MX9201365A - Derivados del indol novedosos, procedimientos de preparacion y medicamentos que los contienen. - Google Patents
Derivados del indol novedosos, procedimientos de preparacion y medicamentos que los contienen.Info
- Publication number
- MX9201365A MX9201365A MX9201365A MX9201365A MX9201365A MX 9201365 A MX9201365 A MX 9201365A MX 9201365 A MX9201365 A MX 9201365A MX 9201365 A MX9201365 A MX 9201365A MX 9201365 A MX9201365 A MX 9201365A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- alkylamino
- phenyl
- benzyl
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9103618A FR2674522B1 (fr) | 1991-03-26 | 1991-03-26 | Nouveaux derives de l'indole, procedes de preparation et medicaments les contenant. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9201365A true MX9201365A (es) | 1992-10-01 |
Family
ID=9411107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9201365A MX9201365A (es) | 1991-03-26 | 1992-03-26 | Derivados del indol novedosos, procedimientos de preparacion y medicamentos que los contienen. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5219859A (es) |
| EP (1) | EP0506532B1 (es) |
| JP (1) | JPH0597802A (es) |
| KR (1) | KR950007753B1 (es) |
| AT (1) | ATE111078T1 (es) |
| AU (1) | AU658609B2 (es) |
| CA (1) | CA2063170A1 (es) |
| CS (1) | CS89592A3 (es) |
| DE (1) | DE69200378T2 (es) |
| DK (1) | DK0506532T3 (es) |
| ES (1) | ES2064149T3 (es) |
| FR (1) | FR2674522B1 (es) |
| HU (1) | HUT65489A (es) |
| IE (1) | IE65366B1 (es) |
| IL (1) | IL101248A (es) |
| MA (1) | MA22474A1 (es) |
| MX (1) | MX9201365A (es) |
| NO (1) | NO178260C (es) |
| NZ (1) | NZ242078A (es) |
| OA (1) | OA09573A (es) |
| RU (1) | RU2074179C1 (es) |
| SI (1) | SI9210305A (es) |
| TN (1) | TNSN92022A1 (es) |
| YU (1) | YU30592A (es) |
| ZA (1) | ZA922163B (es) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2687402B1 (fr) * | 1992-02-14 | 1995-06-30 | Lipha | Nouveaux azaindoles, procedes de preparation et medicaments les contenant. |
| BR9306421A (pt) * | 1992-05-28 | 1998-09-15 | Pfizer | Novos derivados n-aril e n-heteroariluréia como inbidores da acilcoenzima a:colesterol aciltransferase (acat) |
| NZ250916A (en) * | 1993-02-27 | 1995-08-28 | Nihon Nohyaku Co Ltd | N-heteroaryl-n'-phenylureas, their use as acat inhibitors |
| IL109568A0 (en) * | 1993-05-19 | 1994-08-26 | Fujisawa Pharmaceutical Co | Urea derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
| DE4401893A1 (de) * | 1994-01-24 | 1995-07-27 | Bayer Ag | Substituierte Arylharnstoffe |
| JP3720395B2 (ja) * | 1994-09-20 | 2005-11-24 | 京都薬品工業株式会社 | 新規ヘテロ環誘導体、その製造方法およびその医薬用途 |
| ATE206702T1 (de) * | 1995-06-06 | 2001-10-15 | Pfizer | Substituierte n-(indol-2-carbonyl)-glycinamide und derivate als glycogen phosphorylase inhibitoren |
| MY114711A (en) * | 1995-06-06 | 2002-12-31 | Pfizer | Substituted n-(indole-2-carbonyl)-b-alanmamides and derivatives as antidiabetic agents |
| ES2161291T3 (es) | 1995-06-06 | 2001-12-01 | Pfizer | N-(indol-2-carbonil)amidas y derivados como inhibidores de la glucogeno fosforilasa. |
| AU679887B2 (en) * | 1995-09-11 | 1997-07-10 | Nihon Nohyaku Co., Ltd. | Azole derivatives, their use, production and usage |
| DE69617731T2 (de) * | 1995-10-05 | 2002-08-08 | Kyoto Pharmaceutical Industries, Ltd. | Neue heterozyklische derivate und ihre medizinische anwendung |
