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NO20061441L - Nye tiotropiumsalter, metoder for deres fremstilling, og farmasoytiske formuleringer inneholdende disse - Google Patents

Nye tiotropiumsalter, metoder for deres fremstilling, og farmasoytiske formuleringer inneholdende disse

Info

Publication number
NO20061441L
NO20061441L NO20061441A NO20061441A NO20061441L NO 20061441 L NO20061441 L NO 20061441L NO 20061441 A NO20061441 A NO 20061441A NO 20061441 A NO20061441 A NO 20061441A NO 20061441 L NO20061441 L NO 20061441L
Authority
NO
Norway
Prior art keywords
preparation
methods
formulations containing
pharmaceutical formulations
tiotropium salts
Prior art date
Application number
NO20061441A
Other languages
English (en)
Inventor
Rolf Banholzer
Waldemar Pfrengle
Peter Sieger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34530661&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20061441(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NO20061441L publication Critical patent/NO20061441L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Oppfinnelsen angår nye tiotropiumsalter, metoder for fremstilling av disse, legemiddelformuleringer som inneholder disse, og anvendelsen derav for fremstilling av et legemiddel som blir anvendt for behandling av luftveislidelser, spesielt KOLS (kronisk obstmktiv lungesykdom) og astma.
NO20061441A 2003-11-03 2006-03-30 Nye tiotropiumsalter, metoder for deres fremstilling, og farmasoytiske formuleringer inneholdende disse NO20061441L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03025076 2003-11-03
PCT/EP2004/012270 WO2005042528A1 (de) 2003-11-03 2004-10-29 Neue tiotropiumsalze, verfahren zu deren herstellung sowie diese enthaltende arzneimittelformulierungen

Publications (1)

Publication Number Publication Date
NO20061441L true NO20061441L (no) 2006-07-12

Family

ID=34530661

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061441A NO20061441L (no) 2003-11-03 2006-03-30 Nye tiotropiumsalter, metoder for deres fremstilling, og farmasoytiske formuleringer inneholdende disse

Country Status (29)

Country Link
US (1) US20050096341A1 (no)
EP (5) EP2336127A1 (no)
JP (1) JP5165245B2 (no)
KR (1) KR20060102561A (no)
CN (3) CN102964344B (no)
AR (1) AR046318A1 (no)
AT (1) ATE478071T1 (no)
AU (1) AU2004285685B2 (no)
CA (1) CA2544357A1 (no)
CO (1) CO5690554A2 (no)
DE (1) DE502004011562D1 (no)
DK (2) DK1682543T3 (no)
EA (1) EA012369B1 (no)
EC (2) ECSP066545A (no)
ES (2) ES2422730T3 (no)
HK (1) HK1099753A1 (no)
IL (1) IL175127A (no)
MY (1) MY145166A (no)
NO (1) NO20061441L (no)
NZ (1) NZ547523A (no)
PE (1) PE20050485A1 (no)
PL (1) PL2083007T3 (no)
RS (1) RS20060293A (no)
SG (1) SG149876A1 (no)
TW (1) TW200523263A (no)
UA (1) UA82414C2 (no)
UY (1) UY28589A1 (no)
WO (1) WO2005042528A1 (no)
ZA (1) ZA200602343B (no)

Families Citing this family (16)

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Publication number Priority date Publication date Assignee Title
DE502004010885D1 (de) 2003-11-03 2010-04-22 Boehringer Ingelheim Pharma Verfahren zur herstellung von tiotropiumsalzen
RU2418796C2 (ru) * 2005-06-15 2011-05-20 Берингер Ингельхайм Интернациональ Гмбх Способ получения новых солей тиотропия
JP2008543806A (ja) * 2005-06-17 2008-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療のためのｍｒｐｉｖインヒビター
DE102005035112A1 (de) * 2005-07-27 2007-02-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Verfahren zur Herstellung von Tiotropiumsalzen unter Anwendung von in organischen Lösungsmitteln löslichen N-Methylscopiniumsalzen
WO2007075858A2 (en) * 2005-12-19 2007-07-05 Sicor Inc. Novel forms of tiotropium bromide and processes for preparation thereof
KR20080079586A (ko) * 2005-12-19 2008-09-01 시코르, 인크. 순수하고 안정한 티오트로퓸 브로마이드
US20070167480A1 (en) * 2005-12-19 2007-07-19 Sicor Inc. Pure and stable tiotropium bromide
US9108962B2 (en) 2005-12-19 2015-08-18 Sicor, Inc. Forms of tiotropium bromide and processes for preparation thereof
US20080051582A1 (en) * 2006-07-10 2008-02-28 Sicor Inc. Process for the preparation of tiotropium bromide
EP1925295A1 (de) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
WO2008089852A1 (de) * 2007-01-26 2008-07-31 Boehringer Ingelheim Pharma Gmbh & Co.Kg Neues verfahren zur herstellung von tiotropiumsalzen
EP1953156A1 (de) * 2007-01-29 2008-08-06 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung von Scopiniumsalzen
EP2411008B1 (en) * 2009-03-27 2017-03-22 Mahmut Bilgic Complexes of tiotropium with improved properties of solubility and stability
PL388070A1 (pl) * 2009-05-19 2010-11-22 Adamed Spółka Z Ograniczoną Odpowiedzialnością Nowe sole tiotropium
CZ201241A3 (cs) * 2012-01-20 2013-07-31 Zentiva, K.S. Nové polymorfní formy tiotropium jodidu a zpusob jejich prípravy
JP6335798B2 (ja) * 2012-02-28 2018-05-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規噴射剤含有チオトロピウム製剤

