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NO20023749D0 - Kahalalid-forbindelser - Google Patents

Kahalalid-forbindelser

Info

Publication number
NO20023749D0
NO20023749D0 NO20023749A NO20023749A NO20023749D0 NO 20023749 D0 NO20023749 D0 NO 20023749D0 NO 20023749 A NO20023749 A NO 20023749A NO 20023749 A NO20023749 A NO 20023749A NO 20023749 D0 NO20023749 D0 NO 20023749D0
Authority
NO
Norway
Prior art keywords
kahalalide
kahalalide compounds
compounds
leads
preparing
Prior art date
Application number
NO20023749A
Other languages
English (en)
Other versions
NO20023749L (no
NO331847B1 (no
Inventor
Fernando Albericio
Ernest Giralt
Jose Carlos Jimenez
Angel Lopez
Ignacio Manzanares
Ignacio Rodrigues
Miriam Royo
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of NO20023749D0 publication Critical patent/NO20023749D0/no
Publication of NO20023749L publication Critical patent/NO20023749L/no
Publication of NO331847B1 publication Critical patent/NO331847B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K11/00Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Optical Record Carriers And Manufacture Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Detergent Compositions (AREA)
NO20023749A 2000-02-09 2002-08-08 Kahalalid-forbindelse, farmasoytisk preparat som omfatter forbindelsen, anvendelse av forbindelsen for fremstilling av et medikament for behandling av kreft og fremgangsmate for syntetisering av en forbindelse. NO331847B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0002952.0A GB0002952D0 (en) 2000-02-09 2000-02-09 Process for producing kahalalide F compounds
PCT/GB2001/000576 WO2001058934A2 (en) 2000-02-09 2001-02-09 Kahalalide f and related compounds

Publications (3)

Publication Number Publication Date
NO20023749D0 true NO20023749D0 (no) 2002-08-08
NO20023749L NO20023749L (no) 2002-10-07
NO331847B1 NO331847B1 (no) 2012-04-23

Family

ID=9885232

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20023749A NO331847B1 (no) 2000-02-09 2002-08-08 Kahalalid-forbindelse, farmasoytisk preparat som omfatter forbindelsen, anvendelse av forbindelsen for fremstilling av et medikament for behandling av kreft og fremgangsmate for syntetisering av en forbindelse.

Country Status (28)

Country Link
US (2) US7482429B2 (no)
EP (3) EP2258715A1 (no)
JP (1) JP5188665B2 (no)
KR (1) KR100871489B1 (no)
CN (2) CN101597326B (no)
AT (1) ATE371667T1 (no)
AU (1) AU783542B2 (no)
BG (1) BG65926B1 (no)
BR (1) BR0108213A (no)
CA (1) CA2399187C (no)
CY (1) CY1106992T1 (no)
CZ (1) CZ304258B6 (no)
DE (1) DE60130192T2 (no)
DK (1) DK1254162T3 (no)
ES (1) ES2292558T3 (no)
GB (1) GB0002952D0 (no)
HK (1) HK1047290A1 (no)
HU (1) HUP0301817A3 (no)
IL (2) IL150981A0 (no)
MX (1) MXPA02007760A (no)
NO (1) NO331847B1 (no)
NZ (1) NZ520488A (no)
PL (1) PL207121B1 (no)
PT (1) PT1254162E (no)
RU (1) RU2280039C2 (no)
SK (1) SK11242002A3 (no)
UA (1) UA76949C2 (no)
WO (1) WO2001058934A2 (no)

Families Citing this family (24)

