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MA49906A - Acides aminés à chaîne ramifiée pour le traitement d'une maladie du foie - Google Patents

Acides aminés à chaîne ramifiée pour le traitement d'une maladie du foie

Info

Publication number
MA49906A
MA49906A MA049906A MA49906A MA49906A MA 49906 A MA49906 A MA 49906A MA 049906 A MA049906 A MA 049906A MA 49906 A MA49906 A MA 49906A MA 49906 A MA49906 A MA 49906A
Authority
MA
Morocco
Prior art keywords
branched
treatment
amino acids
liver disease
chain amino
Prior art date
Application number
MA049906A
Other languages
English (en)
Inventor
Raffi Afeyan
Sean Carroll
William Comb
Michael Hamill
Original Assignee
Axcella Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axcella Health Inc filed Critical Axcella Health Inc
Publication of MA49906A publication Critical patent/MA49906A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
MA049906A 2017-08-14 2018-08-14 Acides aminés à chaîne ramifiée pour le traitement d'une maladie du foie MA49906A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762545362P 2017-08-14 2017-08-14
US201862614214P 2018-01-05 2018-01-05
US201862697772P 2018-07-13 2018-07-13

Publications (1)

Publication Number Publication Date
MA49906A true MA49906A (fr) 2020-06-24

Family

ID=63449706

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049906A MA49906A (fr) 2017-08-14 2018-08-14 Acides aminés à chaîne ramifiée pour le traitement d'une maladie du foie

Country Status (22)

Country Link
US (3) US10682325B2 (fr)
EP (1) EP3668499A1 (fr)
JP (2) JP7266581B2 (fr)
KR (1) KR20200039748A (fr)
CN (1) CN111295187A (fr)
AU (1) AU2018318112A1 (fr)
BR (1) BR112020002419A2 (fr)
CA (1) CA3070856A1 (fr)
CL (1) CL2020000382A1 (fr)
CO (1) CO2020001702A2 (fr)
CU (1) CU20200012A7 (fr)
EC (1) ECSP20011578A (fr)
IL (3) IL296055A (fr)
JO (1) JOP20200033A1 (fr)
MA (1) MA49906A (fr)
MX (1) MX2020001765A (fr)
PE (1) PE20200747A1 (fr)
PH (1) PH12020500321A1 (fr)
SG (1) SG11202001142VA (fr)
TW (1) TWI775921B (fr)
WO (1) WO2019036471A1 (fr)
ZA (1) ZA202000725B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
US11617731B2 (en) 2017-04-28 2023-04-04 Axcella Health, Inc. Amino acid compositions and their use for the treatment of traumatic brain injury
JOP20200033A1 (ar) 2017-08-14 2020-02-13 Axcella Health Inc تركيبات حمض أميني لمعالجة مرض كبدي
WO2019246201A1 (fr) 2018-06-20 2019-12-26 Axcella Health Inc. Procédés de fabrication de compositions d'acides aminés
CU20200106A7 (es) 2018-06-20 2021-08-06 Axcella Health Inc Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias
EP3810123A1 (fr) * 2018-06-20 2021-04-28 Axcella Health Inc. Compositions et procédés pour le traitement de l'infiltration de graisse dans le muscle
WO2021060884A1 (fr) * 2019-09-24 2021-04-01 마이오텍사이언스 주식회사 Composition pharmaceutique pour la prévention ou le traitement de la sarcopénie contenant un dérivé d'acide aminé non naturel
US20230105984A1 (en) * 2019-12-23 2023-04-06 Svetlana Marukian Compositions and methods for the treatment of liver diseases and disorders
EP4081205A1 (fr) 2019-12-23 2022-11-02 Axcella Health Inc. Compositions et procédés comprenant des acides aminés pour le traitement d'infiltrations de graisse dans le muscle
CN111602817A (zh) * 2020-05-19 2020-09-01 西安交通大学医学院第一附属医院 一种用于防治肝性肌少症的膳食组合物及其制备方法
US20230117618A1 (en) * 2021-10-19 2023-04-20 Johnson Consulting, LLC Oral Supplement to Trigger Repair Of Organs

Family Cites Families (325)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US693094A (en) 1900-08-13 1902-02-11 Hall Signal Co Signal and signaling-circuit.
US2457820A (en) 1945-12-27 1949-01-04 Merck & Co Inc Amino acid solution and process for preparing the same
GB1034358A (en) 1963-05-01 1966-06-29 Chugai Pharmaceutical Co Ltd Body-protein-biosynthesis promoting composition
US3832465A (en) 1971-12-09 1974-08-27 H Ghadimi Injectable amino acid composition commensurate to the anabolic need of the body and method of using same
US3988466A (en) 1973-06-01 1976-10-26 Kyowa Hakko Kogyo Co., Ltd. Prevention of gastric lesions
US3950529A (en) 1975-02-03 1976-04-13 Massachusetts General Hospital Amino acid formulations for patients with liver disease and method of using same
JPS5535049A (en) 1978-09-04 1980-03-11 Otsuka Pharmaceut Factory Inc Amino acid transfusion for cancerous patient
DE2906034C2 (de) 1979-02-16 1985-03-28 Maggi AG, Kempttal Verfahren zur Gewinnung von L-Leucin, L-Phenylalanin, L-Tyrosin, L-Cystin und von Gemischen aus L-Leucin und L-Isoleucin
CA1184499A (fr) 1981-06-29 1985-03-26 David C. Madsen Compose nutritif pour le traitement de l'insuffisance hepatique
US4898879A (en) 1981-06-29 1990-02-06 Baxter International Inc. Nurtitional composition for management of hepatic failure
JPS58126767A (ja) 1982-01-22 1983-07-28 Ajinomoto Co Inc 肝臓病患者用栄養組成物
US5298493A (en) 1983-04-20 1994-03-29 Clintec Nutrition Co. Compound for use in dietetics, reanimation and therapeutics containing protein fractions based on three types of minipeptides
CH658165A5 (fr) 1984-01-04 1986-10-31 Nestle Sa Produit alimentaire efficace dans le traitement de la lepre.
