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MA22646A1 - Diastereoisomeres du 3-cepheme-4-carboxylate de 1-(isopropoxycarbonyloxy) ethyle, procede pour leur preparation et compositions les contenant . - Google Patents

Diastereoisomeres du 3-cepheme-4-carboxylate de 1-(isopropoxycarbonyloxy) ethyle, procede pour leur preparation et compositions les contenant .

Info

Publication number
MA22646A1
MA22646A1 MA22936A MA22936A MA22646A1 MA 22646 A1 MA22646 A1 MA 22646A1 MA 22936 A MA22936 A MA 22936A MA 22936 A MA22936 A MA 22936A MA 22646 A1 MA22646 A1 MA 22646A1
Authority
MA
Morocco
Prior art keywords
formula
general formula
solution
acid
isopropoxycarbonyloxy
Prior art date
Application number
MA22936A
Other languages
English (en)
Inventor
Fischer G
Krass N
Isert D
Horlein R
Gerlach U
Lattrell R
Defoba E
Wollmann T
Stache U
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of MA22646A1 publication Critical patent/MA22646A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
MA22936A 1991-09-07 1992-09-07 Diastereoisomeres du 3-cepheme-4-carboxylate de 1-(isopropoxycarbonyloxy) ethyle, procede pour leur preparation et compositions les contenant . MA22646A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4129771 1991-09-07

Publications (1)

Publication Number Publication Date
MA22646A1 true MA22646A1 (fr) 1993-04-01

Family

ID=6440090

Family Applications (1)

Application Number Title Priority Date Filing Date
MA22936A MA22646A1 (fr) 1991-09-07 1992-09-07 Diastereoisomeres du 3-cepheme-4-carboxylate de 1-(isopropoxycarbonyloxy) ethyle, procede pour leur preparation et compositions les contenant .

Country Status (30)

Country Link
US (3) US5461043A (fr)
EP (1) EP0531875B1 (fr)
JP (1) JP2667943B2 (fr)
KR (1) KR100239253B1 (fr)
CN (1) CN1040002C (fr)
AT (1) ATE262533T1 (fr)
AU (1) AU647307B2 (fr)
BR (1) BR9203464A (fr)
CA (1) CA2077562C (fr)
CZ (1) CZ282320B6 (fr)
DE (1) DE59209994D1 (fr)
DK (1) DK0531875T3 (fr)
EG (1) EG20237A (fr)
ES (1) ES2215161T3 (fr)
FI (1) FI108725B (fr)
HR (1) HRP920310A2 (fr)
HU (1) HU219588B (fr)
IL (1) IL103064A (fr)
MA (1) MA22646A1 (fr)
MX (1) MX9205081A (fr)
NO (1) NO302122B1 (fr)
NZ (1) NZ244224A (fr)
PH (1) PH30743A (fr)
PL (1) PL171644B1 (fr)
PT (1) PT531875E (fr)
RS (1) RS49877B (fr)
RU (1) RU2075480C1 (fr)
SI (1) SI9200204B (fr)
SK (1) SK279013B6 (fr)
ZA (1) ZA926710B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99898A (en) * 1990-11-09 1996-10-31 Eisai Co Ltd 7-Noble-3- Compounds Transformed Carbamoylloxy
ATE262533T1 (de) * 1991-09-07 2004-04-15 Aventis Pharma Gmbh Diastereomer des 3-cephem-4-carbonsäure-1-(- isopropoxycarbonyloxy)ethylesters und verfahren zu dessen herstellung
TW212181B (fr) * 1992-02-14 1993-09-01 Hoechst Ag
ATE164378T1 (de) * 1992-05-21 1998-04-15 Hoechst Ag Verfahren zur spaltung von cephalosporin prodrugestern zu 7-amino-3-methoxymethylceph-3-em-4-carbonsäure
US5817351A (en) * 1995-04-07 1998-10-06 Abbott Laboratories Calcium fortified low pH beverage
US5928691A (en) * 1997-05-01 1999-07-27 Nestec S.A. Calcium complex and a process of making a food fortified with calcium
US6024994A (en) * 1997-11-06 2000-02-15 Nestec S.A. Calcium complexes for fortification of foods and process of making
AT413383B (de) * 1998-01-09 2006-02-15 Sandoz Ag Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil
US6036985A (en) * 1998-04-03 2000-03-14 Nestec S.A. Calcium complex and food fortified therewith
US6039986A (en) * 1998-07-10 2000-03-21 Nestec S.A. Fortification of foodstuff
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
AU7224300A (en) * 1999-05-07 2000-11-21 Ranbaxy Laboratories Limited Process for the preparation of cefpodoxime acid
IN191496B (fr) * 1999-07-30 2003-12-06 Ranbaxy Lab Ltd
US6740344B2 (en) * 2000-12-01 2004-05-25 General Mill, Inc. Calcium fortified products and methods of preparation
US7045618B2 (en) * 2001-02-27 2006-05-16 Ranbaxy Laboratories Limited Cefpodixime proxetil
EP1590353B1 (fr) * 2002-12-20 2007-10-10 Lupin Limited Procede pour preparer du cefpodoxime proxetil
EP2520578A1 (fr) 2011-05-06 2012-11-07 Lupin Limited Procédé pour la purfication de céphalosporines

