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OA06310A - Nouveaux dérivés N-substitués de l'acide aziridinyl-2-carboxylique et leur procédé de préparation. - Google Patents

Nouveaux dérivés N-substitués de l'acide aziridinyl-2-carboxylique et leur procédé de préparation.

Info

Publication number
OA06310A
OA06310A OA56865A OA56865A OA06310A OA 06310 A OA06310 A OA 06310A OA 56865 A OA56865 A OA 56865A OA 56865 A OA56865 A OA 56865A OA 06310 A OA06310 A OA 06310A
Authority
OA
OAPI
Prior art keywords
aziridinyl
new
carboxylic acid
preparation process
substituted derivatives
Prior art date
Application number
OA56865A
Other languages
English (en)
French (fr)
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of OA06310A publication Critical patent/OA06310A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
OA56865A 1978-08-03 1979-08-03 Nouveaux dérivés N-substitués de l'acide aziridinyl-2-carboxylique et leur procédé de préparation. OA06310A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782833986 DE2833986A1 (de) 1978-08-03 1978-08-03 Immunstimulierende n-substituierte aziridin-2-carbonsaeurederivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese substanzen enthalten

Publications (1)

Publication Number Publication Date
OA06310A true OA06310A (fr) 1981-06-30

Family

ID=6046078

Family Applications (1)

Application Number Title Priority Date Filing Date
OA56865A OA06310A (fr) 1978-08-03 1979-08-03 Nouveaux dérivés N-substitués de l'acide aziridinyl-2-carboxylique et leur procédé de préparation.

Country Status (39)

Country Link
US (3) US4321194A (es)
JP (2) JPS5522694A (es)
KR (1) KR860000320B1 (es)
AR (1) AR228945A1 (es)
AT (1) AT379382B (es)
AU (1) AU524572B2 (es)
BE (1) BE878020A (es)
CA (1) CA1142530A (es)
CH (1) CH645540A5 (es)
CS (1) CS227301B2 (es)
DD (1) DD145267A5 (es)
DE (1) DE2833986A1 (es)
DK (1) DK156431C (es)
EG (1) EG14369A (es)
ES (1) ES483116A1 (es)
FI (1) FI70570C (es)
FR (2) FR2432317A1 (es)
GB (2) GB2026863B (es)
GR (1) GR74424B (es)
HK (1) HK13285A (es)
HU (1) HU184610B (es)
IE (1) IE48462B1 (es)
IL (1) IL57939A (es)
IT (1) IT1123503B (es)
KE (1) KE3493A (es)
LU (1) LU81563A1 (es)
MY (1) MY8600045A (es)
NL (1) NL187239C (es)
NO (1) NO152413C (es)
NZ (1) NZ191169A (es)
OA (1) OA06310A (es)
PH (1) PH19007A (es)
PL (1) PL126531B1 (es)
PT (1) PT70009A (es)
SE (1) SE445552B (es)
SG (1) SG85784G (es)
SU (1) SU1145927A3 (es)
YU (1) YU41169B (es)
ZA (1) ZA793966B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3446713A1 (de) * 1984-12-21 1986-06-26 Boehringer Mannheim Gmbh, 6800 Mannheim N-substituierte aziridin-2-carbonsaeurederivate, verfahren zu deren herstellung sowie diese substanzen enthaltende arzneimittel
JPS6287512A (ja) * 1985-10-11 1987-04-22 ベ−リンガ−・マンハイム・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 選択的免疫抑制剤
US4925835A (en) * 1986-05-01 1990-05-15 Sloan-Kettering Institute For Cancer Research Aziridinyl putrescine containing compositions and their uses in treating prostate cancer
KR19980083844A (ko) * 1997-05-19 1998-12-05 이웅열 새로운 아지리딘 유도체 및 그 제조방법
FR2776292B1 (fr) * 1998-03-20 2004-09-10 Oncopharm Cephalotaxanes porteurs de chaine laterale et leur procede de synthese
KR20010000195A (ko) * 2000-08-10 2001-01-05 하현준 (2r)- 및 (2s)-아지리딘-2-카르복실산 에스테르 및(2r)- 및 (2s)-2-히드록시메틸 아지리딘 제조 방법
CA2431947A1 (en) * 2000-11-21 2002-05-30 Gabriel Lopez-Berestein Composition comprising an imexon or derivatives thereof and lipids
US20030129222A1 (en) * 2000-11-21 2003-07-10 Gabriel Lopez-Berestein Liposomal imexon
US6982263B2 (en) * 2001-06-08 2006-01-03 Boehringer Ingelheim Pharmaceuticals, Inc. Nitriles useful as reversible inhibitors of cysteine proteases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470223A1 (de) * 1962-09-05 1969-12-04 Siegfried Ag Verfahren zur Herstellung neuer stickstoffhaltiger Heterocyclen
DE2528460A1 (de) * 1975-06-26 1977-01-13 Boehringer Mannheim Gmbh Verwendung von l-carboxamido-2- cyan-aziridin als immunstimulans
DE2530960A1 (de) 1975-07-11 1977-01-27 Huels Chemische Werke Ag 2-(n-substituierte)-aziridinyl-delta hoch 2 -oxazoline und verfahren zu ihrer herstellung
DE2538672A1 (de) * 1975-08-30 1977-03-10 Boehringer Mannheim Gmbh Verwendung von derivaten der propionsaeure
DE2656240C2 (de) * 1976-12-11 1983-11-03 Boehringer Mannheim Gmbh, 6800 Mannheim Neue Aziridin-Derivate, Verfahren zu deren Herstellung und pharmazeutische Mittel
CA1092606A (en) * 1976-10-05 1980-12-30 Herbert Berger 1-(n-acylcarbamoyl)-2-cyano-aziridines and the preparation thereof
GB1550065A (en) * 1976-10-29 1979-08-08 Inst Organicheskogo Sinteza Ak Pharmaceutical composition processing antitumour activity
AR218645A1 (es) * 1976-12-11 1980-06-30 Boehringer Mannheim Gmbh Procedimiento para preparar derivados de esteres del acido 1-aziridina-carboxilico

