About: CS-27349

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

CS-27349, or L-2-α-tropinyl benzilate, is an experimental incapacitating agent. It acts as an antagonist to muscarinic acetylcholine receptors, causing delirium. It has 37% of the potency of the related compound 3-quinuclidinyl benzilate (BZ) in producing peripheral effects, but 85% of the potency in producing central effects. The mean dose required to incapacitate subjects was 1.2 times that of BZ. It has not been in use since the 1970s, and there have been no publications about its effects or long-term toxicology since then.

Property	Value
dbo:abstract	CS-27349, or L-2-α-tropinyl benzilate, is an experimental incapacitating agent. It acts as an antagonist to muscarinic acetylcholine receptors, causing delirium. It has 37% of the potency of the related compound 3-quinuclidinyl benzilate (BZ) in producing peripheral effects, but 85% of the potency in producing central effects. The mean dose required to incapacitate subjects was 1.2 times that of BZ. It has not been in use since the 1970s, and there have been no publications about its effects or long-term toxicology since then. (en)
dbo:casNumber	64471-12-1 64520-33-8
dbo:chEMBL	298138
dbo:pubchem	3049185
dbo:thumbnail	wiki-commons:Special:FilePath/CS-27349.svg?width=300
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dbo:wikiPageWikiLink	dbr:Delirium dbr:Receptor_antagonist dbr:Muscarinic_acetylcholine_receptor dbc:Benzilate_esters dbc:Chemical_weapons_of_the_United_States dbc:Deliriants dbc:Incapacitating_agents dbc:Muscarinic_antagonists dbr:Hydrochloride dbr:3-quinuclidinyl_benzilate dbr:Incapacitating_agent
dbp:c	22 (xsd:integer)
dbp:casNumber	64471 (xsd:integer) 64520 (xsd:integer)
dbp:chembl	298138 (xsd:integer)
dbp:chemspiderid	143123 (xsd:integer) 57264798 (xsd:integer)
dbp:drugName	CS-27349 (en)
dbp:dtxsid	DTXSID90983151 (en)
dbp:h	25 (xsd:integer)
dbp:index2Label	dbr:Hydrochloride
dbp:iupacName	-8 (xsd:integer)
dbp:n	1 (xsd:integer)
dbp:o	3 (xsd:integer)
dbp:pubchem	3049184 (xsd:integer) 3049185 (xsd:integer)
dbp:smiles	CN1C2CC[C@H]OCCO (en) CN1C2CC[C@H]OCCO.Cl (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	LSJGAYNIIMEDLR-SOAGJPPSSA-N (en)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Hallucinogens dbt:Reflist dbt:Short_description dbt:Cascite dbt:Muscarinic_acetylcholine_receptor_modulators dbt:Chemical_warfare
dct:subject	dbc:Benzilate_esters dbc:Chemical_weapons_of_the_United_States dbc:Deliriants dbc:Incapacitating_agents dbc:Muscarinic_antagonists
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug
rdfs:comment	CS-27349, or L-2-α-tropinyl benzilate, is an experimental incapacitating agent. It acts as an antagonist to muscarinic acetylcholine receptors, causing delirium. It has 37% of the potency of the related compound 3-quinuclidinyl benzilate (BZ) in producing peripheral effects, but 85% of the potency in producing central effects. The mean dose required to incapacitate subjects was 1.2 times that of BZ. It has not been in use since the 1970s, and there have been no publications about its effects or long-term toxicology since then. (en)
rdfs:label	CS-27349 (en)
owl:sameAs	wikidata:CS-27349 https://global.dbpedia.org/id/FdgBt
prov:wasDerivedFrom	wikipedia-en:CS-27349?oldid=1091167605&ns=0
foaf:depiction	wiki-commons:Special:FilePath/CS-27349.svg
foaf:isPrimaryTopicOf	wikipedia-en:CS-27349
foaf:name	CS-27349 (en)
is dbo:wikiPageWikiLink of	dbr:3-Quinuclidinyl_thiochromane-4-carboxylate
is foaf:primaryTopic of	wikipedia-en:CS-27349