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US6274551B1 (en) * 1994-02-03 2001-08-14 Pharmamar, S.A. Cytotoxic and antiviral compound
GB0002952D0 (en) * 2000-02-09 2000-03-29 Pharma Mar Sa Process for producing kahalalide F compounds
NZ525243A (en) 2000-10-31 2005-01-28 Pharma Mar S A lyophilised formulation comprising kahalalide F, a peptide isolated from a herbivorous marine species of mollusc, Elysia rufescens, to treat cancer
US20050054555A1 (en) * 2001-10-19 2005-03-10 Jose Jimeno Kahalalide compounds for use in cancer therapy
GB0304367D0 (en) * 2003-02-26 2003-04-02 Pharma Mar Sau Methods for treating psoriasis
US7507708B2 (en) 2003-02-26 2009-03-24 Pharma Mar, S.A.U. Antitumoral compounds
GB0321066D0 (en) * 2003-09-09 2003-10-08 Pharma Mar Sau New antitumoral compounds
GB0408958D0 (en) * 2004-04-22 2004-05-26 Pharma Mar Sa Convergent synthesis for kahalalide compounds
CN100396696C (zh) * 2004-04-23 2008-06-25 中国科学院海洋研究所 一种海洋绿藻在提取抗肿瘤活性环肽组分中的应用
JP2011500723A (ja) * 2007-10-19 2011-01-06 ファルマ・マール・ソシエダード・アノニマ 改善された抗腫瘍治療
AU2009209541A1 (en) * 2008-01-30 2009-08-06 Pharma Mar, S.A. Improved antitumoral treatments
US20110015135A1 (en) * 2008-03-07 2011-01-20 Pharma Mar S.A. Antitumoral Treatments
CN103641891B (zh) * 2013-05-23 2017-03-22 深圳翰宇药业股份有限公司 一种制备Kahalalide F的方法
CN108283000B (zh) 2015-09-23 2021-04-13 凯瑞康宁生物工程(武汉)有限公司 γ-羟基丁酸的前药及其组合物和用途
EP3601235A4 (en) 2017-03-30 2020-11-18 XW Laboratories Inc. BICYCLIC HETERARYL DERIVATIVES, PREPARATION AND ASSOCIATED USES
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
ES2947089T3 (es) 2018-09-30 2023-08-01 Xwpharma Ltd Compuestos como antagonistas del receptor histamínico 3 neuronal y usos de los mismos
CA3162919A1 (en) 2019-12-20 2021-06-24 XWPharma Ltd. Methods of synthesizing 4-valyloxybutyric acid
WO2021257832A1 (en) 2020-06-18 2021-12-23 XWPharma Ltd. Pharmaceutical granulations of water-soluble active pharmaceutical ingredients
KR20230011359A (ko) 2020-06-18 2023-01-20 엑스더블유파마 리미티드 수용성 활성 약제 성분의 제어 방출 과립화물
US11896573B2 (en) 2020-07-24 2024-02-13 XWPharma Ltd. Pharmaceutical compositions and pharmacokinetics of a gamma-hydroxybutyric acid derivative
CN115666527A (zh) 2020-10-05 2023-01-31 凯瑞康宁生物工程有限公司 γ-羟基丁酸衍生物的修饰释放组合物
JP2024511991A (ja) 2021-03-19 2024-03-18 エックスダブリューファーマ リミテッド ガンマ-ヒドロキシ酪酸誘導体の組み合わされた放出製剤の薬物動態
AU2023257266A1 (en) * 2022-04-21 2024-08-22 Zevra Therapeutics, Inc. Gamma-hydroxybutyrate delivering compounds and processes for making and using them

