AR065580A1 - Mejoras en composiciones medicinales o relativas a las mismas - Google Patents
Mejoras en composiciones medicinales o relativas a las mismasInfo
- Publication number
- AR065580A1 AR065580A1 ARP080100881A ARP080100881A AR065580A1 AR 065580 A1 AR065580 A1 AR 065580A1 AR P080100881 A ARP080100881 A AR P080100881A AR P080100881 A ARP080100881 A AR P080100881A AR 065580 A1 AR065580 A1 AR 065580A1
- Authority
- AR
- Argentina
- Prior art keywords
- buprenorphine
- naltrexone
- same
- dosage form
- medicinal compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 abstract 4
- 229960001736 buprenorphine Drugs 0.000 abstract 4
- DQCKKXVULJGBQN-XFWGSAIBSA-N naltrexone Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=O)O)CC1)O)CC1CC1 DQCKKXVULJGBQN-XFWGSAIBSA-N 0.000 abstract 3
- 229960003086 naltrexone Drugs 0.000 abstract 3
- 230000000202 analgesic effect Effects 0.000 abstract 2
- 210000004207 dermis Anatomy 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 239000006201 parenteral dosage form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Una composicion analgésica, en una forma de dosificacion parenteral unitaria o en una forma de dosificacion unitaria adecuada para una administracion por la dermis o mucosa, donde dicha composicion comprende buprenorfina y una cantidad de naltrexonatal que la relacion en peso de buprenorfina a naltrexona administrada o que alcanzo el plasma de un paciente se encuentra en el rango entre 100: 1 y 5000:1. La accion analgésica de buprenorfina es potenciada por la baja dosis de naltrexona. Unmétodo de tratamiento del dolor y el uso de buprenorfina y naltrexona para la elaboracion de un medicamento.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0703966A GB2447014A (en) | 2007-03-01 | 2007-03-01 | Analgesic composition comprising a specific ratio of buprenorphine and naltrexone |
Publications (1)
Publication Number | Publication Date |
---|---|
AR065580A1 true AR065580A1 (es) | 2009-06-17 |
Family
ID=37965733
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080100881A AR065580A1 (es) | 2007-03-01 | 2008-02-29 | Mejoras en composiciones medicinales o relativas a las mismas |
Country Status (21)
Country | Link |
---|---|
US (1) | US8912211B2 (es) |
EP (1) | EP2125019B1 (es) |
JP (1) | JP5577101B2 (es) |
KR (1) | KR20090115861A (es) |
CN (1) | CN101622014A (es) |
AR (1) | AR065580A1 (es) |
AU (1) | AU2008220620A1 (es) |
BR (1) | BRPI0807902A2 (es) |
CA (1) | CA2678481C (es) |
CL (1) | CL2008000608A1 (es) |
DK (1) | DK2125019T3 (es) |
ES (1) | ES2475734T3 (es) |
GB (1) | GB2447014A (es) |
HR (1) | HRP20140592T1 (es) |
MX (1) | MX2009009132A (es) |
PE (1) | PE20081799A1 (es) |
PL (1) | PL2125019T3 (es) |
PT (1) | PT2125019E (es) |
TW (1) | TW200836737A (es) |
WO (1) | WO2008104735A1 (es) |
ZA (1) | ZA200905689B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9205081B2 (en) | 2010-04-29 | 2015-12-08 | Allodynic Therapeutics, Llc | Combinations of opiod/TLR4 antagonist and a cyclooxygenase (COX) inhibitor for use in the treatment of pain |
US9095548B2 (en) | 2010-04-29 | 2015-08-04 | Allodynic Therapeutics, Llc | Combinations of opioid/TLR4 antagonists and acetyl-para-aminophenol (APAP) for use in the treatment of pain |
MX2013003354A (es) * | 2010-09-21 | 2013-06-24 | Purdue Pharma Lp | Analogos de buprenorfina. |
JP2016512561A (ja) * | 2013-03-13 | 2016-04-28 | アロディニック セラピューティクス リミテッド ライアビリティ カンパニー | オピオイド/トール様受容体4アンタゴニスト、そのデキストロエナンチオマーを含む、痛みを軽減するための組成物、及びそのための使用方法 |
ES2703623T3 (es) * | 2013-06-28 | 2019-03-11 | Purdue Pharma Lp | Antagonistas opioides para uso en el tratamiento de una arritmia inducida por analgésicos opioides |