US5034377A (en) 1984-11-19 1991-07-23 Montefiore Hospital Association Of Western Pennsylvania Aqueous nutrient compositions comprising oligopeptides
US4871550A (en) 1986-09-05 1989-10-03 Millman Phillip L Nutrient composition for athletes and method of making and using the same
FR2618331B1 (fr) 1987-07-23 1991-10-04 Synthelabo Compositions pharmaceutiques utiles pour le traitement de l'uremie
US5028622A (en) 1988-05-06 1991-07-02 Ajinomoto Company, Inc. Administration of amino acids as treatment for neurodegenerative disorders
US5576351A (en) 1989-12-29 1996-11-19 Mcgaw, Inc. Use of arginine as an immunostimulator
EP0486425B1 (fr) 1990-11-01 1994-08-31 Sandoz Nutrition Ltd. Formules nitritives comprenant un système fortement acide
US5106836A (en) 1991-02-22 1992-04-21 Clintec Nutrition Co. Enteral diet
US5977073A (en) 1991-06-06 1999-11-02 Life Sciences' Technologies, Inc. Nutrient composition for treatment of immune disorders
US5780039A (en) 1992-04-23 1998-07-14 Novartis Nutrition Ag Orally-ingestible nutrition compositions having improved palatability
US5229136A (en) 1992-05-21 1993-07-20 Clintec Nutrition Co. Low caloric density enteral formulation designed to reduce diarrhea in tube-fed patients
US5276018A (en) 1992-07-17 1994-01-04 Brigham And Women's Hospital Composition comprising amino acids and methods for decreasing muscle breakdown
DE4229166A1 (de) 1992-09-01 1994-03-03 Deutsches Krebsforsch Mittel zur Aufrechterhaltung und/oder Steigerung der Muskelleistung und Körperzellmasse
US5356873A (en) 1992-11-05 1994-10-18 Clintec Nutrition Co. Method for providing nutritional requirements to patients having a chronic inflammation reaction
AU679020B2 (en) 1992-12-23 1997-06-19 Abbott Laboratories Medical foods for the nutritional support of infant/toddler metabolic diseases
US5348979A (en) 1992-12-23 1994-09-20 Iowa State University Research Foundation Inc. Method of promoting nitrogen retention in humans
US5571783A (en) 1993-03-09 1996-11-05 Clintec Nutrition Company Composition and method for treating patients with hepatic disease
US5891459A (en) 1993-06-11 1999-04-06 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
WO1995004529A1 (fr) 1993-08-10 1995-02-16 Musashi Pty. Ltd. Composition pour le traitement des effets resultant d'un abus d'alcool
US5438042B1 (en) 1993-10-08 1997-08-26 Sandoz Nutrition Ltd Enteral nutritional composition having amino acid profile
AU682894B2 (en) 1993-10-28 1997-10-23 Institut National De La Recherche Agronomique Composition based on amino acids intended for the treatment of sepsis or of an attack bringing about an inflammatory reaction, in animals and man
US5378722A (en) 1993-12-03 1995-01-03 Clintec Nutrition Co. Nutritional compositions for management of nitrogen metabolism
US5714472A (en) 1993-12-23 1998-02-03 Nestec Ltd. Enternal formulation designed for optimized nutrient absorption and wound healing
US5723446A (en) 1993-12-23 1998-03-03 Nestec Ltd. Enteral formulation designed for optimized nutrient absorption and wound healing
GB9403935D0 (en) 1994-03-01 1994-04-20 Sandoz Nutrition Ltd Improvements in or relating to organic compounds
US5719133A (en) 1994-09-21 1998-02-17 Novartis Nutrition Ag Adolescent dietary composition
IT1275434B (it) 1995-05-19 1997-08-07 Farmila Farma Milano Composizioni farmaceutiche e/o dietetiche ad attivita' antiossidante
US5728678A (en) 1995-06-06 1998-03-17 Nestec Ltd. Method and composition for providing nutrition to a renal failure patient
JP4280310B2 (ja) 1995-08-10 2009-06-17 佐々木化学工業株式会社 アミノ酸組成剤
US5733884A (en) 1995-11-07 1998-03-31 Nestec Ltd. Enteral formulation designed for optimized wound healing
US6087398A (en) 1996-03-01 2000-07-11 South Alabama Medical Science Foundation Sickle cell anemia treatment
US5716926A (en) * 1996-07-26 1998-02-10 Paxton K. Beale Composition of pyruvate and protein and method for increasing protein concentration in a mammal
US6096785A (en) 1996-07-30 2000-08-01 Novartis Nutrition Ag Amino acid compositions and use thereof in treating renal dysfunction
JPH1053521A (ja) 1996-08-12 1998-02-24 Kagaku Gijutsu Shinko Jigyodan 脳内グルタミン酸の活性抑制剤および活性増強剤
IT1289754B1 (it) 1996-12-16 1998-10-16 Professional Dietetics Srl Composizioni a base di aminoacidi
US6013273A (en) 1997-01-27 2000-01-11 Novartis Nutrition Ag Treatment of endotoxic shock
US5817329A (en) 1997-02-28 1998-10-06 Gardiner; Paul T. Nutritional supplement for increased muscle size and strength for body builders
US5849335A (en) 1997-06-02 1998-12-15 Nestec S.A. Composition and method for providing glutamine
EP1123013A1 (fr) 1997-06-02 2001-08-16 Société des Produits Nestlé S.A. Produit et procede d'apport de glutamine
EP0882451B1 (fr) 1997-06-05 2004-05-12 Novartis Nutrition AG Glycine pour la prévention ou le traitement du rejet de greffes
US6281244B1 (en) 1997-06-05 2001-08-28 Novartis Nutrition Ag Therapeutic use for glycine
EP0891719A1 (fr) 1997-07-14 1999-01-20 N.V. Nutricia Composition dietique contenant de la methionine
IT1294227B1 (it) 1997-08-01 1999-03-24 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione
TW473387B (en) 1997-09-30 2002-01-21 Chugai Pharmaceutical Co Ltd Pharmaceutical or food compositions for treating hepatic diseases or improving liver functions
US6288116B1 (en) 1998-05-13 2001-09-11 Novartis Nutrition Ag Method of administration of a nutritional product to a person having renal failure
US6203820B1 (en) 1998-05-28 2001-03-20 Brice E. Vickery Compositions and methods for enhancing protein anabolism and detoxification
US6103748A (en) 1998-06-19 2000-08-15 Bryan; Thomas B. Method of treating an autoimmune disorder
US6031000A (en) 1998-06-23 2000-02-29 Iowa State University Research Foundation, Inc. Composition comprising β-hydroxy-β-methylbutyric acid and at least one amino acid and methods of use
JP2000072669A (ja) 1998-08-24 2000-03-07 Inst Of Physical & Chemical Res アミノ酸・糖組成物
US6458338B1 (en) 1998-09-22 2002-10-01 Aeropharm Technology Incorporated Amino acid stabilized medicinal aerosol formulations
US20010041187A1 (en) 1998-10-20 2001-11-15 Carl W Hastings Performance-enhancing dietary supplement
EP1004302A3 (fr) 1998-10-29 2003-06-04 Ajinomoto Co., Inc. Immunomodulateur
US6051236A (en) 1998-11-12 2000-04-18 Pacifichealth Laboratories, Inc. Composition for optimizing muscle performance during exercise
US6143786A (en) 1999-02-02 2000-11-07 Novartis Nutrition Ag Oral arginine and insulin secretion
US6241996B1 (en) 1999-04-09 2001-06-05 Novartis Nutrition Ag Liquid soy nutritional products
CA2306720A1 (fr) 1999-04-27 2000-10-27 Philip White Pour retablir les niveaux d'hormone de croissance
AU8003800A (en) 1999-10-08 2001-04-23 Joyce Corinne Bechthold Methods and compositions for treating neurobehavioral disorders
GB9929497D0 (en) 1999-12-14 2000-02-09 Vitaflo Limited Improved amino acid mixtures for the treatment and/or management of certain diseases
RU2002122099A (ru) 2000-02-01 2004-08-10 МУСКЛЕТЕЧ РЕСиЧ ЭНД ДЕВЕЛОПМЕНТ ИНК. (CA) Пищевая добавка для увеличения мышечной массы и силы на основе альфа-липоевой кислоты
US6833350B2 (en) 2000-02-04 2004-12-21 Nestec S.A. Method for maintaining or improving the synthesis of mucins
US6521591B1 (en) 2000-02-10 2003-02-18 N.V. Nutricia Pharmaceutical composition for muscular anabolism
GB0009056D0 (en) 2000-04-12 2000-05-31 Nestle Sa Composition comprising free amino acids
US7794744B2 (en) 2000-04-18 2010-09-14 Nestec S.A. Nutritional modules
US6391332B1 (en) 2000-04-20 2002-05-21 Baxter International, Inc. Therapeutic micronutrient composition for severe trauma, burns and critical illness
US20030187049A1 (en) 2000-07-04 2003-10-02 Dioguardi Francesco Saverio Compositions based on aminoacids, suitable for improving muscle performance
IT1320782B1 (it) 2000-07-04 2003-12-10 Professional Dietetics Srl Composizioni a base di aminoacidi, atte al trattamentodell'insufficienza cardiaca.