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4203899A (en) * 1974-12-19 1980-05-20 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
JPS5760345B2 (fr) * 1974-12-19 1982-12-18 Takeda Chemical Industries Ltd
US4298606A (en) * 1974-12-19 1981-11-03 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
US4668783A (en) * 1974-12-19 1987-05-26 Takeda Chemical Industries, Ltd. Thiazolylacetamido cephalosporin compounds
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
FR2476087A1 (fr) * 1980-02-18 1981-08-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4486425A (en) * 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
JPS5759894A (en) * 1980-09-30 1982-04-10 Sankyo Co Ltd Cephalosporin for oral administration
JPS5896091A (ja) * 1981-12-01 1983-06-07 Sankyo Co Ltd ３−アルコキシメチルセフアロスポリン類の製造法
US4688783A (en) * 1983-04-20 1987-08-25 Dubois R Clark Bottom feed sheet feeding apparatus
JPS604189A (ja) * 1983-06-20 1985-01-10 Sankyo Co Ltd β−ラクタム系化合物の製造法
JPS604190A (ja) * 1983-06-21 1985-01-10 Sankyo Co Ltd セフアロスポリン誘導体の製法
JPS60260584A (ja) * 1985-05-14 1985-12-23 Sankyo Co Ltd セフアロスポリン誘導体
DE3804841A1 (de) * 1988-02-17 1989-08-31 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
DE3901405A1 (de) * 1989-01-19 1990-07-26 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
DE3910093A1 (de) * 1989-03-29 1990-10-04 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
US5063224A (en) * 1990-07-09 1991-11-05 Eli Lilly And Company R-cefuroxime axetil
ATE262533T1 (de) * 1991-09-07 2004-04-15 Aventis Pharma Gmbh Diastereomer des 3-cephem-4-carbonsäure-1-(- isopropoxycarbonyloxy)ethylesters und verfahren zu dessen herstellung

Also Published As

Publication number Publication date
ES2215161T3 (es) 2004-10-01
FI923966A (fi) 1993-03-08
DK0531875T3 (da) 2004-06-21
MX9205081A (es) 1993-03-01
CZ282320B6 (cs) 1997-06-11
SK276192A3 (en) 1998-05-06
KR930006031A (ko) 1993-04-20
DE59209994D1 (de) 2004-04-29
ZA926710B (en) 1993-04-28
CN1040002C (zh) 1998-09-30
EP0531875B1 (fr) 2004-03-24
RS49877B (sr) 2008-08-07
PL171644B1 (en) 1997-05-30
PT531875E (pt) 2004-08-31
HRP920310A2 (en) 1994-08-31
CN1070405A (zh) 1993-03-31
JP2667943B2 (ja) 1997-10-27
FI108725B (fi) 2002-03-15
PH30743A (en) 1997-10-17
CA2077562C (fr) 2003-07-15
US5550232A (en) 1996-08-27
IL103064A0 (en) 1993-02-21
HU219588B (hu) 2001-05-28
HU9202861D0 (en) 1992-11-30
JPH05213969A (ja) 1993-08-24
US5461043A (en) 1995-10-24
AU647307B2 (en) 1994-03-17
NO302122B1 (no) 1998-01-26
KR100239253B1 (ko) 2000-03-02
SI9200204B (en) 2001-12-31
FI923966A0 (fi) 1992-09-04
SI9200204A (en) 1993-03-31
EP0531875A3 (en) 1993-03-24
CZ276192A3 (en) 1993-08-11
NO923452D0 (no) 1992-09-04
EP0531875A2 (fr) 1993-03-17
AU2218392A (en) 1993-03-11
RU2075480C1 (ru) 1997-03-20
YU81392A (sr) 1996-01-09
PL295834A1 (en) 1993-03-22
NZ244224A (en) 1995-04-27
US5614623A (en) 1997-03-25
CA2077562A1 (fr) 1993-03-08
HRP920310B1 (fr) 2004-12-31
HUT64544A (en) 1994-01-28
IL103064A (en) 1996-12-05
NO923452L (no) 1993-03-08
ATE262533T1 (de) 2004-04-15
EG20237A (en) 1998-05-31
BR9203464A (pt) 1993-04-13
SK279013B6 (sk) 1998-05-06

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