cessation
- 1977-09-13 YU YU2174/77A patent/YU39499B/en unknown
- 1977-09-14 PL PL1977200831A patent/PL115869B1/en unknown
- 1977-09-14 HU HU77AE508A patent/HU177531B/en unknown
- 1977-09-14 DK DK407577A patent/DK146245C/en not_active IP Right Cessation
- 1977-09-14 AT AT0661577A patent/AT367036B/en not_active IP Right Cessation
- 1977-09-14 FR FR7727755A patent/FR2375212A1/en active Granted
- 1977-09-14 BE BE180894A patent/BE858683A/en not_active IP Right Cessation
- 1977-09-15 SE SE7710367A patent/SE435384B/en not_active IP Right Cessation
- 1977-09-15 DD DD77201039A patent/DD133943A5/en unknown
- 1977-09-16 JP JP11064777A patent/JPS5337656A/en active Granted
-
1978
- 1978-09-19 AR AR273764A patent/AR227507A1/en active
-
1980
- 1980-05-30 AT AT0288280A patent/AT367037B/en not_active IP Right Cessation
- 1980-10-16 DK DK438480A patent/DK438480A/en not_active Application Discontinuation
- 1980-10-16 DK DK438580A patent/DK438580A/en not_active Application Discontinuation
-
1982
- 1982-04-05 CH CH209382A patent/CH637931A5/en not_active IP Right Cessation
- 1982-06-03 SE SE8203437A patent/SE452610B/en not_active IP Right Cessation
- 1982-08-23 YU YU1885/82A patent/YU43523B/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX6046E (en) | PROCEDURE FOR THE PREPARATION OF 4,5-DIARIL-2-NITRO-IMIDAZOLES | |
AR227507A1 (en) | METHOD FOR THE PREPARATION OF 1-PHENYL-3-AZABICICLO (3.1.0) OPTICALLY ACTIVE HEXANS | |
IT8024382A0 (en) | METHOD FOR THE PREPARATION OF FLUOROCARBON COMPOUNDS. | |
MX6242E (en) | PROCEDURE FOR THE PREPARATION OF 1,2,3,5, TETRAHIDROIMIDAZOTIENOPIRIMIDIN-2-ONAS | |
AR224997A1 (en) | METHOD FOR PREPARING 5-BENZOIL OR SUBSTITUTED 5-BENZOIL 1,2-DIHYDRO-3H-PIRROLO (1,2-A) PIRROL-1-CARBOXILICOS | |
IT1084225B (en) | PROCESS FOR THE PREPARATION OF ETERI. | |
ES456483A0 (en) | PROCEDURE FOR THE PREPARATION OF STYLBENE COMPOUNDS. | |
ES493650A0 (en) | PROCEDURE FOR THE MANUFACTURE OF 2 (3,4,5-TRIMETOXIFENIL) TIAZOLES, 4,5-DISUBSTITUIDOS | |
IT8019504A0 (en) | PROCEDURE FOR THE SELECTIVE PREPARATION OF ISOSORBITE-5-NITRATE. | |
ES491139A0 (en) | PROCEDURE FOR THE PREPARATION OF 2-AMINO-4-HALOGENO-5- FORMIL-TIAZOLENO. | |
RO75589A (en) | PROCEDURE FOR THE PREPARATION OF 2,6-METHAN-2H-1-BENZOXOXINE | |
MX5685E (en) | PROCEDURE FOR THE PREPARATION OF 4,5-DIARIL-2- (TIO-SUBSTITUTED) -PIRROL | |
MX7052E (en) | PROCEDURE FOR THE PREPARATION OF 2-METOXI-4-AMINO-5-ALKYL SULFONYL-N- (3-BETA-8-AZABICICLO- (3,2,1) OCTIL) -BENZAMIDES | |
IT1091564B (en) | METHOD FOR THE PREPARATION OF 3-DEOXIANTOCIANDINE | |
MX4750E (en) | PROCEDURE FOR THE PREPARATION OF GAMMA-PIRONAS | |
MX4770E (en) | IMPROVED PROCEDURE FOR THE PREPARATION OF TRANS-3,3,5-TRIMETILCICLOHEXIL ETILETER | |
MX5508E (en) | PROCEDURE FOR THE PREPARATION OF 2,3-DIHYDRO-4H-1-BENZOPIRAN-4-ONA O-CARBAMOILOXIMES | |
ES508579A0 (en) | PROCEDURE FOR THE PREPARATION OF ALPHA-HYDROXIACIDES. | |
MX4991E (en) | PROCEDURE FOR THE PREPARATION OF 2,4, DIAMINO-5-TIOBENCILPIRIMIDINAS | |
AR219709A1 (en) | PROCEDURE FOR THE PREPARATION OF 2,3-ALQUILEN-BIS (OXI) BENZAMIDAS SUBSTITUTED | |
IT7925880A0 (en) | PROCEDURE FOR THE PREPARATION OF 1,2,3-TIADIAZOL-5-IL-UREE. | |
MX4834E (en) | PROCESS FOR THE PREPARATION OF 1-BENZOTIAZOLIL IMIDAZOLIDINONAS | |
MX4997E (en) | PROCEDURE FOR THE PREPARATION OF N-2,6, -DICHLORO-FENIL-2-AMINOPIRIMIDINA | |
ES492796A0 (en) | PROCEDURE FOR THE PREPARATION OF 4-OXA-6-AZA-6 (FENIL-ES-PIRO) (2.4) HEPTAN-5,7-DIONAS | |
IT7924894A0 (en) | PROCEDURE FOR THE PREPARATION OF 7, 8DICHLORO-TETRAHYDRO-ISOQUINOLINE. |