| CA2190041A1 (en) * | 1995-11-13 | 1997-05-14 | Shinya Inoue | Urea derivatives |
| FR2763334A1 (fr) * | 1997-05-13 | 1998-11-20 | Lipha | Derives anthraniliques |
| PT1047678E (pt) * | 1997-12-16 | 2004-12-31 | Warner Lambert Co | Derivados do 1-aminometil-cicloalcano substituido em 1 (=analogos da gabapentina) sua preparacao e sua utilizacao no tratamento de disturbios neurologicos |
| PL341231A1 (en) * | 1997-12-16 | 2001-03-26 | Warner Lambert Co | 4(3)-substitute derivatives of 4(3)aminomethyl(thio)pyrane or piperidine derivatives (analogues of garbapentin), their production and application in treating neurological disorders |
| WO1999031074A2 (en) * | 1997-12-16 | 1999-06-24 | Warner-Lambert Company | ((cyclo)alkyl substituted)-.gamma.-aminobutyric acid derivatives (=gaba analogues), their preparation and their use in the treatment of neurological disorders |
| SK282727B6 (sk) | 1997-12-19 | 2002-11-06 | Slovakofarma, A. S. | 1,3-Disubstituované močoviny - inhibítory ACAT a spôsob ich prípravy |
| US6277877B1 (en) | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
| US7153882B2 (en) | 2000-11-02 | 2006-12-26 | The United States Of America As Represented By The Department Of Health And Human Services | Agents useful for reducing amyloid precursor protein and treating demantia and methods of use thereof |
| BR0309764A (pt) * | 2002-05-03 | 2005-02-15 | Warner Lambert Co | Antagonistas de bombesina |
| EP1541553B1 (en) * | 2002-07-17 | 2010-06-02 | Kyoto Pharmaceutical Industries, Ltd. | Indoline compound and medicinal use thereof |
| US7595403B2 (en) | 2003-04-01 | 2009-09-29 | Eli Lilly And Company | Benzisothiazol-3-one-carboxylic acid amides as phospholipase inhibitors |
| CN101321752A (zh) | 2005-11-30 | 2008-12-10 | 弗·哈夫曼-拉罗切有限公司 | 3-氨基-2-芳基丙基氮杂吲哚及其应用 |
| BRPI0619263A2 (pt) | 2005-11-30 | 2011-09-27 | Hoffmann La Roche | indóis de 3-amino-1-arilpropila e indóis aza-substituìdos, métodos para prepará-los, composição farmacêutica e uso dos referidos indóis |
| RU2361581C2 (ru) * | 2007-09-14 | 2009-07-20 | Закрытое Акционерное Общество "Мастерклон" | Фармацевтическая композиция, обладающая противодиабетической, гиполипидемической, гипогликемической и гипохолестеринемической активностью, способ ее получения и способы лечения указанных заболеваний |
| SK287385B6 (sk) | 2007-11-27 | 2010-08-09 | Hameln-Rds, A. S. | 1,3-Disubstituované močoviny, spôsob ich prípravy a použitia |
| CN104628621A (zh) * | 2015-01-22 | 2015-05-20 | 湖南华腾制药有限公司 | 一种氟取代吲哚衍生物的制备方法 |
| CN110913854B (zh) | 2017-06-26 | 2023-04-28 | 卢内拉生物技术有限公司 | mitoketoscin：靶向癌细胞中酮代谢的基于线粒体的治疗剂 |
| JP2022521789A (ja) | 2019-02-27 | 2022-04-12 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 脳障害を治療するためのアゼピノ－インドール及び他の複素環化合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55151505A (en) * | 1979-05-14 | 1980-11-26 | Kuraray Co Ltd | Indole agricultural and horticultural fungicide |
| IL85189A (en) * | 1987-02-02 | 1992-06-21 | Lilly Co Eli | Beta-alkyl substituted melatonins,their preparation and pharmaceutical compositions containing them |
| EP0375133A1 (en) * | 1988-11-14 | 1990-06-27 | The Upjohn Company | Alpha-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents |
| IL95584A (en) * | 1989-09-07 | 1995-03-15 | Abbott Lab | Indole-, benzoporene- and benzothiophene compounds including lipoxygenase-inhibiting compounds and pharmaceutical compounds containing them |
