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NO864674D0 - Fremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser. - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser.

Info

Publication number
NO864674D0
NO864674D0 NO864674A NO864674A NO864674D0 NO 864674 D0 NO864674 D0 NO 864674D0 NO 864674 A NO864674 A NO 864674A NO 864674 A NO864674 A NO 864674A NO 864674 D0 NO864674 D0 NO 864674D0
Authority
NO
Norway
Prior art keywords
cefem
relations
procedure
preparation
therapeutic active
Prior art date
Application number
NO864674A
Other languages
English (en)
Other versions
NO864674L (no
Inventor
Takao Takaya
Kazuo Sakane
Kenzi Miyai
Kohji Kawabata
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858528803A external-priority patent/GB8528803D0/en
Priority claimed from GB868610720A external-priority patent/GB8610720D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of NO864674D0 publication Critical patent/NO864674D0/no
Publication of NO864674L publication Critical patent/NO864674L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO864674A 1985-11-22 1986-11-21 Fremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser. NO864674L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858528803A GB8528803D0 (en) 1985-11-22 1985-11-22 Cephem compounds
GB868610720A GB8610720D0 (en) 1986-05-01 1986-05-01 Cephem compounds

Publications (2)

Publication Number Publication Date
NO864674D0 true NO864674D0 (no) 1986-11-21
NO864674L NO864674L (no) 1987-05-25

Family

ID=26290033

Family Applications (1)

Application Number Title Priority Date Filing Date
NO864674A NO864674L (no) 1985-11-22 1986-11-21 Fremgangsmaate for fremstilling av terapeutisk aktive cefemforbindelser.

Country Status (14)

Country Link
US (1) US4960766A (no)
EP (1) EP0223246B1 (no)
JP (1) JPH07116201B2 (no)
KR (1) KR940000111B1 (no)
CN (1) CN86107947A (no)
AU (1) AU6556186A (no)
DE (1) DE3689684T2 (no)
DK (1) DK560486A (no)
FI (1) FI864658A (no)
HU (1) HUT43079A (no)
IL (1) IL80669A0 (no)
NO (1) NO864674L (no)
OA (1) OA08444A (no)
PT (1) PT83794B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194432A (en) * 1985-11-22 1993-03-16 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
CA1293719C (en) * 1986-09-22 1991-12-31 Takao Takaya Cephem compounds and processes for preparation thereof
IL86941A (en) * 1987-07-10 1993-07-08 Gist Brocades Nv Process for the preparation of cephem compounds and some new cephalosporin derivatives prepared by this process
US5210080A (en) * 1987-09-07 1993-05-11 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US5663163A (en) * 1987-09-07 1997-09-02 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
IE63094B1 (en) * 1987-09-14 1995-03-22 Fujisawa Pharmaceutical Co Cephem compound and a process for preparation thereof
GB8905301D0 (en) * 1989-03-08 1989-04-19 Fujisawa Pharmaceutical Co New cephem compound and a process for preparation thereof
EP0517041A1 (en) * 1991-06-07 1992-12-09 Fujisawa Pharmaceutical Co., Ltd. New Cephem Compounds
AUPN955596A0 (en) * 1996-04-30 1996-05-23 Fujisawa Pharmaceutical Co., Ltd. New compound
ATE473986T1 (de) 2003-04-16 2010-07-15 Sandoz Ag Verfahren zur herstellung von cefepim
US7847093B2 (en) * 2003-04-16 2010-12-07 Sandoz Ag Processes for the preparations of cefepime
WO2005019227A1 (en) * 2003-08-22 2005-03-03 Orchid Chemicals & Pharmaceuticals Ltd Process for the preparation of cephalosporin antibiotic
CN102336771A (zh) * 2011-07-11 2012-02-01 珠海联邦制药股份有限公司 一种硫酸头孢噻利中间体的制备方法
JP6151257B2 (ja) 2011-09-09 2017-06-21 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 肺内感染症の治療方法
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
BR112015023523B8 (pt) 2013-03-15 2023-03-07 Merck Sharp & Dohme Composições farmacêuticas e recipiente de forma de dosagem única
ES2800603T3 (es) 2013-09-09 2021-01-04 Merck Sharp & Dohme Tratamiento de infecciones con ceftolozano/tazobactam en sujetos con insuficiencia renal
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
ES485441A1 (es) * 1978-10-27 1980-07-01 Glaxo Group Ltd Un procedimiento para la preparacion de antibioticos de ce- falosporina
ES485937A1 (es) * 1978-11-15 1980-07-01 Glaxo Group Ltd Un procedimiento para la preparacion de antibioticos de ce- falosporina
BE880037A (fr) * 1978-11-15 1980-05-14 Glaxo Group Ltd Cephalosporines a activite antibiotique et procede de preparation
NZ192943A (en) * 1979-02-23 1982-12-21 Glaxo Group Ltd Cephalosporin antibiotics
GR78245B (no) * 1980-09-12 1984-09-26 Ciba Geigy Ag
JPS584789A (ja) * 1981-04-03 1983-01-11 Fujisawa Pharmaceut Co Ltd 新規セフエム化合物およびその製造法
DE3279470D1 (en) 1981-04-03 1989-04-06 Fujisawa Pharmaceutical Co New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
US4401668A (en) * 1981-10-02 1983-08-30 Eli Lilly And Company Pyrazinium substituted cephalosporins
US4616081A (en) * 1982-07-07 1986-10-07 Asahi Kasei Kogyo Kabushiki Kaisha Cephalosporin compounds
GB2125033B (en) * 1982-07-23 1985-08-29 Servipharm Ltd Cephalosporins
DE3330605A1 (de) * 1983-08-25 1985-03-14 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
JPS6067483A (ja) * 1983-09-24 1985-04-17 Sankyo Co Ltd チアゾリオメチル置換基を有するセフアロスポリン誘導体
JPS6067484A (ja) * 1983-09-26 1985-04-17 Sankyo Co Ltd ピリダジニウムメチル置換基を有するセフアロスポリン誘導体
DE3336755A1 (de) * 1983-10-08 1985-04-25 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3336757A1 (de) * 1983-10-08 1985-04-25 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
NO864674L (no) 1987-05-25
EP0223246B1 (en) 1994-03-02
PT83794B (en) 1988-10-19
KR940000111B1 (ko) 1994-01-05
KR870004995A (ko) 1987-06-04
DE3689684D1 (de) 1994-04-07
JPS62174085A (ja) 1987-07-30
HUT43079A (en) 1987-09-28
FI864658A (fi) 1987-05-23
DK560486D0 (da) 1986-11-21
OA08444A (fr) 1988-06-30
DK560486A (da) 1987-05-23
FI864658A0 (fi) 1986-11-17
US4960766A (en) 1990-10-02
PT83794A (en) 1986-12-01
DE3689684T2 (de) 1994-06-23
EP0223246A3 (en) 1988-11-23
EP0223246A2 (en) 1987-05-27
JPH07116201B2 (ja) 1995-12-13
CN86107947A (zh) 1987-05-27
AU6556186A (en) 1987-05-28
IL80669A0 (en) 1987-02-27

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