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NO20050801L - Prodrug av protonpumpe inhibitorer - Google Patents

Prodrug av protonpumpe inhibitorer

Info

Publication number
NO20050801L
NO20050801L NO20050801A NO20050801A NO20050801L NO 20050801 L NO20050801 L NO 20050801L NO 20050801 A NO20050801 A NO 20050801A NO 20050801 A NO20050801 A NO 20050801A NO 20050801 L NO20050801 L NO 20050801L
Authority
NO
Norway
Prior art keywords
proton pump
pump inhibitors
prodrug
prodrugs
bioavailability
Prior art date
Application number
NO20050801A
Other languages
English (en)
Norwegian (no)
Inventor
George Sachs
Jai Moo Shin
Michael E Garst
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of NO20050801L publication Critical patent/NO20050801L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
NO20050801A 2002-07-19 2005-02-15 Prodrug av protonpumpe inhibitorer NO20050801L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39745902P 2002-07-19 2002-07-19
PCT/US2003/022419 WO2004009583A2 (en) 2002-07-19 2003-07-15 Benzimidazole derivatives and their use as prodrugs of proton pump inhibitor

Publications (1)

Publication Number Publication Date
NO20050801L true NO20050801L (no) 2005-02-15

Family

ID=30771064

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050801A NO20050801L (no) 2002-07-19 2005-02-15 Prodrug av protonpumpe inhibitorer

Country Status (23)

Country Link
US (3) US6897227B2 (de)
EP (1) EP1556371B1 (de)
JP (1) JP4463103B2 (de)
KR (2) KR100788778B1 (de)
AT (1) ATE323695T1 (de)
AU (1) AU2003259154B2 (de)
BR (1) BR0312802A (de)
CA (1) CA2492718C (de)
CO (1) CO5690576A2 (de)
DE (1) DE60304726T2 (de)
DK (1) DK1556371T3 (de)
ES (1) ES2263028T3 (de)
HK (1) HK1079207A1 (de)
IL (1) IL166371A0 (de)
MX (1) MXPA05000657A (de)
NO (1) NO20050801L (de)
NZ (1) NZ538221A (de)
PL (1) PL375255A1 (de)
PT (1) PT1556371E (de)
RU (1) RU2292342C2 (de)
TW (1) TW200502231A (de)
WO (1) WO2004009583A2 (de)
ZA (1) ZA200501116B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
JP4634144B2 (ja) * 2002-08-01 2011-02-16 ニコックス エスエー ニトロソ化プロトンポンプ阻害剤、組成物および使用方法
JP2007521314A (ja) * 2003-07-15 2007-08-02 アラーガン、インコーポレイテッド プロトンポンプ阻害薬の異性体純粋なプロドラッグを製造するための方法
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
US20060241037A1 (en) * 2003-10-03 2006-10-26 Allergan Inc. Compositions comprising trefoil factor family peptides and/or mucoadhesives and proton pump ihhibitor prodrugs
EP1715854A2 (de) * 2004-02-18 2006-11-02 Allergan, Inc. Prodrugs für die intravenöse verabreichung von protonenpumpen-hemmern
CA2556756A1 (en) * 2004-02-18 2005-09-09 Allergan, Inc. Compositions comprising prodrugs of proton pump inhibitors
WO2005089758A1 (en) * 2004-03-11 2005-09-29 Allergan, Inc. Methods and compositions for the treatment of conditions related to gastric acid secretion
ATE437869T1 (de) 2004-04-28 2009-08-15 Hetero Drugs Ltd Verfahren zur herstellung von pyridinylmethyl-1h- benzimidazolverbindungen in enantiomerenangereicherter form oder als einzelne enantiomere
WO2007073301A1 (en) * 2005-12-23 2007-06-28 Astrazeneca Ab Benzoimidazole derivatives as prodrugs of proton pump inhibitors
US20070265311A1 (en) * 2006-01-10 2007-11-15 Rubino Mark P Therapeutic Salt Compositions and Methods
BRPI0711048A2 (pt) * 2006-05-09 2011-08-23 Astrazeneca Ab formulações parenteral esterilizada e sólida estáveis, solução para administração parenteral, processos para a preparação de uma formulação e para a fabricação de um produto, método para prevenir ou tratar doenças gastrintestinais, uso de uma formulação sólida estável
US20070293543A1 (en) * 2006-06-19 2007-12-20 Edward Lee THRESHOLD BLOOD OMEPRAZOLE CONCENTRATION IS 50 NG/ML FOR THE MAINTENANCE OF INTRAGASTRIC pH OF AT LEAST 4.0 AFTER ORAL DOSING WITH CMA-OMEPRAZOLE, AGN 201904-Z
WO2008036211A1 (en) * 2006-09-19 2008-03-27 Alevium Pharmaceuticals, Inc. Prodrugs of proton pump inhibitors including the (1h-pyrrol-1-yl)-1h-benzimidazole moiety
US20100317689A1 (en) * 2006-09-19 2010-12-16 Garst Michael E Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
WO2009044976A1 (en) * 2007-10-05 2009-04-09 Lg Electronics Inc. Plasma display device
KR20090035195A (ko) * 2007-10-05 2009-04-09 엘지전자 주식회사 플라즈마 디스플레이 장치
KR100895333B1 (ko) * 2007-11-01 2009-05-07 엘지전자 주식회사 플라즈마 디스플레이 패널의 구동 방법 및 그를 이용한플라즈마 디스플레이 장치
US8927559B2 (en) 2010-10-11 2015-01-06 Merck Sharp & Dohme Corp. Quinazolinone-type compounds as CRTH2 antagonists
US9290453B2 (en) 2010-12-23 2016-03-22 Merck Sharp & Dohme Corp. Quinolines and aza-quinolines as CRTH2 receptor modulators
WO2012087861A1 (en) 2010-12-23 2012-06-28 Merck Sharp & Dohme Corp. Quinoxalines and aza-quinoxalines as crth2 receptor modulators
EP3242664A4 (de) * 2015-01-09 2018-06-20 The Regents of the University of California Zusammensetzungen und verfahren zur behandlung von gastrointestinalen infektionen
CN108997177A (zh) * 2018-09-04 2018-12-14 邵阳学院 一种微波促进n-苯磺酰基硝基苯胺类化合物合成的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US430042A (en) * 1890-06-10 Valve
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
IL76839A (en) 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8505112D0 (sv) 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
US4758597A (en) 1987-05-15 1988-07-19 University Patents, Inc. Carenadiol and derivatives
US4965269A (en) 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5045522A (en) 1990-03-27 1991-09-03 Phillips Petroleum Company Absorption composition comprising zinc titanate for removal of hydrogen sulfide from fluid streams
AU649456B2 (en) 1990-06-20 1994-05-26 Astra Aktiebolag Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
SE9301830D0 (sv) 1993-05-28 1993-05-28 Ab Astra New compounds
CA2192202A1 (en) * 1994-06-10 1995-12-21 Bernhard Kohl Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria
US5708017A (en) 1995-04-04 1998-01-13 Merck & Co., Inc. Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors
US6093734A (en) 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
WO2000009498A1 (en) * 1998-08-10 2000-02-24 Partnership Of Michael E. Garst, George Sachs And Jai Moo Shin Prodrugs of proton pump inhibitors
RU2244712C2 (ru) * 1998-08-12 2005-01-20 Гайлид Сайенсиз, Инк. Способ получения 1,3-оксатиоланового нуклеозида, способ получения производного 1,3-оксатиоланил-5-она
SE0002476D0 (sv) 2000-06-30 2000-06-30 Astrazeneca Ab New compounds
US6599167B2 (en) 2000-09-27 2003-07-29 Glenn Waltz Game call holder and amplifying device
EP1334971A4 (de) * 2000-10-12 2004-05-12 Takeda Chemical Industries Ltd Benzimidazolverbindungen, verfahren zu deren herstellung und deren verwendung

