AP3286A - Glucagon analogues - Google Patents
Glucagon analoguesInfo
- Publication number
- AP3286A AP3286A AP2013006669A AP2013006669A AP3286A AP 3286 A AP3286 A AP 3286A AP 2013006669 A AP2013006669 A AP 2013006669A AP 2013006669 A AP2013006669 A AP 2013006669A AP 3286 A AP3286 A AP 3286A
- Authority
- AP
- ARIPO
- Prior art keywords
- glucagon analogues
- glucagon
- analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201000550 | 2010-06-23 | ||
US35862310P | 2010-06-25 | 2010-06-25 | |
PCT/DK2011/000067 WO2011160630A2 (en) | 2010-06-23 | 2011-06-23 | Glucagon analogues |
Publications (2)
Publication Number | Publication Date |
---|---|
AP2013006669A0 AP2013006669A0 (en) | 2013-01-31 |
AP3286A true AP3286A (en) | 2015-05-31 |
Family
ID=44630045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2013006669A AP3286A (en) | 2010-06-23 | 2011-06-23 | Glucagon analogues |
Country Status (22)
Country | Link |
---|---|
US (2) | US9403894B2 (xx) |
EP (1) | EP2585481B1 (xx) |
JP (1) | JP5937582B2 (xx) |
KR (1) | KR20130086339A (xx) |
CN (1) | CN103038250A (xx) |
AP (1) | AP3286A (xx) |
AR (1) | AR081975A1 (xx) |
AU (1) | AU2011269427A1 (xx) |
BR (1) | BR112012033227A2 (xx) |
CA (1) | CA2802889A1 (xx) |
CL (1) | CL2012003643A1 (xx) |
CO (1) | CO6660484A2 (xx) |
EA (1) | EA201291233A1 (xx) |
EC (1) | ECSP12012351A (xx) |
MX (1) | MX2012014774A (xx) |
NZ (1) | NZ604033A (xx) |
PE (1) | PE20130326A1 (xx) |
SG (1) | SG186276A1 (xx) |
TN (1) | TN2012000567A1 (xx) |
TW (1) | TW201202265A (xx) |
UY (1) | UY33462A (xx) |
WO (1) | WO2011160630A2 (xx) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA014184B1 (ru) | 2005-05-04 | 2010-10-29 | Зеаланд Фарма А/С | Аналоги глюкагонподобного пептида-2 (glp-2) |
JP5819586B2 (ja) | 2006-11-08 | 2015-11-24 | ジーランド ファーマ アクティーゼルスカブ | 選択的グルカゴン様ペプチド−2(glp−2)類似体 |
EA020520B1 (ru) | 2008-12-15 | 2014-11-28 | Зилэнд Фарма А/С | Аналоги глюкагона |
PL2370462T3 (pl) | 2008-12-15 | 2015-01-30 | Zealand Pharma As | Analogi glukagonu |
DK2370461T3 (da) | 2008-12-15 | 2013-12-16 | Zealand Pharma As | Glucagonanaloger |
EP2799447B1 (en) | 2008-12-15 | 2016-11-23 | Zealand Pharma A/S | Glucagon analogues |
WO2011006497A1 (en) | 2009-07-13 | 2011-01-20 | Zealand Pharma A/S | Acylated glucagon analogues |
AR081975A1 (es) | 2010-06-23 | 2012-10-31 | Zealand Pharma As | Analogos de glucagon |
CA2802897A1 (en) | 2010-06-24 | 2011-12-29 | Zealand Pharma A/S | Glucagon analogues |
JP2014504597A (ja) * | 2011-01-20 | 2014-02-24 | ジーランド ファーマ アクティーゼルスカブ | アシル化グルカゴン類似体とインスリン類似体の組合せ物 |
RU2610175C2 (ru) | 2011-09-23 | 2017-02-08 | Ново Нордиск А/С | Новые аналоги глюкагона |
AU2012357739A1 (en) * | 2011-12-23 | 2014-07-03 | Boehringer Ingelheim International Gmbh | Glucagon analogues |
SG11201407137PA (en) | 2012-05-03 | 2014-11-27 | Zealand Pharma As | Gip-glp-1 dual agonist compounds and methods |
KR20150006052A (ko) * | 2012-05-03 | 2015-01-15 | 질랜드 파마 에이/에스 | 글루카곤-유사 펩타이드-2 (glp-2) 유사체 |
SG11201407860PA (en) | 2012-06-14 | 2014-12-30 | Sanofi Sa | Exendin-4 peptide analogues |