Also Published As

Publication number Publication date
PT70009A (de) 1979-08-01
FI70570C (fi) 1986-09-24
FR2432317A1 (fr) 1980-02-29
IT7924769A0 (it) 1979-07-30
DK156431B (da) 1989-08-21
MY8600045A (en) 1986-12-31
IE48462B1 (en) 1985-01-23
YU41169B (en) 1986-12-31
JPH0257523B2 (es) 1990-12-05
LU81563A1 (de) 1980-08-08
NO152413C (no) 1985-09-25
JPS63258415A (ja) 1988-10-25
IE791478L (en) 1980-02-03
GB2026863A (en) 1980-02-13
NO152413B (no) 1985-06-17
HU184610B (en) 1984-09-28
ES483116A1 (es) 1980-04-16
KE3493A (en) 1985-02-01
IL57939A0 (en) 1979-11-30
IL57939A (en) 1985-02-28
PL126531B1 (en) 1983-08-31
CA1142530A (en) 1983-03-08
DK156431C (da) 1990-01-22
FI792393A (fi) 1980-02-04
SG85784G (en) 1985-06-07
IT1123503B (it) 1986-04-30
US4409236A (en) 1983-10-11
EG14369A (en) 1983-12-31
ATA531479A (de) 1985-05-15
DE2833986A1 (de) 1980-02-21
SU1145927A3 (ru) 1985-03-15
NO792545L (no) 1980-02-05
YU188179A (en) 1983-06-30
FR2445316B1 (es) 1983-07-29
GR74424B (es) 1984-06-28
KR830000902A (ko) 1983-04-28
NL187239C (nl) 1991-07-16
DK320379A (da) 1980-02-04
JPS5522694A (en) 1980-02-18
GB2106896B (en) 1983-08-17
GB2026863B (en) 1983-03-30
FR2445316A1 (fr) 1980-07-25
AR228945A1 (es) 1983-05-13
US4321194A (en) 1982-03-23
JPS6243991B2 (es) 1987-09-17
FR2432317B1 (es) 1983-03-18
DE2833986C2 (es) 1988-04-07
KR860000320B1 (ko) 1986-04-09
GB2106896A (en) 1983-04-20
DD145267A5 (de) 1980-12-03
FI70570B (fi) 1986-06-06
PH19007A (en) 1985-12-03
CH645540A5 (de) 1984-10-15
HK13285A (en) 1985-03-01
ZA793966B (en) 1980-08-27
US4410532A (en) 1983-10-18
SE7906461L (sv) 1980-02-04
SE445552B (sv) 1986-06-30
PL217527A1 (es) 1980-07-01
NL7905855A (nl) 1980-02-05
AU524572B2 (en) 1982-09-23
AU4930879A (en) 1980-02-07
BE878020A (fr) 1980-02-01
AT379382B (de) 1985-12-27
CS227301B2 (en) 1984-04-16
NZ191169A (en) 1981-01-23

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