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US39496A (en) * 1863-08-11 Improvement in ratchet-drills
CU22545A1 (es) * 1994-11-18 1999-03-31 Centro Inmunologia Molecular Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico
US4943533A (en) * 1984-03-01 1990-07-24 The Regents Of The University Of California Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor
JPS6178719A (ja) 1984-09-25 1986-04-22 Tanabe Seiyaku Co Ltd 総合輸液剤
GR870129B (en) * 1987-01-27 1987-02-04 Giatzidis Ippokratis Stable bicarbonate - glycylglycine dialysate for hemodialysis and peritoneal dialysis
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
WO1992015683A1 (en) * 1991-03-06 1992-09-17 MERCK Patent Gesellschaft mit beschränkter Haftung Humanized and chimeric monoclonal antibodies
US5849704A (en) 1991-12-20 1998-12-15 Novo Nordisk A/S Pharmaceutical formulation
AU661533B2 (en) * 1992-01-20 1995-07-27 Astrazeneca Ab Quinazoline derivatives
US6274551B1 (en) * 1994-02-03 2001-08-14 Pharmamar, S.A. Cytotoxic and antiviral compound
GB9302046D0 (en) * 1993-02-03 1993-03-24 Pharma Mar Sa Antiumoral compound-v
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
US5705511A (en) 1994-10-14 1998-01-06 Cephalon, Inc. Fused pyrrolocarbazoles
GB9508538D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivatives
US5747498A (en) * 1996-05-28 1998-05-05 Pfizer Inc. Alkynyl and azido-substituted 4-anilinoquinazolines
JP3927248B2 (ja) 1995-07-11 2007-06-06 第一製薬株式会社 Hgf凍結乾燥製剤
PT912559E (pt) * 1996-07-13 2003-03-31 Glaxo Group Ltd Compostos heterociclicos fundidos como inibidores de proteina tirosina quinase
US6235883B1 (en) * 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
AU7476198A (en) * 1997-05-09 1998-11-27 General Hospital Corporation, The Cell proliferation related genes
RS49779B (sr) * 1998-01-12 2008-06-05 Glaxo Group Limited, Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
GB9803448D0 (en) 1998-02-18 1998-04-15 Pharma Mar Sa Pharmaceutical formulation
US6200598B1 (en) * 1998-06-18 2001-03-13 Duke University Temperature-sensitive liposomal formulation
HUP0104211A3 (en) * 1998-11-19 2003-01-28 Warner Lambert Co N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide, an irreversible inhibitor of tyrosine kinases and pharmaceutical composition containing it
US7311924B2 (en) * 1999-04-01 2007-12-25 Hana Biosciences, Inc. Compositions and methods for treating cancer
UA74803C2 (uk) * 1999-11-11 2006-02-15 Осі Фармасьютікалз, Інк. Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
GB0002952D0 (en) * 2000-02-09 2000-03-29 Pharma Mar Sa Process for producing kahalalide F compounds
AU5557501A (en) * 2000-04-28 2001-11-12 Univ Pennsylvania Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids
US6440465B1 (en) * 2000-05-01 2002-08-27 Bioderm, Inc. Topical composition for the treatment of psoriasis and related skin disorders
NZ525243A (en) 2000-10-31 2005-01-28 Pharma Mar S A lyophilised formulation comprising kahalalide F, a peptide isolated from a herbivorous marine species of mollusc, Elysia rufescens, to treat cancer
US20050054555A1 (en) 2001-10-19 2005-03-10 Jose Jimeno Kahalalide compounds for use in cancer therapy
GB0304367D0 (en) 2003-02-26 2003-04-02 Pharma Mar Sau Methods for treating psoriasis
US7507708B2 (en) * 2003-02-26 2009-03-24 Pharma Mar, S.A.U. Antitumoral compounds
GB0321066D0 (en) * 2003-09-09 2003-10-08 Pharma Mar Sau New antitumoral compounds
GB0408958D0 (en) * 2004-04-22 2004-05-26 Pharma Mar Sa Convergent synthesis for kahalalide compounds

Also Published As

Publication number Publication date
EP1829889A3 (en) 2007-09-26
CY1106992T1 (el) 2012-09-26
AU3208601A (en) 2001-08-20
NO20023749L (no) 2002-10-07
DE60130192T2 (de) 2008-05-21
JP5188665B2 (ja) 2013-04-24
DE60130192D1 (de) 2007-10-11
CN101597326B (zh) 2014-07-09
HUP0301817A3 (en) 2011-10-28
CN1422278A (zh) 2003-06-04
IL150981A (en) 2013-05-30
WO2001058934A3 (en) 2002-03-21
WO2001058934A2 (en) 2001-08-16
PT1254162E (pt) 2007-12-03
EP2258715A1 (en) 2010-12-08
RU2280039C2 (ru) 2006-07-20
NZ520488A (en) 2005-03-24
CA2399187A1 (en) 2001-08-16
NO331847B1 (no) 2012-04-23
HK1047290A1 (en) 2003-02-14
CZ304258B6 (cs) 2014-02-05
CA2399187C (en) 2011-04-19
KR20020092951A (ko) 2002-12-12
PL207121B1 (pl) 2010-11-30
AU783542B2 (en) 2005-11-10
JP2003522198A (ja) 2003-07-22
BG107020A (bg) 2003-05-30
UA76949C2 (en) 2006-10-16
BR0108213A (pt) 2003-03-05
BG65926B1 (bg) 2010-05-31
MXPA02007760A (es) 2002-10-23
US7482429B2 (en) 2009-01-27
RU2002123877A (ru) 2004-01-10
ES2292558T3 (es) 2008-03-16
GB0002952D0 (en) 2000-03-29
HUP0301817A2 (hu) 2003-09-29
CZ20022740A3 (cs) 2003-01-15
KR100871489B1 (ko) 2008-12-05
EP1829889A2 (en) 2007-09-05
ATE371667T1 (de) 2007-09-15
EP1254162B1 (en) 2007-08-29
US20080318849A1 (en) 2008-12-25
CN101597326A (zh) 2009-12-09
SK11242002A3 (sk) 2003-06-03
PL356800A1 (en) 2004-07-12
IL150981A0 (en) 2003-02-12
US20040214755A1 (en) 2004-10-28
EP1254162A2 (en) 2002-11-06
DK1254162T3 (da) 2008-01-02

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