SG11201500375PA (en) | 2012-07-23 | 2015-02-27 | Zealand Pharma As | Glucagon analogues |
EP2895506A1 (en) | 2012-09-17 | 2015-07-22 | Imperial Innovations Limited | Peptide analogues of glucagon and glp1 |
TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
GB2505941A (en) * | 2012-09-17 | 2014-03-19 | Imp Innovations Ltd | Peptide analogues of glucagon for the treatment of obesity and diabetes |
UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
SG11201503576XA (en) | 2012-12-21 | 2015-06-29 | Sanofi Sa | Exendin-4 Derivatives |
EP2976325B1 (en) | 2013-03-21 | 2017-03-01 | Sanofi-Aventis Deutschland GmbH | Synthesis of cyclic imide containing peptide products |
HUE034308T2 (en) | 2013-03-21 | 2018-02-28 | Sanofi Aventis Deutschland | Preparation of hydantoin-containing peptide products |
AR095986A1 (es) | 2013-04-03 | 2015-11-25 | Sanofi Sa | Proteínas modificadas que regulan glucosa en sangre con perfil alterado de actividad farmacológica y preparación de las mismas |
WO2014170496A1 (en) | 2013-04-18 | 2014-10-23 | Novo Nordisk A/S | Stable, protracted glp-1/glucagon receptor co-agonists for medical use |
KR102569036B1 (ko) | 2013-10-17 | 2023-08-23 | 질랜드 파마 에이/에스 | 아실화된 글루카곤 유사체 |
US9988429B2 (en) | 2013-10-17 | 2018-06-05 | Zealand Pharma A/S | Glucagon analogues |
CA2929459C (en) | 2013-11-06 | 2022-05-03 | Zealand Pharma A/S | Gip-glp-1 dual agonist compounds and methods |
AU2014345570B2 (en) | 2013-11-06 | 2019-01-24 | Zealand Pharma A/S | Glucagon-GLP-1-GIP triple agonist compounds |
EP3080149A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Dual glp-1/glucagon receptor agonists |
WO2015086731A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/glucagon receptor agonists |
TW201609796A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 非醯化之艾塞那肽-4(exendin-4)胜肽類似物 |
TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/gip受體促效劑 |
WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
CN106536547A (zh) | 2014-06-04 | 2017-03-22 | 诺和诺德股份有限公司 | 用于医疗用途的glp‑1/胰高血糖素受体共激动剂 |
US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
EP3985016A1 (en) | 2014-10-29 | 2022-04-20 | Zealand Pharma A/S | Gip agonist compounds and methods |
KR102121443B1 (ko) | 2015-02-17 | 2020-06-10 | 일라이 릴리 앤드 캄파니 | 저혈당증의 치료를 위한 비강 분말 제제 |
EA035791B1 (ru) | 2015-03-18 | 2020-08-11 | Зилэнд Фарма А/С | Аналоги амилина |
WO2016168388A2 (en) | 2015-04-14 | 2016-10-20 | Palatin Technologies, Inc. | Therapies for obesity, diabetes and related indications |
EP3283507B8 (en) | 2015-04-16 | 2019-11-13 | Zealand Pharma A/S | Acylated glucagon analogue |
AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
WO2016198624A1 (en) | 2015-06-12 | 2016-12-15 | Sanofi | Exendin-4 derivatives as trigonal glp-1/glucagon/gip receptor agonists |
WO2016198628A1 (en) | 2015-06-12 | 2016-12-15 | Sanofi | Non-acylated exendin-4 derivatives as dual glp-1/glucagon receptor agonists |
AR105284A1 (es) | 2015-07-10 | 2017-09-20 | Sanofi Sa | Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón |
CN109562144A (zh) | 2016-06-09 | 2019-04-02 | 阿米德生物有限责任公司 | 胰高血糖素类似物及其使用方法 |
HUE054928T2 (hu) | 2016-08-05 | 2021-10-28 | Boehringer Ingelheim Int | Oxadiazolopiridin-származékok ghrelin O-aciltranszferáz (GOAT)-inhibitorokként törtenõ alkalmazásra |
AR109514A1 (es) | 2016-09-09 | 2018-12-19 | Zealand Pharma As | Análogos de amilina |
KR101887577B1 (ko) | 2016-10-19 | 2018-09-10 | (주)케어젠 | 항비만 및 항당뇨 효능을 갖는 펩타이드 및 이의 용도 |
TW201832783A (zh) | 2016-12-02 | 2018-09-16 | 法商賽諾菲公司 | 包含glp-1/胰高血糖素雙重激動劑、連接子和透明質酸的接合物 |
JP6563614B1 (ja) | 2016-12-09 | 2019-08-21 | ジーランド・ファーマ・ア/エス | アシル化glp−1/glp−2二重アゴニスト |
CN117603337A (zh) * | 2017-08-16 | 2024-02-27 | 东亚St株式会社 | 酰化胃泌酸调节素肽类似物 |
JP7225253B2 (ja) | 2018-02-02 | 2023-02-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グレリンo-アシルトランスフェラーゼ(goat)阻害剤として使用するためのピラゾール置換及びインダゾール置換オキサジアゾロピリジン誘導体 |
CR20200329A (es) | 2018-02-02 | 2020-09-04 | Boehringer Ingelheim Int | Derivados de triazolopirimidina para usar como inhibidores de ghrelin o-acil transferasa (goat) |
JP7150032B2 (ja) | 2018-02-02 | 2022-10-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | グレリンo-アシルトランスフェラーゼ(goat)阻害薬として使用するためのヘテロシクリル置換オキサジアゾロピリジン誘導体 |
EP3746451B1 (en) | 2018-02-02 | 2023-07-12 | Boehringer Ingelheim International GmbH | Benzyl-, (pyridin-3-yl)methyl- or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin o-acyl transferase (goat) inhibitors |
WO2019197469A1 (en) | 2018-04-10 | 2019-10-17 | Sanofi-Aventis Deutschland Gmbh | Lixisenatide synthesis with capping |
US11560402B2 (en) * | 2018-04-10 | 2023-01-24 | Sanofi-Aventis Deutschland Gmbh | Method for cleavage of solid phase-bound peptides from the solid phase |
TW202024134A (zh) | 2018-12-21 | 2020-07-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 雙特異性蛋白 |
TWI771669B (zh) | 2019-04-26 | 2022-07-21 | 美商美國禮來大藥廠 | 製備穩定胜肽調配物之方法 |
MX2022005661A (es) | 2019-11-11 | 2022-09-07 | Boehringer Ingelheim Int | Agonistas del receptor npy2. |
ES2984466T3 (es) | 2020-05-22 | 2024-10-29 | Boehringer Ingelheim Int | Procedimiento de fabricación de 7-amino-5-metil-[1,2,5]oxadiazolo[3,4-b]piridín-carboxilato de alquilo |
WO2021233884A1 (en) | 2020-05-22 | 2021-11-25 | Boehringer Ingelheim International Gmbh | Continuous process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate |
CN113292646B (zh) * | 2020-05-29 | 2022-05-13 | 东莞云璟生物技术有限公司 | Glp-1/胰高血糖素双重激动剂融合蛋白 |
CA3185637A1 (en) | 2020-08-07 | 2022-02-10 | Boehringer Ingelheim International Gmbh | Soluble npy2 receptor agonists |
WO2024165571A2 (en) | 2023-02-06 | 2024-08-15 | E-Therapeutics Plc | Inhibitors of expression and/or function |
Citations (3)
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WO2008152403A1 (en) * | 2007-06-15 | 2008-12-18 | Zealand Pharma A/S | Glucagon analogues |
WO2010070255A1 (en) * | 2008-12-15 | 2010-06-24 | Zealand Pharma A/S | Glucagon analogues |
WO2011088837A1 (en) * | 2010-01-20 | 2011-07-28 | Zealand Pharma A/S | Treatment of cardiac conditions |
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- 2011-06-22 UY UY0001033462A patent/UY33462A/es not_active Application Discontinuation
- 2011-06-23 NZ NZ604033A patent/NZ604033A/en not_active IP Right Cessation
- 2011-06-23 EP EP11741513.3A patent/EP2585481B1/en active Active
- 2011-06-23 CA CA2802889A patent/CA2802889A1/en not_active Abandoned
- 2011-06-23 US US13/702,841 patent/US9403894B2/en not_active Expired - Fee Related
- 2011-06-23 EA EA201291233A patent/EA201291233A1/ru unknown
- 2011-06-23 PE PE2012002434A patent/PE20130326A1/es not_active Application Discontinuation
- 2011-06-23 MX MX2012014774A patent/MX2012014774A/es not_active Application Discontinuation
- 2011-06-23 TW TW100122081A patent/TW201202265A/zh unknown
- 2011-06-23 KR KR1020137000529A patent/KR20130086339A/ko not_active Application Discontinuation
- 2011-06-23 AP AP2013006669A patent/AP3286A/xx active
- 2011-06-23 BR BR112012033227A patent/BR112012033227A2/pt not_active IP Right Cessation
- 2011-06-23 SG SG2012090890A patent/SG186276A1/en unknown
- 2011-06-23 WO PCT/DK2011/000067 patent/WO2011160630A2/en active Application Filing
- 2011-06-23 JP JP2013515697A patent/JP5937582B2/ja not_active Expired - Fee Related
- 2011-06-23 CN CN2011800305150A patent/CN103038250A/zh active Pending
- 2011-06-23 AU AU2011269427A patent/AU2011269427A1/en not_active Abandoned
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2012
- 2012-11-30 TN TNP2012000567A patent/TN2012000567A1/en unknown
- 2012-12-20 EC ECSP12012351 patent/ECSP12012351A/es unknown
- 2012-12-21 CL CL2012003643A patent/CL2012003643A1/es unknown
- 2012-12-21 CO CO12232550A patent/CO6660484A2/es unknown
-
2016
- 2016-06-27 US US15/194,025 patent/US20160304576A1/en not_active Abandoned
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WO2008152403A1 (en) * | 2007-06-15 | 2008-12-18 | Zealand Pharma A/S | Glucagon analogues |
WO2010070255A1 (en) * | 2008-12-15 | 2010-06-24 | Zealand Pharma A/S | Glucagon analogues |
WO2011088837A1 (en) * | 2010-01-20 | 2011-07-28 | Zealand Pharma A/S | Treatment of cardiac conditions |
Also Published As
Publication number | Publication date |
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US9403894B2 (en) | 2016-08-02 |
AU2011269427A1 (en) | 2012-12-20 |
CA2802889A1 (en) | 2011-12-29 |
UY33462A (es) | 2012-01-31 |
TW201202265A (en) | 2012-01-16 |
MX2012014774A (es) | 2013-01-29 |
AR081975A1 (es) | 2012-10-31 |
ECSP12012351A (es) | 2013-01-31 |
KR20130086339A (ko) | 2013-08-01 |
NZ604033A (en) | 2014-12-24 |
US20130157935A1 (en) | 2013-06-20 |
US20160304576A1 (en) | 2016-10-20 |
JP5937582B2 (ja) | 2016-06-22 |
JP2013534919A (ja) | 2013-09-09 |
SG186276A1 (en) | 2013-01-30 |
CO6660484A2 (es) | 2013-04-30 |
EA201291233A1 (ru) | 2013-07-30 |
WO2011160630A3 (en) | 2012-02-16 |
PE20130326A1 (es) | 2013-03-17 |
EP2585481B1 (en) | 2015-08-19 |
CN103038250A (zh) | 2013-04-10 |
BR112012033227A2 (pt) | 2017-06-20 |
CL2012003643A1 (es) | 2013-08-02 |
WO2011160630A2 (en) | 2011-12-29 |
AP2013006669A0 (en) | 2013-01-31 |
EP2585481A2 (en) | 2013-05-01 |
TN2012000567A1 (en) | 2014-04-01 |
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