| MX22406A (es) * | 1989-09-15 | 1994-01-31 | Pfizer | Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat). |
| ES2079530T3 (es) * | 1990-08-13 | 1996-01-16 | Hoechst Roussel Pharma | 1-(piridinilalquil)-1h-indoles, -indolinas y compuestos analogos relacionados. |
| FR2680366B1 (fr) * | 1991-08-13 | 1995-01-20 | Adir | Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| WO1993005020A1 (en) * | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
-
1991
- 1991-03-26 FR FR9103618A patent/FR2674522B1/fr not_active Expired - Fee Related
-
1992
- 1992-03-16 IL IL10124892A patent/IL101248A/en not_active IP Right Cessation
- 1992-03-17 CA CA002063170A patent/CA2063170A1/en not_active Abandoned
- 1992-03-20 DE DE69200378T patent/DE69200378T2/de not_active Expired - Fee Related
- 1992-03-20 EP EP92400764A patent/EP0506532B1/fr not_active Expired - Lifetime
- 1992-03-20 AU AU13094/92A patent/AU658609B2/en not_active Ceased
- 1992-03-20 NZ NZ242078A patent/NZ242078A/en unknown
- 1992-03-20 ES ES92400764T patent/ES2064149T3/es not_active Expired - Lifetime
- 1992-03-20 DK DK92400764.4T patent/DK0506532T3/da active
- 1992-03-20 US US07/855,544 patent/US5219859A/en not_active Expired - Fee Related
- 1992-03-20 AT AT92400764T patent/ATE111078T1/de active
- 1992-03-23 MA MA22763A patent/MA22474A1/fr unknown
- 1992-03-24 NO NO921141A patent/NO178260C/no unknown
- 1992-03-24 IE IE920937A patent/IE65366B1/en not_active IP Right Cessation
- 1992-03-25 JP JP4067252A patent/JPH0597802A/ja active Pending
- 1992-03-25 RU SU925011235A patent/RU2074179C1/ru active
- 1992-03-25 CS CS92895A patent/CS89592A3/cs unknown
- 1992-03-25 ZA ZA922163A patent/ZA922163B/xx unknown
- 1992-03-25 HU HU9200997A patent/HUT65489A/hu unknown
- 1992-03-26 MX MX9201365A patent/MX9201365A/es not_active IP Right Cessation
- 1992-03-26 YU YU30592A patent/YU30592A/sh unknown
- 1992-03-26 SI SI9210305A patent/SI9210305A/sl unknown
- 1992-03-26 TN TNTNSN92022A patent/TNSN92022A1/fr unknown
- 1992-03-26 OA OA60177A patent/OA09573A/fr unknown
- 1992-03-26 KR KR1019920005020A patent/KR950007753B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO178260C (no) | 1996-02-21 |
| AU658609B2 (en) | 1995-04-27 |
| DE69200378T2 (de) | 1995-03-09 |
| OA09573A (fr) | 1993-01-31 |
| MA22474A1 (fr) | 1992-10-01 |
| SI9210305A (en) | 1996-02-29 |
| ZA922163B (en) | 1993-09-27 |
| FR2674522A1 (fr) | 1992-10-02 |
| IL101248A0 (en) | 1992-11-15 |
| YU30592A (sh) | 1994-12-28 |
| EP0506532A1 (fr) | 1992-09-30 |
| RU2074179C1 (ru) | 1997-02-27 |
| FR2674522B1 (fr) | 1993-07-16 |
| AU1309492A (en) | 1992-10-01 |
| ATE111078T1 (de) | 1994-09-15 |
| IL101248A (en) | 1996-12-05 |
| KR920018022A (ko) | 1992-10-21 |
| KR950007753B1 (ko) | 1995-07-14 |
| DE69200378D1 (de) | 1994-10-13 |
| NO921141D0 (no) | 1992-03-24 |
| US5219859A (en) | 1993-06-15 |
| NZ242078A (en) | 1994-10-26 |
| TNSN92022A1 (fr) | 1993-06-08 |
| HUT65489A (en) | 1994-06-28 |
| DK0506532T3 (da) | 1995-02-20 |
| IE920937A1 (en) | 1992-10-07 |
| NO178260B (no) | 1995-11-13 |
| CS89592A3 (en) | 1992-10-14 |
| HU9200997D0 (en) | 1992-05-28 |
| CA2063170A1 (en) | 1992-09-27 |
| ES2064149T3 (es) | 1995-01-16 |
| EP0506532B1 (fr) | 1994-09-07 |
| JPH0597802A (ja) | 1993-04-20 |
| NO921141L (no) | 1992-09-28 |
| IE65366B1 (en) | 1995-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |