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AR049732A1 - Proceso para enriquecer una poblacion de celulas de esperma - Google Patents

Proceso para enriquecer una poblacion de celulas de esperma

Info

Publication number
AR049732A1
AR049732A1 ARP050103054A ARP050103054A AR049732A1 AR 049732 A1 AR049732 A1 AR 049732A1 AR P050103054 A ARP050103054 A AR P050103054A AR P050103054 A ARP050103054 A AR P050103054A AR 049732 A1 AR049732 A1 AR 049732A1
Authority
AR
Argentina
Prior art keywords
dispersion
sperm cells
sperm
subpopulation
cells
Prior art date
Application number
ARP050103054A
Other languages
English (en)
Inventor
Jeffrey A Graham
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/092,338 external-priority patent/US7892725B2/en
Priority claimed from US11/092,509 external-priority patent/US7998700B2/en
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of AR049732A1 publication Critical patent/AR049732A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/52—Sperm; Prostate; Seminal fluid; Leydig cells of testes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0608—Germ cells
    • C12N5/0612—Germ cells sorting of gametes, e.g. according to sex or motility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Signal Processing (AREA)
  • Dispersion Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Procesos para enriquecer selectivamente una poblacion de células de esperma viables respecto de una característica sin separar físicamente las células. Las células contenidas en esta poblacion enriquecida se benefician con la ventaja de no ser sometidas a un proceso de clasificacion. También se describen procesos para inseminar un mamífero hembra y procesos para formar una dispersion de esperma utilizando los procesos para enriquecer selectivamente una poblacion de células de esperma viables. Reivindicacion 1: Un proceso para reducir selectivamente la capacidad de una subpoblacion de células de esperma en una dispersion de células de esperma de fertilizar un huevo, donde el proceso comprende: formar una dispersion de células de esperma marcadas en un líquido, donde el líquido comprende un agente químico o que tiene una temperatura que induce la inmotilidad del esperma, donde la presencia, la ausencia o la cantidad de la marca asociada con una célula de esperma indica una característica genética, proteomica o funcional de una subpoblacion de células de esperma en la dispersion; inspeccionar opticamente la dispersion para identificar células de esperma individuales como miembros de la subpoblacion; determinar la posicion de los miembros de la subpoblacion en la dispersion; y administrar una dosis de energía en distintas posiciones dentro de la dispersion para disminuir selectivamente la capacidad de los miembros de la subpoblacion de fertilizar un huevo, sin afectar de forma similar las células de esperma en otras posiciones en la dispersion.
ARP050103054A 2004-07-22 2005-07-22 Proceso para enriquecer una poblacion de celulas de esperma AR049732A1 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US59027004P 2004-07-22 2004-07-22
US59076904P 2004-07-23 2004-07-23
US61417804P 2004-09-29 2004-09-29
US61844004P 2004-10-13 2004-10-13
US11/092,338 US7892725B2 (en) 2004-03-29 2005-03-29 Process for storing a sperm dispersion
US11/092,509 US7998700B2 (en) 2004-03-29 2005-03-29 Use of a composition which regulates oxidation/reduction reactions intracellularly and/or extracellulary in a staining or sorting process
US11/092,313 US7838210B2 (en) 2004-03-29 2005-03-29 Sperm suspensions for sorting into X or Y chromosome-bearing enriched populations

Publications (1)

Publication Number Publication Date
AR049732A1 true AR049732A1 (es) 2006-08-30

Family

ID=35219522

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050103054A AR049732A1 (es) 2004-07-22 2005-07-22 Proceso para enriquecer una poblacion de celulas de esperma

Country Status (9)

Country Link
US (1) US7833147B2 (es)
EP (2) EP2269617B1 (es)
JP (1) JP2008507287A (es)
AR (1) AR049732A1 (es)
AU (1) AU2005266930B2 (es)
BR (1) BRPI0513685A (es)
CA (1) CA2574499C (es)
MX (1) MX2007000888A (es)
WO (1) WO2006012597A2 (es)

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DK2258170T3 (en) 2000-05-09 2017-10-16 Xy Llc X-chromosome-bearing and Y-chromosome-bearing populations of high purity spermatozoa
CA2468772C (en) 2000-11-29 2013-10-29 George E. Seidel System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
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JP2005535346A (ja) 2002-08-15 2005-11-24 エックスワイ，インコーポレイテッド 高分解能フローサイトメーター
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
JP4614947B2 (ja) 2003-03-28 2011-01-19 イングラン・リミテッド・ライアビリティ・カンパニー 粒子を仕分けるためおよび性別で仕分けられた動物の精子を提供するための装置、および方法
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
BRPI0509488A (pt) 2004-03-29 2007-09-11 Monsanto Technology Llc suspensões de esperma para seleção de populações enriquecidas carregando cromossomo x ou y
AR049732A1 (es) 2004-07-22 2006-08-30 Monsanto Co Proceso para enriquecer una poblacion de celulas de esperma
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