IT1320783B1 (it) 2000-07-04 2003-12-10 Professional Dietetics Srl Composizioni a base di aminoacidi, atte al miglioramento delleprestazioni muscolari.
WO2002069964A1 (fr) 2001-03-05 2002-09-12 Ernest Stephen P Formulation enterale
EP1374863B1 (fr) 2001-03-15 2009-09-02 Riken Compositions d'acides amines utilisees pour ameliorer le malfonctionnement hepatique
US20020193342A1 (en) 2001-05-09 2002-12-19 Hamman John P. Modifying undesirable tastes
ITTO20010580A1 (it) 2001-06-15 2002-12-15 Professional Dietetics Srl Composizioni a base di aminoacidi per il miglioramento della funzioneventricolare miocardica in pazienti affetti da diabete.
US6864230B2 (en) 2001-07-31 2005-03-08 Novartis Nutrition Ag Glutamine rich dietary composition
EP1466602A4 (fr) 2001-12-25 2006-03-01 Ajinomoto Kk Inhibiteurs de fibrose des organes
EP1471903B1 (fr) 2002-01-25 2019-11-20 SciMar Ltd. Utilisation de composes stimulant la synthese du glutathion dans la reduction de la resistance a l'insuline
JP2003238401A (ja) 2002-02-20 2003-08-27 Ajinomoto Co Inc 疾患の治療、改善又は予防用医薬品及び飲食品
US7338675B2 (en) 2002-05-10 2008-03-04 Tsi Health Sciences, Inc. Fenugreek seed bio-active compositions and methods for extracting same
US20050176827A1 (en) 2002-05-10 2005-08-11 Lee Steve S. Compositions and methods for glycogen synthesis
EP1549299B1 (fr) 2002-06-05 2014-08-20 IVAX Pharmaceuticals s.r.o. Reduction de la reticulation de gelatine
EP1541141A1 (fr) 2002-08-30 2005-06-15 Ajinomoto Co., Inc. Agent pour le traitement des maladies hepatiques
US20040087490A1 (en) 2002-09-20 2004-05-06 Troup John P. Nutritional compositions
US20040057983A1 (en) 2002-09-25 2004-03-25 David Schmidt Biomolecular wearable apparatus
US7037522B2 (en) 2002-09-27 2006-05-02 Western Holdings, L.L.C. Nocturnal muscle enhancing composition and method
JP2004123564A (ja) 2002-09-30 2004-04-22 Inst Of Physical & Chemical Res 中枢機能改善用アミノ酸組成物
JP2004182705A (ja) 2002-10-11 2004-07-02 Yasutoshi Koga ミトコンドリア機能異常に起因する疾患における臨床症状発現の予防・治療用組成物
US7547450B2 (en) 2002-10-24 2009-06-16 Nestec Ltd. Senior feline food
US8093292B2 (en) 2002-11-22 2012-01-10 Bionexus, Ltd. Methods for the treatment of HIV-1 related fat maldistribution, fasting hyperlipidemia and modification of adipocyte physiology
US7288570B2 (en) 2002-12-20 2007-10-30 Nutricia N.V. Stimulation of in vivo production of proteins
US20040120983A1 (en) 2002-12-23 2004-06-24 Philip Connolly Nutritional supplement
JP4989836B2 (ja) 2002-12-26 2012-08-01 大塚製薬株式会社 経口栄養剤
KR20110120981A (ko) 2002-12-26 2011-11-04 아지노모토 가부시키가이샤 간암 발생 및 진행 억제제
PL377614A1 (pl) 2003-03-18 2006-02-06 Novartis Ag Kompozycje zawierające kwasy tłuszczowe i aminokwasy
US20040213838A1 (en) 2003-04-24 2004-10-28 Mazer Terrence B. Medical food tablets containing free amino acids
JP4528925B2 (ja) 2003-05-30 2010-08-25 独立行政法人理化学研究所 アミノ酸組成物及び補液
ES2391558T3 (es) 2003-06-23 2012-11-27 Nestec S.A. Suplemento de aminoácidos para un ecosistema microbiótico sano
JP2005027524A (ja) 2003-07-08 2005-02-03 Ajinomoto Co Inc 経口アミノ酸組成物
WO2005017094A2 (fr) 2003-08-19 2005-02-24 Bioadvantex Pharma Inc. Compositions de n-acetyle comme therapie complementaire pour le traitement et la prevention des carences en cysteine/glutathion
ITTO20030789A1 (it) 2003-10-07 2005-04-08 Professional Dietetics Srl Composizione a base di amino acidi per il trattamento
JP5473190B2 (ja) 2003-10-16 2014-04-16 ネステク ソシエテ アノニム 化学療法又は放射線療法の副作用に対する栄養組成物
US20050107338A1 (en) 2003-11-17 2005-05-19 Seidman Michael D. Nutritional supplement enhancing mitochondrial function
WO2005049006A1 (fr) 2003-11-21 2005-06-02 Ajinomoto Co., Inc. Remede contre les diabetes
EP1543735B1 (fr) 2003-12-20 2015-10-07 Nestec S.A. Composition nutritionnelle de cicatrisation des plaies
WO2005072721A1 (fr) 2004-01-28 2005-08-11 Ajinomoto Co., Inc. Composition medicinale pour prevenir ou traiter des troubles nerveux suite á une diminution locale du debit sanguin dans le cerveau
JP4568870B2 (ja) 2004-02-27 2010-10-27 独立行政法人農業・食品産業技術総合研究機構 遊離アミノ酸を富化した食品素材及びその製造法
US20090076111A1 (en) 2004-03-02 2009-03-19 Lee Steve S Methods for improving glycemic control in humans
US20050233013A1 (en) 2004-03-02 2005-10-20 Lee Steve S Methods for enhancing the transport of glucose for balancing blood sugar levels
US20050215640A1 (en) 2004-03-26 2005-09-29 Baxter Jeffrey H HMB compositions and uses thereof
JP4815752B2 (ja) 2004-04-01 2011-11-16 味の素株式会社 アミノ酸含有飲食品
WO2005110124A1 (fr) 2004-04-15 2005-11-24 Abbott Laboratories Composition et procedes pour gestion nutritionnelle de patients a maladie hepatique
CN1582912A (zh) 2004-06-10 2005-02-23 武汉启瑞科技发展有限公司 L－鸟氨酸和 l－门冬氨酸组合物
US20060002913A1 (en) 2004-06-22 2006-01-05 Gehlsen Kurt R Use of histamine and related compounds to treat disorders affecting muscle function
KR20150055100A (ko) 2004-07-14 2015-05-20 아지노모토 가부시키가이샤 Ｃ형 간염 바이러스 양성 사람 간경변 환자용 간암 발생·진전 억제제
US8501676B2 (en) 2004-07-19 2013-08-06 N.V. Nutricia Preparation for use of aspartate for regulating glucose levels in blood
EP1637163A1 (fr) 2004-09-21 2006-03-22 Andreas Kluge Indicateur pour la compliance thérapeutique
JP5177785B2 (ja) 2004-11-02 2013-04-10 味の素株式会社 周術期患者用薬剤
EP2319581B1 (fr) 2004-11-26 2015-02-25 UCL Business PLC Compostions comprenant ornithine et phenylacetate ou phenylbutyrate pour le traitement de l' encéphalopathie hépatique
WO2006083381A2 (fr) 2004-12-03 2006-08-10 University Of Maryland, Baltimore Composition de traitement de la toxicite du gaz moutarde et ses procedes d'utilisation
EP1829540A4 (fr) 2004-12-10 2008-04-02 Ajinomoto Kk Preparation prophylactique/therapeutique contre une maladie du foie
JP5604673B2 (ja) 2005-01-31 2014-10-15 隆宣 山本 中枢神経系の疲労回復又は疲労予防のための組成物
CN1679941A (zh) * 2005-02-02 2005-10-12 北京阜康仁生物制药科技有限公司 一种由牛磺酸和治疗肝病的药物组成的复方制剂及其制备方法
CA2537647A1 (fr) 2005-03-01 2006-09-01 Six Star Formulations Ltd. Composition de complement alimentaire favorisant la croissance, la recuperation et le raffermissement des muscles
EP2060914A3 (fr) 2005-03-15 2010-04-07 Nestec S.A. Compositions alimentaires pour la disponibilité biologique de modulation de vitamine C
WO2006102451A2 (fr) 2005-03-21 2006-09-28 Abbott Laboratories Composition d'acides amines pour ameliorer la tolerance au glucose
EP1865944B1 (fr) 2005-03-29 2018-08-29 Ajinomoto Co., Inc. Composition à base d'acides aminés utilisée pour prévenir ou remédier à la diminution de la masse musculaire squelettique de personnes âgées, comprenant de la L-leucine
MX2007012450A (es) 2005-04-06 2008-02-12 Novartis Ag Un metodo y composicion para mejorar nutricionalmente el control de la glucosa y la accion de la insulina.
US8993627B2 (en) 2005-04-21 2015-03-31 Sentient Lifesciences, Inc. N-acetylcysteine amide (NAC amide) for the treatment of diseases and conditions associated with oxidative stress
EP1890688A2 (fr) 2005-06-14 2008-02-27 Nestec S.A. Methode nutritionnelle
WO2006137469A1 (fr) 2005-06-22 2006-12-28 Ajinomoto Co., Inc. Activateur du récepteur métabotropique du glutamate
US20100104548A1 (en) 2005-06-24 2010-04-29 Albert Einstein College Of Medicine Of Yeshiva University Modulation of amino acid metabolism in the hypothalamus
EP1920770A4 (fr) 2005-07-01 2010-09-29 Ajinomoto Kk Agent thérapeutique contre l'affection abdominale inflammatoire et inhibiteur de la production de tnf- alpha
JP5682990B2 (ja) 2005-08-04 2015-03-11 味の素株式会社 酸化型アルブミン低下剤
JP5067160B2 (ja) 2005-08-05 2012-11-07 味の素株式会社 肝癌発生・進展抑制剤
US8148356B2 (en) 2005-08-24 2012-04-03 Cumberland Pharmaceuticals, Inc. Acetylcysteine composition and uses therefor
AU2006284088B2 (en) 2005-08-26 2011-09-29 Nestec S.A. Compositions and methods for improving functional vascular integrity, cellular survival and reducing apoptosis in ischemia or after ischemic episode in the brain
EP1774973A1 (fr) 2005-10-12 2007-04-18 Nutricia N.V. Composition riche en leucine
BRPI0617824A2 (pt) 2005-10-28 2011-08-09 Nestec Sa métodos para o uso de aminoácidos de cadeia ramificada
US20080317886A1 (en) 2005-11-03 2008-12-25 Sparkman Dennis R Compositions for Preventing and Reducing Delayed Onset Muscle Soreness
WO2007056376A2 (fr) 2005-11-07 2007-05-18 Perque, Llc. Compositions pour reguler des troubles metaboliques et procedes d'utilisation de celles-ci
PT1957061E (pt) 2005-11-30 2011-07-06 Nestec Sa Combinação compreendendo, pelo menos, um aminoácido e um inibidor de pkr para utilização no tratamento da perda muscular
RU2469719C2 (ru) 2005-12-19 2012-12-20 Абботт Лаборэтриз СПОСОБ ЛЕЧЕНИЯ АЛЛЕРГИИ, СПОСОБ ЛЕЧЕНИЯ АСТМЫ, СПОСОБ СНИЖЕНИЯ РИСКА РАЗВИТИЯ ИНФЕКЦИИ И СПОСОБ ЛЕЧЕНИЯ СОСТОЯНИЯ, ХАРАКТЕРИЗУЮЩЕГОСЯ ДИСБАЛАНСОМ СОДЕРЖАНИЯ ЦИТОКИНОВ ТИПОВ 1 И 2, ПОСРЕДСТВОМ β-ГИДРОКСИ-β-МЕТИЛБУТИРАТА
CN101365350A (zh) 2006-01-09 2009-02-11 雀巢技术公司 应激患者的治疗
EP1983849B1 (fr) 2006-01-20 2013-04-03 Innova Food AB Préparation alimentaire comprenant des acides aminés
PL1981358T3 (pl) 2006-01-31 2011-04-29 Nestec Sa Kompozycja żywieniowa dla noworodków z niską wagą urodzeniową
US20070270355A1 (en) 2006-05-11 2007-11-22 Garcia Ramon D Sport drink containing amino acids and carbohydrates
JP5100033B2 (ja) 2006-05-16 2012-12-19 大塚製薬株式会社 消化管及び腎臓の萎縮抑制剤
US20070286909A1 (en) 2006-06-07 2007-12-13 Daniel S. Smith Amino acid compositions
CN101454000A (zh) 2006-06-13 2009-06-10 明治乳业株式会社 含有氨基酸组合物的抗疲劳剂
JP2008050277A (ja) 2006-08-22 2008-03-06 Ajinomoto Co Inc 鉄欠乏性貧血症治療用組成物
US9192593B2 (en) 2006-08-30 2015-11-24 Ajinomoto Co., Inc. Amino-acid containing composition for inhibiting accumulation of fat
JP2010506883A (ja) 2006-10-19 2010-03-04 ネステク ソシエテ アノニム 癌患者に対する長期栄養供給
US20080102137A1 (en) 2006-10-31 2008-05-01 Guffey Manning V R Composition and method for etiological treatment and prevention of diseases and/or complications associated with chronic glucose metabolism destabilization
GB0624879D0 (en) 2006-12-14 2007-01-24 Shs Int Ltd Treatment of pervasive development disorders
EP1932437A1 (fr) 2006-12-15 2008-06-18 Nestec S.A. Formule infantile
CN100518815C (zh) 2007-02-15 2009-07-29 北京苏里曼医药科技有限公司 一种氨基酸组合物
US20080268038A1 (en) 2007-04-26 2008-10-30 Wolfe Robert R Compositions and Approaches for Increasing Diet Induced Thermogenesis, Inducing Weight Loss and Maintaining Muscle Mass and Strength
CN101332209B (zh) 2007-06-25 2010-12-08 三菱制药（广州）有限公司 治疗肝性脑病的复方氨基酸注射液
US8466187B2 (en) 2007-09-18 2013-06-18 Thermolife International, Llc Amino acid compositions
US7777074B2 (en) 2007-09-18 2010-08-17 Thermolife International, Llc Amino acid compounds
US8455531B2 (en) 2007-09-18 2013-06-04 Thermolife International, Llc Amino acid compositions
KR100970664B1 (ko) 2007-10-11 2010-07-15 한화제약주식회사 Ｌ-오르니틴-ｌ-아스파테이트를 함유한 겔제의 제조방법 및그 겔제
JP2011504879A (ja) 2007-11-26 2011-02-17 ネステク ソシエテ アノニム 二本鎖ｒｎａ依存性タンパク質キナーゼの活性化を阻害し腫瘍成長を阻害する組成物及び方法
CN101214050B (zh) 2007-12-28 2011-08-31 叶高山 一种具有提神、抗疲劳、醒酒功能的保健饮料
BRPI0822238B8 (pt) 2008-01-04 2021-05-25 Nestec Sa composições compreendendo ácidos graxos insaturados e compostos liberadores de óxido nítrico
US7790688B2 (en) 2008-01-11 2010-09-07 Healthspan Solutions, Llc Compositions and methods for increasing muscle mass, strength, and functional performance in the elderly
US20090186098A1 (en) 2008-01-18 2009-07-23 Jose Briceno Sports drink composition
ATE523095T1 (de) 2008-01-25 2011-09-15 Cesar Gallia S R L Aminosäurenkonzentrat in wässrigem gel und mittels verdünnung besagten konzentrats mit wasser erhaltenes getränk zur bekämpfung von müdigkeit
US8716249B2 (en) 2008-01-31 2014-05-06 Energy Light Llc Compositions and methods for improving cardiovascular health
CA2713759A1 (fr) 2008-02-05 2009-08-13 Healthspan Solutions, Llc Systemes et procedes d'utilisation d'une nutrition therapeutique pour la gestion des problemes de sante lies ou specifiques a l'age des personnes agees
WO2009099628A2 (fr) 2008-02-07 2009-08-13 Nestec S.A. Compositions et procédés influençant la récupération des effets d' une activité physique intense
EP2098124A1 (fr) 2008-03-03 2009-09-09 Nestec S.A. Gel de glucide
EP2098126A1 (fr) 2008-03-03 2009-09-09 Nestec S.A. Barre de glucide
WO2009137827A2 (fr) 2008-05-09 2009-11-12 Tiara Pharmaceuticals, Inc. Libération contrôlée de n-acétylcystéine (nac) en vue de la réduction de l'inflammation systémique et/ou vasculaire
WO2009149196A1 (fr) 2008-06-04 2009-12-10 Phenolics, Llc. Formulations à enrobage entérique de polyéthylèneglycol et d’un ou plusieurs acides aminés solubles pour ingestion orale et leur assimilation améliorée
US20100021573A1 (en) 2008-07-22 2010-01-28 Michael J Gonzalez Compositions and methods for the prevention of cardiovascular disease
ES2556765T3 (es) 2008-09-19 2016-01-20 Nestec S.A. Soporte nutricional para prevenir o moderar la parálisis de la médula ósea o la neutropenia durante el tratamiento anticáncer
EP2165713B1 (fr) 2008-09-19 2012-11-14 Nestec S.A. Lactosérum améliorant la function du thymus
EP2351562A4 (fr) 2008-10-27 2012-09-05 Ajinomoto Kk Solution solide de valine, isoleucine et leucine et sa methode de production
US8362080B2 (en) 2008-12-18 2013-01-29 Baylor College Of Medicine Increasing glutathione levels for therapy
US9314444B2 (en) 2009-01-12 2016-04-19 Biokier, Inc. Composition and method for treatment of NASH
US20120178672A1 (en) 2009-03-18 2012-07-12 Wolfe Robert R Compositions and Methods for Sparing Muscle in Renal Insufficiency and During Hemodialysis
WO2010108542A1 (fr) 2009-03-25 2010-09-30 Nestec S.A. Base de saveur de renforcement du goût naturel et procédé pour sa préparation
PT3686183T (pt) 2009-04-03 2022-10-03 Ocera Therapeutics Inc Fenilacetato de l-ornitina e métodos de preparação do mesmo
WO2010126353A1 (fr) 2009-04-27 2010-11-04 N.V. Nutricia Mélange de protéines à base de pois et utilisation de celui-ci dans une composition nutritionnelle liquide appropriée pour l'alimentation entérale
US8703719B1 (en) 2009-05-18 2014-04-22 Bio-Engineered Supplements And Nutrition, Inc. Method and composition for improved muscle performance
JP5749255B2 (ja) 2009-06-08 2015-07-15 ユーシーエル ビジネス ピーエルシー Ｌ−オルニチンフェニル酢酸塩を用いる門脈圧亢進の治療及び肝機能の修復
WO2010143939A1 (fr) 2009-06-09 2010-12-16 N.V. Nutricia Nutrition destinée à améliorer la résistance musculaire des personnes âgées
IN2012DN00486A (fr) 2009-07-20 2015-05-22 Nestec Sa
WO2011030104A1 (fr) 2009-09-09 2011-03-17 Rajiv Jalan Acétate de phényle et/ou butyrate de phényle (non-ornithine) pour abaisser la pression sanguine dans la veine porte
CN101664384B (zh) 2009-09-18 2011-09-14 杭州市第六人民医院 N-乙酰半胱氨酸盐木糖醇注射液及其制备方法和应用
WO2011044230A2 (fr) 2009-10-06 2011-04-14 Goldstein Glenn A N-acétylcystéine amide (nac amide) destiné au traitement de maladies et de conditions
WO2011043647A1 (fr) 2009-10-09 2011-04-14 N.V. Nutricia Composition d'acide aminé avec aptitude à la dispersion améliorée
EP2327316B1 (fr) 2009-11-29 2016-11-16 Premier Nutrition Corporation Procédé d'amélioration de la synthèse de protéines musculaires
EP2327315B1 (fr) 2009-11-29 2013-10-09 Nestec S.A. Protocoles de dosage pour augmenter la synthèse des protéines chez un individu actif
JP2011132174A (ja) 2009-12-24 2011-07-07 Kirin Holdings Co Ltd 持久力向上剤
WO2011078654A1 (fr) 2009-12-24 2011-06-30 N.V. Nutricia Composition nutritionnelle hypocalorique riche en protéines destinée à la stimulation de la synthèse des protéines musculaires
WO2011097273A1 (fr) 2010-02-02 2011-08-11 Martek Biosciences Corporation Méthodes et compositions permettant le traitement de la stéatose hépatique non alcoolique au moyen d'acide docosahexaénoïque et de n-acétyl-l-cystéine
EP2544555B1 (fr) 2010-03-12 2018-05-16 Nestec S.A. Compositions destinées à masquer la saveur de leucine et leurs procédés de fabrication
WO2011119023A1 (fr) 2010-03-26 2011-09-29 N.V. Nutricia Formule pour nourrisson à faible teneur en protéine dotée d'acides aminés essentiels accrus
US20130210715A1 (en) 2010-04-26 2013-08-15 Nestec S.A. Nutritional compositions and methods for weaning from parenteral nutrition to enteral nutrition
US8840950B2 (en) 2010-05-26 2014-09-23 Jacqueline M. Hibbert Compositions of nutrition supplementation for nutritional deficiencies and method of use therefore
WO2012005568A1 (fr) 2010-07-07 2012-01-12 N.V. Nutricia Composition nutritive de stimulation de synthèse de protéines musculaires
KR101213825B1 (ko) 2010-07-16 2012-12-18 서울대학교산학협력단 세린을 유효성분으로 함유하는 지방간 질환의 예방 및 치료용 조성물
CN103038356A (zh) 2010-07-21 2013-04-10 坎伯兰医药品股份有限公司 乙酰半胱氨酸组合物及其使用方法
US20120020947A1 (en) 2010-07-22 2012-01-26 Northern Innovations And Formulations Corp. Compositions and methods for increasing lean muscle mass after exercise
CN101912394B (zh) * 2010-08-06 2013-11-06 岳茂兴 一种用于治疗凝血障碍出血的药物组合物及其用途
MX360062B (es) 2010-10-06 2018-10-22 Ocera Therapeutics Inc Metodos de elaboracion de fenilacetato de l-ornitina.
EP2444083A1 (fr) 2010-10-21 2012-04-25 Nestec S.A. Cystéine et ingestion d'aliments
CA2821725A1 (fr) 2010-12-22 2012-06-28 Abbott Laboratories Produits nutritionnels comprenant du beta-hydroxy-beta-methylbutyrate de calcium et de l'acide linoleique conjugue
BR112013016351A2 (pt) 2010-12-27 2018-06-26 Abbott Lab Métodos para facilitar recuperação muscular após um período de desuso empregando o beta- hidróxi-beta-metilbutirato
WO2012097061A1 (fr) 2011-01-13 2012-07-19 Abbott Laboratories Compositions nutritionnelles et procédés pour améliorer le métabolisme protéique des muscles squelettiques
ES2828479T3 (es) 2011-01-25 2021-05-26 Nestle Sa Métodos y composiciones para tratar, reducir o prevenir el deterioro del sistema visual de los animales
RU2491062C2 (ru) 2011-03-16 2013-08-27 Общество С Ограниченной Ответственностью "Биотехнологии Пущино" Композиции протекторов острых и хронических печеночных энцелопатий и способ лечения острых и хронических печеночных энцелопатий
WO2012128982A2 (fr) 2011-03-18 2012-09-27 Nestec S.A. Compositions et procédés utiles pour améliorer des maladies liées à l'âge
CN102327259A (zh) 2011-03-31 2012-01-25 姜国辉 具有显著化学性肝损伤保护功能的复合生物制剂
WO2012135499A1 (fr) 2011-03-31 2012-10-04 Ganeden Biotech, Inc. Compositions nutritionnelles probiotiques pour l'activité sportive
AU2012241895A1 (en) 2011-04-12 2013-10-03 Nestec S.A. Nutritional compositions including branched chain fatty acids for wound healing
CA2831001A1 (fr) 2011-04-18 2012-10-26 Nestec S.A. Compositions nutritionnelles comprenant de l'alpha-hydroxyisocaproique
US20120270860A1 (en) 2011-04-19 2012-10-25 Gihyun Yoon Methods for treating or preventing alcohol-related disorders or craving-related disorders
WO2012145346A2 (fr) 2011-04-21 2012-10-26 Nestec S.A. Compositions nutritionnelles pour améliorer de la performance et procédés pour les préparer et les utiliser
US8828426B2 (en) 2011-06-07 2014-09-09 Zx Pharma, Llc Multiparticulate L-carnitine compositions and related methods
US20130090356A1 (en) 2011-06-24 2013-04-11 Jon D. Kaiser Compositions and methods for treatment of neuropsychological deficits
US20140135396A1 (en) 2011-07-05 2014-05-15 Beth Israel Deaconess Medical Center, Inc. Treatment of Acetaminophen-Induced Liver Damage by the Administration of Modulators of Nitric Oxide
EP2742938B1 (fr) 2011-08-08 2018-05-09 Ajinomoto Co., Inc. Composition à teneur en acides aminés pour augmenter la récupération de la fatigue musculaire
AU2012299126B2 (en) 2011-08-19 2016-05-26 Musclepharm Corporation Compositions and methods for use in promoting lean body mass
EP2574333B1 (fr) 2011-09-27 2017-01-11 Friulchem SpA Comprimé effervescent de N-acétylcystéine et ses applications thérapeutiques
EP2580967A1 (fr) 2011-10-11 2013-04-17 Nestec S.A. Accélération de récupération musculaire après une atrophie du muscle induite par l'immobilisation
EP2583565A1 (fr) 2011-10-21 2013-04-24 Nestec S.A. Utilisation de micelles de protéines de lactosérum pour améliorer la dépense énergétique et la satiété
EP2583563A1 (fr) 2011-10-21 2013-04-24 Nestec S.A. Micelles de protéine de lactosérum contre l'amyotrophie et la sarcopénie
WO2013075095A1 (fr) 2011-11-18 2013-05-23 The Board Of Trustees Of The University Of Arkansas Utilisation d'un apport complémentaire en acides aminés en vue d'une récupération musculaire améliorée
WO2013077893A1 (fr) 2011-11-21 2013-05-30 Emmaus Medical, Inc. Procédés et compositions pour le traitement du diabète et de symptômes associés
JP5788527B2 (ja) 2011-12-02 2015-09-30 味の素株式会社 キナーゼ阻害剤の副作用低減剤
US20150004202A1 (en) 2012-01-19 2015-01-01 Shoichi Shirotake Antibacterial agent against plant disease-causing bacteria
US9198454B2 (en) 2012-03-08 2015-12-01 Nusirt Sciences, Inc. Compositions, methods, and kits for regulating energy metabolism
WO2013188258A1 (fr) 2012-06-11 2013-12-19 Abbott Laboratories Utilisation de hmb pour améliorer les résultats en matière de santé pour patients hospitalisés
ES2609654T3 (es) 2012-07-31 2017-04-21 Nestec S.A. Composición nutritiva para promover la salud del aparato locomotor de pacientes que sufren la enfermedad del intestino inflamatorio (IBD)
CA2884717A1 (fr) 2012-09-14 2014-03-20 Nestec S.A. Nouvelles compositions aromatiques a arome et/ou duree de conservation d'arome ameliores
US8747921B2 (en) 2012-09-19 2014-06-10 Quality Ip Holdings, Inc. Methods for improving health in humans
US9198889B2 (en) 2012-09-19 2015-12-01 Quality IP Holdings, LLC Methods for treating post-traumatic stress disorder
US9066953B2 (en) 2012-09-20 2015-06-30 Quality IP Holdings, LLC Methods for increasing endurance and fat metabolism in humans
CN102961377A (zh) 2012-11-08 2013-03-13 湖北一半天制药有限公司 复方氨基酸注射液（20aa）的制备方法
ES2633769T3 (es) 2012-12-04 2017-09-25 Nestec S.A. Hexanoilglicina como biomarcador para la predisposición al aumento de peso y a la obesidad
RU2664479C2 (ru) 2013-02-04 2018-08-17 Серес Терапеутикс, Инк. Композиции и способы
EP3427730B1 (fr) 2013-03-11 2024-07-10 University of Florida Research Foundation, Inc. Materiaux et méthodes pour l'amelioration de la fonction pulmonale
AU2014236687A1 (en) 2013-03-15 2015-09-10 Nusirt Sciences, Inc. Leucine and nicotinic acid reduces lipid levels
AU2014242565A1 (en) 2013-03-26 2015-10-15 Premier Nutrition Corporation Methods for enhancing muscle protein synthesis following concurrent training
CN105120689A (zh) 2013-04-15 2015-12-02 雀巢产品技术援助有限公司 乳清蛋白质与电肌肉刺激组合的用途
ES2844199T3 (es) 2013-04-16 2021-07-21 Childrens Hospital Philadelphia Composiciones y métodos para el tratamiento de lesiones cerebrales
US20140357576A1 (en) 2013-05-31 2014-12-04 Nestec S.A. Methods for enhancement of muscle protein synthesis
AU2014302893B2 (en) 2013-06-28 2017-07-13 Société des Produits Nestlé S.A. Compositions and methods for enhancing exercise performance
EP3027181A1 (fr) 2013-07-31 2016-06-08 Leeds Beckett University Complément alimentaire
WO2015048348A2 (fr) 2013-09-25 2015-04-02 Pronutria, Inc. Compositions et formulations pour augmenter la fonction rénale et traitement et prévention de maladies rénales, et procédés de production et d'utilisation de celles-ci
US20180125926A1 (en) 2013-09-25 2018-05-10 Axcella Health Inc. Compositions and Formulations and Methods of Production and Use Thereof
BR112016007487A2 (pt) 2013-10-09 2017-08-01 Nestec Sa composições compreendendo citrulina e leucina e seu uso no tratamento de diabetes e de síndrome meta-bólica
JP2017501113A (ja) 2013-10-23 2017-01-12 ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ アミノ酸によるｍＴＯＲＣ１の調節およびその使用
KR20160119863A (ko) 2014-02-27 2016-10-14 뉴서트 사이언시스, 인크. 간 지방증의 감소 또는 예방을 위한 조성물 및 방법
GB2523578A (en) 2014-02-28 2015-09-02 Daniel Nelson A nutritional supplement
WO2015161448A1 (fr) 2014-04-22 2015-10-29 Wuhan Ll Science And Technology Development Co., Ltd. Compositions contenant de l'ornithine ou de l'aspartate et leurs utilisations
CN105092753B (zh) 2014-05-20 2016-09-07 中国科学院大连化学物理研究所 组合型胺类代谢标志物的应用及试剂盒
WO2016003263A1 (fr) 2014-07-01 2016-01-07 N.V. Nutricia Régime alimentaire à base d'acides aminés avec un goût amélioré
US10217645B2 (en) 2014-07-25 2019-02-26 Versum Materials Us, Llc Chemical mechanical polishing (CMP) of cobalt-containing substrate
CN105360846A (zh) * 2014-08-19 2016-03-02 武汉宏博生物技术有限公司 一种氨基酸饮料
US20160158305A1 (en) 2014-09-19 2016-06-09 Chip E. Thomson Additives and supplements
ES2960218T3 (es) 2014-10-14 2024-03-01 Nestle Sa Mejora en la funcionalidad del músculo de hombres ancianos
MX2017006685A (es) 2014-11-24 2018-01-15 Ucl Business Plc Tratamiento de enfermedades asociadas con activacion de celulas estrelladas hepaticas usando terapias reductoras de amoniaco.
ES2777775T3 (es) 2014-12-04 2020-08-06 Professional Dietetics Int Srl In Forma Abbreviata Pd Int Srl Composicion a base de aminoacidos para recuperacion de fibroelastina en tejidos conectivos dermicos
WO2016094316A1 (fr) 2014-12-08 2016-06-16 Synaptamine, Inc. Composés anti-rds et procédé de fabrication et d'administration de ceux-ci pour induire l'homéostasie de la dopamine
EP3034074A1 (fr) 2014-12-18 2016-06-22 Universitat De València, Estudi General Composé pour le traitement de la dystrophie myotonique de type 1
EP3247345A1 (fr) 2015-01-23 2017-11-29 Nestec S.A. Traitement ou prévention de l'inflammation à l'aide de sérine
WO2016116580A1 (fr) 2015-01-23 2016-07-28 Nestec S.A. Composition nutritionnelle utile dans le traitement de patients atteints d'une ibd
WO2016116585A1 (fr) 2015-01-23 2016-07-28 Nestec S.A. Promotion de la cicatrisation de la muqueuse intestinale à l'aide de la proline, de la sérine et de la thréonine
CN107209173B (zh) 2015-01-23 2020-02-07 雀巢产品有限公司 用于确定患者的独特的营养需求的方法
JP6847668B2 (ja) 2015-01-27 2021-03-24 昇一 城武 ナノ粒子を有効成分とする皮膚炎の治療又は予防剤
US20180036270A1 (en) 2015-02-13 2018-02-08 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College A method of protecting against carbonyl stress induced ischemia-reperfusion injury in the diabetic brain via administration of n-acetylcysteine
AU2016217818A1 (en) 2015-02-13 2017-07-13 Société des Produits Nestlé S.A. Treatment or prevention of surgery-induced cachexia and/or expression of myeloid-derived suppressor cells and pro-inflammatory cytokines
FR3032883B1 (fr) 2015-02-24 2017-03-17 International Nutrition Res Company Composition pour la prevention et le traitement de la steatose et de la steatohepatite metaboliques
US20160302451A1 (en) 2015-04-16 2016-10-20 Michael Hudnall Medical Food for Patients with Chronic Liver Disease
JP2018513171A (ja) 2015-04-20 2018-05-24 オセラ セラピューティクス， インコーポレイテッド Ｌ−オルニチンフェニルアセテート製剤
US10123985B2 (en) 2015-06-08 2018-11-13 Whitehead Institute For Biomedical Research Therapeutic strategies for treating mitochondrial disorders
EP3310349B1 (fr) 2015-06-22 2021-01-13 Société des Produits Nestlé S.A. Compositions et méthodes pour augmenter la neurogénèse chez l'animal
WO2017001590A1 (fr) 2015-06-30 2017-01-05 Nestec S.A. Composition appropriée pour protéger des micro-organismes
WO2017011471A1 (fr) 2015-07-15 2017-01-19 Unigen, Inc. Compositions, méthodes, et compositions à usage médical destinées à traiter le foie et à le maintenir en bonne santé
ES2875601T3 (es) 2015-08-14 2021-11-10 Nestle Sa Composiciones alimentarias semihúmedas que mantienen una textura blanda
WO2017031131A1 (fr) 2015-08-18 2017-02-23 Ocera Therapeutics, Inc. Traitement et prévention de la perte musculaire au moyen de l-ornithine en combinaison avec au moins un parmi l'acétate de phényle et le butyrate de phényle
WO2017033272A1 (fr) 2015-08-25 2017-03-02 昇一 城武 Agent antimicrobien luttant contre les germes ayant un excellent effet de lutte contre les maladies des plantes
US20170079897A1 (en) 2015-09-20 2017-03-23 Matthew Brissette MINUS Composition for hair application and methods of hair care
AU2016325556B2 (en) 2015-09-25 2023-02-16 Ocera Therapeutics, Inc. Treatment and prevention of neuronal cell loss using L-ornithine in combination with at least one of phenylacetate and phenylbutyrate
US20170196944A1 (en) 2015-09-28 2017-07-13 Robert Portman Method to reduce muscle atrophy following orthopedic surgery
US11219611B2 (en) 2015-11-13 2022-01-11 Ocera Therapeutics, Inc. Formulations of L-ornithine phenylacetate
AU2016353350B2 (en) 2015-11-13 2021-09-23 Ocera Therapeutics, Inc. Formulation of L-ornithine phenylacetate
CN108348553A (zh) 2015-11-20 2018-07-31 雀巢产品技术援助有限公司 使用乳清蛋白以改善或维持肌肉质量的方法
GB2561747B (en) 2015-12-21 2021-05-12 Nanjing Jianrong Bio Tech Co Ltd Composition for treating motor neuron diseases and use thereof
JP2019501182A (ja) 2016-01-08 2019-01-17 コロナリーコンセプツ エルエルシー 肝性脳症の処置のための治療剤の食品ベースの送達
GB201600990D0 (en) 2016-01-19 2016-03-02 Abbott Lab Pharmaceutical or nutritional combination
US20190133147A1 (en) 2016-05-11 2019-05-09 Tsubo Solutions Pty Ltd Confectionery product
BR112018072451A2 (pt) 2016-05-27 2019-02-19 Nestec S.A. composição nutricional para tratamento ou prevenção de mobilidade prejudicada
PL238958B1 (pl) 2016-06-29 2021-10-25 Olimp Laboratories Spolka Z Ograniczona Odpowiedzialnoscia Kompozycja aminokwasowa do stosowania przed wysiłkiem fizycznym
US20180015122A1 (en) 2016-07-14 2018-01-18 Companion Supplements, LLC Pharmaceutical composition effective in preventing adverse effects associated with the use of glucocorticoids
US11033522B2 (en) 2016-08-09 2021-06-15 David C Scott Free amino acid preparation and uses thereof
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
JOP20190147A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض واضطرابات العضلات
CN106632605B (zh) 2016-12-22 2020-06-16 浙江海洋大学 利用金枪鱼下脚料制备的具有肝损伤修复作用的活性肽
SE540582C2 (en) 2016-12-22 2018-10-02 Scandibio Therapeutics Ab Substances for treatment of fatty liver-related conditions
US11020354B2 (en) 2017-01-19 2021-06-01 Otologic Pharmaceuticals, Inc. Formulations of n-acetylcysteine and uses thereof
US11617731B2 (en) 2017-04-28 2023-04-04 Axcella Health, Inc. Amino acid compositions and their use for the treatment of traumatic brain injury
CN107242552A (zh) 2017-07-07 2017-10-13 上海东锦食品集团有限公司 具有缓解体力疲劳及增强免疫力功能的保健食品组合物
JOP20200033A1 (ar) 2017-08-14 2020-02-13 Axcella Health Inc تركيبات حمض أميني لمعالجة مرض كبدي
KR20200040276A (ko) 2017-08-14 2020-04-17 악셀라 헬스 인크. 신경 손상 치료를 위한 아미노산 조성물
CN108041501A (zh) 2017-12-22 2018-05-18 北京康比特体育科技股份有限公司 一种促进疲劳恢复的蛋白组合物及其制备方法
EP3810123A1 (fr) 2018-06-20 2021-04-28 Axcella Health Inc. Compositions et procédés pour le traitement de l'infiltration de graisse dans le muscle
WO2019246201A1 (fr) 2018-06-20 2019-12-26 Axcella Health Inc. Procédés de fabrication de compositions d'acides aminés
CU20200106A7 (es) 2018-06-20 2021-08-06 Axcella Health Inc Composiciones y métodos para el tratamiento de hemoglobinopatías y talasemias
WO2019246221A1 (fr) 2018-06-20 2019-12-26 Axcella Health Inc. Compositions et procédés pour le traitement de maladies et troubles hépatiques
WO2019246256A1 (fr) 2018-06-20 2019-12-26 Axcella Health Inc. Compositions pour thérapie et soin contenant des acides aminés ayant un goût amer
CN108524453A (zh) 2018-07-05 2018-09-14 扬子江药业集团广州海瑞药业有限公司 一种门冬氨酸鸟氨酸的药物组合物

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