[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ZA955826B - Dinucleoside-5',5'pyrophosphates - Google Patents

Dinucleoside-5',5'pyrophosphates

Info

Publication number
ZA955826B
ZA955826B ZA955826A ZA955826A ZA955826B ZA 955826 B ZA955826 B ZA 955826B ZA 955826 A ZA955826 A ZA 955826A ZA 955826 A ZA955826 A ZA 955826A ZA 955826 B ZA955826 B ZA 955826B
Authority
ZA
South Africa
Prior art keywords
riboside
dideoxy
pyrophosphates
azido
dinucleoside
Prior art date
Application number
ZA955826A
Other languages
English (en)
Inventor
Antonio De Flora
Umberto Benatti
Marco Giovine
Original Assignee
Lepetit Spa
Univ Degli Studi Genova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa, Univ Degli Studi Genova filed Critical Lepetit Spa
Publication of ZA955826B publication Critical patent/ZA955826B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Adhesives Or Adhesive Processes (AREA)
ZA955826A 1994-07-15 1995-07-13 Dinucleoside-5',5'pyrophosphates ZA955826B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94202059 1994-07-15

Publications (1)

Publication Number Publication Date
ZA955826B true ZA955826B (en) 1996-02-21

Family

ID=8217039

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA955826A ZA955826B (en) 1994-07-15 1995-07-13 Dinucleoside-5',5'pyrophosphates

Country Status (15)

Country Link
US (2) US6040297A (es)
EP (1) EP0773951B1 (es)
JP (1) JPH10502655A (es)
AT (1) ATE177431T1 (es)
AU (1) AU688552B2 (es)
CA (1) CA2195091A1 (es)
DE (1) DE69508255T2 (es)
ES (1) ES2129893T3 (es)
FI (1) FI970081A0 (es)
HU (1) HUT76331A (es)
IL (1) IL114520A0 (es)
NO (1) NO965483L (es)
NZ (1) NZ290127A (es)
WO (1) WO1996002554A1 (es)
ZA (1) ZA955826B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU738907C (en) * 1997-02-06 2002-05-16 Merck Sharp & Dohme Corp. Dinucleotides and their use
US7078391B2 (en) * 1997-02-10 2006-07-18 Inspire Pharmaceuticals, Inc. Method of treating edematous retinal disorders
US7223744B2 (en) 1997-02-10 2007-05-29 Inspire Pharmaceuticals, Inc. Pharmaceutical formulation comprising dinucleoside polyphosphates and salts thereof
US6818629B2 (en) 1997-02-10 2004-11-16 Inspire Pharmaceuticals, Inc. Pharmaceutical formulation comprising P1-(2'-deoxycytidine 5'-)P4-(uridine 5'-) tetraphosphate
US6596725B2 (en) 1997-02-10 2003-07-22 Inspire Pharmaceuticals, Inc. Use of certain dinucleotides to stimulate removal of fluid in retinal detachment and retinal edema
AU6551800A (en) * 1999-08-17 2001-03-13 Adani, Alexander Dinucleoside 5',5'-tetraphosphates as inhibitors of viral reverse transcriptasesand viruses
BRPI0003386B8 (pt) * 2000-08-08 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda pró-droga homo ou heterodiméricas úteis no tratamento de doenças ou disfunções mediadas por fosfodiesterases; composições farmacêuticas contendo a pró-droga ou seus sais farmacêuticos aceitáveis; processo de obtenção destas pró-drogas
US6555675B2 (en) 2000-08-21 2003-04-29 Inspire Pharmaceuticals, Inc. Dinucleoside polyphosphate compositions and their therapuetic use as purinergic receptor agonists
US6867199B2 (en) 2000-08-21 2005-03-15 Inspire Pharmaceuticals, Inc. Dinucleoside polyphosphate compositions and their therapeutic use
EP1365745A2 (en) 2001-02-15 2003-12-03 King Pharmaceuticals, Inc. Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US7790037B2 (en) * 2003-06-25 2010-09-07 University of Pittsburgh—of the Commonwealth System of Higher Education Separation of compounds using tagging moieties including varying numbers of repeat units
KR20220057566A (ko) 2019-09-05 2022-05-09 미토레인보우 테라퓨틱스, 인크. 미토콘드리아 dna 고갈 장애의 치료