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US2597329A (en) * 1947-08-06 1952-05-20 Merck & Co Inc Process for anion exchange of thiamin salts
US3551492A (en) * 1967-10-31 1970-12-29 Ciba Geigy Corp N,n'-diaminoalkoxy-benzyl-diamino-alkanes and the salts thereof
US4570630A (en) 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
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US5610163A (en) * 1989-09-16 1997-03-11 Boehringer Ingelheim Gmbh Esters of thienyl carboxylic acids and amino alcohols and their quaternization products
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DE4318455A1 (de) 1993-06-03 1994-12-08 Boehringer Ingelheim Kg Kapselhalterung
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
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US6908928B2 (en) * 2000-10-12 2005-06-21 Bi Pharma Kg. Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions
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DE10056104A1 (de) * 2000-11-13 2002-05-23 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Tiotropiumsalzen und Salzen des Salmeterols
DE10061877A1 (de) * 2000-12-12 2002-06-13 Basf Ag Verfahren zur Herstellung wässriger Copolymerisatdispersionen von Copolymerisaten aus Kohlenmonoxid und wenigstens einer olefinisch ungesättigten Verbindung
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US20020193394A1 (en) * 2001-03-13 2002-12-19 Bernd Disse Compounds for treating inflammatory diseases
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SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
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RU2418796C2 (ru) * 2005-06-15 2011-05-20 Берингер Ингельхайм Интернациональ Гмбх Способ получения новых солей тиотропия

Also Published As

Publication number Publication date
UA82414C2 (uk) 2008-04-10
EP2322522A1 (de) 2011-05-18
EP2083007B1 (de) 2013-04-24
IL175127A (en) 2011-10-31
MY145166A (en) 2011-12-30
CN1875020A (zh) 2006-12-06
AU2004285685B2 (en) 2011-03-24
CN102964344A (zh) 2013-03-13
CN101648950A (zh) 2010-02-17
CN101648950B (zh) 2014-05-07
AU2004285685A1 (en) 2005-05-12
CN1875020B (zh) 2010-04-28
EP2336127A1 (de) 2011-06-22
NZ547523A (en) 2009-07-31
KR20060102561A (ko) 2006-09-27
JP5165245B2 (ja) 2013-03-21
ECSP066544A (es) 2006-10-17
ZA200602343B (en) 2007-12-27
HK1099753A1 (en) 2007-08-24
UY28589A1 (es) 2005-06-30
DK1682543T3 (da) 2010-12-13
EP1682543A1 (de) 2006-07-26
EP1682543B1 (de) 2010-08-18
ES2422730T3 (es) 2013-09-13
RS20060293A (en) 2008-08-07
CN102964344B (zh) 2014-12-31
EP2083007A1 (de) 2009-07-29
EA012369B1 (ru) 2009-10-30
SG149876A1 (en) 2009-02-27
TW200523263A (en) 2005-07-16
EA200600854A1 (ru) 2006-10-27
ES2350981T3 (es) 2011-01-28
DE502004011562D1 (de) 2010-09-30
IL175127A0 (en) 2006-09-05
PL2083007T3 (pl) 2013-09-30
PE20050485A1 (es) 2005-10-05
CA2544357A1 (en) 2005-05-12
EP2319844A1 (de) 2011-05-11
AR046318A1 (es) 2005-11-30
CO5690554A2 (es) 2006-10-31
DK2083007T3 (da) 2013-07-29
JP2007509895A (ja) 2007-04-19
ATE478071T1 (de) 2010-09-15
WO2005042528A1 (de) 2005-05-12
US20050096341A1 (en) 2005-05-05
ECSP066545A (es) 2006-10-17

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