US9839611B2 (en) | 2013-09-10 | 2017-12-12 | Insys Development Company, Inc. | Sublingual buprenorphine spray |
US9867818B2 (en) | 2013-09-10 | 2018-01-16 | Insys Development Company, Inc. | Sublingual buprenorphine spray |
DK3043777T3 (da) | 2013-09-10 | 2020-07-20 | Fresh Cut Dev Llc | Sublingual buprenorphinspray |
US9918981B2 (en) | 2013-09-10 | 2018-03-20 | Insys Development Company, Inc. | Liquid buprenorphine formulations |
US10722510B2 (en) | 2014-07-08 | 2020-07-28 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
WO2016007245A1 (en) | 2014-07-08 | 2016-01-14 | Insys Pharma, Inc. | Sublingual naloxone spray |
US10617686B2 (en) | 2014-07-08 | 2020-04-14 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
US20180147201A1 (en) | 2016-10-31 | 2018-05-31 | Allodynic Therapeutics, Llc | Combinations of opioid/tlr4 antagonists and acetaminophen for use in the treatment of emotional pain and insomnia |
US11752143B2 (en) | 2020-12-31 | 2023-09-12 | Soin Therapeutics Llc | Methods of using low dose naltrexone to treat chronic pain |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US572149A (en) * | 1896-12-01 | Tobacco-cutting machine | ||
GB8430346D0 (en) | 1984-11-30 | 1985-01-09 | Reckitt & Colmann Prod Ltd | Analgesic compositions |
GB8728294D0 (en) | 1987-12-03 | 1988-01-06 | Reckitt & Colmann Prod Ltd | Treatment compositions |
US5272149A (en) * | 1992-05-05 | 1993-12-21 | Stalling Reginald W | Symptom controlled receptor substitution for addiction withdrawl |
US6096756A (en) * | 1992-09-21 | 2000-08-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
PL341309A1 (en) * | 1997-12-22 | 2001-04-09 | Euro Celtique | Method of preventing overdosage of opioidic preparations |
AR031682A1 (es) | 1999-11-19 | 2003-10-01 | Reckitt Benckiser Helthcare Uk | Composiciones farmaceuticas |
SI2517710T1 (sl) * | 2000-02-08 | 2015-07-31 | Euro-Celtique S.A. | Oralne formulacije opioidnih agonistov, varne pred zlorabo |
US20050191340A1 (en) * | 2002-08-09 | 2005-09-01 | Gruenenthal Gmbh | Opioid-receptor antagonists in transdermal systems having buprenorphine |
-
2007
- 2007-03-01 GB GB0703966A patent/GB2447014A/en not_active Withdrawn
-
2008
- 2008-02-15 JP JP2009551253A patent/JP5577101B2/ja not_active Expired - Fee Related
- 2008-02-15 US US12/529,173 patent/US8912211B2/en not_active Expired - Fee Related
- 2008-02-15 BR BRPI0807902-1A2A patent/BRPI0807902A2/pt not_active IP Right Cessation
- 2008-02-15 CA CA2678481A patent/CA2678481C/en not_active Expired - Fee Related
- 2008-02-15 DK DK08709412.4T patent/DK2125019T3/da active
- 2008-02-15 PL PL08709412T patent/PL2125019T3/pl unknown
- 2008-02-15 PT PT87094124T patent/PT2125019E/pt unknown
- 2008-02-15 EP EP08709412.4A patent/EP2125019B1/en not_active Not-in-force
- 2008-02-15 CN CN200880006857A patent/CN101622014A/zh active Pending
- 2008-02-15 KR KR1020097018309A patent/KR20090115861A/ko active Search and Examination
- 2008-02-15 WO PCT/GB2008/000521 patent/WO2008104735A1/en active Application Filing
- 2008-02-15 ES ES08709412.4T patent/ES2475734T3/es active Active
- 2008-02-15 MX MX2009009132A patent/MX2009009132A/es active IP Right Grant
- 2008-02-15 AU AU2008220620A patent/AU2008220620A1/en not_active Abandoned
- 2008-02-27 TW TW097106771A patent/TW200836737A/zh unknown
- 2008-02-28 CL CL200800608A patent/CL2008000608A1/es unknown
- 2008-02-29 PE PE2008000410A patent/PE20081799A1/es not_active Application Discontinuation
- 2008-02-29 AR ARP080100881A patent/AR065580A1/es unknown
-
2009
- 2009-08-17 ZA ZA2009/05689A patent/ZA200905689B/en unknown
