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ZA976724B - Novel tetrapeptides as antitumor agents - Google Patents

Novel tetrapeptides as antitumor agents

Info

Publication number
ZA976724B
ZA976724B ZA976724A ZA976724A ZA976724B ZA 976724 B ZA976724 B ZA 976724B ZA 976724 A ZA976724 A ZA 976724A ZA 976724 A ZA976724 A ZA 976724A ZA 976724 B ZA976724 B ZA 976724B
Authority
ZA
South Africa
Prior art keywords
antitumor agents
tetrapeptides
novel
novel tetrapeptides
antitumor
Prior art date
Application number
ZA976724A
Other languages
English (en)
Inventor
Teresa Barlozzari
Andreas Haupt
Bernd Janssen Chris Griesinger
Daniel Belik
Michael Boretzky
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ZA976724B publication Critical patent/ZA976724B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA976724A 1996-07-30 1997-07-29 Novel tetrapeptides as antitumor agents ZA976724B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/688,335 US5939527A (en) 1996-07-30 1996-07-30 Tetrapeptides as antitumor agents

Publications (1)

Publication Number Publication Date
ZA976724B true ZA976724B (en) 1999-01-29

Family

ID=24764023

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA976724A ZA976724B (en) 1996-07-30 1997-07-29 Novel tetrapeptides as antitumor agents
ZA976723A ZA976723B (en) 1996-07-30 1997-07-29 Novel tetrapeptides as antitumor agents

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA976723A ZA976723B (en) 1996-07-30 1997-07-29 Novel tetrapeptides as antitumor agents

Country Status (7)

Country Link
US (1) US5939527A (xx)
EP (1) EP0920325A3 (xx)
JP (1) JP2002512590A (xx)
AU (1) AU4296597A (xx)
TW (1) TW491856B (xx)
WO (1) WO1998004278A2 (xx)
ZA (2) ZA976724B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU689131B2 (en) * 1993-10-01 1998-03-26 Teikoku Hormone Mfg. Co., Ltd. Novel peptide derivative
WO2000024392A1 (fr) * 1998-10-26 2000-05-04 Sumitomo Pharmaceuticals Company, Limited Inhibiteur de la formation de beta-amyloide
WO2000051998A1 (en) 1999-03-02 2000-09-08 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as reversible inhibitors of cathepsin s
US6323315B1 (en) * 1999-09-10 2001-11-27 Basf Aktiengesellschaft Dolastatin peptides
US6420364B1 (en) 1999-09-13 2002-07-16 Boehringer Ingelheim Pharmaceuticals, Inc. Compound useful as reversible inhibitors of cysteine proteases
EP2289549A3 (en) 1999-10-01 2011-06-15 Immunogen, Inc. Immunoconjugates for treating cancer
WO2006122408A1 (en) 2005-05-18 2006-11-23 Aegera Therapeutics Inc. Bir domain binding compounds
WO2007008848A2 (en) 2005-07-07 2007-01-18 Seattle Genetics, Inc. Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus
AU2006269422B2 (en) 2005-07-07 2012-12-06 Seagen Inc. Monomethylvaline compounds having phenylalanine side-chain modifications at the C-terminus
CA2652455C (en) 2006-05-16 2017-06-13 Aegera Therapeutics Inc. Iap bir domain binding compounds
NZ602368A (en) 2010-02-12 2014-10-31 Pharmascience Inc Iap bir domain binding compounds
CN118119409A (zh) 2021-09-03 2024-05-31 东丽株式会社 癌的治疗和/或预防用药物组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US4879278A (en) * 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
US6004934A (en) * 1991-08-09 1999-12-21 Teikoku Hormone Mfg. Co., Ltd. Tetrapeptide derivative
CA2136339C (en) * 1992-05-20 2008-02-05 Andreas Haupt Derivatives of dolastatin
PL178766B1 (pl) * 1992-12-16 2000-06-30 Basf Ag Nowe peptydy
US5530097A (en) * 1994-08-01 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory peptide amides
US5504191A (en) * 1994-08-01 1996-04-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide methyl esters
US5554725A (en) * 1994-09-14 1996-09-10 Arizona Board Of Regents Acting On Behalf Of Arizona State University Synthesis of dolastatin 15
US5599902A (en) * 1994-11-10 1997-02-04 Arizona Board Of Regents Acting On Behalf Of Arizona State University Cancer inhibitory peptides
US5663149A (en) * 1994-12-13 1997-09-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides

Also Published As

Publication number Publication date
AU4296597A (en) 1998-02-20
JP2002512590A (ja) 2002-04-23
TW491856B (en) 2002-06-21
ZA976723B (en) 1999-02-12
EP0920325A3 (en) 2003-06-04
US5939527A (en) 1999-08-17
WO1998004278A2 (en) 1998-02-05
WO1998004278A3 (en) 2003-04-17
EP0920325A2 (en) 1999-06-09

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