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ME00681B - Jedinjenje indola - Google Patents

Jedinjenje indola

Info

Publication number
ME00681B
ME00681B MEP-2009-118A MEP11809A ME00681B ME 00681 B ME00681 B ME 00681B ME P11809 A MEP11809 A ME P11809A ME 00681 B ME00681 B ME 00681B
Authority
ME
Montenegro
Prior art keywords
indole compound
present
glucokinase activator
prodrug
prophylaxis
Prior art date
Application number
MEP-2009-118A
Other languages
English (en)
French (fr)
Inventor
Tsuneo Yasuma
Osamu Ujikawa
Masahiro Itoh
Kazuko Aoki
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39010108&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME00681(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of MEP11809A publication Critical patent/MEP11809A/xx
Publication of ME00681B publication Critical patent/ME00681B/me

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433Thidiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)

Abstract

Svrha ovog pronalaska je da obezbedi aktivator glukokinaze koristan kao farmaceutsko sredstvo kao što je sredstvo za profilaksu ili tretman dijabetesa, gojaznosti i slično. Ovaj pronalazak obezbeđuje aktivator glukokinaze koji sadrži jedinjenje predstavljeno formulom (I):   gde R 1  je atom vodonika ili atom halogena; R 2  je grupa predstavljena sa   gde je svaki simbol definisan u specifikaciji, ili njegovu so ili njegov prolek.  
MEP-2009-118A 2006-10-19 2007-10-18 Jedinjenje indola ME00681B (me)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006285551 2006-10-19
PCT/JP2007/070772 WO2008050821A1 (en) 2006-10-19 2007-10-18 Indole compound

Publications (2)

Publication Number Publication Date
MEP11809A MEP11809A (en) 2011-12-20
ME00681B true ME00681B (me) 2011-12-20

Family

ID=39010108

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2009-118A ME00681B (me) 2006-10-19 2007-10-18 Jedinjenje indola

Country Status (26)

Country Link
US (4) US8410087B2 (me)
EP (2) EP2508524A3 (me)
JP (1) JP5260507B2 (me)
KR (1) KR101444486B1 (me)
CN (1) CN101573357B (me)
AU (1) AU2007310064B2 (me)
BR (1) BRPI0717722A2 (me)
CA (1) CA2666973C (me)
CL (1) CL2008001017A1 (me)
CR (1) CR10748A (me)
EC (1) ECSP099330A (me)
GE (1) GEP20115241B (me)
IL (1) IL198154A (me)
MA (1) MA30890B1 (me)
ME (1) ME00681B (me)
MX (1) MX2009003972A (me)
MY (1) MY158052A (me)
NO (1) NO20091948L (me)
NZ (1) NZ576570A (me)
PE (1) PE20090884A1 (me)
RU (1) RU2454415C9 (me)
TN (1) TN2009000129A1 (me)
TW (1) TWI460176B (me)
UA (1) UA97257C2 (me)
WO (1) WO2008050821A1 (me)
ZA (1) ZA200902585B (me)

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JP5364103B2 (ja) * 2007-12-20 2013-12-11 エルジー・ライフ・サイエンシーズ・リミテッド グルコキナーゼ活性化剤およびそれを活性成分として含有する医薬組成物
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Also Published As

Publication number Publication date
PE20090884A1 (es) 2009-08-05
KR20090068292A (ko) 2009-06-25
CN101573357B (zh) 2013-01-23
AU2007310064A1 (en) 2008-05-02
AU2007310064A2 (en) 2009-06-04
US20080096877A1 (en) 2008-04-24
NZ576570A (en) 2010-11-26
MA30890B1 (fr) 2009-11-02
JP2010506825A (ja) 2010-03-04
JP5260507B2 (ja) 2013-08-14
EP2508524A2 (en) 2012-10-10
CA2666973A1 (en) 2008-05-02
KR101444486B1 (ko) 2014-09-24
NO20091948L (no) 2009-07-13
US20100144702A1 (en) 2010-06-10
US7718798B2 (en) 2010-05-18
CA2666973C (en) 2015-03-31
CR10748A (es) 2009-05-20
US20100137610A1 (en) 2010-06-03
TW200825071A (en) 2008-06-16
CL2008001017A1 (es) 2009-04-24
IL198154A (en) 2014-08-31
TN2009000129A1 (en) 2010-10-18
BRPI0717722A2 (pt) 2013-10-29
US7777047B2 (en) 2010-08-17
IL198154A0 (en) 2009-12-24
RU2454415C9 (ru) 2013-02-27
ZA200902585B (en) 2010-09-29
EP2074119A1 (en) 2009-07-01
EP2508524A3 (en) 2012-10-24
CN101573357A (zh) 2009-11-04
UA97257C2 (en) 2012-01-25
MEP11809A (en) 2011-12-20
RU2009118602A (ru) 2010-11-27
US7652133B2 (en) 2010-01-26
WO2008050821A1 (en) 2008-05-02
RU2454415C2 (ru) 2012-06-27
MY158052A (en) 2016-08-30
TWI460176B (zh) 2014-11-11
US8410087B2 (en) 2013-04-02
AU2007310064B2 (en) 2013-03-28
US20090286975A1 (en) 2009-11-19
ECSP099330A (es) 2009-06-30
GEP20115241B (en) 2011-06-10
MX2009003972A (es) 2009-04-27

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