-
2014
- 2014-06-24 HR HRP20140592AT patent/HRP20140592T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
US8912211B2 (en) | 2014-12-16 |
KR20090115861A (ko) | 2009-11-09 |
GB0703966D0 (en) | 2007-04-11 |
EP2125019A1 (en) | 2009-12-02 |
AU2008220620A1 (en) | 2008-09-04 |
PL2125019T3 (pl) | 2014-08-29 |
CN101622014A (zh) | 2010-01-06 |
DK2125019T3 (da) | 2014-06-30 |
JP2010520183A (ja) | 2010-06-10 |
TW200836737A (en) | 2008-09-16 |
EP2125019B1 (en) | 2014-04-09 |
CA2678481A1 (en) | 2008-09-04 |
JP5577101B2 (ja) | 2014-08-20 |
PT2125019E (pt) | 2014-07-11 |
CL2008000608A1 (es) | 2008-10-03 |
MX2009009132A (es) | 2009-09-03 |
WO2008104735A1 (en) | 2008-09-04 |
HRP20140592T1 (hr) | 2014-09-12 |
ZA200905689B (en) | 2010-10-27 |
BRPI0807902A2 (pt) | 2014-06-17 |
ES2475734T3 (es) | 2014-07-11 |
GB2447014A (en) | 2008-09-03 |
CA2678481C (en) | 2014-11-18 |
US20100120812A1 (en) | 2010-05-13 |
PE20081799A1 (es) | 2008-12-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR065580A1 (es) | Mejoras en composiciones medicinales o relativas a las mismas | |
AR065579A1 (es) | Mejoras en composiciones medicinales o relativas a las mismas | |
AR031682A1 (es) | Composiciones farmaceuticas | |
AR075735A1 (es) | Composiciones farmaceuticas de liberacion inmediata que comprenden oxicodona y naloxona. uso | |
NZ605887A (en) | Pharmaceutical dosage form comprising 6’-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4’,9’-dihydro-3’h-spiro[cyclohexane-1,1’-pyrano[3,4,b]indol]-4-amine for the treatment of neuropathic pain | |
AR065582A1 (es) | Mejoras en composiciones medicinales o relativas a las mismas | |
PE20170302A1 (es) | Uso de pridopidina en dosis altas para el tratamiento de enfermedad de huntington | |
BRPI0513200A (pt) | uso de um anticorpo anti-igf-1r na preparação de um medicamento para tratamento combinado para malignidades não-hematológicas | |
AR065581A1 (es) | Mejoras en composiciones medicinales o relativas a las mismas | |
NZ587202A (en) | Methods for measuring a patient response upon administration of a drug and compositions thereof | |
JP2010520186A5 (es) | ||
AR070047A1 (es) | Tratamientos terapeuticos contra el cancer. composicion que comprende un inhibidor de hedgehog. | |
CO6220962A2 (es) | Usos terapeuticos novedosos de 1-[2(2,4-dimetilfenilsulfanil)fenil]-piperazina | |
AR065731A1 (es) | Composiciones farmaceuticas que contienen 2-[6-(3-amino-pipenidin-1-il)-3-metil-2,4-dioxo-3,4-dihidro-2h-primidin-1-il metil]-4-fluoro-benzonitrilo. uso. metodo de tratamiento, administracion semanal de inhibidores de la dipeptidilpeptidasa. | |
WO2012007159A3 (en) | Novel gastro-retentive dosage forms | |
AR063782A1 (es) | Parche y metodo transdermico para emesis | |
HRP20192189T1 (hr) | Doziranja i terapijske primjene l-4-klorokinurenina | |
AR084093A1 (es) | Metodo para tratar los atracones o la ingesta compulsiva de alimentos; uso de buproprion y naltrexona para preparar un medicamento para dichos metodos, y composicion farmaceutica | |
AR065139A1 (es) | Medicamento para el tratamiento de la endometriosis | |
BRPI0409380A (pt) | composições farmacêuticas | |
JP2010520184A5 (es) | ||
BR112014004339A2 (pt) | suspensão oral | |
AR075866A1 (es) | Una dosis de ave5026 para el tratamiento de tromboembolismo venoso en pacientes con deterioro renal severo. uso. composicion farmaceutica. | |
RU2013105513A (ru) | Производные 1-аминоалкилциклогексана для лечения воспалительных заболеваний кожи | |
AR048318A1 (es) | Formulaciones de matriz orales que comprenden licarbazepina |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |