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ZA9811081B - (Benzodioxan, Benzofuran or Benzopyran) Derivatives having fundic relaxation properties. - Google Patents

(Benzodioxan, Benzofuran or Benzopyran) Derivatives having fundic relaxation properties.

Info

Publication number
ZA9811081B
ZA9811081B ZA9811081A ZA9811081A ZA9811081B ZA 9811081 B ZA9811081 B ZA 9811081B ZA 9811081 A ZA9811081 A ZA 9811081A ZA 9811081 A ZA9811081 A ZA 9811081A ZA 9811081 B ZA9811081 B ZA 9811081B
Authority
ZA
South Africa
Prior art keywords
benzodioxan
benzopyran
benzofuran
derivatives
relaxation properties
Prior art date
Application number
ZA9811081A
Other languages
English (en)
Inventor
Piet Tom Bert Paul Wigerinck
Wim Gaston Verschueren
Marc Francis Josephin Schroven
Bruyn Marcel Frans Leopold De
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA9811081B publication Critical patent/ZA9811081B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA9811081A 1997-12-05 1998-12-03 (Benzodioxan, Benzofuran or Benzopyran) Derivatives having fundic relaxation properties. ZA9811081B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97203808 1997-12-05

Publications (1)

Publication Number Publication Date
ZA9811081B true ZA9811081B (en) 2000-06-22

Family

ID=8229014

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9811081A ZA9811081B (en) 1997-12-05 1998-12-03 (Benzodioxan, Benzofuran or Benzopyran) Derivatives having fundic relaxation properties.

Country Status (32)

Country Link
US (4) US6133277A (xx)
EP (1) EP1036073B8 (xx)
JP (1) JP2001525407A (xx)
KR (1) KR100591605B1 (xx)
CN (1) CN1155597C (xx)
AR (1) AR017195A1 (xx)
AT (1) ATE334125T1 (xx)
AU (1) AU748669B2 (xx)
BG (1) BG64624B1 (xx)
BR (1) BR9814256A (xx)
CA (1) CA2311669C (xx)
CO (1) CO5011114A1 (xx)
CZ (1) CZ297895B6 (xx)
DE (1) DE69835372T2 (xx)
EA (1) EA003365B1 (xx)
EE (1) EE04438B1 (xx)
ES (1) ES2270541T3 (xx)
HK (1) HK1028400A1 (xx)
HR (1) HRP20000340B1 (xx)
HU (1) HU224813B1 (xx)
ID (1) ID24616A (xx)
IL (1) IL136529A (xx)
MY (1) MY124586A (xx)
NO (1) NO320727B1 (xx)
NZ (1) NZ503603A (xx)
PL (1) PL191144B1 (xx)
SK (1) SK286268B6 (xx)
TR (1) TR200001542T2 (xx)
TW (1) TW577886B (xx)
UA (1) UA70308C2 (xx)
WO (1) WO1999029687A1 (xx)
ZA (1) ZA9811081B (xx)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
MXPA01012330A (es) * 1999-06-02 2002-07-30 Janssen Pharmaceutica Nv Derivados (benzodioxano, benzofurano o benzopirano) aminoalquil sustituidos.
BR0011247A (pt) 1999-06-02 2002-03-05 Janssen Pharmaceutica Nv Derivados (benzodioxano, benzofurano ou benzopirano) de pirrolidinila, piperidinila ou homopiperidinila substituìdos
JO2352B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) * 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
US6688079B2 (en) 2001-04-18 2004-02-10 Kraft Foods Holdings, Inc. Method for manufacturing flexible packages having slide closures
JPWO2003040382A1 (ja) * 2001-11-09 2005-03-03 株式会社カネカ 光学活性クロマン誘導体の製造法および中間体
ES2199086B1 (es) 2002-07-31 2005-06-01 Cepa Schwarz Pharma Sl Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
US7071821B2 (en) * 2003-05-14 2006-07-04 Bellsouth Intellectual Property Corporation Method and system for alerting a person to a situation
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
CA2580584C (en) * 2003-09-19 2015-07-28 Galileo Pharmaceuticals, Inc. Use of alpha-tocotrienol for treatment of mitochondrial diseases
EP1687277B1 (en) 2003-11-20 2018-04-04 Janssen Pharmaceutica NV 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adp-ribose) polymerase inhibitors
MXPA06005686A (es) 2003-11-20 2006-08-17 Janssen Pharmaceutica Nv 2-quinolinonas y 2-quinoxalinonas 7-fenilaquilo sustituidas como inhibidores de la poli(adp-ribosa)polimerasa.
ES2238015B1 (es) * 2004-01-30 2006-11-01 Cepa Schwarz Pharma, S.L. Derivados de cicloalcanodionas con actividad neuroprotectora.
SG154432A1 (en) * 2004-06-30 2009-08-28 Janssen Pharmaceutica Nv Quinazolinedione derivatives as parp inhibitors
CA2569826C (en) 2004-06-30 2013-07-16 Janssen Pharmaceutica N.V. Substituted 2-alkyl quinazolinone derivatives as parp inhibitors
EA014955B1 (ru) 2004-06-30 2011-04-29 Янссен Фармацевтика Н. В. Производные фталазина в качестве ингибиторов parp
DE102004032277A1 (de) * 2004-07-02 2006-01-19 Basell Polyolefine Gmbh Verfahren zur racemoselektiven Synthese von ansa-Metallocenen
PA8663501A1 (es) 2005-02-17 2006-11-09 Wyeth Wyeth Derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilcondensados
KR20080008378A (ko) * 2005-04-22 2008-01-23 와이어쓰 크로만 및 크로멘 유도체 및 이의 용도
WO2008015538A2 (en) * 2006-07-31 2008-02-07 Schwarz Pharma S.L. Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine
US20080033050A1 (en) * 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US8503431B2 (en) * 2006-08-25 2013-08-06 Wireless Wonders Ltd. Mobile phone related indirect communication system and method
WO2008107478A1 (en) 2007-03-08 2008-09-12 Janssen Pharmaceutica Nv Quinolinone derivatives as parp and tank inhibitors
JP5017703B2 (ja) * 2007-05-16 2012-09-05 住友ゴム工業株式会社 ビードエイペックスおよびタイヤ
US8404713B2 (en) 2007-10-26 2013-03-26 Janssen Pharmaceutica Nv Quinolinone derivatives as PARP inhibitors
ES2367760T3 (es) 2008-03-27 2011-11-08 Janssen Pharmaceutica, N.V. Derivados de quinazolinona como inhibidores de la polimerización de la tubulina.
AU2009228943B2 (en) 2008-03-27 2013-04-04 Janssen Pharmaceutica Nv Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors
PL2817299T3 (pl) 2012-02-24 2019-12-31 Lupin Limited Podstawione związki chromanowe jako modulatory receptorów wapniowych
WO2014102592A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Oxime/substituted quinoxaline-type piperidine compounds and uses thereof
DE102013207163B4 (de) 2013-04-19 2022-09-22 Adidas Ag Schuhoberteil
DE102014220087B4 (de) 2014-10-02 2016-05-12 Adidas Ag Flachgestricktes Schuhoberteil für Sportschuhe
EP3397643A1 (en) 2015-12-30 2018-11-07 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Pt(IV) PRODRUGS

