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AR066613A1 - Derivados fungicidas de fenil-pirimidinil-amino - Google Patents

Derivados fungicidas de fenil-pirimidinil-amino

Info

Publication number
AR066613A1
AR066613A1 ARP080102095A ARP080102095A AR066613A1 AR 066613 A1 AR066613 A1 AR 066613A1 AR P080102095 A ARP080102095 A AR P080102095A AR P080102095 A ARP080102095 A AR P080102095A AR 066613 A1 AR066613 A1 AR 066613A1
Authority
AR
Argentina
Prior art keywords
substituted
unsubstituted
alkyl
halogen atoms
group
Prior art date
Application number
ARP080102095A
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English (en)
Original Assignee
Bayer Cropscience Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Sa filed Critical Bayer Cropscience Sa
Publication of AR066613A1 publication Critical patent/AR066613A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se refiere a procedimiento de preparacion, a la preparacion de compuestos intermedios, a su utilizacion como agentes fungicidas activos, específicamente en forma de composiciones fungicidas, y a los métodos para el control de hongos fitopatogenos,especialmente de plantas, utilizando estos compuestos o composiciones. Reivindicacion 1: Un derivado de fenil-pirimidinil-amino de formula (1) en donde Q1 independientemente representa un átomo de halogeno, un grupo nitro, un grupo hidroxi, ungrupo ciano, un grupo amino, un grupo sulfanilo, un grupo pentafluoro-?6-sulfanilo , un grupo formilo, un grupo formiloxi, un grupo formilamino, un grupo carbamoilo, un grupo N-hidroxicarbamoílo, un grupo carbamato, un grupo (hidroxiimino)-alquil C1-6, un alquilo C1-8, un tri(alquil C1-8)silil-alquil C1-8 sustituido o no sustituido, un cicloalquilo C1-8 sustituido o no sustituido, tri(alquil C1-6)silil-cicloalquil C1-8 sustituido o no sustituido, un halogenoalquil C1-8 que tiene 1 a 5 átomos dehalogeno, un haIogenocicloalquilo C1-8 que tiene 1 a 5 átomos de halogeno, un alquenilo C2-8, un alquinilo C2-8, un alquenil C2-8-oxi, un alquinil C2-8-oxi, un alquil C1-8-amino, un di-alquil C1-8-amino, un alcoxi C1-8, un halogenoalcoxi C1-8 quetiene 1 a 5 átomos de halogeno, un alquil C1-8-sulfanilo, un halogenoalquil C1-8-sulfanilo que tiene 1 a 5 tomos de halogeno, un alquenil C2-8-oxi, un halogenoalquenil C2-8-oxi que tiene 1a 5 átomos de halogeno, un alquinil C3-8-oxi, unhalogenoalquinil C3-8-oxi que tiene 1 a 5 átomos de halogeno, un alquil C1-8-carbonilo, un halogenoalquil C1-8-carbonilo que tiene 1 a 5 átomos de halogeno, un alquil C1-8-carbamoilo, un di-alquil C1-8-carbamoilo un alquil N-C1-8-oxicarbamoílo, unalcoxi C1-8-carbamoílo, un N-alquil C1-8-alcoxi C1-8-carbamoílo, un alcoxi C1-8-carbonilo, un halogenoalcoxi C1-8-carbonilo que tiene 1 a 5 átomos de halogeno, un alquil C1-8-carboniloxi, un haIogenoalquil C1-8-carboniloxi que tiene 1 a 5 átomos dehalogeno, un alquil C1-8-carbonilamino, un halogenoalquil C1-8-carbonilamino que tiene 1 a 5 átomos de halogeno, un alquil C1-8-aminocarboniloxi, un di-alquil C1-8-aminocarboniloxi, un alquil C1-8-oxicarboniloxi, un alquil C1-8-sulfenilo, unhalogenoalquil C1-8-sulfenilo que tiene 1 a 5 átomos de halogeno, un alquil C1-8-sulfinilo, un halogenoalquil C1-8-sulfinilo que tiene 1 a 5 átomos de halogeno, un alquil C1-8-sulfonilo, un halogenoalquil C1-8-sulfonilo que tiene 1 a 5 átomos dehalogeno, un alquil C1-8-aminosulfamoilo, un dialquil C1-8-aminosulfamoilo, un (alcoxi C1-6-imino)- alquil C1-6, un alquenil (C1-6-oxiimino)-alquil C1-6, un alquinil (C1-6-oxiimino)-aIquil C1-6, un 2-oxopirrolidin-1-ilo, (benciloxiimino)-alquil C1-6sustituido o no sustituido, alcoxialquil C1-8 sustituido o no sustituido, halogenoalcoxialquilo C1-8 sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, benciloxi sustituido o no sustituido, bencilsulfanilo sustituido o no sustituido,bencilamino sustituido o no sustituido, fenoxi sustituido o no sustituido, fenilsulfanilo sustituido o no sustituido o fenilamino sustituido o no sustituido; p representa 0,1, 2, 3, 4 o 5; Ra representa un átomo de hidrogeno, un grupo ciano, ungrupo formilo, un grupo formiloxi, un alcoxi C1-8-carbonilo, un halogenoalcoxi C1-8-carbonilo que tiene 1 a 5 átomos de halogeno, un alquil C1-8-carbonilo, un halogenoalquil C1-8-carbonilo que tiene 1 a 5 átomos de halogeno, un alquil C1-8-sulfonilo, un halogenoalquil C1-8-sulfonilo que tiene 1 a 5 átomos de halogeno, un alquilo C1-8, un cicloalquilo C1-8, un halogenoalquilo C1-8 que tiene 1 a 5 átomos de halogeno, un halogenocicloalquilo C1-8 que tiene 1 a 5 átomos de halogeno, unalquenilo C2-8, un alquinilo C2-8, un alcoxialquilo C1-6, un halogenoalcoxialquilo C1-8 que tiene 1 a 5 átomos de halogeno, Rb y Rc independientemente representan un átomo de hidrogeno, un átomo de halogeno, un ciano, un alquilo C1-8, uncicloalquilo C1-8, un halogenoalquilo C1-8 que tiene 1 a 5 átomos de halogeno, un halogenocicloalquilo C1-8 que tiene 1 a 5 átomos de halogeno; L1 representa un resto piridilo sustituido o no sustituido; Y representa O, S, NRd, CReRf; L2 representaun enlace directo, O, S, NR9, CRhRi; Q2 representa un átomo de hidrogeno, un átomo de halogeno, un grupo nitro, un grupo hidroxi, un grupo ciano, un grupo amino, un grupo sulfanilo, un grupo formilo, un grupo formiloxi, un grupo formilamino, ungrupo carbamoílo, un grupo N-hidroxicarbamoílo, un grupo carbamato, un grupo (hidroxiimino)-alquilo C1-6 sustituido o no sustituido, alquilo C1-8 sustituido o no sustituido, tri(alquil C1-8)sililo-alquilo C1-8 sustituido o no sustituido,cicloalquilo C1-8 sustituido o no sustituido, tri(alquil C1-8)sililo-cicloalquilo C1-8 sustituido o no sustituido, halogenoalquilo C1-8 sustituido o no sustituido que tiene de 1 a 5 átomos de halogeno, halogenocicloalquilo C1-8 sustituido o nosustituido que tiene 1 a 5 átomos de halogeno, un alquenilo C2-8, alquinilo C2-8 sustituido o no sustituido, alquil C1-8 amino sustituido o no sustituido, di-alquil C1-8 amino sustituido o no sustituido, alcoxi C1-6 sustituido o no sustituido,halogenoalcoxi C1-8 sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquenil C2-8 oxi sustituido o no sustituido, alquinil C2-8 oxi sustituido o no sustituido, alquil C1-8-sulfanilo sustituido o no sustituido, halogenoalquil C1-8-sulfanilo sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquenil C2-8-oxi sustituido o no sustituido, halogenoalquenil C2-8 oxi sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquinil C3-8-oxi sustituido o nosustituido, halogenoalquinil C3-8-oxi sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquil C1-8-carbonilo sustituido o no sustituido, halogenoalquil C1-8 carbonilo sustituido o no sustituido que tiene 1 a 5 átomos de halogeno,alquil C1-8-carbamoilo sustituido o no sustituido, di-alquil C1-8-carbamoilo sustituido o no sustituido, alquil N-C1-8-oxicarbamoilo sustituido o no sustituido, alcoxi C1-8-carbamoilo sustituido o no sustituido, N-alquil C1-8-alcoxi C1-8-carbamoilosustituido o no sustituido, alcoxi C1-8-carbonilo sustituido o no sustituido, halogenoalcoxi C1-8-carbonilo sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquil C1-8-carboniloxi sustituido o no sustituido, halogenoalquil C1-8-carboniloxi sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquil C1-8-carbonilamino sustituido o no sustituido, halogenoalquil C1-8-carbonilamino sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquil C1-8-aminocarboniloxi sustituido o no sustituido, dialquil C1-8-aminocarboniloxi sustituido o no sustituido, alquil C1-8-oxicarboniloxi sustituido o no sustituido, alquil C1-8-sulfenilo sustituido o no sustituido, halogenoalquil C1-8-sulfenilo sustituidoo no sustituido que tiene 1 a 5 átomos de halogeno, alquil C1-8-sulfinilo sustituido o no sustituido, halogenoalquil C1-8-sulfinilo sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquil C1-8-sulfonilo sustituido o no sustituido,halogenoalquil C1-8-sulfonilo sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquil C1-8-aminosulfamoilo sustituido o no sustituido, dialquil C1-8-aminosulfamoilo sustituido o no sustituido, (alcoxi C1-6-imino)-alquil C1-6 sustituidoo no sustituido, alquenil (C1-6-oxiimino)-alquil C1-6 sustituido o no sustituido, (alquinil C1-6-oxiimino)-alquilo C1-6 sustituido o no sustituido, (2-oxopirrolidin-1-il) alquilo C1-8, (2-oxopirrolidin-1-il) halogenoalquil C1-8 que tiene 1 a 5átomos de halogeno, (2-oxopiperidin-1-il) alquil C1-8, (2-oxopiperidin-1-il) halogenoalquil C1-8 que tiene 1 a 5 átomos de halogeno, (2-oxoazepan-1-il) alquil C1-8, (2-oxoazepan-1-il) halogenoalquil C1-8 que tiene 1 a 5 átomos de halogeno,(benciloxiimino)-alquil C1-6 sustituido o no sustituido, alcoxialquil C1-8 sustituido o no sustituido, halogenoalcoxi C1-8 alquil sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, benciloxi sustituido o no sustituido, bencilsulfanilosustituido o no sustituido, bencilamino sustituido o no sustituido, fenoxi sustituido o no sustituido, fenilsulfanilo sustituido o no sustituido, fenilamino sustituido o no sustituido, un heterociclo sustituido o no sustituido de 4, 5, 6 o 7elementos que comprende hasta 4 heteroátomos seleccionados en la lista consistente en N, O, S; L2 y Q2 puede formar conjuntamente un heterociclo de 4, 5, 6 o 7 elementos sustituido o no sustituido, que comprende hasta 4 heteroátomos seleccionados enla lista consistente en N, O, S; Rd, Re, Rf, Rg, Rh y Ri representan independientemente un átomo de hidrogeno, un átomo de halogeno, un grupo nitro, un grupo ciano, un grupo hidroxi, un grupo amino, un grupo sulfanilo, un grupo formilo, un grupoformiloxi, un grupo formilamino, un grupo carbamoilo, un grupo N-hidroxicarbamoílo, un grupo carbamato, un grupo (hidroxiimino)-alquilo C1-6 sustituido o no sustituido, alquilo C1-8 sustituido o no sustituido, tri(alquil C1-8)sililo, tri( alquil C1-8)sililo-alquilo C1-8 sustituido o no sustituido, cicloalquilo C1-8 sustituido o no sustituido, tri(alquil C1-8)silil-cicloalquilo C1-8 sustituido o no sustituido, halogenoalquilo C18 sustituido o no sustituido que tiene de 1 a 5 átomos de halogeno,halogenocicloalquilo C1-8 sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, un alquenilo C2-8, alquinilo C2-8 sustituido o no sustituido, alquil C1-8 amino sustituido o no sustituido, di-alquil C1-8 amino sustituido o no sustituido,alcoxi C1-8 sustituido o no sustituido, halogenoalcoxi C1-8 sustituido o no sustituido que tiene 1 a 5 tomos de halogeno, alquenil C2-8-oxi sustituido o no sustituido, alquinil C2-8-oxi sustituido o no sustituido, alquil C1-8-sulfanilo sustituido ono sustituido, halogenoalquil C1-8-sulfanilo sustituido o no sustituido que tiene 1 a 5 átomos de halogeno, alquenil C2-8-oxi sustituido o no sustituido, halogenoalquenil C2-8-oxi sustituido o no sustituido que tiene 1
ARP080102095A 2007-05-16 2008-05-16 Derivados fungicidas de fenil-pirimidinil-amino AR066613A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07356067 2007-05-16

Publications (1)

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AR066613A1 true AR066613A1 (es) 2009-09-02

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US (1) US20100137309A1 (es)
EP (1) EP2155713A1 (es)
JP (1) JP2010526856A (es)
KR (1) KR20100017181A (es)
CN (1) CN101687839A (es)
AR (1) AR066613A1 (es)
AU (1) AU2008249959A1 (es)
BR (1) BRPI0809755A2 (es)
CA (1) CA2683074A1 (es)
CL (1) CL2008001460A1 (es)
CO (1) CO6251205A2 (es)
IL (1) IL201319A0 (es)
MX (1) MX2009012217A (es)
RU (1) RU2459819C2 (es)
TW (1) TW200901880A (es)
WO (1) WO2008138992A1 (es)
ZA (1) ZA200907389B (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110218188A1 (en) * 2008-11-13 2011-09-08 Christian Beier Substituted (pyridyl)-azinylamine derivatives as fungicides

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* Cited by examiner, † Cited by third party
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ES2054867T3 (es) * 1987-09-28 1994-08-16 Ciba Geigy Ag Plaguicidas y pesticidas.
JPH08503971A (ja) * 1993-10-01 1996-04-30 チバ−ガイギー アクチェンゲゼルシャフト ピリミジンアミン誘導体及びその調製のための方法
US5728708A (en) * 1993-10-01 1998-03-17 Novartis Corporation Pharmacologically active pyridine derivatives and processes for the preparation thereof
US5705502A (en) * 1993-10-01 1998-01-06 Novartis Corporation Pharmacologically active pyrimidineamine derivatives and processes for the preparation thereof
GB0014022D0 (en) * 2000-06-08 2000-08-02 Novartis Ag Organic compounds
DK1330452T3 (da) * 2000-09-20 2009-03-16 Ortho Mcneil Janssen Pharm Pyrazinderivater som modulatorer af tyrosinkinaser
GB0100102D0 (en) * 2001-01-03 2001-02-14 Syngenta Participations Ag Organic compounds
GB0123589D0 (en) * 2001-10-01 2001-11-21 Syngenta Participations Ag Organic compounds
KR20040048920A (ko) * 2001-11-01 2004-06-10 얀센 파마슈티카 엔.브이. 글리코겐 신타아제 키나제 3-베타 저해제(ｇｓｋ저해제)로서의 헤테로아릴 아민
GB0129476D0 (en) * 2001-12-10 2002-01-30 Syngenta Participations Ag Organic compounds
GB0307268D0 (en) * 2003-03-28 2003-05-07 Syngenta Ltd Organic compounds
US20110218188A1 (en) * 2008-11-13 2011-09-08 Christian Beier Substituted (pyridyl)-azinylamine derivatives as fungicides

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IL201319A0 (en) 2010-05-31
CN101687839A (zh) 2010-03-31
KR20100017181A (ko) 2010-02-16
CL2008001460A1 (es) 2008-11-21
JP2010526856A (ja) 2010-08-05
BRPI0809755A2 (pt) 2014-09-23
RU2009146565A (ru) 2011-06-27
TW200901880A (en) 2009-01-16
CO6251205A2 (es) 2011-02-21
US20100137309A1 (en) 2010-06-03
EP2155713A1 (en) 2010-02-24
AU2008249959A1 (en) 2008-11-20
ZA200907389B (en) 2010-07-28
WO2008138992A1 (en) 2008-11-20
CA2683074A1 (en) 2008-11-20
RU2459819C2 (ru) 2012-08-27
MX2009012217A (es) 2009-12-01

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