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3321462A (en) * 1963-07-15 1967-05-23 Syntex Corp Process for the preparation of nucleoside polyphosphates
US3506478A (en) * 1968-08-29 1970-04-14 Budd Co Method of balancing a brake drum
US4855304A (en) * 1985-01-10 1989-08-08 Repligen Corporation Dinucleoside pyrophosphates and pyrophosphate homologs as plant antivirals
US5159067A (en) * 1987-01-28 1992-10-27 University Of Georgia Research Foundation Inc. 5'-Diphosphohexose nucleoside pharmaceutical compositions
CA1330794C (en) * 1987-03-27 1994-07-19 Phillip Frost Anti-viral compounds, dosage forms and methods
IL86650A0 (en) * 1987-06-30 1988-11-30 Biophor Corp Animal derived cells and liposomes,having an antigenic protein incorporated into their membrane
AU4667189A (en) * 1988-12-05 1990-06-26 Schering Corporation Antiviral dimers and trimers
NZ233197A (en) * 1989-04-13 1991-11-26 Richard Thomas Walker Aromatically substituted nucleotide derivatives, intermediates therefor and pharmaceutical compositions
ATE157879T1 (de) * 1991-06-14 1997-09-15 Europ Communities Transformierte erythrozyten, verfahren zu deren herstellung, und ihre verwendung in pharmazeutischen zusammensetzungen
US5521161A (en) * 1993-12-20 1996-05-28 Compagnie De Developpment Aguettant S.A. Method of treating HIV in humans by administration of ddI and hydroxycarbamide

Also Published As

Publication number Publication date
WO1996002554A1 (en) 1996-02-01
NO965483L (no) 1997-01-28
DE69508255D1 (de) 1999-04-15
FI970081A7 (fi) 1997-01-08
MX9700360A (es) 1998-03-31
NZ290127A (en) 1998-05-27
FI970081L (fi) 1997-01-08
HUT76331A (en) 1997-08-28
CA2195091A1 (en) 1996-02-01
IL114520A0 (en) 1995-11-27
ATE177431T1 (de) 1999-03-15
EP0773951A1 (en) 1997-05-21
FI970081A0 (fi) 1997-01-08
EP0773951B1 (en) 1999-03-10
HU9700118D0 (en) 1997-02-28
US6040297A (en) 2000-03-21
DE69508255T2 (de) 1999-10-14
NO965483D0 (no) 1996-12-19
AU3076695A (en) 1996-02-16
ES2129893T3 (es) 1999-06-16
US6080731A (en) 2000-06-27
JPH10502655A (ja) 1998-03-10
AU688552B2 (en) 1998-03-12

Similar Documents

Publication Publication Date Title
ZA955826B (en) Dinucleoside-5',5'pyrophosphates
IT8421982A0 (it) Strumento per l'estrazione di corpi estranei da canali fisiologici dell'organismo.
HK1038744A1 (zh) 用於治療炎性疾病的化合物
ATE253586T1 (de) 2-(purin-9-yl)-tetrahydrofuran-3,4-diol-derivat
AP2000001947A0 (en) Novel crystalline forms of an antiviral benzidazole compound.
CA2174494A1 (en) Benzofurans
IT8419316A0 (it) Dispositivo per variare la flessibilita' particolarmente per scarpe da sci.
IL60880A (en) Benzophenone hydrazones,their preparation and pesticidal compositions containing them
KR960009930B1 (en) 5'-phosphonates of 3'-azido-2,'3'-dideoxynucleosides
NZ224189A (en) 6-substituted 2',3'-dideoxynucleosides and pharmaceutical compositions
ES8604258A1 (es) Un procedimiento para preparar una adenosina sustituida en n6
MX9800049A (es) Antraquinonas mono- y disulfo-substituidas y su uso para el tratamiento de trastornos de la matriz del hueso.
IT1136889B (it) Mietitrebbiatrice per l'ottenimento di mais da granella
NO952576D0 (no) Vanillin- og/eller etylvanillinperler og fremgangsmåte for deres fremstilling
IT1241631B (it) "n,n'-ditrimetossibenzoilpiperazine 2-sostituite, procedimento per la loro preparazione e composizioni terapeutiche che le contengono
CA2133144A1 (en) Vitamin d3-analogs
AU3189199A (en) Antisense modulation of lfa-3
FR2477837B1 (fr) Composition herbicide a base de derive thiocarbamate de 4-amino-3-methyl-6-phenyl-1,2,4-triazine-5-(4h)one ainsi que l'application de cette composition a la destruction des plantes indesirables
DK406589D0 (da) Middel til behandling af maligne tumorer, indeholdende 8-chloradenosin-3',5'-cyclisk phosphat, 8-aminoacenosin-3',5'-cyclisk phosphat
IL74388A (en) 2,3,4,5-tetrahydro-11-phenyl-1h-(1,4)diazepino(1,7-a)indoles,their production and pharmaceutical compositions containing them
DE3878988D1 (de) 1,2-di(4-isobutylphenyl)aethylen, dessen herstellung und verwendung als zwischenprodukt.
FR2654429B1 (fr) Nouveaux derives du methyl-2-propionate de 3,3,5-trimethylcyclohexanol, leur procede de preparation ainsi que compositions therapeutiques les contenant.
FR2572080B1 (fr) Procede de preparation de compositions de mucopolysaccharides dotees d'une activite antithrombotique elevee, les compositions obtenues et leur application en tant que medicaments
IT8721354A0 (it) Procedimento per la realizzazione di dadi filettati, nonche' prodotto semilavorato per la produzione di dadi filettati.
GR3024709T3 (en) Novel cytarabine derivatives, their production and use