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) * 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GB1599296A (en) * 1977-07-06 1981-09-30 Brewster D L Ice making machine
GR71865B (xx) * 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) * 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4239348A (en) * 1979-11-30 1980-12-16 Hughes Aircraft Company High resolution AC silicon MOS light-valve substrate
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
SK282402B6 (sk) * 1993-08-19 2002-01-07 Janssen Pharmaceutica N. V. Deriváty dihydrobenzopyránu, spôsob a medziprodukty na ich výrobu, ich použitie a farmaceutický prostriedok na ich báze
US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) * 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US5696653A (en) * 1996-12-13 1997-12-09 Phase Metrics Tooling for holding a head gimbal assembly
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Also Published As

Publication number Publication date
HRP20000340B1 (en) 2008-12-31
MY124586A (en) 2006-06-30
CA2311669C (en) 2010-04-27
CN1280577A (zh) 2001-01-17
CO5011114A1 (es) 2001-02-28
US20030083365A1 (en) 2003-05-01
US6852714B2 (en) 2005-02-08
HUP0004492A3 (en) 2002-04-29
WO1999029687A8 (en) 2000-04-13
EE200000328A (et) 2001-08-15
CA2311669A1 (en) 1999-06-17
HU224813B1 (en) 2006-02-28
BG64624B1 (bg) 2005-09-30
CZ297895B6 (cs) 2007-04-25
EP1036073B8 (en) 2006-11-15
ID24616A (id) 2000-07-27
TW577886B (en) 2004-03-01
SK8032000A3 (en) 2001-02-12
HUP0004492A2 (hu) 2002-03-28
NO320727B1 (no) 2006-01-23
HRP20000340A2 (en) 2001-04-30
CN1155597C (zh) 2004-06-30
CZ20002018A3 (cs) 2000-10-11
IL136529A (en) 2003-03-12
EA200000616A1 (ru) 2000-12-25
JP2001525407A (ja) 2001-12-11
PL341007A1 (en) 2001-03-12
ATE334125T1 (de) 2006-08-15
ES2270541T3 (es) 2007-04-01
AU748669B2 (en) 2002-06-06
WO1999029687A1 (en) 1999-06-17
KR20010031010A (ko) 2001-04-16
NZ503603A (en) 2001-10-26
HK1028400A1 (en) 2001-02-16
DE69835372D1 (de) 2006-09-07
TR200001542T2 (tr) 2001-01-22
UA70308C2 (uk) 2004-10-15
AU2412799A (en) 1999-06-28
PL191144B1 (pl) 2006-03-31
US20030149093A1 (en) 2003-08-07
EE04438B1 (et) 2005-02-15
US6747045B2 (en) 2004-06-08
DE69835372T2 (de) 2007-08-09
AR017195A1 (es) 2001-08-22
US6495547B1 (en) 2002-12-17
US6133277A (en) 2000-10-17
KR100591605B1 (ko) 2006-06-20
NO20002074D0 (no) 2000-04-19
EP1036073B1 (en) 2006-07-26
EP1036073A1 (en) 2000-09-20
IL136529A0 (en) 2001-06-14
EA003365B1 (ru) 2003-04-24
SK286268B6 (sk) 2008-06-06
BR9814256A (pt) 2000-10-03
BG104372A (en) 2000-12-29
NO20002074L (no) 2000-06-02

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