Also Published As

Publication number Publication date
US20050143423A1 (en) 2005-06-30
AU2003259154A1 (en) 2004-02-09
US20040102484A1 (en) 2004-05-27
HK1079207A1 (en) 2006-03-31
WO2004009583A3 (en) 2004-03-18
AU2003259154B2 (en) 2006-12-07
WO2004009583A2 (en) 2004-01-29
DE60304726D1 (de) 2006-05-24
ZA200501116B (en) 2006-11-29
MXPA05000657A (es) 2005-08-19
DE60304726T2 (de) 2007-08-09
PL375255A1 (en) 2005-11-28
US6897227B2 (en) 2005-05-24
JP2005536519A (ja) 2005-12-02
BR0312802A (pt) 2005-04-19
CO5690576A2 (es) 2006-10-31
KR20070005029A (ko) 2007-01-09
ES2263028T3 (es) 2006-12-01
RU2292342C2 (ru) 2007-01-27
DK1556371T3 (da) 2006-08-21
AU2003259154C1 (en) 2004-02-09
EP1556371B1 (de) 2006-04-19
KR100788778B1 (ko) 2007-12-27
IL166371A0 (en) 2006-01-16
TW200502231A (en) 2005-01-16
CA2492718A1 (en) 2004-01-29
ATE323695T1 (de) 2006-05-15
KR20050047078A (ko) 2005-05-19
KR100822981B1 (ko) 2008-04-16
PT1556371E (pt) 2006-09-29
CA2492718C (en) 2010-12-21
JP4463103B2 (ja) 2010-05-12
RU2005105564A (ru) 2005-10-10
EP1556371A2 (de) 2005-07-27
NZ538221A (en) 2006-11-30
US20050182101A1 (en) 2005-08-18

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Legal Events

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